• Title/Summary/Keyword: MIGRATION

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Water Extracts of Aralia elata Root Bark Enhances Migration and Matrix Metalloproteinases Secretion in Porcine Coronary Artery Endothelial Cells

  • Oh, In-Suk;Han, Ji-Won;Kim, Hwan-Gyu
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.10 no.4
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    • pp.372-377
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    • 2005
  • Aralia elata is an edible mountain vegetable. Angiogenesis, the formation of new blood vessels, is a process involving migration, proliferation and cell differentiation, as well as the formation of new capillary structures. Matrix metalloproteinases (MMPs) plays an important role in angiogenesis. The development of a functional vascular system requires a variety of growth factors, their receptors, and intracellular signals. This study examines the effects of water extracts from: (i) A. elata root bark (Aralia extracts); (ii) a combination of Aralia extracts and fibroblast growth factors (FGF-2) on cultured porcine coronary artery endothelial cells (PCAECs). Aralia extracts induced the migration of PCAECs, which was inhibited by MMPs inhibitors. Combining Aralia extracts and FGF-2 enhanced the migration and the secretion of MMP-2 and MMP­9 from PCAECs. We postulated that the Aralia extracts, which induced migrating activity in PCAECs, may be accomplished by increased secretion levels of MMP-2 and MMP-9.

Chemotactic Cell Migration around Hollow Silica Beads Containing Chemotatic Reagent (약물 담지 다공성 중공 실리카 미세구 주위 세포의 주화성 이동)

  • Kim, Hae-Chun;Kang, Mi-Seon;Rhee, Seog-Woo
    • KSBB Journal
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    • v.25 no.4
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    • pp.344-350
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    • 2010
  • This paper demonstrates a microfluidic chip incorporating patterned hollow silica beads that can be effectively used for chemotaxis assay. The hollow silica bead has been exploited to develop a carrier for chemoattractant to induce cell migration. The microfluidic chip contains a patterned array of microfabricated docks which can hold only one bead per docking site. The hollow bead placed inside microfluidic chip releases chemotactic reagent (PDGF-BB) around its periphery in a controlled fashion which generates a signal for chemotatic migration of fibroblast cells. The number of cells migrated close to each bead has been assessed. On-chip cell migration assay showed a remarkable result proving the high efficiency and reliable accuracy in quantitative analysis. Therefore, the device could be extensively used in cell migration assay and other various studies related to cellular movements.

A Resource Oriented Live migration Algorithm for Removing Hotspot in Virtualized Clusters (가상화 클러스터를 위한 Hotspot 원인 정보 기반Live migration Algorithm)

  • Kang, Mun-Young;Oh, Sang-Yoon
    • Proceedings of the Korean Information Science Society Conference
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    • 2011.06b
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    • pp.9-12
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    • 2011
  • 가상화 기술은 물리적 컴퓨팅 자원의 추상화를 통해 다수의 운영 체제나 응용 프로그램이 물리적 서버의 자원을 공유하게 함으로써 소요비용을 절감하고 자원을 통합 관리할 수 있는 기술이다. 그러나 가상화 기반 클러스터에서는 클러스터를 이루는 물리적 서버들이 균형적으로 자원을 활용하지 못하고 특정 서버로 자원 활용률이 집중되는 현상(hotspot)이 발생 할 수 있다. 이에 본 논문에서는 Live migration 기술을 이용하여 가상화 클러스터의 자원 효율을 높이는 알고리즘을 제안한다. 제안 알고리즘은 hotspot의 원인이 되는 자원의 우선순위를 기반으로 가장 적합한 대상을 선정하여 가상머신을 이동시켜 클러스터의 자원 활용률의 균형을 도모하고 추가적인 hotspot의 발생을 최소화고 불필요한 Live migration을 방지하여 migration시에 발생하는 로드를 줄일 수 있다.

Improvement of Migration Fastness of Perfluorocarbons-free Synthetic Suede by Chitosan Pretreatment (키토산 전처리를 통한 과불화탄소 무함유 합성 스웨이드의 이염성 견뢰도 향상)

  • Lee, Hye Mi;Kim, Ah Rong;Kim, Dae Geun
    • Textile Coloration and Finishing
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    • v.31 no.4
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    • pp.258-267
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    • 2019
  • Synthetic suede without PFCs(perfluorinated compounds) are followed by subsequent high temperature treatment. But migration fastness of synthetic suede may be reduced due to sublimation of disperse dyes that results from the high temperature treatment. Therefore, in this study, chitosan treatment was used to improve the migration fastness before polyurethane dipping process. Polyester fiber was treated with sodium hydroxide aqueous solution before chitosan processing. This samples treated with a chitosan concentration upto 0.5% were dyed and coated with PUD(polyurethane dispersion). The migration fastness was most improved at 0.35% application. This is presumably due to the fact that the chitosan may increase the dye-binding capability through intermolecular hydrogen bonding.

The Distribution and Position of Fatty Acids in Glycerides Hydrolyzed from Fish Oil by Lipase

  • Hur, Byung-Ki;Hu, Hong-Bo;Yun, Hyun-Shik
    • Journal of Microbiology and Biotechnology
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    • v.10 no.4
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    • pp.502-506
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    • 2000
  • In order to determine the position and the content of fatty acids sttached to glycerides and the migration degree of fatty acids in the migration reaction, fish oil was hydroyzed with lipolase-100T which was derived from Aspergillus oryzae. The content of fatty acids in the glyceride mixture was analyzed and compared with that of fish oil. The amounts of fatty acid in a 2-position and the migration degree of the fatty acid in 2,3-DG (diglyceride) and 2-MG (monolyceride) were carefully calculated. The results showed that approximately 95% (w/w) of DHA (docosahexanoic acid) and 65% of EPA(eicosapentaenoic acid) were attached to the 2-position of glycerides in fish oil. Approximately 87% (w/w) of DHA and 75% of EPA remained in 2,3-DG, and 88% of DHA and 65% of EPA in 2-MG were not involved in the migration reaction.

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The Optimal Design of a Brushless DC Motor Using the Advanced Parallel Genetic Algorithm

  • Lee, Cheol-Gyun
    • Journal of the Korean Institute of Illuminating and Electrical Installation Engineers
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    • v.23 no.3
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    • pp.24-29
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    • 2009
  • In case of the optimization problems that have many design variables, the conventional genetic algorithms(GA) fall into a trap of local minima with high probability. This problem is called the premature convergence problem. To overcome it, the parallel genetic algorithms which adopt the migration mechanism have been suggested. But it is hard to determine the several parameters such as the migration size and the migration interval for the parallel GAs. Therefore, we propose a new method to determine the migration interval automatically in this paper. To verify its validity, it is applied to some traditional mathematical optimization problems and is compared with the conventional parallel GA. It is also applied to the optimal design of the brushless DC motor for an electric wheel chair which is a real world problem and has five design variables.

A Study on Migration Strategy for Long-term Preservation of Electronic Records (전자기록물 장기보존을 위한 마이그레이션 전략에 관한 연구)

  • Kwon, Do-Yun;Kim, Heesop;Oh, Sam-Gyun
    • Journal of Korean Society of Archives and Records Management
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    • v.9 no.2
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    • pp.19-40
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    • 2009
  • In this study, we proposed some fundamental considerations in application of a migration strategy for long-term preservation of electronic records. It also reviewed the notion of migration and various data migration strategies such as DPT and CAMiLEON through the literature survey.

Regulations of Food Packaging in Korea, Europe and USA (우리나라, 유럽 및 미국의 식품용 용기포장재 기준규격 관리제도 연구)

  • Jeon, Dae-Hoon;Lee, Young-Ja
    • KOREAN JOURNAL OF PACKAGING SCIENCE & TECHNOLOGY
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    • v.13 no.2
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    • pp.75-78
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    • 2007
  • Regulation of food packaging in Korea, Eurpoe and USA are surveyed. Food packaging manufacturer or converter has a responsibility to evaluate the safety of migration of harmful materials from typical finished packaging items. The 'overall migration limit' of all components from the packaging and 'specific migration limits(SML)' of monomers or additives are evaluated with food simulants, water, acetic acid, ethanol and n-heptane, based on the regulations of the countries. A substance not regulated has to be authorized with the technical data required, information on chemical identity, physical chemical and other properties, the intended use, migration studies and toxicological studies.

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Sildenafil Citrate Induces Migration of Mouse Aortic Endothelial Cells and Proteinase Secretion

  • Kim, Young-Il;Oh, In-Suk;Park, Seung-Moon;Kim, Hwan-Gyu
    • Biotechnology and Bioprocess Engineering:BBE
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    • v.11 no.5
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    • pp.402-407
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    • 2006
  • Vascular endothelial cells release proteinases that degrade the extracellular matrix (ECM), thus enabling cell migration during angiogenesis and vasculogenesis. Sildenafil citrate stimulates the nitric oxide-cyclic guanosine monophosphate pathway through inhibition of phosphodiesterase type V (PDE5). In this report, we examined the mechanisms underlying sildenafil citrate-induced cell migration using cultured mouse aortic endothelial cells (MAECs). Sildenafil citrate induced migration and proteinase secretion by murine endothelial cells. Sildenafil citrate induced the secretion of matrix metalloproteinase-2 (MMP-2) and MMP-9, which is inhibited by $NF-{\kappa}B$ inhibitors. Sildenafil citrate also induced the secretion of plasmin, which is inhibited by PI 3'-kinase inhibitors. It is suggested that sildenafil citrate-induced migrating activity in endothelial cells may be accomplished by increased secretion of proteinases.

Equifield line simulation and ion migration prediction for concrete under 2-D electric field

  • Liu, Chih-Chien;Kuo, Wen-Ten;Huang, Chun-Yao
    • Computers and Concrete
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    • v.12 no.4
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    • pp.431-442
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    • 2013
  • This study attempted to find a proper method applicable to simulating practical equifield lines of two-dimensional Accelerate Lithium Migration Technique (ALMT), and evaluate the feasibility of using the theoretical ion migration model of one-dimensional ALMT to predict the ion migration behavior of two-dimensional ALMT. The result showed that the electrolyte or carbon plate can be used as matrix to draw equifield line graph similar to that by using mortar as matrix. Using electrolyte electrode module for simulation has advantages of simple production, easy measurement, rapidness, and economy. The electrolyte module can be used to simulate the equifield line distribution diagram in practical two-dimensional electrode configuration firstly. Then, several equifield line zones were marked, and several subzones under one-dimensional ALMT were separated from various equifield line zones. The theoretical free content distribution of alkali in concrete under two-dimensional electric field effect could be obtained from duration analysis.