• Title/Summary/Keyword: MAE

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Overall Survival of Filipino Patients with Squamous Cell Carcinoma of the Head and Neck: A Single-Institution Experience

  • Albano, Pia Marie;Lumang-Salvador, Christianne;Orosa, Jose;Racelis, Sheryl;Leano, Modesty;Angeles, Lara Mae;Ramos, John Donnie
    • Asian Pacific Journal of Cancer Prevention
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    • v.14 no.8
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    • pp.4769-4774
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    • 2013
  • This paper is the first to present the incidence and overall survival of patients with squamous cell carcinoma of the head and neck (SCCHN) from the extreme northern part of the Philippines. We retrospectively retrieved the records of patients with histologically-confirmed squamous cell carcinoma of the oral cavity, oropharynx, hypopharynx and larynx at the Mariano Marcos Memorial Hospital and Medical Center, Ilocos Norte, Philippines, from 2003 to 2012 and analysed prognostic factors associated with survival. Of the 150 cases, only 80 (53.3%) were still living when the study was terminated. Median age at initial diagnosis was 61.5 years and the male to female ratio was 7:3. The majority of the cases had tumours in the oral cavity (50.7%), followed by the larynx (36.7%). Sex (log rank=1.94, p value/${\alpha}$=0.16), tumor site (log rank=0.02, p value/${\alpha}$=0.90), tumor grade (log rank=1.74, p value/${\alpha}$=0.42), and node stage (log rank=0.07, p value/${\alpha}$=0.80) were not shown to be associated with the survival of our cases. Only 45 (30.0%) had no regional lymph node involvement (N0) at presentation and 12 (8.0%) had already developed distant metastases. Among the 150 patients, 71 (47.3%) were not able to receive treatment of any kind. Oddly, treatment (log rank=1.65, p value/${\alpha}$=0.20) was also shown to be not associated with survival. The survival rate of those who underwent surgery, radiotherapy, or both was not statistically different from those who did not receive any treatment. Only the tumor stage (log rank=4.51, p value/${\alpha}$=0.03) was associated with patient survival. The overall mean survival was 49.3 months, with survival rate diminishing from 88.3% during the 1st year to 1.80% by end of the study. This relatively low survival rate of our cases only reflects their poor access to quality diagnostic and treatment facilities.

A Study on the Field Application of Nays2D Model for Evaluation of Riverfront Facility Flood Risk (친수시설 홍수위험도 평가를 위한 Nays2D 모형의 현장 적용에 관한 연구)

  • Ku, Young Hun;Song, Chang Geun;Park, Yong-Sung;Kim, Young Do
    • KSCE Journal of Civil and Environmental Engineering Research
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    • v.35 no.3
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    • pp.579-588
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    • 2015
  • Recent climage changes have resulted in increases in rainfall intensity and flood frequency as well as the risk of flood damage due to typhoons during the summer season. Water-friendly facilities such as ecological parks and sports facilities have been established on floodplains of rivers since the river improvement project was implemented and increases in the flood levels of rivers due to typhoons can lead to direct flood damage to such facilities. To analyze the hydraulic influence of these water-friendly facilities on floodplains or to evaluate their stability, numerical analysis should be performed in advance. In addition, it is crucial to address the drying and wetting processes generated by water level fluctuations. This study uses a Nays2D model, which analyzes drying and wetting, to examine its applicability to simple terrain in which such fluctuations occur and to natural rivers in which drying occurs. The results of applying this model to sites of actual typhoon events are compared with values measured at water level observatories. Through this comparison, it is determined that values of coefficient of determination ($R^2$), mean absolute error (MAE), and root-mean-square error (RMSE) are 0.988, 0.208, and 0.239, respectively, thus showing a statistically high correlation. In addition, the results are used to calculate flood risk indices for evaluation of such risk for water-friendly facilities constructed on floodplains.

Development of "Movie Production Project" Science-Arts Convergence STEAM Program and its Effects on Elementary School Students' Career Orientation of Science, Career Awareness and Creative Personality ("영화공작소" 과학·예술 융합형 융합인재교육(STEAM) 프로그램 개발 및 초등학생의 과학 진로지향도, 진로인식 및 창의적 성향에 미치는 영향)

  • Yoo, Mi Hyun;Park, Gi-Su;Chang, Woo Jin;Suk, Hae Jung;Kim, Sunghwan;Park, Mun Sook;Lee, Jina;Lee, Chong-Sup;Jin, Suk Hee;Yu, Hwasoo;Jung, Hyunji;Choi, Jung Jin;Kang, Yun Hee
    • Journal of Science Education
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    • v.40 no.1
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    • pp.31-51
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    • 2016
  • The purpose of this study was to develop "Movie Production Project" Science-Arts convergence STEAM program for elementary students and investigate the effects of the program on career orientation of science, career awareness and creative personality. Participants were 82 elementary school students. The results of this study were as follows: First, experimental group's total score of career orientation of science was significantly higher than that of comparative group. Among sub-areas, science learning preference, science career preference and perception on science career worth were significantly different between two groups. Experimental group's scores were significantly higher than those of comparative group. Second, experimental group's career awareness total score was significantly higher than that of comparative group including all sub-areas. Third, experimental group's creative personality total score was significantly higher than that of comparative group including 2 sub-areas, independence, openness. Finally, experimental group student's perception on the program showed that it was interesting, a little easy and they hoped to study again.

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Immature Development, Longevity and Fecundity of the Larval Parasitoid, Meteorus pulchricornis (Wesmael) (Hymenoptera: Braconidae), on Tobacco Cutworm

  • Hwang, Seok-Jo;Byeon, Young-Woong;Lee, Seol-Mae;Kim, Jeong-Hwan;Choi, Man-Young;Kim, Sung-Hyun;Kim, Nam-Jeong;Park, Hae-Chul;Lee, Young-Bo;Lee, Sang-Beom;Lee, Jong-Wook
    • International Journal of Industrial Entomology and Biomaterials
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    • v.21 no.2
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    • pp.180-183
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    • 2010
  • This study was performed to investigate the temperature-dependent development, longevity and oviposition of an indigenous larval parasitoid, Meteorus pulchricornis, on tobacco cutworm, Spodoptera litura. M. pulchricornis were reared at nine constant temperatures between 15 and $35^{\circ}C$. The developmental times of each three developmental stage decreased from 38.7 to 16.3 d between 15 and $30^{\circ}C$. However, M. pulchricornis showed longer developmental time at $32.5^{\circ}C$ (9.5, 7.7 and 17.2 days for each three developmental stage) than at $30^{\circ}C$ (8.9, 7.3 and 16.3 days for each three developmental stage). Immature M. pulchricornis could not develop any more at $35^{\circ}C$. The lower developmental threshold estimated by linear regression equation for the egg to cocoon, cocoon to adult emergence and egg to adult emergence were 5.1, 4.6 and $4.5^{\circ}C$. The thermal constant for each of the three stages were 217.2, 176.2 and 403.8 degree-days, respectively. When no food or 50% honey solution as a food source is provided for M. pulchricornis, the parasitoid survived for 8.3 and 55.9 days at $25^{\circ}C$, respectively. M. pulchricornis females laid 5.2 eggs daily and total of 131.6 eggs at $25^{\circ}C$ until it died. Peak age-specific fecundity was observed on $14^{th}$ day (9.6 cocoons) after parasitoid emergence and gradually decreased thereafter.

Daily Reservoir Inflow Prediction using Quantitative Precipitation Model (강수진단모형을 이용한 실시간 저수지 일유입량 예측)

  • Kang, Boo-Sik;Kang, Tae-Ho;Oh, Jai-Ho;Kim, Jin-Young
    • Proceedings of the Korea Water Resources Association Conference
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    • 2007.05a
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    • pp.291-295
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    • 2007
  • 강수진단모형을 이용하여 저수지 이수운영을 위한 실시간 유량예측기법을 개발하였다. 강수진단모형은 현재 기상청 현업에서 수행중인 강우수치예보를 기반으로 상세 지역의 지형 효과에 의한 강수를 예측하는 정량강수예측모형(QPM; Quantitative Precipitation Model)으로서 부경대학교 환경대기과학과에서 개발된 모형이다. QPM은 중규모 예측 모형으로부터 계산된 수평 바람, 고도, 기온, 강우 강도, 그리고 상대습도 등의 예측 자료를 이용하고, 소규모 상세지형 효과를 고려함으로써 중규모 예측 모형에서 생산된 강수량 예측 값을 상세 지역의 지형을 고려한 강수량 예측 값으로 재구성하여 결과적으로 3km 간격의 상세지역 강우산출과 지형에 따른 강수량의 분포 파악이 용이할 뿐만 아니라 계산 효율성을 개선된 모형이다. QPM 검증을 위하여 기상학적 평가와 수문학적 평가를 수행하였다. 호우 사례별 일강수량의 시공간 분포로 부터, QPM을 활용한 시스템에 의한 예측결과가 원시자료 RDAPS 보다 고해상도의 예측 및 지형효과의 반영도가 높았으며, AWS의 관측자료와 비교하여 보다 높은 예측성을 보여 주었다. 대상기간인 2006년 1월 1일부터 6월 20일까지 관측강우는 총 391.5mm 였으며 RQPM은 실적강우에 비하여 119.5mm 정도 과소산정하고 있으나 분위사상과정을 거치게 되면 351.7mm로서 실적강우에 불과 10.2% 못미치고 있다. 이는 고무적인 결과로 볼 수 있으며 현업에서의 활용성이 기대되는 수준이라 볼 수 있다. 강우-유출모의를 위한 QPM신뢰도를 높이기 위하여 분위사상법(Quantile Mapping)을 이용하여 QPM모의에 존재할 수 있는 계통오차에 대한 추가적인 보정을 수행하였다. 수문학적 평가를 위하여는 장기연속유출모형인 SSARR모형을 기반으로 개발된 RRFS(Rainfall-Runoff Forecast System)을 이용하여 2006년 1월${\sim}$9월까지의 용담댐 유입량에 대하여 모의예측결과와 관측유입량 비교를 통한 검증을 수행하였다. 위 기간중 예측유입량의 RMSE(Root Mean Squared Error), COE(Sutcliffe Coefficient of Efficiency), MAE(Mean Absolute Error), $R^2$값은 각각 7.50, 0.68, 2.59, 0.69 값을 보이고 있다. 본 연구에서는 QPM에 의한 예측성의 향상 및 구축된 시스템에 의한 일강수량의 장기예측 가능성을 확인하였고, 향후 시스템을 현업에 활용하기 위해서 생산된 예측자료의 보다 장기적인 검증을 통한 시스템의 안정화가 필요할 것으로 사료된다.

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Evaluation and Comparison of Meteorological Drought Index using Multi-satellite Based Precipitation Products in East Asia (다중 위성영상 기반 강우자료를 활용한 동아시아 지역의 기상학적 가뭄지수 비교 분석)

  • Mun, Young-Sik;Nam, Won-Ho;Kim, Taegon;Hong, Eun-Mi;Sur, Chanyang
    • Journal of The Korean Society of Agricultural Engineers
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    • v.62 no.1
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    • pp.83-93
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    • 2020
  • East Asia, which includes China, Japan, Korea, and Mongolia, is highly impacted by hydroclimate extremes such drought, flood, and typhoon recent year. In 2017, more than 18.5 million hectares of crops have been damaged in China, and Korea has suffered economic losses as a result of severe drought. Satellite-derived rainfall products are becoming more accurate as space and time resolution become increasingly higher, and provide an alternative means of estimating ground-based rainfall. In this study, we verified the availability of rainfall products by comparing widely used satellite images such as Climate Hazards Groups InfraRed Precipitation with Station (CHIRPS), Global Precipitation Climatology Centre (GPCC), and Precipitation Estimation From Remotely Sensed Information Using Artificial Neural Networks-Climate Data Record (PERSIANN-CDR) with ground stations in East Asia. Also, the satellite-based rainfall products were used to calculate the Standardized Precipitation Index (SPI). The temporal resolution is based on monthly images and compared with the past 30 years data from 1989 to 2018. The comparison between rainfall data based on each satellite image products and the data from weather station-based weather data was shown by the coefficient of determination and showed more than 0.9. Each satellite-based rainfall data was used for each grid and applied to East Asia and South Korea. As a result of SPI analysis, the RMSE values of CHIRPS were 0.57, 0.53 and 0.47, and the MAE values of 0.46, 0.43 and 0.37 were better than other satellite products. This satellite-derived rainfall estimates offers important advantages in terms of spatial coverage, timeliness and cost efficiency compared to analysis for drought assessment with ground stations.

Predicting Cherry Flowering Date Using a Plant Phonology Model (생물계절모형을 이용한 벚꽃 개화일 예측)

  • Jung J. E.;Kwon E. Y.;Chung U. R.;Yun J. I.
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.7 no.2
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    • pp.148-155
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    • 2005
  • An accurate prediction of blooming date is crucial for many authorities to schedule and organize successful spring flower festivals in Korea. The Korea Meteorological Administration (KMA) has been using regression models combined with a subjective correction by forecasters to issue blooming date forecasts for major cities. Using mean monthly temperature data for February (observed) and March (predicted), they issue blooming date forecasts in late February to early March each year. The method has been proved accurate enough for the purpose of scheduling spring festivals in the relevant cities, but cannot be used in areas where no official climate and phenology data are available. We suggest a thermal time-based two-step phenological model for predicting the blooming dates of spring flowers, which can be applied to any geographic location regardless of data availability. The model consists of two sequential periods: the rest period described by chilling requirement and the forcing period described by heating requirement. It requires daily maximum and minimum temperature as an input and calculates daily chill units until a pre-determined chilling requirement for rest release. After the projected rest release date, it accumulates daily heat units (growing degree days) until a pre- determined heating requirement for flowering. Model parameters were derived from the observed bud-burst and flowering dates of cherry tree (Prunus serrulata var. spontanea) at KMA Seoul station along with daily temperature data for 1923-1950. The model was applied to the 1955-2004 daily temperature data to estimate the cherry blooming dates and the deviations from the observed dates were compared with those predicted by the KMA method. Our model performed better than the KMA method in predicting the cherry blooming dates during the last 50 years (MAE = 2.31 vs. 1.58, RMSE = 2.96 vs. 2.09), showing a strong feasibility of operational application.

Validation of Nursing Diagnose and Defining Characteristics for Patients with Cerebrovascular Accidents - Home Health Care Nursing (뇌혈관질환자와 관련된 간호진단 및 간호진단별 특성 규명과 타당성 조사연구 - 가정간호 대상자를 중심으로 -)

  • Kim, Hae-Young
    • Journal of Korean Academic Society of Home Health Care Nursing
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    • v.2
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    • pp.35-51
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    • 1995
  • This study was done to define nursing diagnose and to test the validity of the characteristics for patients with cerebrovascular accidents being seen at home by home health care nurses. This study was a descriptive study. The sample consisted of 10 experts(professors and home health care nurses) who had had a variety of experience using nursing diagnoses in clinical practice, and 336 nurse progress notes for 18 patients with cerebrovascular accidents. First, 32 nursing diagnoses were defined by the analysis of 336 nurse progress notes, and ten nursing diagnoses were selected according to a criteria of frequency and four nursing diagnoses from home health care clinical practice. Second, content validity was examined by an expert group which considered the sign / symtoms of the fourteen nursing diagnoses. The instrument used for this was a checklist for sign / symtoms based on the nurse progress notes and literature : Carpenito(1993), Kim Cho Ja et al (1994), Lee Sun Ok et al.(1994), Kim Mae Ja et al. (1992), Seoul University Hospital (1993) , Kim Mi Ja et al. (1991). The data were collected from March 1995 to April 1995. Data were analyzed using Content Validity Incidence where if 80% or more of the expert group agreed, characteristics were defined as a major sign/symtoms, if between 50% and 79% of the expert group agreed with the characteristic it was defined as a minor sign / symtoms. The results of this study are summarized as follows : 1. Thirty-two nursing diagnoses related to patients with cerebrovascular accidents were defined. There was a high frequency for the following : 'Potential for disuse syndrome (61%)', 'Impaired physical mobility(50%)', 'Impaired skin integrity (44.4%)', Potential for aspiration(33.3%)', 'Potential for infection: respiration(33.3%)', 'Self-care deficit : bathing /hygine(27.8%)', 'Ineffective family coping(22.2%)', 'Potential for trauma(22.2%)', 'Alteration in nutrition: less than body requirements(22.2%)'. The following diagnoses were also used in home health care clinical practice : 'Anxiety in family (50%)', 'Caregiver fatigue(27.8%)', 'Ineffective treatment behavior (22.2%)', 'Ineffective Levin tube management and Levin tube feeding(22.2%)'. Fourteen nursing diagnoses were selected. 2. Ten of the nursing diagnoses for patients with cerebrovascular accident were listed as nursing diagnoses by NANDA but four nursing diagnoses were new nursing diagnoses used in home health care clinical practice. 3. Characteristics of the ten Nursing Diagnoses from NANDA were developed from the sign /symtoms in the literature and in the nurse progress notes. These characteristics was verified as major or minor sign / symtoms by the expert group. 4. Characteristics of the four nursing diagnoses used in home health care were not defined by the literature but only by the nurse progress notes and verified as major or minor signs /symtoms by the expert group. On the basis of the findings of this study, the following recommendations are made : 1. Continual study is necessary to identify other signs /symtoms not verified in this study. 2. It is necessary to use verified signs /symtoms in home health care clinical practice. 3. It is necessary to define related factors which define each diagnoses in this study. 4. It is necessary to develop of standardized nursing are plans which include defined signs and symtoms. 5. It is necessary to study the outcomes of the standardized nursing care plans.

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The Shape of Synaptic Vesicles in the Tooth Pulp Afferent Terminals and P-endings in the Rat Trigeminal Nucleus Principalis (흰쥐의 삼차신경주감각핵에서 치수유래 일차들신경종말 및 이와 연접하는 연접이전신경종말의 연접소포 형태 비교)

  • Kim, Yun-Sook;Paik, Sang-Kyoo;Kwak, Woo-Kyung;Cho, Yi-Sul;Kim, Ji-Man;Park, Mae-Ja;Bae, Yong-Chul
    • Applied Microscopy
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    • v.38 no.4
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    • pp.375-382
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    • 2008
  • In order to investigate shape of synaptic vesicles of the tooth pulp afferent boutons and their presynaptic endings (p-endings), and the neuroactive substance of the p-endings in the trigeminal nucleus principalis, rat incisor tooth pulp afferents were labeled by the horseradish peroxidase (HRP) and quantitative ultrastructural analysis and postembedding immunogold labeling were performed. Labeled tooth pulp afferent boutons contained clear, spherical synaptic vesicles (diameter: $45{\sim}55\;nm$) and occasionally dense core vesicles(diameter: $80{\sim}120\;nm$). They formed symmetrical synapses with unlabeled axon terminals (p-endings) containing pleomorphic synaptic vesicles. The ratio of short to long diameter (form factor) of synaptic vesicles of pulp afferent boutons was 0.6 to 0.99, whereas that of p-endings was 0.25 to 0.99. In addition, most of the p-endings showed GABA-like immunoreactivity. These results indicate that the shape of synaptic vesicles is quite different between the tooth pulp afferent boutons and p-endings, and the p-endings may contain GABA as a neuroactive substance in the trigeminal nucleus principalis.

Optimization of Lipase-Catalyzed Interesterification for Production of Human Milk Fat Substitutes by Response Surface Methodology (반응표면분석에 의한 모유대체지의 효소적 합성조건 최적화)

  • Son, Jeoung-Mae;Lee, Jeung-Hee;Xue, Cheng-Lian;Hong, Soon-Taek;Lee, Ki-Teak
    • Korean Journal of Food Science and Technology
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    • v.43 no.6
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    • pp.689-695
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    • 2011
  • 1,3-Dioleoyl-2-palmitoylglycerol (OPO)-rich human milk fat substitute (HMFS) was synthesized from tripalmitin (PPP)-rich fraction and oleic ethyl ester by a lipase-catalyzed interesterification. Response surface methodology (RSM) was employed to optimize the presence of palmitic acid at sn-2 position ($Y_1$, %) and of oleic acid at sn-1,3 ($Y_2$, %), with the reaction factors as substrate molar ratio of PPP-rich fraction to oleic ethyl ester ($X_1$, 1:4, 1:5 and 1:6), reaction temperature ($X_2$, 50, 55 and $60^{\circ}C$), and time ($X_3$, 3, 7.5 and 12 h). The optimal conditions for HMFS synthesis were predicted at the reaction combination of $55^{\circ}C$, 3 h and 1:6 substrate ratio. HMFS re-synthesized under the same conditions displayed 70.70% palmitic acid at the sn-2 position and 69.58% oleic acid at the sn-1,3 position. Reaction product was predominantly (90.35%) triacylglycerol (TAG) was observed in which the major TAG species, OPO, comprised 31.24%.