• Journal of the Korean Society for information Management
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• v.35 no.4
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• pp.141-164
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• 2018

Recently, as the amount of academic literature has increased rapidly and complex researches have been actively conducted, researchers have difficulty in analyzing trends in previous research. In order to solve this problem, it is necessary to classify information in units of academic papers. However, in Korea, there is no academic database in which such information is provided. In this paper, we propose an automatic classification system that can classify domestic academic literature into multiple classes. To this end, first, academic documents in the technical science field described in Korean were collected and mapped according to class 600 of the DDC by using K-Means clustering technique to construct a learning set capable of multiple classification. As a result of the construction of the training set, 63,915 documents in the Korean technical science field were established except for the values in which metadata does not exist. Using this training set, we implemented and learned the automatic classification engine of academic documents based on deep learning. Experimental results obtained by hand-built experimental set-up showed 78.32% accuracy and 72.45% F1 performance for multiple classification.

• Journal of Korean Physical Therapy Science
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• v.26 no.1
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• pp.22-34
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• 2019

Purpose: The purpose of this study was to investigate the effects of body blade and Thera band exercise on upper extremity strength, grip strength and balance of university students. Design: Single Blind Randomized Controlled Trial. Method: twenty healthy adults, participated in this study, and were recruited by G University in Gimcheon Korea. The subjects were randomly divided into A group that went through Thera band exercise and B group that went through Body blade exercise. Each group had 10 subjects. All subjects did the experiment for 3 times a week for 3weeks. Spss was used for statistical analysis. Result: 1) Grip strength: After exercising, for the BE group, there were statistically significant differences in dominant and non-dominant hand. However, for the TE group, there were no significant statistical differences in both hands. 2) muscle strength: In the TE group there were no significant statistical differences in the dominant and non-dominant arm. But in the BE group there were differences which were found. 3) balance: After exercising, both groups had no significant statistical difference in medial lateral balance. In anterior and posterior balance, TE group had no statistical significant difference but BE group did. Conclusion: To improve muscle strength balance and grip strength, body blade exercise is more effective than Thera band exercise.

• Journal of the Korean Society of Fisheries and Ocean Technology
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• v.55 no.3
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• pp.217-232
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• 2019

It was turned out by shrimp beam trawl monthly survey from March, 2015 to February, 2016 that different species composition and abundance of the fish assemblages in Sacheon Bay and coastal waters off Namhae, Korea were compared. As a result of monthly measured sea temperature and salinity of Sacheon Bay and coastal waters off Namhae, sea temperature of both areas was changed seasonally; however, differences in sea temperature occurred during certain periods depending on the region. Salinity was generally low in Sacheon Bay affected by fresh water, and both areas was low in summer and high in winter. A total of 73 species representing 37 families were collected in Sacheon Bay. The dominant fish species in terms of numbers and biomass were Liparis tanakae, $23,077inds./km^2$, $332.1kg/km^2$. A total of 91 fish species representing 49 families were collected in coastal waters off Namhae. The dominant fish species in terms of numbers were Leiognathus nuchalis, $139,683inds./km^2$ and biomass were Chelidonichthys spinosus, $1,078.6kg/km^2$. Analysis of dendrogram of the clustering showed that Sacheon Bay and coastal waters off Namhae were distinctive featured (global R = 0.691, p = 0.017). And except of summer season (July-October), there was a distinctive feature seasonally (global R = 0.844, p = 0.001). The fish species that appeared in common in both areas, where fish species caught in Sacheon Bay, an important inner bay,were smaller than those caught in coastal waters off Namhae appeared. It presented that Sacheon Bay plays a more important role in spawning and nursery ground for fisheries resource than coastal waters off Namhae, Korea.

• The Journal of the Korean dental association
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• v.57 no.10
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• pp.560-568
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• 2019

Purpose: This study evaluated the antibacterial effects of curcuma, ginger, and finger root extracts in water-soluble powder on planktonic Streptococcus mutans(S.mutans), which is known to cause dental caries, in order to confirm whether these extracts could perform as photosensitizers for the effects of photodynamic therapy (PDT). Methods: This study used the strain of streptococcus mutans ATCC 25175 distributed by the Korean Collection for Type Cultures of the Korea Research Institute of Bioscience & Biotechnology. Commercial edible curcuma, ginger and finger root were used as the natural extracts for the use of photosensitizer. To extract organic solvent, 3 g of each powder was mixed in $30m{\ell}$ of dimethyl sulfoxide (DMSO, VWR, Germany) before extraction. $1.8m{\ell}$ of the photosensitizer solution, manufactured in the concentrations of 5, 0.5, and $0.05mg/m{\ell}$, was mixed with $0.2m{\ell}$ of the S. mutans culture medium that had been cultured for 2 days. To induce the photodynamic reaction, Qraycam (AIOBIO, Seoul, Korea) equipped with 405 nm LED was used to expose light for 5 minutes to irradiate 59 nW energy for 300 seconds. Results: Compared with the case with no light, a higher photodynamic therapeutic effect was confirmed with $0.05mg/m{\ell}$ curcuma powder extract, the concentration of $0.5mg/m{\ell}$ and LED light of 405 nm wavelength (p=0.000, p=0.003). $0.05mg/m{\ell}$ of curcuma powder extract and the concentration of $0.5mg/m{\ell}$ showed 100% antibacterial effect when exposed to light, whereas the concentration of $5mg/m{\ell}$ showed 11.95% antibacterial effect. When exposed to light, $0.05mg/m{\ell}$ of ginger powder extract showed an antibacterial effect which didn't statistically decrease. The concentrations of $0.5mg/m{\ell}$ and $5mg/m{\ell}$ did not show any antibacterial effects. As a result of examining any photodynamic therapeutic effects of finger root powder extract on S. mutans, no statistically significant effect was found. Conclusion: The curcuma powder extract is expected to perform as a photosensitizer. Even though belonging to the same ginger family, ginger powder and finger root powder seem difficult to perform as photosensitizer.

• Molecules and Cells
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• v.42 no.6
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• pp.480-494
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• 2019

Aggregates of disease-causing proteins dysregulate cellular functions, thereby causing neuronal cell loss in diverse neurodegenerative diseases. Although many in vitro or in vivo studies of protein aggregate inhibitors have been performed, a therapeutic strategy to control aggregate toxicity has not been earnestly pursued, partly due to the limitations of available aggregate models. In this study, we established a tetracycline (Tet)-inducible nuclear aggregate (${\beta}23$) expression model to screen potential lead compounds inhibiting ${\beta}23$-induced toxicity. High-throughput screening identified several natural compounds as nuclear ${\beta}23$ inhibitors, including peucedanocoumarin III (PCIII). Interestingly, PCIII accelerates disaggregation and proteasomal clearance of both nuclear and cytosolic ${\beta}23$ aggregates and protects SH-SY5Y cells from toxicity induced by ${\beta}23$ expression. Of translational relevance, PCIII disassembled fibrils and enhanced clearance of cytosolic and nuclear protein aggregates in cellular models of huntingtin and ${\alpha}$-synuclein aggregation. Moreover, cellular toxicity was diminished with PCIII treatment for polyglutamine (PolyQ)-huntingtin expression and ${\alpha}$-synuclein expression in conjunction with 6-hydroxydopamine (6-OHDA) treatment. Importantly, PCIII not only inhibited ${\alpha}$-synuclein aggregation but also disaggregated preformed ${\alpha}$-synuclein fibrils in vitro. Taken together, our results suggest that a Tet-Off ${\beta}23$ cell model could serve as a robust platform for screening effective lead compounds inhibiting nuclear or cytosolic protein aggregates. Brain-permeable PCIII or its derivatives could be beneficial for eliminating established protein aggregates.

• Journal of Internet Computing and Services
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• v.22 no.2
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• pp.1-9
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• 2021

Traditionally, most malicious codes have been analyzed using feature information extracted by domain experts. However, this feature-based analysis method depends on the analyst's capabilities and has limitations in detecting variant malicious codes that have modified existing malicious codes. In this study, we propose a ResNet-Variational AutoEncder-based variant malware classification method that can classify a family of variant malware without domain expert intervention. The Variational AutoEncoder network has the characteristics of creating new data within a normal distribution and understanding the characteristics of the data well in the learning process of training data provided as input values. In this study, important features of malicious code could be extracted by extracting latent variables in the learning process of Variational AutoEncoder. In addition, transfer learning was performed to better learn the characteristics of the training data and increase the efficiency of learning. The learning parameters of the ResNet-152 model pre-trained with the ImageNet Dataset were transferred to the learning parameters of the Encoder Network. The ResNet-Variational AutoEncoder that performed transfer learning showed higher performance than the existing Variational AutoEncoder and provided learning efficiency. Meanwhile, an ensemble model, Stacking Classifier, was used as a method for classifying variant malicious codes. As a result of learning the Stacking Classifier based on the characteristic data of the variant malware extracted by the Encoder Network of the ResNet-VAE model, an accuracy of 98.66% and an F1-Score of 98.68 were obtained.

• The Journal of Korean Medicine Ophthalmology and Otolaryngology and Dermatology
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• v.34 no.4
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• pp.1-11
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• 2021

Objectives : The aim of this study was to investigated the anti-aging and anti-wrinkles effects of the pinus koreaiensis seed(PKS) oil. Methods : The anti-oxidant effect was performed by beta-carotene bleaching assay and the intracellular proteome was analyzed expression of each 15 proteins by 2-D electrophoresis. And fatty acid was analysed by gas chromatography. Anti-wrinkle effect was analyzing human skin by the PRIMOS system. Results : Fatty acid analysis of PKS oil has shown oleic acid was 49.7% and linoleic acid was 34.1%. And the antioxidant effect was about 125% compared with alpha-tocoperol(0.1%) by beta carotene bleaching assay. In 2D PAGE analysis, fifteen protein changes in five mechanisms which was collagen synthesis pathway, MMPs, ECM-cell interaction, cytokine, antioxidant enzymes were analyzed. In case of anti-wrinkle effect was proved in vivo by analyzing human skin by the PRIMOS system. The analysis results of eye wrinkles for 4 weeks showed an improvement effect of over 6%. Conclusions : In this study, the amount of protein change in the five mechanism through the cell experiment and the skin anti wrinkle efficacy by the human in vivo test were investigated. As a result pinus koreaiensis seed oil by supercritical extraction could be used as a anti-aging and anti-wrinkle substance for the skin.

• Korean Journal of Optics and Photonics
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• v.32 no.5
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• pp.209-214
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• 2021

High-power continuous-wave operation of a Yb-doped double-clad fiber laser at 1018 nm, pumped by high-power diode lasers at 976 nm, is reported. Based on numerical calculation of the gain and laser signal power along the length of the Yb fiber, it is found that robust operation at 1018 nm can be achieved for a high Yb³⁺-ion excitation density greater than 11.5%, accompanied by high suppression of the feedback from the fiber's end facet. The Yb fiber laser constructed in house yields 626 W of continuous-wave output at 1018 nm for 729 W of incident pump power, corresponding to a slope efficiency of 86.6%. The prospect for power scaling is considered.

• Journal of Internet Computing and Services
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• v.22 no.4
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• pp.1-11
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• 2021

As the Internet developed, various and complex cyber attacks began to emerge. Various detection systems were used outside the network to defend against attacks, but systems and studies to detect attackers inside were remarkably rare, causing great problems because they could not detect attackers inside. To solve this problem, studies on the lateral movement detection system that tracks and detects the attacker's movements have begun to emerge. Especially, the method of using the Remote Desktop Protocol (RDP) is simple but shows very good results. Nevertheless, previous studies did not consider the effects and relationships of each logon host itself, and the features presented also provided very low results in some models. There was also a problem that the model could not explain why it predicts that way, which resulted in reliability and robustness problems of the model. To address this problem, this study proposes an interpretable RDP-based lateral movement detection system using page rank algorithm and SHAP(Shapley Additive Explanations). Using page rank algorithms and various statistical techniques, we create features that can be used in various models and we provide explanations for model prediction using SHAP. In this study, we generated features that show higher performance in most models than previous studies and explained them using SHAP.

• Korean Journal of Remote Sensing
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• v.37 no.3
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• pp.627-636
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• 2021

Although many studies on ship detection using synthetic aperture radar (SAR) satellite images are being conducted around the world, there are still very few employing SAR microsatellites, as most of the microsatellites are optical satellites. Recently, the ICEYE and Capella Space have embarked on the development of microsatellites with SAR sensor, and similar projects are being initiated globally in line with the flow of the new space era [e.g., for the ICEYE: 18 satellites (~2021); Capella Space: 36 satellites (~2023); and the Coast Guard SAR: 32 satellites in the early development stage]. In preparation for these new systems, it is important to review the SAR microsatellite system and the recent advances in this technology. Accordingly, in this paper, the current status and characteristics of optical and SAR microsatellite constellation operation are described, and studies using them are investigated. In addition, based on the status and characteristics of the representative SAR microsatellites, specifically the ICEYE and Capella systems, methods for using SAR microsatellite data for ship detection applications are described. Our results confirm that the SAR microsatellites operate as a constellation and have the advantages of short revisit cycles and quick provision of high-resolution images. With this technology, we expect SAR microsatellites to contribute greatly to the monitoring a wide-area target vessel, in which the spatiotemporal resolution of the imagery is especially important.