• Title/Summary/Keyword: Makoto

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The effectiveness of optical coherence tomography for evaluating peri-implant tissue: A pilot study

  • Sanda, Minoru;Shiota, Makoto;Imakita, Chiharu;Sakuyama, Aoi;Kasugai, Shohei;Sumi, Yasunori
    • Imaging Science in Dentistry
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    • v.46 no.3
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    • pp.173-178
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    • 2016
  • Purpose: Optical coherence tomography (OCT) has been investigated as a novel diagnostic imaging tool. The utilisation of this equipment has been evaluated through several studies in the field of dentistry. The aim of this preliminary study was to determine through basic experiments the effectiveness of OCT in implant dentistry. Materials and Methods: To assess detection ability, we captured OCT images of implants in each of the following situations: (1) implants covered with mucosae of various thicknesses that were harvested from the mandibles of pigs; (2) implants installed in the mandibles of pigs; and (3) implants with abutments and crowns fixed with temporary cement. The OCT images were captured before cementation, after cementation, and after removing the excess submucosal cement. Results: If the thickness of the mucosa covering the implant body was less than 1 mm, the images of the implants were clearly detected by OCT. In the implants were installed in pigs' mandibles, it was difficult to capture clear images of the implant and alveolar bone in most of the samples. Remnants of excess cement around the implants were visible in most samples that had a mucosa thickness of less than 3 mm. Conclusion: Currently, OCT imaging of implants is limited. Cement remnants at the submucosal area can be detected in some cases, which can be helpful in preventing peri-implant diseases. Still, though there are some restrictions to its application, OCT could have potential as an effective diagnostic instrument in the field of implant dentistry as well.

The polarimetric study of (331471) 1984QY1: an asteroid in comet-like orbit

  • Kim, Jooyeon;Ishiguro, Masateru;Bach, Yoonsoo P.;Kuroda, Daisuke;Naito, Hiroyuki;Kim, Yoonyoung;Kwon, Yuna G.;Imai, Masataka;Kuramoto, Kiyoshi;Watanabe, Makoto
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.2
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    • pp.50.2-50.2
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    • 2017
  • Spatial distribution of atmosphereless bodies in the solar system provides an important clue as to their origins, namely asteroids from Mainbelt or comets from outer solar system. It is, however, difficult to distinguish asteroids and dormant comets due to their similar appearances. In this study, we conducted a unique observation to differentiate asteroids and dormant comets in terms of 'polarimetry'. We observed (331471) 1984 QY1 (hereafter QY1) at large phase angles using the Multi-Spectral Imager (MSI) on the 1.6-m Pirka Telescope from UT 2016 May 25 to June 24. QY1 is a dormant comet candidate in terms of the dynamical properties (i.e. the Tisserand parameter with respect to Jupiter, TJ = 2.68). We analyzed the polarization degree of QY1 as a function of phase angle and found its maximum polarization degree, $Pmax=8.68{\pm}0.28%$ and $8.72{\pm}0.38%$, in RC-and V-band, respectively, around the phase angle of ${\alpha}=100^{\circ}$. In addition, we obtained the geometric albedo, $pV=0.16{\pm}0.02$ by means of an empirical slope-albedo law. The polarimetric properties and the albedo value we acquired are similar to those of S-type asteroids rather than cometary nuclei. In this presentation, we introduce our observation and findings. In addition, we further discuss a dynamical transportation process from Mainbelt to the current orbit.

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Spectropolarimetric Signals of Comet 2P/Encke During Its 2017 Apparition

  • Kwon, Yuna Grace;Ishiguro, Masateru;Kuroda, Daisuke;Kawabata, Koji S.;Nakaoka, Tatsuya;Kawabata, Miho;Uemura, Makoto;Shinnaka, Yoshiharu;Akitaya, Hiroshi;collaboration, OISTER
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.2
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    • pp.49.1-49.1
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    • 2017
  • Comets are one of the most primordial solar system objects that hold the information of the early days of solar system formation inside their nuclei. Orbiting the Sun, they spew such ancient materials that have been buried for many years, creating dust and gas comae. Cometary dust grains absorb and scatter sunlight radiating the continuous light, while gas molecules form the line emissions. Eachof the comets has its own light patterns, which depends on the physical and chemical properties of the dust and gas components. In this regard, spectropolarimetrycan be a powerful tool to study the properties of cometary constituents free from contamination of each other. This methodology offers a series of information on the polarization degrees of the dust and gas components as well as on wavelength dependence of the polarization degree and polarization angle of cometary dust simultaneously. Herein, we will report the results of the spectropolarimetric study of comet 2P/Encke, which is one of the well-known objects for its shortest orbital period and its prominent aging signals. We performed a spectropolarimetric observation of comet 2P/Encke in its inbound orbit using the Higashi-Hiroshima Optical and Near-Infrared Camera (HONIR) at the Higashi-Hiroshima Observatory, Japan, on UT 2017 February 21 at high phase angle of =75.7 deg. Ourstudy of this interesting comet is the first and only one done through spectropolarimetry in a referred publication. We will discuss the most recent polarimetric results of our study in terms of 2P/Encke' scurrent evolutionary status.

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Development of equipment for tumor cauterization

  • Hoshino, Hirokazu;Ochiai, Makoto;Sakasegawa, Aya;Hayakawa, Yoshinori
    • Proceedings of the Korean Society of Medical Physics Conference
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    • 2002.09a
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    • pp.474-477
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    • 2002
  • Equipment to cauterize tumors by an electrically heated Kanthal wire is under development. The wire( alloy of iron, chromium and Aluminum) keeps sufficient strength up to 1400 degrees in Celsius. Although AC 50Hz current source is used in the prototype experiment, RF current will be used in future. The diameter of the Kanthal wire was 0.3 mm which was connected to Kanthal wire of 0.8 mm. The thicker wire was used as a leading wire. The possibility of application of the heating wire in combination with an ultrasound endoscope was determined, where ultrasound endoscope is to be used to monitor the location on the wire and an extent of a tumor in digestive organs. This procedure requires the wire to be applied inside ultrasound transmitting media. First, the wire was applied in the degassed water in which a chicken liver sample was submerged. The wire, however, burned out in water soon after it became red-hot at 12 A. The reason is that large current is required for the wire to become red-hot due to strong convection. Starch paste of 3 weight percent was employed instead of water. This made the wire red-hot approximately at 6 A, showing the increased viscosity of the starch decreased the convection and the wire was cover by the steam. The liver sample was cauterized successively, while the location of the wire and the liver was monitored by an ultrasound diagnosis equipment outside the plastic vessel of the starch paste.

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Impact of Reconstructed Gridded Product of Global Wind/Wind-stress Field derived by Satellite Scatterometer Data

  • Koyama, Makoto;Kutsuwada, Kunio;Morimoto, Naoki
    • Proceedings of the KSRS Conference
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    • 2008.10a
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    • pp.309-312
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    • 2008
  • The advent of high resolution products of surface wind and temperature derived by satellite data has permitted us to investigate ocean and atmosphere interaction studies in detail. Especially the Kuroshio extension region of the western North Pacific is considered to be a key area for such studies. We have constructed gridded products of surface wind/wind stress over the world ocean using satellite scatterometer (Qscat/SeaWinds), available as the Japanese Ocean Flux data sets with Use of Remote sensing Observation (J-OFURO). Using new data based on improved algorithm which have been recently delivered, we are reconstructing gridded product with higher spatial resolution. Intercomparison of this product with the previous one reveals that there are some discrepancies between them in short-period and high wind-speed ranges especially in the westerly wind region. The products are validated by not only comparisons with in-situ measurement data by mooring buoys such as TAO/TRITON in the tropical Pacific and the Kuroshio Extension Observation (KEO) buoys, but also intercomparison with numerical weather prediction model (NWPM) products (the NRA-1 and 2). Our products have much smaller mean difference in the study areas than the NWPM ones, meaning higher reliability compared with the NWPM products. Using the high resolution products together with sea surface temperature (SST) data, we examine a new type of relationship between the lower atmosphere and upper ocean in the Kuroshio Extension region. It is suggested that the spatial relation between the wind speed and SST depends upon, more or less, the surrounding oceanic condition.

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Ellagic Acid Inhibits Migration and Invasion by Prostate Cancer Cell Lines

  • Pitchakarn, Pornsiri;Chewonarin, Teera;Ogawa, Kumiko;Suzuki, Shugo;Asamoto, Makoto;Takahashi, Satoru;Shirai, Tomoyuki;Limtrakul, Pornngarm
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.5
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    • pp.2859-2863
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    • 2013
  • Polyphenolic compounds from pomegranate fruit extracts (PFEs) have been reported to possess antiproliferative, pro-apoptotic, anti-inflammatory and anti-invasion effects in prostate and other cancers. However, the mechanisms responsible for the inhibition of cancer invasion remain to be clarified. In the present study, we investigated anti-invasive effects of ellagic acid (EA) in androgen-independent human (PC-3) and rat (PLS10) prostate cancer cell lines in vitro. The results indicated that non-toxic concentrations of EA significantly inhibited the motility and invasion of cells examined in migration and invasion assays. The EA treatment slightly decreased secretion of matrix metalloproteinase (MMP)-2 but not MMP-9 from both cell lines. We further found that EA significantly reduced proteolytic activity of collagenase/gelatinase secreted from the PLS-10 cell line. Collagenase IV activity was also concentration-dependently inhibited by EA. These results demonstrated that EA has an ability to inhibit invasive potential of prostate cancer cells through action on protease activity.

Fuku shin, a Kampo diagnostic procedure, could be one of useful diagnostic tools for anxiety disorders and depression

  • Arai, Young-Chang P.;Nishihara, Makoto;Sato, Jun;Ushida, Takahiro;Morimoto, Atsuko;Sakurai, Hiroki;Ohmichi, Yusuke;Makino, Izumi;Suzuki, Chiharu
    • CELLMED
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    • v.2 no.2
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    • pp.15.1-15.3
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    • 2012
  • Kampo medicine, a Japanese traditional herbal medicine, has been used in clinical practice in Japan. The most appropriate Kampo formula should be chosen for each individual by the four diagnostic procedures. Fuku shin, the abdominal exam, is one of the most important approaches in the procedures. There are several abdominal conformations (signs) when administering Fuku shin. In Kampo medicine, psychiatric illness-marked by depression and anxiety-has been shown to be related with an abdominal conformation, Shin ka hi koh (Epigastric Obstructive Hardness). The aim was to see the occurrence of abdominal conformations in each level of depression and anxiety symptoms. Two hundred fifteen patients were assigned to high-, moderate-, or low-level psychiatric comorbidity based on the Hospital Anxiety and Depression Scale and were studied regarding the occurrence of major abdominal conformations. Moderate and high psychopathological groups showed the higher occurrence of Shin ka hi koh [Low, 21%; Moderate, 67%; High, 74%] ($p$ < 0.0001). In conclusion, moderate and high psychopathological patients showed the higher occurrence of a specific abdominal sign.

Olanzapine Attenuates Mechanical Allodynia in a Rat Model of Partial Sciatic Nerve Ligation

  • Fukuda, Taeko;Yamashita, Soichiro;Hisano, Setsuji;Tanaka, Makoto
    • The Korean Journal of Pain
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    • v.28 no.3
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    • pp.185-192
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    • 2015
  • Background: Neuropathic pain is a global clinical problem; nevertheless, nerve injury treatment methods remain limited. Olanzapine has antinociceptive and anti-nueropathic properties; however, its preventive effects have not been assessed in nerve injury models. Methods: We prepared a partial sciatic nerve ligation (Seltzer model) or sham-operated model in male Sprague-Dawley rats under isoflurane anesthesia. In a pre-treatment study, we administered olanzapine (10 mg/kg) intraperitoneally 1 h before nerve ligation. In post-treatment and dose-dependent studies, we injected 3 different doses of olanzapine intraperitoneally 1 h after nerve ligation. Mechanical allodynia was measured before and 7 days after surgery. Immunohistochemical analysis using anti-Iba-1 antibody was used to assess the effect of olanzapine at the spinal level. Results: In the pre-treatment study, median withdrawal thresholds of the normal saline groups were significantly lower than those of the sham-operated groups; however, those of the olanzapine (10 mg/kg) and sham-operated groups were not different. In the post-treatment and dose-dependent studies, the median withdrawal thresholds of the olanzapine (2.5 mg/kg) and normal saline groups were not different; however, those of the olanzapine (10 and 50 mg/kg) groups were significantly higher than those of the normal saline groups. Olanzapine did not have a significant effect on the density of Iba-1 staining. Conclusions: Olanzapine attenuated mechanical allodynia dose-dependently in the Seltzer model. This anti-allodynic effect of olanzapine was observed even when injected 1 h after nerve ligation. This effect of olanzapine appeared to be unrelated to microglia activation in the ipsilateral dorsal horn of the lumbar spinal cord.

MBE growth of topological insulator $Bi_2Se_3$ films on Si(111) substrate

  • Kim, Yong-Seung;Bansa, Namrata;Edrey, Eliav;Brahlek, Mathew;Horibe, Yoichi;Iida, Keiko;Tanimura, Makoto;Li, Guo-Hong;Feng, Tian;Lee, Hang-Dong;Gustafsson, Torgny;Andrei, Eva;Cheong, Sang-Wook;Oh, Seong-Shik
    • Proceedings of the Korean Vacuum Society Conference
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    • 2011.02a
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    • pp.59-59
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    • 2011
  • We will report atomically sharp epitaxial growth of $Bi_2Se_3$ three-dimensional topological insulator films on Si(111) substrate with molecular beam epitaxy (MBE). It was achieved by employing two step growth temperatures to prevent any formation of second phase, like as $SiSe_2$ clusters, between $Bi_2Se_3$ and Si substrate at the early stage of growth. The growth rate was determined completely by Bi flux and the Bi:Se flux ratio was kept ~1:15. The second-phase-free atomically sharp interface was verified by RHEED, TEM and XRD. Based on the RHEED analysis, the lattice constant of $Bi_2Se_3$ relaxed to its bulk value during the first quintuple layer implying the absence of strain from the substrate. Single-crystalline XRD peaks of $Bi_2Se_3$ were observed in films as thin as 4 QL. TEM shows full epitaxial structure of $Bi_2Se_3$ film down to the first quintuple layer without any second phases. This growth method was used to grow high quality epitaxial $Bi_2Se_3$ films from 3 QL to 3600 QL. The magneto-transport properties of these thin films show a robust 2D surface state which is thickness independent.

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Fabrication of the thermopile using SOI structure (SOI 구조를 이용한 열전쌍열(Thermopile) 제작)

  • Lee, Young-Tae;Takao, Hidekuni;Ishida, Makoto
    • Journal of Sensor Science and Technology
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    • v.11 no.1
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    • pp.1-8
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    • 2002
  • In this paper, a thermopile which is applied to wide uses of temperature measuring was fabricated and its characteristic was improved by appling SOI structure to the fabrication. We improved characteristic of the thermopile by using single crystal silicon strips that has high seebeck coefficient and dielectric isolating the silicon strips from substrate with silicon dioxide film which dramatically decrease thermal conductivity between hot and cold junction compared to a silicon strip which was fabricated by ion implantation. The thermopile consists of 17 p-type single crystal silicon strips and 17 n-types by serial connection. The result of electromotive force measuring showed very good characteristic as 130mV/K when temperature difference between the two ends of the thermopile occurs by applying light on the thermopile fabricated with silicon strips of $1600{\mu}m$ length, $40{\mu}m$ width, $1{\mu}m$ thickness.