• Molecules and Cells
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• v.43 no.2
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• pp.126-138
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• 2020

The transcription factor RUNX1 first came to prominence due to its involvement in the t(8;21) translocation in acute myeloid leukemia (AML). Since this discovery, RUNX1 has been shown to play important roles not only in leukemia but also in the ontogeny of the normal hematopoietic system. Although it is currently still challenging to fully assess the different parameters regulating RUNX1 dosage, it has become clear that the dose of RUNX1 can greatly affect both leukemia and normal hematopoietic development. It is also becoming evident that varying levels of RUNX1 expression can be used as markers of tumor progression not only in the hematopoietic system, but also in non-hematopoietic cancers. Here, we provide an overview of the current knowledge of the effects of RUNX1 dosage in normal development of both hematopoietic and epithelial tissues and their associated cancers.

• BMB Reports
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• v.45 no.4
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• pp.259-264
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• 2012

Accumulation of modified nucleotides is defective to various cellular processes, especially those involving DNA and RNA. To be viable, organisms possess a number of (deoxy)nucleotide phosphohydrolases, which hydrolyze these nucleotides removing them from the active NTP and dNTP pools. Deamination of purine bases can result in accumulation of such nucleotides as ITP, dITP, XTP and dXTP. E. coli RdgB has been characterised as a deoxyribonucleoside triphosphate pyrophosphohydrolase that can act on these nucleotides. S. cerevisiae homologue encoded by YJR069C was purified and its (d)NTPase activity was assayed using fifteen nucleotide substrates. ITP, dITP, and XTP were identified as major substrates and kinetic parameters measured. Inhibition by ATP, dATP and GTP were established. On the basis of experimental and published data, modelling and simulation of ITP, dITP, XTP and dXTP metabolism was performed. (d)ITP/(d)XTPase is a new example of enzyme with multiple substrate-specificity demonstrating that multispecificity is not a rare phenomenon

• Korean Journal of Optics and Photonics
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• v.5 no.2
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• pp.319-325
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• 1994

The performance of Manchester-coded DPSK optical wavelength division multiplexing (WDM) systems using a stochastic approach is evaluated taking into account the shot noise and the four-wave mixing (FWM) caused by fiber nonlinearities. The result of Manchester-coded system is compared to conventional non-return-to-zero (NRZ) systems for DPSK modulation formats. Further, the dynamic range, defined as the ratio of the maximum input power (limited by the FWM), to the minimum input power (limited by receiver sensitivity), is evaluated. For $1.55.{\mu}m$16 channel WDM systems, the dynamic range of DPSK Manchester coded systems shows a 2.1 dB improvement with respect to the NRZ. This result holds true for both dispersion-shifted fiber and conventional fiber; it has been obtained for 10 GHz channel spacing, 1 Gbps/channel bit rate.t rate.

• International journal of advanced smart convergence
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• v.8 no.3
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• pp.20-26
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• 2019

This study multi-dimensionally analyzes a sport documentary, All or Nothing: Manchester City, which is an original content on Prime Video, an American Over-The-Top (OTT) platform. Due to the success of South Korean soccer player Heung-min Son who plays Tottenham Hotspur of England, the popularity of the English Premier league is recently the greatest in South Korea along with the fact that soccer has been a popular sport for a long time. This study focuses on the success of the soccer club, Manchester City, which has become a rising star with its huge investment from United Arab Emirates; Manchester City won the league four times since 1992/1993 season. Also, during the 2017/2018 season, the background the documentary, Manchester City won the league title with new records, which shows the greatness of Manchester City. Especially, this study examines the documentary by 1) Story 2) Type of Scene 3) How to watch. Thus, this study explores not only the aspects of team-themed sport documentary that shows how and why Manchester City is excellent, but also the traits of the original content that explores the structure of the media platform.

• Journal of Sensor Science and Technology
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• v.25 no.5
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• pp.303-309
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• 2016

In this paper, we introduce a new method for controlling the illumination of LEDs in visible light communication (VLC) by changing the duty cycle of Manchester code. When VLC data were transmitted in Manchester code, the average optical power of the LEDs was proportional to the duty cycle. In experiments, we controlled the illumination of a $3{\times}3$ LED array from 10% to 90% of its peak value by changing the duty cycle of the Manchester code. The synchronizing clocks required for encoding and decoding the Manchester code were supplied by pulse generators that were connected to a 220 V power line. All pulse generators made the same pulses with a repetition frequency of 120 Hz, and they were synchronized with the full-wave rectified voltage of the power line. This scheme is a very simple and useful method for constructing indoor wireless sensor networks using LED light.

• Journal of the Society of Cosmetic Scientists of Korea
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• v.4 no.1
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• pp.51-67
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• 1974

• Proceedings of the IEEK Conference
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• 2004.06b
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• pp.525-528
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• 2004

Manchester encoder of FSM method is a suitable signal coding for an RFID system. However, Manchester encoder of FSM method has usually more gate count and lower maximum frequency than encoder of exclusive-OR gate method. In this paper. it is proposed encoder of FSM method to improve gate count and maximum frequency.

• Safety and Health at Work
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• v.8 no.3
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• pp.231-236
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• 2017

Vital to the prevention of work-related ill-health (WRIH) is the availability of good quality data regarding WRIH burden and risks. Physician-based surveillance systems such as The Health and Occupation Research (THOR) network in the UK are often established in response to limitations of statutory, compensation-based systems for addressing certain epidemiological aspects of disease surveillance. However, to fulfil their purpose, THOR and others need to have methodologic rigor in capturing and ascertaining cases. This article describes how data collected by THOR and analogous systems can inform WRIH incidence, trends, and other determinants. An overview of the different strands of THOR research is provided, including methodologic advancements facilitated by increased data quantity/quality over time and the value of the research outputs for informing Government and other policy makers. In doing so, the utility of data collected by systems such as THOR to address a wide range of research questions, both in relation to WRIH and to wider issues of public and social health, is demonstrated.

• Proceedings of the Korea Contents Association Conference
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• 2007.11a
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• pp.874-877
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• 2007

본 논문에서는 가전기기, 자동차, 공장 자동화 기기, 컴퓨터 주변기기와 HA(Home Automation)를 위해 Microchip 사의 PIC16F616과 315MHz 대역의 무선 모듈과 KTX-Blue DC 모터를 사용하여 무선 제어 시스템 환경을 설계 하였고, 모터제어를 통해 시스템 동작을 확인하여 315MHz 대역에서 ASK진폭 편이 방식의 무선 통신 기법과 Manchester 부호를 사용하여, 무선 모터 제어 시스템을 설계하였다.

• Journal of Sensor Science and Technology
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• v.29 no.3
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• pp.149-155
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• 2020

In this study, we employed Manchester code for illumination control and flicker prevention of the light-emitting diode (LED) used in a visible light communication (VLC) system. In the VLC transmitter, the duty factor of the Manchester code was utilized for illumination control; in the VLC receiver, the spike signal from an RC-high pass filter was utilized to recover the transmitted signal whilst suppressing the 120-Hz noise arising from adjacent lighting lamps. Instead of the clock being transmitted in a separate channel, a syncmark signal was transmitted in front of each data byte and used as the reference time for transforming the Manchester code to non-return-to-zero (NRZ) data in the receiver. In experiments, the LED illumination was controlled in the range of approximately 12-84% of the constant wave (CW) light via changing of the duty factor from 10% to 90%. This scheme is useful for constructing indoor wireless sensor networks using LED light that is flicker-free and presents capability for illumination control.