• Nuclear Medicine and Molecular Imaging
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• v.42 no.4
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• pp.275-284
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• 2008

Purpose: We intended to evaluate myocardial oxygen consumption ($MVO_2)$ by applying recirculation correction and modified one-compartment model to have a reference range of $MVO_2$ in normal young population and to reveal the effect of recirculation on time-activity curve (TAC). Materials and Methods: In nine normal male volunteers with mean age of $26.3{\pm}4.0$, $MVO_2$ was estimated with 925 MBq (25mCi) of $^{11}C$-Acetate (Neuroscience Research Institute, Gachon University of Medicine and Science, Incheon, Korea) and PET/CT (Biograph 6, Siemens Medical Solution, Germany). Analysis software such as $MATLAB^{(R)}$ v7.1 (Mathworks, Inc., United States), $Excel^{(R)}$ 2007 (Microsoft, United States), and $SPSS^{(R)}$ v12.0 (Apache Software Foundation, United States) were used. Twenty three frames were of $12{\times}10$, $5{\times}60$, $3{\times}120$, $2{\times}300's$ duration, respectively. The modified one-compartmental model and the recirculation correction method were applied. Statistical analysis was performed by using Test of Normality, ANOVA and Post-Hoc (Scheffe's) analysis, and p-value less than 0.05 was considered as significant. Results: The normal reference ranges of $MVO_2$ were presented as $3.18-4.64\;{\times}\;10^{-4}\;ml/g/sec$, $1.91-3.94\;{\times}\;10^{-4}\;ml/g/sec$, $4.31-6.40\;{\times}\;10^{-4}\;ml/g/sec$, $2.84-4.53\;{\times}\;10^{-4}\;ml/g/sec$ and $3.42-5.00\;{\times}\;10^{-4}\;ml/g/sec$ in the septum, the inferior wall, the lateral wall, the anterior wall and the entire wall, respectively. In addition, it was noted that the dual exponentiality of the clearance curve is due to the recirculation effect and that the characteristic of the curve is essentially mono-exponential. Conclusion: $^{11}C$-Acetate is a radiotracer worthwhile to assess $MVO_2$. Re-circulated $^{11}C$ can influence TAC of $^{11}C$ in myocadia and so the recirculation correction must be considered when measuring $MVO_2$.

• The Sea:JOURNAL OF THE KOREAN SOCIETY OF OCEANOGRAPHY
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• v.18 no.4
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• pp.163-177
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• 2013

An instrumented ferry made two transects per day across two current systems which are the North Korean Cold Current and the East Korean Warm Current over the years 2012-2013 from Gangneung to Ulleungdo in the southwestern East Sea. Seawater properties of these transects were measured with high spatial and temporal resolution for an extended period of time. Here the salinity records from the transects with the oceanographic observation data from East Sea Fisheries Institute of NFRDI, AVISO daily current chart and GOCI Chlorophyll-a image in 2012 and 2013 are used to study the time-series variation of salinity at the surface. The high salinity section with the range of 33.15~34.12 occurred on the transect mainly in the middle of eddy, and western boundary of strong northward current from June to October. We can found low salinity waters in both sides of the high salinity section. It is estimated that the western low salinity waters with the range of 30.58~33.20 accompanied by southward current were derived from the NKCC and the eastern waters with the range of 31.30~33.24 accompanied by northward current were derived from the Tsushima Surface Water. The lowest salinity of NKCC is confirmed in this study as 30.36. It is found that the western waters below 33.00 extended extremely toward the east about 110 km area from Gangneung and toward the south around Jukbyon coastal area as a 5~10 m layer. We can find its volume of low saline waters transport is not neglectable compared with that of Tsushima Current region in the western part of the East Sea. In this study we named it as the North Korean Low Saline Surface Water in summer.

• Horticultural Science & Technology
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• v.29 no.1
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• pp.29-35
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• 2011

Individual ion concentrations and ionic contributions to EC reading in the circulated nutrient solution are the important factors to be considered for stable EC-based closed-loop soilless culture. This study was conducted to determine appropriate ion-analysis intervals of the circulated nutrient solutions based on ion concentration, ion balance, and ion electrical conductivity under different renewal intervals in EC-based nutrient control systems for sweet peppers (Capsicum annum L. 'Fiesta') in early growth stage. Average node numbers of the plants were 13 and 18 when the experiment started and finished, respectively, and three plants were grown in each rockwool slab. Four different renewal intervals of circulated nutrient solutions such as 1, 2, 3, and 4 weeks were used as treatment. Nutrient solutions were supplied to the plants based on integrated radiation. Drainage was collected into drain tanks after irrigation ended in the day and then mixed with fresh water until the EC reaches 2.69 $dS{\cdot}m^{-1}$. The replenished nutrient solution was supplied to the plants in the next day. Ion concentrations of the individual ions periodically analyzed in the circulated nutrient solutions showed no significant differences among the treatments during the experimental period. Ion concentrations of $K^+$, $Ca^{2+}$, $Mg^{2+}$, $Na^+$, $NO_3{^-}$, ${SO_4}^{2-}$, ${PO_4}^{3-}$, and $Cl^-$ varied within 5-8, 11-14, 2.0-2.7, 0.5-0.6, 14-19, 4-5, 1-4, and 0.3-0.5 $meq{\cdot}L^{-1}$, respectively. Ion balance showed a consistent tendency over all the treatments and especially $K^+$ : $Ca^{2+}$ and ${SO_4}^{2-}$ : ${PO_4}^{3-}$ played great roles in the cation and anion balances in the nutrient solutions, respectively. Activity coefficients of ions such as $K^+$, $NO_3{^-}$, and $H_2PO_4{^-}$ varied within 0.8-0.9 and those of $Ca^{2+}$, $Mg^{2+}$, ${SO_4}^{2-}$ varied within 0.5-0.6, showing little changes with time. Ionic contributions of $K^+$ and $NO_3{^-}$ to EC reading were the greatest followed by $Ca^{2+}$, ${SO_4}^{2-}$, and $Mg^{2+}$ in the order. From the results, we thought that allowable ranges in ion concentration, ion balance, and subsequent individual ionic contributions to EC reading would be obtained within 4-week renewal interval of nutrient solution in EC-based closed-loop soilless culture for sweet pepper plants.

• Restorative Dentistry and Endodontics
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• v.32 no.1
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• pp.69-79
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• 2007

The purpose of this study was to investigate the effects of composite resin restorations on the stress distribution of notch shaped noncarious cervical lesion using three-dimensional (3D) finite element analysis (FEA). Extracted maxillary second premolar was scanned serially with Micro-CT (SkyScan1072 ; SkyScan, Aartselaar, Belgium). The 3D images were processed by 3D-DOCTOR (Able Software Co., Lexington, MA, USA). ANSYS (Swanson Analysis Systems, Inc., Houston, USA) was used to mesh and analyze 3D FE model. Notch shaped cavity was filled with hybrid or flowable resin and each restoration was simulated with adhesive layer thickness ($40{\mu}m$) A static load of 500 N was applied on a point load condition at buccal cusp (loading A) and palatal cusp (loading B). The principal stresses in the lesion apex (internal line angle of cavity) and middle vertical wall were analyzed using ANSYS. The results were as follows 1. Under loading A, compressive stress is created in the unrestored and restored cavity. Under loading B, tensile stress is created. And the peak stress concentration is seen at near mesial corner of the cavity under each load condition. 2. Compared to the unrestored cavity, the principal stresses at the cemeto-enamel junction (CEJ) and internal line angle of the cavity were more reduced in the restored cavity on both load con ditions. 3. In teeth restored with hybrid composite, the principal stresses at the CEJ and internal line angle of the cavity were more reduced than flowable resin.

• Journal of Bio-Environment Control
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• v.30 no.4
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• pp.367-376
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• 2021

Strawberry cultivation in Korea is grown in greenhouse, but most farms manage their water supply using a timer control method based on the experience of growers. The timer control has problems in that it is difficult to consider the weather condition, the growth stage of crops, and the moisture content of the substrate, so that the crops cannot be managed at an optimal level, and the accuracy of cultivation management are lacking. The watering methods using integrated solar irradiance and substrate moisture contents are control systems that provide eco-friendly and precise water supply considering the growth conditions of crops. The purpose of this study was to compare the combined water supply control with integrated solar irradiance and substrate moisture contents and timer control method in hydroponic cultivation of strawberries using coir, and to set the optimal integrated solar irradiance level for complex water supply control. The irrigation system was automatically watered when it reached 100, 150, 250 J·cm^-2 based on the external solar irradiance, and forced irrigation was performed at a substrate moisture content of less than 60% in all treatments. The amount of irrigation at once was 50 mL. The timer treatment was applied as a control. The smaller the level of integrated radiation to start watering, the greater the daily amount of irrigation. Both the fresh weight and dry weight per plant were higher in the complex irrigation control method than the timer control, and the 100 and 150 J·cm^-2 treatment had the highest fresh weight, and the 100 J·cm^-2 treatment showed a significantly higher dry weight. The yield was also significantly higher in the complex control method than in the timer, and the early yield increased as the level of integrated solar irradiance was smaller. The fresh weight of fruit was the lowest in the timer-controlled irrigation. As a result of this study, the possibility of combined control irrigation method using integrated solar irradiance and substrate moisture content was confirmed for precise water supply management of strawberries in hydroponics.

• Korean Journal of Remote Sensing
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• v.37 no.5_1
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• pp.959-974
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• 2021

Forel-Ule Index (FUI) is an index which classifies the colors of inland and seawater exist in nature into 21 gradesranging from indigo blue to cola brown. FUI has been analyzed in connection with the eutrophication, water quality, and light characteristics of water systems in many studies, and the possibility as a new water quality index which simultaneously contains optical information of water quality parameters has been suggested. In thisstudy, Ocean Colour-Climate Change Initiative (OC-CCI) based 4 km FUI was spatially downscaled to the resolution of 500 m using the Geostationary Ocean Color Imager (GOCI) data and Random Forest (RF) machine learning. Then, the RF-derived FUI was examined in terms of its correlation with various water quality parameters measured in coastal areas and its spatial distribution and seasonal characteristics. The results showed that the RF-derived FUI resulted in higher accuracy (Coefficient of Determination (R²)=0.81, Root Mean Square Error (RMSE)=0.7784) than GOCI-derived FUI estimated by Pitarch's OC-CCI FUI algorithm (R²=0.72, RMSE=0.9708). RF-derived FUI showed a high correlation with five water quality parameters including Total Nitrogen, Total Phosphorus, Chlorophyll-a, Total Suspended Solids, Transparency with the correlation coefficients of 0.87, 0.88, 0.97, 0.65, and -0.98, respectively. The temporal pattern of the RF-derived FUI well reflected the physical relationship with various water quality parameters with a strong seasonality. The research findingssuggested the potential of the high resolution FUI in coastal water quality management in the Korean Peninsula.

• Journal of the Korean earth science society
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• v.43 no.1
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• pp.60-76
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• 2022

This study presents a software full setup and the following test execution times in a Linux cluster for the United Kingdom Earth System Model (UKESM) and then compares the model results from control and experimental simulations of the UKESM relative to various observations. Despite its low resolution, the latest version of the UKESM can simulate tropospheric chemistry-aerosol processes and the stratospheric ozone chemistry using the United Kingdom Chemistry and Aerosol (UKCA) module. The UKESM with UKCA (UKESM-UKCA) can treat atmospheric chemistryaerosol-cloud-radiation interactions throughout the whole atmosphere. In addition to the control UKESM run with the default CMIP5 SO₂ emission dataset, an experimental run was conducted to evaluate the aerosol effects on meteorology by changing atmospheric SO₂ loading with the newest REAS data over East Asia. The simulation period of the two model runs was 28 years, from January 1, 1982 to December 31, 2009. Spatial distributions of monthly mean aerosol optical depth, 2-m temperature, and precipitation intensity from model simulations and observations over East Asia were compared. The spatial patterns of surface temperature and precipitation from the two model simulations were generally in reasonable agreement with the observations. The simulated ozone concentration and total column ozone also agreed reasonably with the ERA5 reanalyzed one. Comparisons of spatial patterns and linear trends led to the conclusion that the model simulation with the newest SO₂ emission dataset over East Asia showed better temporal changes in temperature and precipitation over the western Pacific and inland China. Our results are in line with previous finding that SO₂ emissions over East Asia are an important factor for the atmospheric environment and climate change. This study confirms that the UKESM can be installed and operated in a Linux cluster-computing environment. Thus, researchers in various fields would have better access to the UKESM, which can handle the carbon cycle and atmospheric environment on Earth with interactions between the atmosphere, ocean, sea ice, and land.

• KOREAN JOURNAL OF CROP SCIENCE
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• v.67 no.1
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• pp.41-52
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• 2022

As a cultivar of Korean wheat, 'Keumgang' wheat variety has a fast growth period and can be grown stably. Hexaploid wheat (Triticum aestivum) has moderately high salt tolerance compared to tetraploid wheat (Triticum turgidum L.). However, the molecular mechanisms related to salt tolerance of hexaploid wheat have not been elucidated yet. In this study, the candidate genes related to salt tolerance were identified by investigating the genes that are differently expressed in Keumgang variety and examining salt tolerant mutation '2020-s1340.'. A total of 85,771,537 reads were obtained after quality filtering using NextSeq 500 Illumina sequencing technology. A total of 23,634,438 reads were aligned with the NCBI Campala Lr22a pseudomolecule v5 reference genome (Triticum aestivum). A total of 282 differentially expressed genes (DEGs) were identified in the two Triticum aestivum materials. These DEGs have functions, including salt tolerance related traits such as 'wall-associated receptor kinase-like 8', 'cytochrome P450', '6-phosphofructokinase 2'. In addition, the identified DEGs were classified into three categories, including biological process, molecular function, cellular component using gene ontology analysis. These DEGs were enriched significantly for terms such as the 'copper ion transport', 'oxidation-reduction process', 'alternative oxidase activity'. These results, which were obtained using RNA-seq analysis, will improve our understanding of salt tolerance of wheat. Moreover, this study will be a useful resource for breeding wheat varieties with improved salt tolerance using molecular breeding technology.

• The Journal of Engineering Geology
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• v.31 no.4
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• pp.603-620
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• 2021

A land nodal seismic system was employed to acquire seismic reflection data using stand-alone cable-free receivers in a land-river area. Acquiring reliable data using this technology is very cost effective, as it avoids topographic problems in the deployment and collection of receivers. The land nodal airgun system deployed on the mouth of the Hyungsan River (in Pohang, Gyeongsangbuk Province) used airgun sources in the river and receivers on the riverbank, with subparallel source and receiver lines, approximately 120 m-spaced. Seismic data collected on the riverbank are characterized by a low signal-to-noise (S/N) and inconsistent reflection events. Most of the events are represented by hyperbola in the field records, including direct waves, guided waves, air waves, and Scholte surface waves, in contrast to the straight lines in the data collected conventionally where source and receiver lines are coincident. The processing strategy included enhancing the signal behind the low-frequency large-amplitude noise with a cascaded application of bandpass and f-k filters for the attenuation of air waves. Static time delays caused by the cross-offset distance between sources and receivers are corrected, with a focus on mapping the shallow reflections obscured by guided wave and air wave noise. A new time-distance equation and curve for direct and air waves are suggested for the correction of the static time delay caused by the cross-offset between source and receiver. Investigation of the minimum cross-offset gathers shows well-aligned shallow reflections around 200 ms after time-shift correction. This time-delay static correction based on the direct wave is found essential to improving the data from parallel source and receiver lines. Data acquisition and processing strategies developed in this study for land nodal airgun seismic systems will be readily applicable to seismic data from land-sea areas when high-resolution signal data becomes available in the future for investigation of shallow gas reservoirs, faults, and engineering designs for the development of coastal areas.

• Korean Journal of Clinical Laboratory Science
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• v.56 no.2
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• pp.147-155
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• 2024

Gallium-68-prostate-specific membrane antigen-11 (⁶⁸Ga-PSMA-11) is a positron emission tomography radiopharmaceutical that labels a Glu-urea-Lys-based ligand with ⁶⁸Ga, binding specifically to the PSMA. It is used widely for imaging recurrent prostate cancer and metastases. On the other hand, the preparation and quality control testing of ⁶⁸Ga-PSMA-11 in medical institutions takes over 60 minutes, limiting the daily capacity of ⁶⁸Ge/⁶⁸Ga generators. While the generator provides 1,110 MBq (30 mCi) nominally, its activity decreases over time, and the labeling yield declines irregularly. Consequently, additional preparations are needed, increasing radiation exposure for medical technicians, prolonging patient wait times, and necessitating production schedule adjustments. This study aimed to reduce the ⁶⁸Ga-PSMA-11 preparation time and optimize the automated synthesis system. By shortening the reaction time between ⁶⁸Ga and the PSMA-11 precursor and adjusting the number of purification steps, a faster and more cost-effective method was tested while maintaining quality. The final synthesis time was reduced from 30 to 20 minutes, meeting the standards for the HEPES content, residual solvent EtOH content, and radiochemical purity. This optimized procedure minimizes radiation exposure for medical technicians, reduces patient wait times, and maintains consistent production schedules, making it suitable for clinical application.