• KSBB Journal
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• v.21 no.1 s.96
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• pp.11-15
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• 2006

The biological activities of extracts from the fruit, stem, and leaf of Hovenia dulcis were examined. In the batch mode of operation, the fruit, stem, and leaf of Hovenia dulcis were extracted with hot water for 10 hr. The fruit extract of Hovenia dulcis gave the highest activity for decreasing alcohol concentration which was 138% of control. The equilibrium between bioactive compound in the fruit (size : 4 mm) and hot water solution was reached within 6 hr and the recovery was 95% by three-times extraction. The fruit extract of Hovenia dulcis showed significant alcohol decrease in blood and hepatoprotective activity against $CCl_4$-toxicity in rat. The fruit extract significantly inhibited the elevation of serum alanine aminotransferase (ALT), aspartate aminotransferase (AST), and lactate dehydrogenase (LDH) levels.

• Korean Journal of Oriental Medicine
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• v.4 no.1 s.4
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• pp.115-127
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• 1998

To improve the quality control of frequently used oriental medicinal plants, the storage, cutting, processing and decokting methods of Rehmannia glutinosa Libosch. var. purpurea Makino(熟地黃) were examined. The contents of 5-hydroxymethyl-2- furaldehyde(5-HMF) of Rehmannia glutinosa Libosch. var. purpurea Makino were analysed by HPLC at various conditions as the standard component. Raw materials were classified into 3 groups with their specific gravity(天 地 人黃) and determined the ding weights and the contents of water, the solid component of Ji-Hwang(地黃) was the most. Rehmannia glutinosa Libosch. var purpurea Makino was steamed and dried nine times and analysed the content of 5-HMF on every time. In the case of Ji-Hwang, the standard component of the ninth sample was produced the most. But which of the tenth samples of Chun-Hwang and Yin-Hwang(天黃 人黃) were the most. The best decokting conditions which were determined by the yield of 5-HMF were as follows : non cutting, soaking time was 0 minutes, decokting time was 75 minutes after boiling. The contents of sugar on each of samples were determined. The contents of standard component increased by steaming number and the contents of sugar decreased.

• Korean Journal of Oriental Medicine
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• v.17 no.3
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• pp.115-121
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• 2011

Objective : The purpose of this study was to investigate the changes in the contents of constituents in Socheongryong-tang (CY) and its fermentations (FCY) with 10 species of lactic acid bacteria. Methods : Ten strains of lactic acid bacteria, Lactobacillus casei 127, L. acidophilus 128, L. casei 129, L. plantarum 144, L. amylophilus 161, L. curvatus 166, L. delbruekil subsp. lactis 442, L. casei 693, B. breve 744, and B. thermophilum 748, were used for the fermentation of Socheongryong-tang. The increased and decreased constituents were identified using HPLC/DAD and various liquid chromatographic techniques, and the structure was elucidated using NMR and MS. These compounds were quantitatively analyzed using an HPLC/DAD system. Results : The increased constituents were identified to be liquiritigenin (1) and cinnamyl alcohol (2), and the decreased constituent was determined to be liquiritin (3). Liquiritigenin (1) and cinnamyl alcohol (2) were increased in all of the FCYs, while liquiritin (3) was decreased. The fermentation of the ten lactic acid bacteria demonstrated that the decomposable rate of these three compounds in FCYs were different. Socheongryong-tang fermented by L. plantarum 144 and L. amylophilus 161 showed the most remarkable changes. Conclusions : CY could be increased antibacterial, neuroprotective, or antiinflammatory effect by fermentation with lactic acid bacteria, especially with L. plantarum and L. amylophilus, considering their known biological activities. In addition, it is expected that this study will help to establish quality control parameters for FCY.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.9 no.6
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• pp.1511-1517
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• 2008

The magneto-rheological fluid expresses different cohesiveness according to the strength of the external electric current. The magneto-rheological fluid damper, which uses such characteristics of the fluid, generates shear force due to the fluid's cohesiveness. The core can be said to determine the magneto-rheological fluid damper's performance. This study uses the finite element analysis to compare the performance of different electromagnetic forces, which are affected by the shapes of the coil, and thus to find the optimum design for the core. In addition, as a step to construct a high-efficient damper, we suggest a type of damper that can control multiple coils and compares the performance of this damper and that of the standard damper by comparing the performance of their electro-magnetic fields.

• The KIPS Transactions:PartC
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• v.9C no.2
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• pp.283-292
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• 2002

This paper develops a scheme of resource management for guaranteeing QoS of realtime traffic in wireless mobile internet environments Mobile terminal has significant impact on the QoS originating mobility provided to a real-time application. The currently proposed MRSVP is not clear the boundary of resource reservation tregion and also can give rise to signal overhead to maintain sessions. To solve above problem, we propose the new reservation protocol, mobile cluster based H-MRSVP to combine MRSVP with moving cluster concept. In this paper, we analytically design our model for guaranteeing the QoS of realtime traffic and compare the three schemes: guard channel allocation schemes, DCA and our model. The performance measures are the probabilities of new call blocking, handoff dropping, resource utilization and service completion versus the system offered Erlang load. Consequently, Simulation indicate our model is more flexible than DCA in a view pint of channel utilization and gains the advantage over guard channel scheme with respects to the mobility.

• Korean Journal of Applied Biomechanics
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• v.26 no.4
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• pp.369-375
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• 2016

Objective: The purpose of this study was to investigate the possibility of injuries and the types of movement related to damage by body parts, and to prepare for prevention of injuries and development of a training program. Method: For this study, the experiment was conducted according to levels of 60 percentages (ST) and 85 percentages (MA) and 10 subjects from the Korean elite national weightlifting team were included. Furthermore, we analyzed joint moment and muscle activation pattern with three-dimensional video analysis. Ground reaction force and EMG analyses were performed to measure the factors related to injuries and motion. Results: Knee reinjuries such as anterior cruciate ligament damage caused by deterioration of the control ability for the forward movement function of the tibia based on the movement of the biceps femoris when the rectus femoris is activated with the powerful last-pull movement. In particular, athletes with previous or current injuries should perceive a careful contiguity of the ratio of the biceps femoris to the rectus femoris. This shows that athletes can exert five times greater force than the injury threshold in contrast to the inversion moment of the ankle, which is actively performed for a powerful last pull motion and is positively considered in terms of intentional motion. It is activated by excessive adduction and internal rotation moment to avoid excessive abduction and external rotation of the knee at lockout motion. It is an injury risk to muscles and ligaments, causing large adduction moment and internal rotation moment at the knee. Adduction moment in the elbow joint increased to higher than the injury threshold at ST (60% level) in the lockout phase. Hence, all athletes are indicated to be at a high risk of injury of the elbow adductor muscle. Lockout motion is similar to the "high five" posture, and repetitive training in this motion increases the likelihood of injuries because of occurrence of strong internal rotation and adduction of the shoulder. Training volume of lockout motion has to be considered when developing a training program. Conclusion: The important factors related to injury at snatch include B/R rate, muscles to activate the adduction moment and internal rotation moment at the elbow joint in the lockout phase, and muscles to activate the internal rotation moment at the shoulder joint in the lockout phase.

• The Plant Pathology Journal
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• v.31 no.4
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• pp.414-420
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• 2015

Antifungal activities of crude extractum of Nanshancha Seed Cake (NSC), to inactivate postharvest pathogens were investigated. Highest inhibitory rate was found against C. musae, C. gloeosporioides and C. papaya P.Henn, which was much stronger than that by tea saponin. Compared to tea saponin, effects of NSC extractum was relatively weak and similar on C. gloeosporioides Penzig and P. italicum. In an in vivo study, best controlling effects by NSC extractum was found with banana anthracnose disease development, which showed no inhibitory effects by tea saponin. NSC extractum controlled in vitro C. musae growth through directly inhibiting germination rate and germ tube elongation, and causing distortation, rupture and indentation of C. musae mycelium. In banana fruit subject to C. musae inoculation, higher PAL, POD, GLU and CHT activity was observed in banana fruit treated with crude NSC extractum than that of water control fruits. Current study proved the best controlling effects of crude NSC extractum in C. musae in vitro and in vivo development, which through direct inhibition of C. musae growth and increasing defense system of the banana fruit.

• Toxicological Research
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• v.12 no.2
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• pp.277-281
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• 1996

To evaluate the renal toxicity of the antitumor agent, 5-(piperidonomethylphenyl)-2,3-dihydroimidazo[2,1-a]isoquinoline (SDZ-62-434), rats were treated with SDZ-62-434 of 50 mg/Kg, i.p., once and 10 mg/Kg, i.p., daily for 7 days. The kidney weights and urine volume after and during the treatment were observed. The concentrations of urinary creatinine, protein, and the activities of N-acetyl-$\beta $D-glucosaminidase (NAG), alanine aminopeptidase (AAP), $\gamma$-glutamyl transpeptidase (GGT) and lactate dehydrogenase (LDH) in 24 hr urine were also determined. The kidney weights after acute and subacute administration was not affected. The urine excretions were increased 5 days after the acute administration and increased after the daily 3rd day-administration. The excretion of creatinine was similar as that of urine excretion. The excretion of creatinine was increased 5 days after the acute and subacute administration. However, the protein excretion didn't changed in both treatment. Those indicate that SDZ-62-434 might induce the diuresis and also suggest that diuresis might be due to the some metabolites rather than the compound itself. The urinary activities of NAG and LDH were not affected after the acute treatment. However, the urinary activities of AAP and GGT were slightly increased 3 days after the acute administration but, returned to the control value. In subacute treatment, the activities of GGT was not changed. And the activities of NAG were declined after the 7th day-administration. However, the activities of AAP were significantly increased after the 5th day-administration. Furthermore, the urinary activities of LDH were continuously increased during the subacute administration. These results indicate that the high and subacute administration might induce a weak damage on the kidney cells. Furtherrnore, the present results suggest that SDZ-62-434 might have relatively slow-emerging and mild toxicity to the kidney.

• Biomolecules & Therapeutics
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• v.20 no.4
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• pp.413-417
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• 2012

Chrysanthemum indicum Linne is an ancient herbal medicine used to treat bone and muscle deterioration, ocular inflammation, headache, and anxiety in Korea, China, and Japan. Furthermore, tea derived from Chrysanthemum indicum Linne has been used to treat anxiety by facilitating relaxation and curing insomnia. However, no reports exist on the anxiolytic-like effects of Chrysanthemum indicum Linne water extract (CWE) in mice. In the present study, we investigated the anxiolytic-like effects of CWE using the elevated plus-maze (EPM) test in mice. CWE, at a dose of 500 mg/kg (p.o.), significantly increased the time spent in the open arms of the EPM compared to a vehicle-injected control group. Moreover, the effect of CWE (500 mg/kg) was blocked by bicuculline (a selective $GABA_A$ receptor antagonist) and WAY 100635 (a selective 5-$HT_{1A}$ receptor antagonist). Taken together, these findings suggest that the anxiolytic-like effects of CWE might be mediated by the $GABA_A$ receptor and the 5-$HT_{1A}$ receptor.

• Proceedings of the KIPE Conference
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• 2016.11a
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• pp.171-173
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• 2016

일반적으로 대형 버스 및 트럭 등 같은 경우, 부하가 아주 크다. 또한 내리막길이나 장거리 운행 시에 잦은 제동으로 인하여 마찰을 이용한 기존 방식의 브레이크들은 브레이크 파열 및 페이드 현상 때문에 제동 안전성에 문제가 있다. 이러한 제동 부담을 분담하기 위해 현재 보조브레이크(리타더)가 필수적이며, 엔진 계통의 보조브레이크가 아닌 비접촉식 브레이크 같은 친환경 보조브레이크가 요구되고 있다. 그리고 차량 제동시 발생하는 기계에너지를 전기에너지로 회생하여 에너지효율을 향상시키려는 연구가 현재 활발히 진행되고 있다. 본 논문에서는 와전류를 이용한 전자기형 리타더에서 발생되는 전기에너지를 회수하기 위한 전압 제어 방법을 다룰 것이다. 리타더의 제동에너지를 전기에너지로 회생하기 위해 L-C 공진회로로 구성하였다. 리타더를 자여자 유도발전기(Self-Excited Induction Generator)로 모델링 하였고 이를 토대로 시뮬레이션 및 실험을 진행하였다. 자여자 유도발전기의 구동 조건에 대해서 언급하고 이를 파라미터에 따라 3-D map으로 만들었다. 또 회로 중의 FET 게이트에 전압을 인가하는 제어장치의 구동펄스에 따라 바뀌는 공진회로의 전압을 분석하였으며, 이 전압을 제어하기 위하여 PI 제어기를 이용한 알고리즘을 제안하였다. 이 전압을 3상 AC/DC컨버터를 통과한 후 DC/DC컨버터를 통하여 차량 내부의 배터리에 충전되는데 제어를 위해 3상 AC/DC에서의 전압 리플을 MA(Moving Average) 방식의 필터를 사용하여 DC/DC컨버터의 입력에 맞도록 제어하였다. 이와 같이 전자기형 리타더에서 유도되는 전압을 제어기의 제어 펄스에 따라 제어할 수 있으며 Matlab Simulink를 이용하여 리타더의 모델과 그 제어기의 타당성을 보였다. 또 실제 M-G Set 실험을 통하여 그 연관성을 확인하였다.