• Journal of Microbiology and Biotechnology
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• v.27 no.6
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• pp.1078-1089
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• 2017

Biofilm formation of Staphylococcus aureus is one of its mechanisms of drug resistance. Anti-biofilm screening of 106 compounds from marine-derived fungi displayed that 12 compounds inhibited S. aureus biofilm formation by >50% at the concentration of $100{\mu}g/ml$, and only secalonic acid D (SAD) and B inhibited by >90% at $6.25{\mu}g/ml$ without inhibiting cell growth after 24-h incubation. Meanwhile, it was found that the double bond between C-1 and C-10 of citrinin derivatives and the C-C connection position of two chromone monomers may be important for their anti-biofilm activities. Moreover, SAD slightly facilitated biofilm eradication and influenced its architecture. Furthermore, SAD slowed the cell growth rate in the preceding 18-h incubation and differentially regulated transcriptional expression of several genes, such as agr, isaA, icaA, and icaD, associated with biofilm formation in planktonic and biofilm cells, which may be the reason for the anti-biofilm activity of SAD. Finally, SAD acted synergistically against S. aureus growth and biofilm formation with other antibiotics. These findings indicated that various natural products from marine-derived fungi, such as SAD, could be used as a potential biofilm inhibitor against S. aureus.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.16 no.10
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• pp.2113-2120
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• 2012

The study of automatic monitoring and analysis of marine environment in Korea is not enough. Recently, the marine monitoring technology is actively being studied since the sea is a rich repository of natural resources that is taken notice in the world. In particular, the marine environment data should be collected continuously in order to understand and analyze the marine environment, however the marine environment monitoring is limited in many area yet. The prediction of marine disaster by automatic collecting marine environment data and analyzing the collected data can contribute to minimized the damages with respect to marine pollution of oil spill and fisheries damage by red tide blooms and marine environment upsets. In this paper, we proposed the marine environment monitoring and analysis system model. The proposed system automatically collects the marine environment information for monitoring the marine environment intelligently. Also it predicts the marine disaster by analyzing the collected ocean data.

• Journal of the Korean Society of Marine Environment & Safety
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• v.18 no.2
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• pp.131-138
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• 2012

The tourism industry is considered as the world largest industry and it is assessed as the most effective way to create employment. In particular, the marine tourism industry such as marine leisure sports, cruise can create high added value so that its significance has been more emphasized. Korea has natural tourist attractions such as more than 3,000 islands, about 12,000km lengths coastline, wide wetlands and beautiful seascape. In addition, the establishment of the five-day workweek and the development of means of transportation make the policy demand of the public for marine tourism increase continuously. However, Korea currently lacks policy and system for revitalizing marine tourism industry as the new growth engine and has not made good use of its retained tourist resource. Accordingly, this study explores the current situation and challenges of Korean marine tourism industry and further analyses the limits of the national legal systems for marine tourism. Lastly, it suggests policy recommendation for promoting marine tourism industry.

• Journal of Food Hygiene and Safety
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• v.36 no.6
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• pp.455-473
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• 2021

In order to aid the researchers who analyze the biotoxins in marine molluscs, this paper introduces the official names and ecological characteristics of the domestically produced or distributed bivalve and gastropods that can be contaminated with marine biotoxins. Also, the paper intends to inform the location and scientific name of each organ of the representative group of species through anatomical maps. In the future, it is necessary to standardize and normalize the names of the species and the research institutions in food codes, scholarly papers and reports on the marine biotoxin analysis.

• Proceedings of the Korean Aquaculture Society Conference
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• 2006.05a
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• pp.619-620
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• 2006

• Proceedings of the Korean Aquaculture Society Conference
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• 2006.05a
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• pp.121-122
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• 2006

• Proceedings of the Korean Aquaculture Society Conference
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• 2006.05a
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• pp.119-120
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• 2006

• Proceedings of KOSOMES biannual meeting
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• 2018.06a
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• pp.184-185
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• 2018

• Proceedings of the Malacological Society of Korea Conference
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• 2002.11a
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• pp.21-22
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• 2002

• Korean Journal of Pharmacognosy
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• v.21 no.1
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• pp.1-48
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• 1990

Marine organisms have proven to be rich sources of interesting organic molecules. A great number of compounds with diverse structural features and interesting biological activities have been isolated. Recent studies on secondary metabolites of marine organisms are discussed with a focus on a variety of biological activities and marine natural product literatures are also reviewed.