• BMB Reports
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• v.47 no.9
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• pp.524-529
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• 2014

Oxidative stress and inflammation are common to many pathological conditions. Defense mechanisms protect cells from oxidative stress, but can become over-activated following injury and inflammation. NF-${\kappa}B$ and Nrf2 transcription factors regulate proinflammatory and antioxidant gene expression, respectively. Studies have shown that many natural dietary compounds regulate NF-${\kappa}B$ and Nrf2, preventing inflammation and oxidative stress. Here, we report major compounds of Prunella vulgaris var. lilacina such as rosmarinic acid, oleanolic acid, ursolic acid and caffeic acid as a potential therapeutic for oxidative stress and inflammation. The major compounds exhibited high anti-inflammatory activity, inhibiting NO, PGE2 production, NF-${\kappa}B$ expression and activating Nrf2 expression. In addition, we examined the effect of major compounds on MafK expression. Among the compounds, oleanolic acid significantly decreased MafK expression and MafK-mediated p65 acetylation. These findings suggest that oleanolic acid as NF-${\kappa}B$ inhibitors can potentially be used in therapeutic applications for the treatment of oxidative stress-induced diseases.

• Proceedings of the Korean Society of Broadcast Engineers Conference
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• 2006.11a
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• pp.289-295
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• 2006

The Musical Slide Show MAF, which currently being standardized by MPEG, conveys the concept of combining several established standard technologies in a single file format. It defines the format of packing up MP3 audio data, along with MPEG-7 Simple Metadata Profile and MPEG-21 Digital Item Declaration metadata; with JPEC images and optional text, and synchronizes them all together to create a slideshow of JPEC image data associated to MP3 audio data during the audio playback. The implementation of Musical Slide Show MAF can be a music karaoke file where users can sing along while listening to the music, view the JPEG slideshow and reading the lyrics; or a story-telling file where users can listen to the narrated story by looking at the related illustration slideshow of the story In this paper we present the tool to producing the Musical Slide Show MAF contents. Regardless the knowledge of user on the MAF file format, the authoring tool simplify the manner of packaging several multimedia contents into single file.

• Proceedings of the IEEK Conference
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• 2005.11a
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• pp.967-970
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• 2005

The Music Player MAF Player Format of ISO/IEC 23000-2 FDIS consists of MP3 data, MPEG-7 metadata and one optional JPEG image data based on MPEG-4 File Format. However, the current Music Player MAF format does not allow multiple JPEG image data or timed text data. It is helpful to use timed text data and multiple JPEG images in the various multimedia applications. For example, listening material for the foreign language needs an additional book which has text and images, the audio contents which can get image and text data can be helpful to understand the whole story and situations well. In this paper, we propose the detailed file structure in conjunction with MPEG-4 File Format in order to improve the functionalities, which carry multiple image data and text data with synchronization information between MP3 data and other resources.

• Proceedings of the Korean Information Science Society Conference
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• 1999.10c
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• pp.715-717
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• 1999

인터넷 환경에서 분산 애플리케이션을 개발하는데 있어서 다양한 기술과 방법이 사용되고 있다. 그 중 이동에이전트를 이용하는 기술은 서버의 인터페이스를 바꾸지 않고 클라이언트의 다양한 요구를 융통성 있게 서비스할 수 있고, 네트웍 트래픽(traffic)을 줄이는 패러다임 특성 때문에 현재 널리 각광받고 있다. 하지만, 대부분의 이동 에이전트 시스템들은 그 구조와 구현이 매우 상이하여, 이동 에이전트들이 이종의 시스템에서 실행이 되지 않고 있다. 이러한 문제를 해결하기 위하여 OMB(Object Management Group, Inc)는 이질적인 에이전트시스템간의 상호운용성(interoperability)과 이식성을 증진시킬 목적으로 MAF(Mobile Agent Facilities) 명세를 제안하였다. 본 논문에서는 OMG MAF 명세를 만족하는 이동 에이전트시스템을 Java 프로그래밍 언어를 이용하여 개발하였다.

• Proceedings of the Korea Information Processing Society Conference
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• 2005.11a
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• pp.155-158
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• 2005

본 논문에서는 MPEG 의 멀티미디어 응용 표준인 MAF(Multimedia Application Format)를 기반으로, 효율적인 비디오 콘텐츠의 검색 및 활용을 위한 통합 미디어 구조, 즉 비디오 MAF 를 제안한다. 제안하는 비디오 MAF 는 ISO 미디어 포맷을 기반으로 하고 단일의 비주얼 스트림과 다중 음성을 지원하기 위한 다수의 오디오 스트림, 내용기반의 정보를 포함하는 메타데이터, 그리고 비디오 콘텐츠의 대표 이미지를 동시에 포함하는 구조이다. 제안하는 파일포맷의 유용성을 검증하기 위해 비디오 MAF 로 생성 및 해석할 수 있는 부호기(encoder)와 복호기(decoder)를 설계하고 구현하여, 통합 미디어에 내재된 메타데이터를 이용한 효율적인 검색과 멀티트랙의 오디오 스트림을 활용한 다중 음성에 대한 지원이 가능함을 확인하였다. 또한 내재된 대표이미지는 비디오 콘텐츠에 대한 브라우징이 효과적으로 활용됨을 확인하였다.

• Parasites, Hosts and Diseases
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• v.37 no.4
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• pp.277-283
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• 1999

To investigate the development of a subunit vaccine against theileriosis in cattle, the DNA fragments encoding piroplasm surface protein (p33) of Theileria sergenti of a Korean isolate were expressed in baculoviruses. The expressed p33 was characterized by indirect fluorescent antibody (IFA) and western blotting analysis. The expression of p33 was mainly detected on the surface of infected Sf21 cells by IFA. The immunoblotting analysis revealed the presence of a same molecular weight protein band of p33. The antigenicity of expressed polypeptide was further examined through the inoculation of a guinea pig. The sera of guinea pigs immunized with p33 expressed cell Iysate showed similar fluorescent antibody patterns and reacted with the same molecular weight protein of T. sergenti in immunoblotting analysis, thus indicating that this protein can be a promising candidate for a subunit vaccine in the future.

• Journal of Power Electronics
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• v.16 no.5
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• pp.1904-1917
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• 2016

The moving average filter (MAF) is widely utilized to improve the disturbance rejection capability of phase-locked loops (PLLs). This is of vital significance for the grid-integration and stable operation of power electronic converters to electric power systems. However, the open-loop bandwidth is drastically reduced after incorporating a MAF into the PLL structure, which makes the dynamic response sluggish. To overcome this shortcoming, some new techniques have recently been proposed to improve the transient response of MAF-based PLLs. In this paper, a comprehensive performance comparison of advanced MAF-based PLL algorithms is presented. This comparison includes HPLL, MPLC-PLL, QT1-PLL, and DMAF-PLL. Various disturbances, such as grid voltage sag, voltage flicker, harmonics distortion, phase-angle and frequency jumps, DC offsets and noise, are considered to experimentally test the dynamic performances of these PLL algorithms. Finally, an improved positive sequence extraction method for a HPLL under the frequency jumps scenario is presented to compensate for the steady-state error caused by non-frequency adaptive DSC, and a satisfactory performance has been achieved.

• Journal of Plant Biotechnology
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• v.33 no.4
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• pp.289-295
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• 2006

This study was carried out to evaluate the suitability of simple sequence repeat (SSR) markers for varietal identification and genetic diversity in 28 commercial tomato varieties. The relationship between marker genotypes and 28 varieties was analyzed. Of the 219 pairs of SSR primers screened against ten tomato varieties, 18 pairs were highly polymorphic with polymorphism information content (PIC) ranging from 0.467 to 0.800. Among the polymorphic loci, two to nine SSR alleles were detected for each locus with an average of 3.3 alleles per locus. Genetic distances were estimated according to Jaccard's methods based on the probability that the amplified fragment from one genotype would be present in another genotype. These varieties were categorized into cherry and classic fruit groups corresponding to varietal types and genetic distance of cluster ranging from 0.35 to 0.97. The phonogram discriminated all varieties by marker genotypes. The SSR markers proved to be useful variety identification and genetic resource analysis of tomato.

• Molecules and Cells
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• v.19 no.3
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• pp.428-435
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• 2005

This study was carried out to assess the potential of SSR markers for variety identification by comparing SSR markers and morphological traits in tests of distinctiveness, uniformity, and stability (DUS) of pepper (Capsicum annuum L.) varieties. Twenty-seven SSR markers were polymorphic in 66 pepper varieties, revealing a total of 89 alleles. Average polymorphism information content (PIC) value was 0.529, ranging from 0.03 to 0.877. Cluster analysis of the band patterns separated the varieties into three groups corresponding to varietal types. Morphological trait-based clustering showed some degree of similarity to dendrogram topologies based on the SSR index. However, no significance correlation was found between the SSR and morphological data. SSR markers could be used to complement a DUS test of a candidate variety and to select complimentary varieties by pre-screening existing varieties in the context of protecting new varieties of pepper.

• Proceedings of the Korean Society of Propulsion Engineers Conference
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• 2010.11a
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• pp.717-722
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• 2010

Supersonic/Hypersonic wind tunnel is a facility which is intended to test and to observe the physical phenomena around a model by creating supersonic flow in the test section. In designing an airplane, the wind tunnel test is demanded to analyzing aerodynamic characteristics of the model without making a prototype. In this research, the model aerodynamic facility(MAF) is modified for the purpose of increasing running time and its functionality. New pneumatic valves for remote control was installed for safety requirement, and new air tanks was installed on MAF as well. A pipe system is also modified to use those new valves and tanks, and the ceiling and side glasses of the test section are switched to ones with the larger surface area. After the MAF modification, a test is performed at Mach 2, 3 and 4. In this test, shadow graph technique, one of the flow visualization methods, is used to visualize supersonic flow field. The pressure in the settling chamber and working section at Mach 2, 3 and 4 was measured in each case. As a result, the possible model size and running time are obtained.