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Effects of Alcohol on Neurocognitive Function, Psychomotor Performance and Subjective Response in Koreans with Different ALDH2 Genotypes (한국인에서 Aldehyde Dehydrogenase 2 유전자 변이가 알코올의 신경인지 기능, 정신운동성 수행 및 주관적 반응에 미치는 영향)

  • Shin, Il-Seon;Yoon, Jin-Sang;Kim, Hyun;Yoon, Bo-Hyun;Lee, Hoon;Jung, Jae-Sung;Lee, Hyung-Yung
    • Korean Journal of Biological Psychiatry
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    • v.6 no.2
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    • pp.176-188
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    • 1999
  • Objective : The purpose of this study was to evaluate the effects of alcohol on neurocognitive function, psychomotor performance and subjective response in healthy Korean adults with different ALDH2 genotypes. Method : A total of 24 males, half with active $ALDH2^*1/2^*1$ and the other with inactive $ALDH2^*1/2^*2$, was selected through genotyping using restriction fragment length polymorphism. In a double-blind, placebo-controlled cross-over design, each subject consumed 0.5g/kg dose of alcohol, given as a mixture of 40% vodka and orange juice, and placebo(orange juice) on two separate occasions on an average of weekly intervals. The blood alcohol concentrations(BACs) were measured using a breath analyzer at baseline and at 30, 60 minutes after drinking. P300s were measured at baseline and at 30 minutes after alcohol and placebo intake. Vital signs and psychomotor performance[Critical Flicker Fusion Threshold(CFFT), Choice Reaction Time (CRT), Digit Symbol Substitution(DSS)] were measured at baseline and at 60 minutes after alcohol and placebo intake. Subjective responses were measured at the end of the study. The statistical analysis focused on whether there were any differences between groups with different ALDH2 genotypes. Results : The major results are as follows. 1) BACs in the inactive group were overall equivalent to those in the active group. Only in terms of time, BACs were significantly higher overall at 30 minutes than at 60 minutes after alcohol intake. 2) Pulse rates were significantly increased after alcohol intake compared with placebo, and the increase was greater in the inactive than in the active group. 3) P300 latencies in leads Fz(frontal), Cz(cental) and Pz(parietal) were significantly increased after alcohol intake compared to placebo, and the increase was greater in the inactive than in the active group. P300 amplitudes in leads Cz and Pz were significantly decreased overall after alcohol intake compared to placebo. 4) Compared with placebo, alcohol produced significant effect on the psychomotor performance : impairment in the inactive group, improvement in the active group. 5) Compared with placebo, alcohol significantly induced a negative or an intense effect on the subjective responses in the inactive group, but little negative and even a somewhat positive effect in the active group. Conclusions : These results suggest that ALDH isozyme variance might be an important factor to determine the effects of acute dose of alcohol on the various psychobehavioural functions and also to determine the alcohol use pattern and to predict the future development of alcohol overuse and/or abuse.

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The Current Status of Use and the Difference of Awareness by User Groups in the Cheongryongsan Vegetable Garden Park (청룡산 텃밭공원의 이용실태와 이용주체간 의식 차이)

  • Son, Yong-Hoon;Lim, Jung-Eon
    • Journal of Korean Society of Rural Planning
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    • v.20 no.2
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    • pp.71-80
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    • 2014
  • This study intended for Cheongryongsan Community Garden in Gwanak-gu, one of the demonstration places for 'Community Garden' Project recently implemented by the Seoul Government. This study had two major purposes: investigating the current status of the management and usage and identifying its characteristics; investigating users' awareness to consider the construction and operation directions of sustainable community gardens. This study was conducted based on several surveys such as an investigation into the spatial configuration and the management system of parks through a field study, a use survey through a questionnaire survey for vegetable garden users and an awareness survey about the construction direction of gardens direction preferred by users through the analytical hierarchy process (AHP). As a result of a questionnaire survey for vegetable garden users, the usage status was summarized as follows: Considering the common trends in the 2012 and the 2013 user survey, women used Cheongryongsan Vegetable Garden more than men. Over fifties used it most of all users. Users were mostly neighborhood residents. They used to visit there three to five times a week and stayed for about 30 minutes to one hour. Users differently responded to the question related to the order of priority for the use of the garden in the 2012 and the 2013 survey. They had increasingly used it for individuals' production activities more than social exchanges. As a result of making an AHP analysis for general park users, vegetable garden users there were clear differences in the targets which each subject put emphasis on in relation to the construction and operation of vegetable gardens. General park users recognized a vegetable garden as a park where park functions and the functions of the vegetable garden coexisted. On the other hand, vegetable garden users viewed it as a space where they attached importance to the functions of the vegetable garden like an allotment. Last, this study contemplated subjects related to the construction and operation of vegetable gardens which had to be considered in the future. Vegetable gardens tended to be biased as personal hobby places. It was viewed that the main reason was insufficient support activities for vegetable garden education and exchange programs originally planned when vegetable gardens had been constructed. Vegetable garden users recognized vegetable gardens as places for individuals' farming activities like allotments. For the desirable operation of vegetable gardens, it would be necessary to give priority to the park management before the production activities in individuals' vegetable gardens. The important role of the government would be to build the base through the provision of education and opportunities so that a local resident organization could actively participate in the management of a vegetable garden after a vegetable garden was constructed. It would be necessary to make a use survey and an awareness survey for users conducted in this study on a regular basis because the surveys could be important basic data in the decision-making process for the sustainable operations of the vegetable garden.

The analysis of the foreign laws related to landscape architecture and a study on the reasonable application to the expected organic law for landscape architecture in Korea (외국의 조경관련 법제도의 비교분석과 한국에서의 조경기본법 제정을 위한 합리적 적용에 관한 연구)

  • 신익순
    • Journal of the Korean Institute of Landscape Architecture
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    • v.25 no.3
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    • pp.66-88
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    • 1997
  • There is no special law of Landscape architecture in Korea. So, examining the concept from the legal basis of LA with the viewpoint of a natural scientist not a jurist, this study was conducted to grasp the present condition of the name and the related text of the foreign laws in force which were connected with LA.. And those foreign laws were arranged in the name and the text and classified by nations of regional groups and it was considered to the mutual relation with lots of laws which are scattered with the various laws. Current domestic regulations to the various fields of LA are assembled with the many related rules. The governmental organization conducting those business is nonexistent up to now and it is generally known to except the dept. of LA from the office organization in Korea. Being at a disadvantage as mentioned above, this study was progressed under the necessity of the scientific basis for the expected organic law of LA proposed to establish it by every field of LA. Though feels inconvenience if the study for the items itself of LA had been proceeded prior to the study of laws relating to LA throughout the study, such a extensive study will be a subject to be attempted constantly hereafter by all part of landscape architects. The contents of the study are as follows ; 1. The present condition of the foreign laws connected with LA 1. The proposal & analysis of the problems and the solutions to the domestic laws connected with LA 3. The proposal of the reasonable application pklan in order to establish the organic law for LA. Among the items relating to LA such as engineer, contract, planning, design and supervision, construction, maintenance, plant and planting, open space, facilities, aesthetics and sight, park, land use and development planning, urban and regional planning, leisure space planning, environmental conservation and ecology, structural engineering of construction, administration, right and penal regulations, the laws dealing with the matter relating to LA directly or indirectly are prescribed dispersedly in the many other related laws and it is concluded to be impossible for the independent law of LA is likely to be establish with not only selecting and arranging the matter having closed connections to LA directly but also being recognized as the systematic equipment of the LA business. It was to be analyzed the present condition of the collected foreign laws relating to LA. After pointing out the problems to the domestic related laws being at issue, the remedies for it were presented through the questionnaire of the landscape specialist in which the supporting opinions to the recognition to the problems and the solutions were come to a major portion. Three types of application such as applicable, non-applicable, applicable after examination were presented to decide whether or not the foreign related laws were applied to the domestic one. The result of analysis shows that 42 statutes and 9 ordinances are applicable, 4 statutes and 7 ordinances are non-applicable, 1 constitution, 81 statutes and 48 ordinances are applicable after examination.

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Reliability and Validity of the Behavioral Observation Method for Assessing Low Back Pain in Patients with Spinal Diseases (척추질환자의 요통사정을 위한 통증행위 관찰법의 신뢰도 및 타당도 검정)

  • Yoon, Ho-Soon;Lee, Eun-Ok
    • Journal of muscle and joint health
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    • v.1 no.1
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    • pp.97-115
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    • 1994
  • The purpose of this study was to examine the reliability and validity of the observed behaviors of subjects who suffered from low back pain with spinal diseases, Thirty two low back pain patients admitted on the neurosurgical unit in an army hospital were compared with 30 normal controls belonged to an army unit, by means of matching the age, hight and weight. Observed pain behaviors were developed by the researcher on the bases of literature and patient observation. This tool consists of 18 behaviors seperated into two major groups : mutually exclusive and concomittent behaviors. The mutually exclusive behaviors included coding cathegories for 6. body motions assumed by the subjects during the observation session. These 6 standardized motions consisted of sitting from standing first, and serially tying down, reclining, sitting again, and then standing, 6 steps walking. Concomittent behaviors consisted of 12 observable patterns that can be observed systematically from the face, grimacing, bracing, rubbing, walking with arms fixed, support with hands on sitting or standing, guarded movement, limping, unbalaced weightbearing, stopped movement from tying position to sitting, sighing and graoning. Subjects were videotrecorded as they performed a 6-standardized sequence of motions, simultanously researcher measured the time spent performing each motion and step length. Patients were asked torate their subjective pain score on the 10 mm graphic rating scale ranging from 'no pain' to 'sever pain'. For scoring of the pain behaviors, two trained nursing officiers independently and simutanously viewwd each videorecording and checked subject 'pain behaviors at the observational item checklist. The result of the study are summarized as follows : 1. Reability of the observational tool was a=.845. 2. Spearman's rho and percentage agreement were p=.97 and 81.7 persent respectively, that indicate adequate interrater reability of this tool. 3. The sensitivity rate of the tool was .875 while specificity rate .866 for differentiating patient from the normal. 4. When difference in the objective pain indices between patient group and control were compared, there was significant difference of all indices, such as pain behavior(t=7.71, p=.0001). spent time performing motion(t=14.2, p=.0001), step length (t=-10.72, p=.0001). 5. There were differences in the objective indices the subjective pain subgroups (low, medium, high). Differences in the mean score of objective pain behavior (F=6.376. p=.005) and spent time for moyion(F=4.631, p=.018). But there were no significant differences in the step length among the subgroups(F=.667, p=.521). 6. Highly correlated pain behavior items wiyh subjective pain score were 'stopped movement from lying position to sitting', 'limping', 'support with hands on sitting or standing', 'bracing', 'guarding' and 'walking with arms fixed'. In summary, although some of rho behavior items such as sighing and groaning in this study could not be observed because of videotaped datd, the reliability and validity of the over all observation method were satifactory. Thus, the results of the present study demonstrate rye potetional utility of the tool in assessing objective pain complementing self-reported pain in low back pain patients.

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A Review on the Financial Profile of Profitability for the KOSDAQ Listed Firms Headquartered in 'Chungcheong' province in the Republic of Korea (국내 충청권 기반 KOSDAQ 상장기업들의 수익성 결정요인 분석)

  • Kim, Hanjoon
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.14 no.11
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    • pp.5476-5487
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    • 2013
  • From foreign and/or domestic investors' perspectives, it may be interesting to find any financial attributes or profile of the firms headquartered in 'Chungcheong' province concerning profitability, given that this subject so far drew less attention in the previous literature. This study performed three hypothesis tests on the profitability indicator by utilizing the models such as the 'panel data' one and the 'logistic' regression one, applying a modified 'Dupont' system. With respect to the major findings, the results identified that the proxies measuring leverage across the book-value(BVLEV1) and the market-value(MVLEV1) bases, were statistically significant constituents determining profitability. Another explanatory variable, SIZE, with its positive and statistically significant relationship to the indicator, represented that the firms in the province were smaller than their counterparts in the other regional areas in Korea. DRELY applying a modified 'Dupont' system, found to be the only statistically significant discriminating factor between these comparison groups. As one of the primary contributions of this study, the outcomes may be used by the financial institutions operated across the regions including Seoul Metropolitan area, when implementing their lending practices to provide funds for potential borrowers such as the firms belonging to 'Chungcheong' province.

Analysis of Undergraduate's Leadership through the Servant Leadership Curriculum (Focusing on the factors of professors, academic performance, friendship, and department) (섬김의 리더십 교육과정을 통한 대학생 리더십 분석 (교수, 학업성적, 교우관계, 학과 요인 중심으로))

  • Han, Man-Oh
    • Journal of Convergence for Information Technology
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    • v.10 no.2
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    • pp.109-115
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    • 2020
  • This study is for analyzing and verifying of impact and effect for undergraduate's leadership through the Servant Leadership curriculum. The Servant Leadership's lecture and period for this study has been done for 15th week, and 2 hours for each week. To verify the effectiveness of the Servant Leadership, we've composed 2 different groups and compared the results of the preliminary inspection and post-test, then analyzed the differences of the preliminary inspection and post-test with focusing on the research hypothesis. Statistical treatment of this study made use of the statistical program SPSS/WIN 22.0, and the method of analysis was done with factor analysis for validity verification of each factor. We used Frequency analysis like frequency and percentage about the generalities of the subject. Looking at the investigation of this research, the overalls such as the University Facilities, curriculum, professor and a school report was higher after training than before training the general programs, On the other hand, friendship and major got lower after training than before, but appeared no significant difference in the statistics. The whole leadership has appeared as heighten after education than before, through the servant Leadership's lecture Empowerment and personality were appeared as heighten after education than before, and Similarly on Human relations.

Dietary Intakes and Serum Lipids and Iron Indices in Obese Children (비만아동의 영양섭취와 혈청 지질농도 및 철분영양지표)

  • Kim, Jin-Yi;Han, Young-Shin;Bae, Hyun-Sook;Ahn, Hong-Seok
    • Korean Journal of Community Nutrition
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    • v.11 no.5
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    • pp.575-586
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    • 2006
  • This study was performed to compare nutrient intakes, diet quality and serum indices (TG, Total cholesterol, LDL-cholesterol, HDL-cholesterol, RBC, Hb, Hct, Serum iron, ferritin, MCV) of obese and normal weight children. The subjects were 149 children living in the Seoul and Gyeonggi areas. Each subject was assigned to one of such as normal weight group ($15th{\le}BMI$ percentile < 85th, n = 82) or obese children ($85th{\le}BMI$ percentile, n = 67) according to their percentile of BMI by The Korean Pediatric Society. Data on dietary intakes, body composition and serum indices were obtained. Differences of all the above variables were assessed. Energy, carbohydrate, fat, cholesterol, total fatty acid, SFA, MUFA, PUFA, phosphate, potassium, zinc, vitamin $B_1$ and vitamin $B_6$ intakes of girls in the obese group were higher than those of the normal weight group (p<0.05). The intake of fiber was as insufficient as below 50% of KDRIs in both groups. Nutrient adequacy ratio of calcium, iron, phosphate, zinc and folate in obese boys were lower than those of normal weight boys (p<0.05). Energy intakes of grain and milk and dairy food in the obese girl group ($905.9{\pm}344.5kcal,\;210.9{\pm}166.4kcal$) were higher than those of normal weight girls ($671.2{\pm}360.7kcal,\;184.0{\pm}103.5kcal$) (p<0.05). HDL-cholesterol level of obese boys ($52.7{\pm}6.3mg/dL$) was significantly lower than that of normal weight boys ($65.3{\pm}15.6mg/dL$). Serum iron level of obese boys and girls (boys: $79.4{\pm}32.6mg/dL$, girls: $98.3{\pm}16.2mg/dL$) was significantly lower than those of normal weight children (boys: $104.8{\pm}38.6mg/dL$, girls: $106.7{\pm}28.9mg/dL$) (p<0.05). These results suggest that there should be sensible food selection and more intakes of fruit and vegetable are needed to improve the nutritional status in obese children.

The Comparison of Effective of Stretching Exercise and Stabilizing Exercise for The Patients with Myofascial Pain Syndrome at The Shoulder Girdle (견관절부 근막동통증후군의 근육내 전기자극치료시 신장운동과 안정화운동의 효과 비교)

  • Kim, Sang-Eun;Lee, Hyun-Ok;Kim, Jong-Soon;Kim, Suhn-Yeop
    • The Journal of Korean Academy of Orthopedic Manual Physical Therapy
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    • v.11 no.2
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    • pp.49-61
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    • 2005
  • Summary of Background Data: Myofascial pain syndrome (MPS) is a common painful muscle disorder caused by trigger points occurring in myofascial. MPS is a major cause of chronical pain and is the subject of further clinical examination. Purpose: To uncover effective intramuscular stimulation therapy (IMS), the patients' actively participation stretching exercise and stabilizing around shoulder girdle where trigger point provoking myofascial pain syndrome in usually occurred. Methods: 45 myofascial pain syndrome patients were randomly chosen and divided into 3 groups. The first group (G1) received only IMS therapy, The second group (G2) had both IMS and active stretching exercises administered and the final group (G3) was given IMS therapy and stabilizing exercises. Therapy intervention was given for 3 weeks, 3 times a week and then only stretching exercise for the second group and stabilizing exercise for the third group was given for another 3 weeks. The visual analogue scale was dine before the experiment, 3 weeks after the experiment and 6weeks after the experiment to measure subjective degrees of pain and pressure pain threshold to measure sensitivity improvement of trigger point and functional ability questionnaire to measure daily life performance. Results: There were no significant changes after 3 weeks but after 6 weeks, between GI and G2 and between G1 and G3 showed significant change of pain, pressure pain threshold and daily life performance. There were significant improvement of the measurement of degrees of pain, pressure pain threshold and improvement of daily life performance at different times for G1 showed change 3 weeks after the experiment, but there were no changes 6 weeks after the experiment. There were significant improvement of the measurement at different times for G2 and G3 showed change 3 weeks after the experiment and 6 weeks after the experiment. Conclusions: IMS therapy proved to be effective in inactivation of trigger points of the myofascial pain syndrome patients and stretching and stabilizing exercises beside it keep remedial value longer by improvement of pain and dysfunction that occurred by the trigger point.

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Influence of Burnout and Coping Type on Organizational Citizenship Behavior among Employees at Korean Red Cross Blood Center (소진 및 대처 유형이 조직시민행동에 미치는 영향 - 적십자 혈액원 직원을 대상으로 -)

  • Kim, Young-Mi;Lee, Key-Hyo;Kim, Won-Joong;Park, Young-Seok
    • Korea Journal of Hospital Management
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    • v.9 no.4
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    • pp.87-100
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    • 2004
  • The main objective of this paper is to investigate the burnout state, coping types, and their relationship with organizational citizenship behavior, and based on the investigation, to provide some reference materials for effective management of burnout and appropriate methods of coping. For this purpose, employees of Korean Red Cross Blood Center were selected as the subject of the research. Data for empirical analysis were obtained through mail survey using structured and self-administered questionnaire for 282 employees of five Red Cross Blood Centers across the nation. Following is the summary of the results: 1) Degree of organizational citizenship behavior was higher among the married, the forties in age, and the employees whose major reason for choosing to work at the Center was 'to help other people.' On the other hand, degree of burnout was higher among the single but lower among the forties in age and the employees who chose to work at the Center because of suitable abilities and interests. As for the types of coping, problem-oriented coping method was more frequently used by the married, older, relatively more-educated and higher-grade employees. 2) Among the three kinds of burnout, 'achievement burnout' was found to have the greatest influence on the organizational citizenship behavior, negatively affecting organizational citizenship behavior as a whole and all of its components except for 'sportsmanship.' Next was 'impersonality burnout,' which also had negative effect on organizational citizenship behavior as a whole, and altruism, conscientiousness and sportsmanship among the components. Finally, 'emotion burnout' appeared to have positive effect on altruism and courtesy but negative effect on sportsmanship. 3) Among the various types of coping, 'problem-oriented' and 'positive perspective' coping methods were found to positively influence overall organizational citizenship behavior, whereas 'stress dissolution' had negative effect. These results imply that special management, counselling and education are needed for sociodemographic groups with high burnout to utilize problem-oriented and positive perspective coping methods which are considered to have desirable effects in coping with burnout problems. In addition, some methods should be devised to prevent and manage the 'achievement burnout' that was found to have great negative influence on organizational citizenship behavior.

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An Analysis of Korean Mathematics Teacher's Multicultural Competence: Implications for Multicultural Mathematics Teacher Education (우리나라 수학교사의 다문화역량 실태 연구 : 다문화수학교사교육 방안 탐색을 위한 제언)

  • Song, Ryoon-Jin;Noh, Sun-Sook;Ju, Mi-Kyung
    • Journal of Educational Research in Mathematics
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    • v.23 no.3
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    • pp.313-333
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    • 2013
  • In this research, the researchers constructed a survey questionnaire for measuring the multicultural competence of Korean mathematics teachers and administered the survey to 309 mathematics teachers. The analysis indicates that Korean mathematics teachers' level of multicultural competence is rather low (the mean is 2.636 and the standard deviation .290). In particular, the mean of the multicultural competence related to mathematics was lower than the mean of the multicultural competence in general. Moreover, there was no significant difference between the groups according to the length of teaching experience, the participation into the course in multicultural teacher education, and the experience of indirect exposure to people of different cultural background. On the contrary, the experience of direct exposure to people of different cultural background and teachers' major led to a significant difference in the within group comparison. Moreover, the analysis showed that mathematics teachers' level of competence in subject matter had significant impact on their teaching practice responsive to students' backgrounds. Based on the results, the researchers presented implications for the development of multicultural mathematics teacher education to enhance mathematics teachers' competence required for their teaching in culturally diverse school.

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