• Anxiety and mood
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• v.10 no.2
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• pp.143-150
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• 2014

Objective : The subgenual cingulate cortex, a part of default-mode network, has been known to playa key role in the pathophysiology of depression. The previous studies have reported abnormal functional connectivity between the subgenual cingulate cortex and other brain regions in the patients with depression. The goal of this shldy was to explore the resting-state functional connectivity of the subgenual cingulate cortex between the patients with depression and healthy subjects. Methods : Twenty patients with major depression and age- and sex-matched 20 healthy subjects underwent 5-minute resting state fMRI scans. The functional connectivity map in each subject was acquired using seed-based correlation analysis with the seed located in the subgenual cingulate cortex (Talairach coordinates; x=-10, y=5, z=-10). The functional connectivity maps were calculated using AFNI and compared between the patient and healthy subject group via two-sample T-test using 3dttest++ in AFNI package. Results : Functional connectivity was decreased between the subgenual cingulate cortex and both sides of fusiform gyrus in depressed subjects. Connectivity was also decreased between the subgenual cingulate cortex and the left cerebellum in the patient group. There was no correlation between the severity of depression and the degree of functional connectivity between the subgenual cingulate cortex and the regions showing decreased functional connectivity. Conclusion : Decreased resting-state functional connectivity between the subgenual cingulate cortex and both sides of fusiform gyrus, and decreased connectivity between the subgenual cingulate cortex and the left cerebellum found in the patients with major depression in comparison to the healthy subjects might be related to abnormal emotional and cognitive processing of depressed patients.

• Korean Journal of Child Studies
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• v.31 no.4
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• pp.1-14
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• 2010

The purpose of this study was to investigate the relationship between depression, colleagues/ supervisor's emotional support and burnout experienced by teachers in kindergartens and childcare centers. The subjects were 195 teachers who worked in kindergartens or childcare centers in Daegu and Gyeongbuk Province. Questionnaires, which required self-report by teachers, were used to investigate depression, colleagues/supervisor's emotional support and burnout. The data collected were analyzed by means of paired t-test, Pearson's correlation, simple regression, hierarchial regression, using SPSS Win 15.0. The results are as follows. (1) The emotional support from colleagues was significantly higher than from that provided by the supervisor. Moreover, teachers' depression levels were positively associated with burnout. (2) Colleagues' emotional support operated as major determining factor with the effect that burnout decreased as colleagues' emotional support levels increased. There were observable interactional effects between depression and the emotional support provided by colleagues' to colleagues experiencing burnout. (3) The supervisor's emotional support operated as a major factor with the effect that burnout decreased with a rise in the levels of a supervisor's emotional support. No interactional effects were observed between depression and supervisor's emotional to colleagues dealing with burnout.

• Journal of Korean Public Health Nursing
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• v.19 no.2
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• pp.305-315
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• 2005

Purpose: The purpose of this study was to investigate the relationships among depression, sleep patterns and health promoting behavior in female college students. Methods: The subjects of this study consisted of 350 college students. The data was collected through self-administered questionnaires from November to December of 2004. The data was analyzed via the SPSS computer program by using descriptive statistics, t-tests, ANOVA and Pearson's correlation coefficients. Results: There are significant differences and impacts on depression according to the amount of coffee consumed, the time spent on computer and the amount of smoke inhaled. Sleep patterns differ depending on one's college major, the time spent on computer, and the amount of smoke inhaled. Health promotion behavior was shown to be significantly different according to the living style, college major and how much TV was watched The mean scores for depression, sleep patterns, health promoting behavior were 1.45 (on a 3 points scale), 2.71 (on a 4 points scale), and 3.03 (on a 5 point scale), respectively. There was a significant positive correlation between sleep patterns and health promoting behavior, and there was negative correlation between depression and health promoting behavior, and between depression and sleep patterns in college students. Conclusion: The findings of this study give useful information to create further studies on intervention programs related to health promoting behavior for college female students.

• Journal of Nutrition and Health
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• v.54 no.2
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• pp.152-164
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• 2021

Purpose: This study aimed to examine the association between depression and eating behavior factors in Korean adults. Methods: Study subjects were selected (n = 5,103) from the participants of the 7th Korea National Health and Nutrition Examination Survey 2018 and divided into depression (men, 59; women, 162) and normal groups (men, 2,083; women, 2,799). Subjects with a Patient Health Questionnaire 9 score ≥ 10 (out of 27 points) were defined as having depression. Results: A higher prevalence of depression was observed in both men and women who were unemployed (p < 0.001, p = 0.008), had lower income (both p < 0.001), poorer subjective health (both p < 0.001), and poor food safety (both p < 0.001). The prevalence of depression was higher in women with lower education levels (p = 0.008), who were unmarried (p = 0.010), smokers (p < 0.001), and in a one-person household (p = 0.001). Obese men showed a higher prevalence of depression (p = 0.009). Men who were eating alone or skipping lunch had a high prevalence of depression (p = 0.009), while women who were eating breakfast (p = 0.012), lunch (p = 0.001), and dinner (p = 0.010) alone had a high prevalence of depression. The relationship analysis between men and women according to dietary habits using logistic regression showed that, in women, after variable adjustment, skipping lunch (odds ratio [OR], 2.677; 95% confidence interval [CI], 1.090-6.574), meal frequency of 2 times per day (OR, 1.658; 95% CI, 1.084-2.536), and lunch frequency of 3-4 times per week (OR, 3.143; 95% CI, 1.725-5.728) were significantly associated with a higher prevalence of depression. Conclusion: Depression in women was not only affected by more sociodemographic variables but also associated with decreased frequency of lunch and dinner, especially with skipping lunch.

• Mood & Emotion
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• v.9 no.2
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• pp.57-63
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• 2011

Objectives : This study aimed to investigate the prevalence and risk factors of depression within two weeks after stroke. Methods : A total of 362 stroke patients were recruited. Depression (major and minor depressive disorders) was diagnosed by applying DSM-IV criteria. Data on socio-demographic characteristics (age, gender, education, marital state, living state, religion, occupation, income, life event, and social support), stroke severity (NIHSS), disability (BI), stroke hemisphere and location, vascular risk and disease, and previous history of stroke and depression were obtained. Results : Depression was present in 90 (24.9%) patients: major depression 29 (8%) and minor depression 61 (16.9%) patients. In the univariate analyses, depression was associated with older age, higher number of stressful life event, poorer social support, severe disability, anterior stroke location, previous history of stroke and depression. In the multivariate analyses, depression was independently associated with higher number of stressful life events and poorer social support. Conclusion : Depression was common and was determined by premorbid levels of stress and social support in stroke patients at acute stage. More intensive psychiatric care and intervention is needed for the high risk group.

• Journal of Korean Academy of Rural Health Nursing
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• v.6 no.2
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• pp.69-77
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• 2011

Purpose: This study was done to identify the current status of research on depression in married immigrant women and to suggest directions for future nursing research. Method: Sixteen articles for the period between 2001 and 2010 were selected by key words such as "Married Immigrant Women" and "Depression" from the databases (RISS4U et al). Results: Twelve of the research reports were related to correlations and 4 were related to interventions. Depression level was measured using BDI or CES-D. Depression levels were as follows: 20-30% reported major depression and less than 10%, severe depression. Factors which influenced depression included: socio-demographic factors, and family, economic, psychological and situational characteristics. Psychological treatment prevailed in the intervention research, for example, art therapy, and horticultural therapy. In 2 papers significant improvement in the state of depression among participants in the intervention group were reported. Conclusion: The next phase of nursing research related to married immigrant women is to reconsider the importance of the concept of depression to reexamine research methods and directions.

• Korean Journal of Biological Psychiatry
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• v.13 no.1
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• pp.11-18
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• 2006

Depressive disorder is one of well-known major public health problems in Korea. The socioeconomic burden of depression is growing bigger and bigger. Therefore, the Korean government decided to establish the clinical research center for depression for better care of patients with depression. One of the major task of the center is the development of Korean clinical practice guideline for depressive disorders. This guideline should reflect the clinical situation in Korea and meet Korean physicians' needs. In addition, it should be feasible and easy to use. We reviewed the present status of the guideline development in Korea and other countries, and introduces the scope, method, and goals of Korean clinical practice guideline for depression.

• Bioinformatics and Biosystems
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• v.1 no.2
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• pp.134-138
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• 2006

Depression is the most common and widespread mood disorder. About 20% of the population might suffer a major, incapacitating episode of depression during their lifetime. This disorder can be classified into two types: major depressive disorders and bipolar disorder. Since pharmaceutical treatments are different according to types of depression disorders, correct and fast classification is quite critical for depression patients. Yet, classical statistical method, such as minnesota multiphasic personality inventory (MMPI), have some difficulties in applying to depression patients, because the patients suffer from concentration. We used electroencephalogram (EEG) analysis method fer classification of depression. We extracted nonlinearity of information flows between channels and estimated approximate entropy (ApEn) for the EEG at each channel. Using these attributes, we applied two types of data mining classification methods: decision tree and possibilistic support vector machines (PSVM). We found that decision tree showed 85.19% accuracy and PSVM exhibited 77.78% accuracy for classification of depression, 30 patients with major depressive disorder and 24 patients having bipolar disorder.

• Journal of Oriental Neuropsychiatry
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• v.34 no.4
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• pp.453-461
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• 2023

Objectives: Major depressive disorder is a severe disease that is associated with suicidal ideation and behavior. In this case, Korean medicine psychotherapy and Korean medicine treatment were used to treat an adolescent patient with major depressive disorder. Methods: The Beck Depression Inventory, Reynolds Suicidal Ideation Questionnaire, and Crisis Triage Rating Scale were used as psychological evaluation scales. Korean medicine psychotherapy focuses on Giungoroen-therapy and IiGyeungByunQi-therapy and Korean medicine treatment combined with acupuncture, moxa, and herbal medicine. Results: Comparison before and after treatment showed improvement in clinical symptoms, Beck Depression Inventory, Reynolds Suicidal Ideation Questionnaire, and Crisis Triage Rating Scale. Conclusions: As a result of applying Korean medicine, psychotherapy and Korean medicine treatment reduces to an adolescent patient with major depressive disorder, depression, suicidal thoughts, and suicidal behavior.

• Journal of Oriental Neuropsychiatry
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• v.33 no.4
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• pp.389-400
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• 2022

Objectives: Depression is a highly prevalent disease, and the market for antidepressant drugs continues to grow at a steady rate. Although current antidepressants are reported to be effective, because of their low remission rate and side effects, new antidepressants are needed. The use of Banhahubak-tang (BHT) to treat the symptoms of depression is supported by experimental evidence. The proposed study will evaluate the efficacy and safety of BHT in treating depression. Methods: A randomized, waitlist-controlled, parallel clinical trial will be conducted to assess the efficacy of BHT in depression. A total of 84 participants with depression will be randomized into the intervention group or waitlist-control group at a 1:1 ratio. Patients in the intervention group will be administered BHT three times a day for four weeks and followed up for four more weeks after therapy completion. Patients in the waitlist-control group will undergo the same intervention and follow-up after a four-week waiting period. The primary outcome is change in the Korean version of the Hamilton Depression Rating Scale (K-HDRS) scores for major depressive disorders after four weeks. The secondary outcomes include scores on the K-HDRS, Korean Symptom Check List 95 (KSCL-95), Insomnia Severity Index (ISI), State-Trait Anxiety Inventory-Korean version (STAI-K), State-Trait Anger Expression Inventory-Korean version (STAXI-K), and the Instrument on Pattern Identifications for Depression and EuroQol-5 Dimension (EQ-5D). Conclusions: This trial will provide high-quality clinical evidence of the efficacy and safety of BHT in the management of depression.