• Title/Summary/Keyword: M/M/1 model

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Long-term Bias of Internal Markers in Sheep and Goat Digestion Trials

  • De Carvalho, Gleidson Giordano Pinto;Garcia, Rasmo;Vieira Pires, Aureliano Jose;Silva, Roberio Rodrigues;Detmann, Edenio;Oliveira, Ronaldo Lopes;Ribeiro, Leandro Sampaio Oliveira
    • Asian-Australasian Journal of Animal Sciences
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    • v.26 no.1
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    • pp.65-71
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    • 2013
  • Two digestion trials, one with sheep and another with goats, were conducted to evaluate the long-term bias (LTB) of the indigestible dry matter (iDM), indigestible neutral detergent fiber (iNDF) and indigestible acid detergent fiber (iADF) internal markers. The study used eight Santa In$\hat{e}$s castrated male sheep (average body weight of 16.6 kg) distributed in two $4{\times}4$ Latin squares and eight Saanen castrated male goats (average body weight of 22.6 kg) distributed in two $4{\times}4$ Latin squares. The experiments were conducted simultaneously, and the animals were housed in 1.2 $m^2$ individual pens with wood-battened floors equipped with individual feeders and drinkers. The animals received isonitrogenous diets that were offered ad libitum and contained 14% crude protein and 70% sugar cane (with 0, 0.75, 1.5 or 2.25% CaO, in natural matter percentage), corrected with 1% urea and 30% concentrate. The experiment consisted of four experimental periods of 14 d each, with the feed, leftovers and feces sampled on the last four days of each period. The marker concentrations in the feed, leftovers and fecal samples were estimated by an in situ ruminal incubation procedure with a duration 240 h. The relationship between the intake and excretion of the markers was obtained by adjusting a simple linear regression model, independently from the treatment (diets) fixed effects and Latin squares. For both the sheep and goats, a complete recovery of the iDM and iNDF markers was observed (p>0.05), indicating the absence of LTB for these markers. However, the iADF was not completely recovered, exhibiting an LTB of -9.12% (p<0.05) in the sheep evaluation and -3.02% (p<0.05) in the goat evaluation.

The Effects of Jungchun-tang and Jungchuntanggagambang on Immune Cell & Serum IgE in BALF in a Rat Asthma Model (정천탕과 정천탕가감방이 알레르기 천식모델 흰쥐의 BALF내 면역세포 및 혈청 IgE에 미치는 영향)

  • 염종훈;정희재;정승기;이형구
    • The Journal of Korean Medicine
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    • v.24 no.1
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    • pp.169-180
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    • 2003
  • Background : Allergic asthma is thought to be mediated by $CD4^{+}$ T lymphocytes producing the Th2-associated cytokines. According to investigations of lung biopsies and respiratory secretions from patients, $CD4^{+}$ T cells and eosinophils are the main features of the inflammatory process. Object : This study aimed to find an inhibition effect on allergens induced by JCT (Jungchun-tang) and JCTG (Jungchuntanggagambang) through the change of $CD4^{+}$ T cells and $CD8^{+}$ T cells in BALF of rat, and to see the change of IgE m serum. Materials and Methods : Laboratory rats were primary sensitized with OA (ovalbumin); on day 1, rats of a control group and a sample group (SBP group) were systemically immunized by subcutaneous injection of 1mg OA and 300mg of A1(OH)3 in a total volume of 2 ml saline. The rats of the sample group were orally administered with an SBP water extract for 14 days after primary immunization. On day 14 after the systemic immunization, rats received local immunization by inhaling 0.9% saline aerosol containing 2%(wt/vol) OA. A day after local immunization, BAL fluid and serum were collected from the rats. Total cells, lymphocytes, $CD4^{+}$ T cells, $CD8^{+}$ T cells, and $CD4^{+}$/$CD8^{+}$ ratio in the BALF, and IgE level in serum were measured and evaluated. Results : L Total cell in BALF of rat : JCT was observed to be significantly reduced but JCTG had no significant difference in comparison with the control group. 2. Lymphocytes in BALF of rat : JCT and JCTG were observed to be significantly reduced in comparison with the control group. 3. $CD4^{+}$T cells in BALF of rat : JCT was observed to be more significantly reducing than JCTG in comparison with the control group. 4. $CD8^{+}$T cells in BALF of rat : JCT and JCTG were observed not to be significantly different than in the control group. 5. $CD4^{+}/CD8^{+}$ ratio in BALF of rat : JCT and JCTG were observed not to be significantly different than in the control group. 6. The IgE level in serum : JCT and JCTG were observed to be significantly reduced in comparison with the control group. Conclusion : This study shows that JCT inhibits allergen-induced specially select $CD4^{+}$T cell channel in BALF of rat.

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Analysis of Fire Direction and Pine Tree Survival using to Fire Scar formed in Tree Stem after forest Fire (산불발생 후 불자국을 이용한 소나무 생존 및 지형에 따른 산불의 방향 분석)

  • 채희문;이찬용
    • Korean Journal of Agricultural and Forest Meteorology
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    • v.5 no.1
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    • pp.30-35
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    • 2003
  • The study of the scars formed on the bark of pine trees damaged by forest fire was carried out in the burned area of Samchuk and Donghae in 2000. Fire scars were formed on the bark of trees when fire passed by the tree. Fire scarring is usually found on the windward and leeward sides of the tree. Fire spread was analyzed topographically using the fire scars formed at the tree stem. Fire spread was closely related to the shape, slope and direction of the forestland. Four fire direction types are classified according to the shapes of the forestland. The height of the fire scar was higher on the leeward side than on the windward side of the trees studied. The burnt area of the total bark of the tree was over 30% in dead trees and below 12% in living trees. The regression model of the burnt stem area using the height of the fire scar, the diameter of breast height and the height of tree was Y=-2.484${\times}$Height+0.04199${\times}$D.B.H-1.686${\times}$Windward+11.172${\times}$Leeward+23.432(r=0.936, F=409.968, P>0.0001).

Estimation of Growth Curve Parameters for Body Weight and Length in Miniature Pigs

  • Kang, Hyun Sung;Nam, Ki Chang;Cabling, Meriam M.;Lee, Myeong Seop;Choi, Te Jung;Yoon, Jong Taek;Seo, Kang Seok
    • Journal of Animal Science and Technology
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    • v.54 no.6
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    • pp.395-400
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    • 2012
  • This study was conducted to estimate the growth curve parameters for the body weight (BW) and body length (BL) of miniature pigs in Korea. Growth curve parameters were estimated through a nonlinear regression model using Gompertz, Logistic, and von Bertalanffy methods. A total of 25 piglets were measured monthly from birth up to 15 months of age to estimate both body weight and length. Results showed that the estimated average values for the body weight (body length) were 31.83 kg (58.77 cm) for the mature weight (A), 3.06 (1.74) for the growth ratio (${\beta}$), and 0.28 (0.52) for the maturing rate (${\kappa}$). Average inflection points showing maximum growth rate estimated each month for body weight were 3.97 kg and 11.70 cm, while for the body length were 1.06 kg and 21.61 cm. Moreover, the estimated maturation rates of the body weight and length for the group of Sire 1 were 0.22 and 0.40 respectively, whereas for the group of Sire 2 these values were 0.34 and 0.39. On the other hand, for the groups of Dam 1, Dam 2, and Dam 3, maturation rates for their body weights were 0.26, 0.28 and 0.33 respectively, while for their body lengths these values were 0.43, 0.37, and 0.38, respectively. The study also indicated a negative relationship between the values of mature weight and maturity rate for the body weight will result to a higher inflection point which is in contrast for the body length where results show that a positive relationship between the values of mature length and the maturity rate will result to a higher inflection point. Furthermore, the growth performance of miniature pig varies across stages but using these estimated growth curve parameters could improve the genetic traits of miniature pig.

Estimation of Genetic Parameters via Gibbs Sampler using Animal Model for Economic Traits in Pigs (Gibbs Sampler를 이용한 돼지 주요 경제형질의 유전모수 추정)

  • Cho, K.H.;Kim, M.J.;Kim, I.C.;Jeon, G.J.
    • Journal of Animal Science and Technology
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    • v.50 no.1
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    • pp.19-26
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    • 2008
  • Heritability and genetic correlation for growth traits in Duroc pig breed were estimated using Bayesian method via Gibbs sampling. The data set consisted of 3,526 performance records at National Institute of Animal Science. For estimating those parameters using Gibbs sampling, 5,000 cycles of ‘burn-in’ period were discarded among a total of 55,000 samples. Out of the remaining 50,000 samples, 5,000 estimates by each parameter were retained and used for analyses to avoid any correlation among adjacent samples. The growth traits considered in this study were average daily gain at 30kg(ADG1), average daily gain at 90kg(ADG2), backfat thickness(BF), days to 90kg(D90) and feed conversion ratio(FC). The estimated heritabilities and their standard deviation using Gibbs sampler were 0.43±0.04, 0.49±0.038, 0.31±0.040, 0.48±0.039 and 0.62±0.086, respectively. Genetic correlations were -0.02, -0.13, -0.55 and -0.15 between ADG1 with ADG2, BF, D90 and FC, respectively, 0.16, -0.73, -0.32 between ADG2 with BF, D90 and FC respectively, 0.01, -0.08 between BF with D90, FC, respectively, and 0.23 between D90 with FC.

Weed Emergence in Orchard and Comparison of Weeding Performance of Some Orchard-Herbicides (Single and Mixture Products) (과수원(果樹園)의 잡초발생(雜草發生)과 제초제유형(除草劑類型) (단제(單劑) 및 혼제(混劑))별(別) 살초특성(殺草特性)의 비교연구(比較硏究))

  • Guh, J.O.;Cho, Y.W.;Lee, Y.M.
    • Korean Journal of Weed Science
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    • v.6 no.1
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    • pp.85-96
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    • 1986
  • From the two differently located orchards (even-site with adult tree and slope-site with young tree), weed emergence and the effect of various orchard herbicides on them were comparatively experimented. Weed emergence was assessed in emergence frequency, biomass, relative frequency, and herbicide responses were checked with the variarions in the above weed emergence characters and the weeding values. Herbicides applied were paraquat, glyphosate, oxyfluorfen, napropamide and ustinex using the recommended rates, respectively. Weeds emerged were 7 life-forms, 23 families and 45 species. Among other families, weeds Umbelliferae, Commelinaceae, Gramineae and Polygonaceae couldn't classified in any similarly correlated cluster. However, according to "1-Q mode cluster analysis" of each herbicide performances, "paraquat or glyphosate" with "napropamide or oxyfluorfen" were selected as the most unrelated herbicide pairs expecting the best combination value in mixture model, respectively.

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Potential Ability of Traditional Korean Medical Tourism and Economic Valuation of Sasang Constitutional Typology Diagnosis from Foreigner's Perspective (외국인이 인식하는 한의학 의료관광의 가능성 및 사상체질진단 경제적 가치평가)

  • Kim, Hyoung-Soon;Lee, Hee-Seung;Cha, Byung-Hun;Joo, Jong-Cheon
    • Journal of Sasang Constitutional Medicine
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    • v.23 no.1
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    • pp.115-124
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    • 2011
  • 1. Objectives : This study aimed to provide practical insights on the development of traditional Korean medical tourism and maximize the satisfaction of foreign patients. The main objectives of this study were also to evaluate Sasang Constitutional Medicine(S.C.M.) diagnosis cost from foreigners' perspectives. 2. Methods : For this study, the data were collected from tourists to Korea between January 3, 2010 to February 20, 2010. The sample used in this study was mainly composed of Japanese, Chines and US/Canada, because they are the major national visitor origin group to Korea. The primary data were collected by questionnaire survey using a standardized instrument with a convenience sampling procedure, and efforts of the interviews involved an on-site, self-administrated questionnaire to those sitting or visiting tourist attractions. The total size of the sample was 276 of which 275 showed no missing value against the factors needed for final analysis and were for analysis as an effective sample. SPSS 13.0 for window was used to analyze the collected data on which descriptive statistics and the Limited Dependent(LIMDEP) 8.0 program was used in estimating the willingness-to-pay(WTP) for traditional Korean medical tourism through the Contingent Valuation Method(CVM). A dichotomous choice question form of a CVM was applied to estimating the value. 3. Results and Conclusion: 1. There was significant statistical relationship between attributes when considering medical tourism destination and socio-demographic profiles such as age group, nationality, educational level and occupation. 2. In the level of recognition on Korean medicine, north Americans showed low level of recognition compared to other nationalities. In addition, in terms of age group, 20's and 30's showed low level of recognition on Korean medicine, 3. In relation to the level of interest on Korean medicine, Japanese respondents had higher interesting level on Korean medicine. Also singles had higher level of interest. 4. Regarding preferred Korean medical treatment program, there found significant statistical relationship between Korean medical treatment program and socio-demographic characteristics. 5. The estimating result of the logit model showed that the variables affecting the WTP for Sasang Constitutional medicine diagnosis were offered price and potential ability of medical tourism destination. 6. In relation to WTP for Sasang Constitutional medicine diagnosis, Japanese respondents showed a WTP of USD 62.69 and Chinese respondents showed USD 57.09. On the other hands, respondents from north America and other countries showed a WTP of USD 65.50. In conclusion, from this study, the results found that the opportunities in tradition Korean medical tourism are immense and the possible rewards are numerous. It is time to continue to promote 'Sasang Constitutional medicine' and make the Korean medical tourism programs considering on nationalities, age group, gender and WTP.

Dependency of Phonon-limited Electron Mobility on Si Thickness in Strained SGOI (Silicon Germanium on Insulator) n-MOSFET (Strained SGOI n-MOSFET에서의 phonon-limited전자이동도의 Si두께 의존성)

  • Shim Tae-Hun;Park Jea-Gun
    • Journal of the Institute of Electronics Engineers of Korea SD
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    • v.42 no.9 s.339
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    • pp.9-18
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    • 2005
  • To make high-performance, low-power transistors beyond the technology node of 60 nm complementary metal-oxide-semiconductor field-effect transistors(C-MOSFETs) possible, the effect of electron mobility of the thickness of strained Si grown on a relaxed SiGe/SiO2/Si was investigated from the viewpoint of mobility enhancement via two approaches. First the parameters for the inter-valley phonon scattering model were optimized. Second, theoretical calculation of the electronic states of the two-fold and four-fold valleys in the strained Si inversion layer were performed, including such characteristics as the energy band diagrams, electron populations, electron concentrations, phonon scattering rate, and phonon-limited electron mobility. The electron mobility in an silicon germanium on insulator(SGOI) n-MOSFET was observed to be about 1.5 to 1.7 times higher than that of a conventional silicon on insulator(SOI) n-MOSFET over the whole range of Si thickness in the SOI structure. This trend was good consistent with our experimental results. In Particular, it was observed that when the strained Si thickness was decreased below 10 nm, the phonon-limited electron mobility in an SGOI n-MOSFT with a Si channel thickness of less than 6 nm differed significantly from that of the conventional SOI n-MOSFET. It can be attributed this difference that some electrons in the strained SGOI n-MOSFET inversion layer tunnelled into the SiGe layer, whereas carrier confinement occurred in the conventional SOI n-MOSFET. In addition, we confirmed that in the Si thickness range of from 10 nm to 3 nm the Phonon-limited electron mobility in an SGOI n-MOSFET was governed by the inter-valley Phonon scattering rate. This result indicates that a fully depleted C-MOSFET with a channel length of less than 15 m should be fabricated on an strained Si SGOI structure in order to obtain a higher drain current.

Luteinizing hormone beta gene polymorphism and its effect on semen quality traits and luteinizing hormone concentrations in Murrah buffalo bulls

  • Reen, Jagish Kour;Kerekoppa, Ramesha;Deginal, Revanasiddu;Ahirwar, Maneesh Kumar;Kannegundla, Uday;Chandra, Satish;Palat, Divya;Das, Dayal Nitai;Kataktalware, Mukund Amritrao;Jeyakumar, Sakthivel;Isloor, Shri krishna
    • Asian-Australasian Journal of Animal Sciences
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    • v.31 no.8
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    • pp.1119-1126
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    • 2018
  • Objective: Present investigation was aimed to study the Single Nucleotide Variants of the luteinizing hormone beta ($LH{\beta}$) gene and to analyze their association with the semen quality (fresh and post-thawed frozen semen) and luteinizing hormone (LH) concentrations in Murrah buffalo bulls. Methods: Polymerase chain reaction-single stranded conformational polymorphism (PCR-SSCP) and Sanger sequencing method is used to study genetic variability in $LH{\beta}$ gene. LH assay was carried out using enzyme-linked immunosorbent assay method. A fixed general linear model was used to analyze association of single nucleotide polymorphism (SNP) of $LH{\beta}$ gene with semen quality in 109 and LH concentrations in 80 Murrah bulls. Results: $LH{\beta}$ gene was found to be polymorphic. Total six SNPs were identified in $LH{\beta}$ gene g C356090A, g C356113T, g A356701G, g G355869A, g G356330C, and g G356606T. Single Stranded Conformational Polymorphism variants of pattern 2 of exon 1+pattern 2 of exon 2+pattern 1 of exon 3 had highly significant (p<0.01) effect on sperm concentration (million/mL), percent mass motility, acrosome integrity and membrane integrity in fresh and frozen semen whereas significant (p<0.05) effect was observed on percent live spermatozoa. SSCP variants of pattern 2 of exon 1+pattern 2 of exon 2+pattern 1 of exon 3 had highly significant (p<0.01) effect on luteinizing hormone concentrations too. Conclusion: The observed association between SSCP variants of $LH{\beta}$ gene with semen quality parameters and LH concentrations indicated the possibilities of using $LH{\beta}$ as a candidate gene for identification of markers for semen quality traits and LH concentrations in Murrah buffaloes.

Electrical Transport Properties of La2/3TiO2.84 Ceramic (La2/3TiO2.84 세라믹스의 전기전도특성)

  • Jung, Woo-Hwan
    • Journal of the Korean Ceramic Society
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    • v.41 no.11
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    • pp.858-863
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    • 2004
  • The thermoelectric power, dc conductivity and magnetic properties of the cubic L $a_{2}$ 3/Ti $O_{2.84}$ were investigated. The thermoelectric power was negative below 350 K. The measured thermoelectric power of L $a_{2}$ 3/Ti $O_{2.84}$ increased linearly with temperature, in agreement with model proposed by Emin and Wood, and was represented by A+BT. Temperature dependence indicates that the charge carrier in this material is a small polaron. L $a_{2}$ 3/Ti $O_{2.84}$ exhibited a cross over from variable range hopping to small polaron hopping conduction at a characteristic temperature well below room temperature. The low temperature do conduction mechanism in L $a_{2}$ 3/Ti $O_{2.84}$ was analyzed using Mott's approach. Mott parameter analysis gave values for the density of state at Fermi level [N( $E_{F}$)] = 3.18${\times}$10$^{20}$ c $m^{-3}$ e $V^{-1}$ . The disorder energy ( $W_{d}$) was found to be 0.93 eV, However, it was noted that the value of the disorder energy was much higher than the high temperature activation energy. The exist linear relation between log($\sigma$T)와 1/T in the range of 200 to 300 K, the activation energy for small polaron hopping was 0.15 eV.