• Journal of Korean Public Health Nursing
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• v.32 no.3
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• pp.388-399
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• 2018

Purpose: The aim of this qualitative study was to identify the experiences of smoking and smoking cessation in out-of-school youth. Methods: The participants were 12 out-of-school youths belonging the Youth support Center located in A and B area. The data were collected from January 8 to 15, 2018, using a FGI(Focus Group Interview). The main sub-domains of the experiences of smoking and smoking cessation in out-of-school youth by 7 questions were categorized from the intrapersonal, interpersonal, organizational, and community factors in ecological model. Results: The motivation, continuity, disadvantage of smoking experiences of out-of-school youth were analyzed in 10 sub-domains (curiosity, friend's invitation, mood of adapted group, habit, relieving stress, providing breaks, friendship, physical damage, loss of money, a bad sight of smoker). The reason, difficulty, advantage, reason for restarting smoking cessation experiences of out-of-school youth were analyzed in 15 sub-domains (physical damage, for future hope, invitation of others, influence of family, weight gain, emotional stress, worsening friendship, improvement physical condition, saving money, better relationships, not with bad friends, withdrawal, smoking of friends, drinking, separated a lover). Conclusion: Based on the results, it is expected that a Specialized Smoking Cessation Education Program will be developed for out-of-school youth's health activities in ecological factors.

• Journal of Environmental Science International
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• v.32 no.10
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• pp.723-729
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• 2023

Parkinson's disease (PD) is the second most common neurodegenerative disorder, characterized by dopaminergic neuronal loss in the substantia nigra, resulting in reduced dopamine levels and consequent motor dysfunction. Genetic and environmental factors contribute to oxidative stress in PD. Cicadidae Periostracum (CP), a traditional Korean medicine, has shown neuroprotective effects against MPTP-induced neurotoxicity in PD. However, its effects on the 6-hydroxydopamine (6-OHDA) model have not been established. This study examined CP's effects on a 6-OHDA-induced PD model. CP protected against 6-OHDA damage in both in vitro and in vivo studies. Furthermore, CP reduced the production of reactive oxygen species, inhibited apoptosis, preserved dopamine levels, protected tyrosine hydroxylase in the substantia nigra, and improved motor function. These findings suggest that CP may delay PD progression by maintaining the redox balance.

• Journal of the Korea Academia-Industrial cooperation Society
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• v.22 no.2
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• pp.685-693
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• 2021

This study examined the fire risk of the region in Goyang City using the spatial information data of buildings. The economic damage by industry was assessed according to the probability of fire risk. The study area was confined to Goyang-si, Gyeonggi-do, and the same fire risk reduction rate was applied to each region for the convenience of analysis. The possibility of fire was derived based on the buildings' density and usage in the area by National GIS building-integrated information standard data. The calculation of economic damage by industry in Goyang City due to the fire risk was calculated by combining the Goyang-si industry-related model produced by matching with 30 industrial categories in Input-Output Statistics of Korea Bank and 20 industrial categories in the Goyang-si business survey and the possibility of fire. The basic scenario of production impossibility during six months and business loss due to fire was established and analyzed based on the supply model. The analysis showed that Ilsan-dong-gu, Ilsan-seo-gu, and Deokyang-gu suffered the most economic damage. The "electricity, gas, steam, and water business" showed the greatest loss by industry.

• Transactions of Materials Processing
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• v.22 no.4
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• pp.183-188
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• 2013

Scroll compressors are widely used in air conditioning systems and in automobiles due to their low pressure loss, minimal vibrations, and light-weight. Open-die forging with back pressure is used to forge the rotating scroll, and it requires special care since the forging die can be severely damaged at the fixed end of the spiral cavity similar to a fracture of a cantilever beam. To overcome the inevitable weakness of the forging die due to such damage, an innovative design is necessary. In this study, structural analysis using the finite element method was conducted to determine the reason for the fracture of the forging die. A novel design to avoid stress concentrations and vertical deflection, causing serious damage to the die, is suggested.

• Proceedings of the Korean Institute of Information and Commucation Sciences Conference
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• 2014.05a
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• pp.273-276
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• 2014

In 2014, the leakage of personal information from 3 credit card companies resulted in divulging approximately 10,000 customers' personal information. Although the credit card companies concluded that there was no secondary loss due to the leakage of personal information, secondary financial losses resulting from the leakage of personal information currently occur. In particular, hackers who employ smishing masquerade acquaintances by using the divulged personal information to ask payment for Ms. Kim's Sochi Olympics legal processing or exposed traffic violations. The hackers cause secondary financial losses through smartphones. This study aims to conduct a forensic analysis of smishing incidents in smartphones through the leakage of personal information, and to make a forensic analysis of financial losses due to the smishing incidents.

• Corrosion Science and Technology
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• v.21 no.2
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• pp.138-146
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• 2022

The cavitation and potentiodynamic polarization experiments were conducted simultaneously to investigate the effect of cavitation amplitude on the super austenitic stainless steel (UNS N08367) electrochemical behavior in seawater. The results of the potentiodynamic polarization experiment under cavitation condition showed that the corrosion current density increased with cavitation amplitude increase. Above oxygen evolution potential, the current density in a static condition was the largest because the anodic dissolution reaction by intergranular corrosion was promoted. In the static condition, intergranular corrosion was mainly observed. However, damage caused by erosion was observed in the cavitation environment. The micro-jet generated by cavity collapse destroyed the corrosion product and promoted the repassivation. So, weight loss occurred the most in static conditions. After the experiment, wave patterns were formed on the surface due to the compressive residual stress caused by the impact pressure of the cavity. Surface hardness was improved by the water cavitation peening effect, and the hardness value was the highest at 30 ㎛ amplitude. UNS N08367 with excellent mechanical performance due to its high hardness showed that cavitation inhibited corrosion damage.

• Biomolecules & Therapeutics
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• v.31 no.2
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• pp.148-160
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• 2023

Depression is a neuropsychiatric disorder associated with persistent stress and disruption of neuronal function. Persistent stress causes neuronal atrophy, including loss of synapses and reduced size of the hippocampus and prefrontal cortex. These alterations are associated with neural dysfunction, including mood disturbances, cognitive impairment, and behavioral changes. Synaptic plasticity is the fundamental function of neural networks in response to various stimuli and acts by reorganizing neuronal structure, function, and connections from the molecular to the behavioral level. In this review, we describe the alterations in synaptic plasticity as underlying pathological mechanisms for depression in animal models and humans. We further elaborate on the significance of phytochemicals as bioactive agents that can positively modulate stress-induced, aberrant synaptic activity. Bioactive agents, including flavonoids, terpenes, saponins, and lignans, have been reported to upregulate brain-derived neurotrophic factor expression and release, suppress neuronal loss, and activate the relevant signaling pathways, including TrkB, ERK, Akt, and mTOR pathways, resulting in increased spine maturation and synaptic numbers in the neuronal cells and in the brains of stressed animals. In clinical trials, phytochemical usage is regarded as safe and well-tolerated for suppressing stress-related parameters in patients with depression. Thus, intake of phytochemicals with safe and active effects on synaptic plasticity may be a strategy for preventing neuronal damage and alleviating depression in a stressful life.

• Asian-Australasian Journal of Animal Sciences
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• v.17 no.7
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• pp.1000-1006
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• 2004

Selenium and vitamin E are micronutrients essential for normal health and maintenance in poultry. They are necessary in preventing free radical damage to phospholipid membranes, enzymes and other important molecules. Two experiments were conducted in a semi-commercial environment to examine the effect of Se source and vitamin E level in diet on broiler performance and meat quality. Increasing vitamin E from 50 IU to 100 IU did not affect growth performance of broilers although the 24 h drip-loss was tended to be reduced (p=0.06). There was an interaction between vitamin E and the source of Se in glutathione peroxidase activity (GSH-Px) and Se concentration in excreta. Increasing vitamin E from 50 IU to 100 IU elevated GSH-Px and Se concentration in excreta by 42 IU/g Hb and 0.9 ppm for the organic Se group, respectively, but reduced GSH-Px and Se concentration in excreta by 16 IU/g Hb and 1.3 ppm for inorganic group, respectively. Vitamin E played no role in the feather coverage of the birds when scored on day 37. Organic Se is more effective in improving feather score and 24 h drip-loss, with a markedly higher deposition rate in breast muscle and a lower excretion rate in the excreta (p<0.05) compared to the inorganic Se source. Both vitamin E and the source of Se did not affect (p>0.05) the energy utilisation by birds.

• Biomolecules & Therapeutics
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• v.22 no.1
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• pp.47-54
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• 2014

The present study was aimed to evaluate the antioxidant defense system of cinnamaldehyde in normal, diabetic rats and its possible protection of pancreatic ${\beta}$-cells against its gradual loss under diabetic conditions. In vitro free radical scavenging effect of cinnamaldehyde was determined using DPPH (1,1-diphenyl-2-dipicrylhydrazyl), superoxide radical, and nitric oxide radical. Streptozotocin (STZ) diabetic rats were orally administered with cinnamaldehyde at concentrations of 5, 10 and 20 mg/kg body weight for 45 days. At the end of the experiment, the levels of plasma lipid peroxides and antioxidants such as vitamin C, vitamin E, ceruloplasmin, catalase, superoxide dismutase, reduced glutathione and glutathione peroxidase were determined. A significant increase in the levels of plasma glucose, vitamin E, ceruloplasmin, and lipid peroxides and significant decrease in the levels of plasma insulin and reduced glutathione were observed in the diabetic rats. Also the activities of pancreatic antioxidant enzymes were altered in the STZ-induced diabetic rats. The altered enzyme activities were reverted to near-normal levels after treatment with cinnamaldehyde and glibenclamide. Histopathological studies also revealed a protective effect of cinnamaldehyde on pancreatic ${\beta}$-cells. Cinnamaldehyde enhances the antioxidant defense against reactive oxygen species produced under hyperglycemic conditions and thus protects pancreatic ${\beta}$-cells against their loss and exhibits antidiabetic properties.

• Wind and Structures
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• v.38 no.5
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• pp.355-366
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• 2024

Severe natural multi-hazard events can cause damage to infrastructure and economic losses of billions of dollars. The challenges of modeling these losses include dependency between hazards, cause and sequence of loss, and lack of available data. This paper presents and explores multi-hazard loss modeling in the context of the combined wind and rain vulnerability of mid/high-rise buildings during hurricane events. A component-based probabilistic vulnerability model provides the framework to test and contrast two different approaches to treat the multi-hazards: In one, the wind and rain hazard models are both decoupled from the vulnerability model. In the other, only the wind hazard is decoupled, while the rain hazard model is embedded into the vulnerability model. The paper presents the mathematical and conceptual development of each approach, example outputs from each for the same scenario, and a discussion of weaknesses and strengths of each approach.