• Title/Summary/Keyword: Loss Correlations

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Effects of Age and Type of Stimulus on the Cortical Auditory Evoked Potential in Healthy Malaysian Children

  • Mukari, Siti Zamratol-Mai Sarah;Umat, Cila;Chan, Soon Chien;Ali, Akmaliza;Maamor, Nashrah;Zakaria, Mohd Normani
    • Korean Journal of Audiology
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    • v.24 no.1
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    • pp.35-39
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    • 2020
  • Background and Objectives: The cortical auditory evoked potential (CAEP) is a useful objective test for diagnosing hearing loss and auditory disorders. Prior to its clinical applications in the pediatric population, the possible influences of fundamental variables on the CAEP should be studied. The aim of the present study was to determine the effects of age and type of stimulus on the CAEP waveforms. Subjects and Methods: Thirty-five healthy Malaysian children aged 4 to 12 years participated in this repeated-measures study. The CAEP waveforms were recorded from each child using a 1 kHz tone burst and the speech syllable /ba/. Latencies and amplitudes of P1, N1, and P2 peaks were analyzed accordingly. Results: Significant negative correlations were found between age and speech-evoked CAEP latency for each peak (p<0.05). However, no significant correlations were found between age and tone-evoked CAEP amplitudes and latencies (p>0.05). The speech syllable /ba/ produced a higher mean P1 amplitude than the 1 kHz tone burst (p=0.001). Conclusions: The CAEP latencies recorded with the speech syllable became shorter with age. While both tone-burst and speech stimuli were appropriate for recording the CAEP, significantly bigger amplitudes were found in speech-evoked CAEP. The preliminary normative CAEP data provided in the present study may be beneficial for clinical and research applications in Malaysian children.

Effects of Age and Type of Stimulus on the Cortical Auditory Evoked Potential in Healthy Malaysian Children

  • Mukari, Siti Zamratol-Mai Sarah;Umat, Cila;Chan, Soon Chien;Ali, Akmaliza;Maamor, Nashrah;Zakaria, Mohd Normani
    • Journal of Audiology & Otology
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    • v.24 no.1
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    • pp.35-39
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    • 2020
  • Background and Objectives: The cortical auditory evoked potential (CAEP) is a useful objective test for diagnosing hearing loss and auditory disorders. Prior to its clinical applications in the pediatric population, the possible influences of fundamental variables on the CAEP should be studied. The aim of the present study was to determine the effects of age and type of stimulus on the CAEP waveforms. Subjects and Methods: Thirty-five healthy Malaysian children aged 4 to 12 years participated in this repeated-measures study. The CAEP waveforms were recorded from each child using a 1 kHz tone burst and the speech syllable /ba/. Latencies and amplitudes of P1, N1, and P2 peaks were analyzed accordingly. Results: Significant negative correlations were found between age and speech-evoked CAEP latency for each peak (p<0.05). However, no significant correlations were found between age and tone-evoked CAEP amplitudes and latencies (p>0.05). The speech syllable /ba/ produced a higher mean P1 amplitude than the 1 kHz tone burst (p=0.001). Conclusions: The CAEP latencies recorded with the speech syllable became shorter with age. While both tone-burst and speech stimuli were appropriate for recording the CAEP, significantly bigger amplitudes were found in speech-evoked CAEP. The preliminary normative CAEP data provided in the present study may be beneficial for clinical and research applications in Malaysian children.

Experimental Study on Pressure Loss of Flow Parallel to Rod Bundle with Spacer Grid (지지격자가 있는 봉다발과 축방향으로 평행한 유동의 압력손실에 관한 실험적 연구)

  • Lee, Chi-Young;Shin, Chang-Hwan;Park, Ju-Yong;In, Wang-Kee
    • Transactions of the Korean Society of Mechanical Engineers B
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    • v.36 no.7
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    • pp.689-695
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    • 2012
  • The friction factor in a rod bundle and the loss coefficient at a spacer grid were examined. As a test section, 25 smooth rods, 9.5 mm in diameter and 2000 mm in length, were prepared and installed in a $5{\times}5$ square array in a square channel. In this case, the P/D (Pitch-to-Diameter ratio) was 1.35. In this work, plain (i.e., no mixing vanes), split-vane, and hybrid-vane spacer grids were tested. In a bare rod bundle (i.e., no spacer grid), the measured friction factors were in good agreement with the previous correlations. Among the spacer grids tested, the hybrid-vane spacer grid presented the largest friction factor in the rod bundle and loss coefficient. This may be because of the flow pattern change induced by large relative plugging of the flow cross section and mixing vane geometry. At Re=$5{\times}10^5$, the predicted loss coefficients of plain, splitvane, and hybrid-vane spacer grids were approximately 0.79, 0.80, and 0.88, respectively.

Mutations in GJB2 as Major Causes of Autosomal Recessive Non-Syndromic Hearing Loss: First Report of c.299-300delAT Mutation in Kurdish Population of Iran

  • Azadegan-Dehkordi, Fatemeh;Bahrami, Tayyebe;Shirzad, Maryam;Karbasi, Gelareh;Yazdanpanahi, Nasrin;Farrokhi, Effat;Koohiyan, Mahbobeh;Tabatabaiefar, Mohammad Amin;Hashemzadeh-Chaleshtori, Morteza
    • Journal of Audiology & Otology
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    • v.23 no.1
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    • pp.20-26
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    • 2019
  • Background and Objectives: Autosomal recessive non-syndromic hearing loss (ARNSHL) with genetic origin is common (1/2000 births). ARNSHL can be associated with mutations in gap junction protein beta 2 (GJB2). To this end, this cohort investigation aimed to find the contribution of GJB2 gene mutations with the genotype-phenotype correlations in 45 ARNSHL cases in the Kurdish population. Subjects and Methods: Genomic DNA was extracted from a total of 45 ARNSHL families. The linkage analysis with 3 short tandem repeat markers linked to GJB2 was performed on 45 ARNSHL families. Only 9 of these families were linked to the DFNB1 locus. All the 45 families who took part were sequenced for confirmation linkage analysis (to perform a large project). Results: A total of three different mutations were determined. Two of which [c.35delG and c.-23+1G>A (IVS1+1G>A)] were previously reported but (c.299-300delAT) mutation was novel in the Kurdish population. The homozygous pathogenic mutations of GJB2 gene was observed in nine out of the 45 families (20%), also heterozygous genotype (c.35delG/N)+(c.-23+1G>A/c.-23+1G>A) were observed in 4/45 families (8.8%). The degree of hearing loss (HL) in patients with other mutations was less severe than patients with c.35delG homozygous mutation (p<0.001). Conclusions: Our data suggest that GJB2 mutations constitute 20% of the etiology of ARNSHL in Iran; moreover, the c.35delG mutation is the most common HL cause in the Kurdish population. Therefore, these mutations should be included in the molecular testing of HL in this population.

Mutations in GJB2 as Major Causes of Autosomal Recessive Non-Syndromic Hearing Loss: First Report of c.299-300delAT Mutation in Kurdish Population of Iran

  • Azadegan-Dehkordi, Fatemeh;Bahrami, Tayyebe;Shirzad, Maryam;Karbasi, Gelareh;Yazdanpanahi, Nasrin;Farrokhi, Effat;Koohiyan, Mahbobeh;Tabatabaiefar, Mohammad Amin;Hashemzadeh-Chaleshtori, Morteza
    • Korean Journal of Audiology
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    • v.23 no.1
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    • pp.20-26
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    • 2019
  • Background and Objectives: Autosomal recessive non-syndromic hearing loss (ARNSHL) with genetic origin is common (1/2000 births). ARNSHL can be associated with mutations in gap junction protein beta 2 (GJB2). To this end, this cohort investigation aimed to find the contribution of GJB2 gene mutations with the genotype-phenotype correlations in 45 ARNSHL cases in the Kurdish population. Subjects and Methods: Genomic DNA was extracted from a total of 45 ARNSHL families. The linkage analysis with 3 short tandem repeat markers linked to GJB2 was performed on 45 ARNSHL families. Only 9 of these families were linked to the DFNB1 locus. All the 45 families who took part were sequenced for confirmation linkage analysis (to perform a large project). Results: A total of three different mutations were determined. Two of which [c.35delG and c.-23+1G>A (IVS1+1G>A)] were previously reported but (c.299-300delAT) mutation was novel in the Kurdish population. The homozygous pathogenic mutations of GJB2 gene was observed in nine out of the 45 families (20%), also heterozygous genotype (c.35delG/N)+(c.-23+1G>A/c.-23+1G>A) were observed in 4/45 families (8.8%). The degree of hearing loss (HL) in patients with other mutations was less severe than patients with c.35delG homozygous mutation (p<0.001). Conclusions: Our data suggest that GJB2 mutations constitute 20% of the etiology of ARNSHL in Iran; moreover, the c.35delG mutation is the most common HL cause in the Kurdish population. Therefore, these mutations should be included in the molecular testing of HL in this population.

Element Dispersion by the Wallrock Alteration of Janggun Lead-Zinc-Silver Deposit (장군 연-아연-은 광상의 모암변질에 따른 원소분산)

  • Yoo, Bong Chul
    • Economic and Environmental Geology
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    • v.45 no.6
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    • pp.623-641
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    • 2012
  • The Janggun lead-zinc-silver deposit is hydrothermal-metasomatic deposit. We have sampled wallrock, hydrother-maly-altered rock and lead-zinc-silver ore vein to study the element dispersion during wallrock alteration. The hydrothermal alteration that is remarkably recognized at this deposit consists of rhodochrositization and dolomitization. Wallrock is dolomite and limestone that consisit of calcite, dolomite, quartz, phlogopite and biotite. Rhodochrosite zone occurs near lead-zinc-silver ore vein and include mainly rhodochrosite with amounts of calcite, dolomite, kutnahorite, arsenopyrite, pyrite, chalcopyrite, sphalerite, galena and stannite. Dolomite zone occurs far from lead-zinc-silver ore vein and is composed of mainly dolomite and minor calcite, rhodochrosite, pyrite, sphalerite, chalcopyrite, galena and stannite. The correlation coefficients among major, trace and rare earth elements during wallrock alteration show high positive correlations(dolomite and limestone = $Fe_2O_3(T)$/MnO, Ga/MnO and Rb/MnO), high negative correlations(dolomite = MgO/MnO, CaO/MnO, $CO_2$/MnO, Sr/MnO; limestone = CaO/MnO, Sr/MnO). Remarkable gain elements during wallrock alteration are $Fe_2O_3(T)$, MnO, As, Au, Cd, Cu, Ga, Pb, Rb, Sb, Sc, Sn and Zn. Remarkable loss elements are CaO, $CO_2$, MgO and Sr. Therefore, elements(CaO, $CO_2$, $Fe_2O_3(T)$, MgO, MnO, Ga, Pb, Rb, Sb, Sn, Sr and Zn) represent a potential tools for exploration in hydrothermal-metasomatic lead-zinc-silver deposits.

Factors Affecting Bone Mineral Status of Premenopausal Women (폐경 전 여성의 골밀도에 영향을 미치는 요인분석)

  • 오세인;이행신;이미숙;김초일;권인순;박상철
    • Korean Journal of Community Nutrition
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    • v.8 no.6
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    • pp.927-937
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    • 2003
  • This study was conducted to investigate dietary and other factors affecting bone mineral density (BMD) in Korean premenopausal women. Seventy-eight premenopausal women who visited the Health Promotion Center for health examinations volunteered to participate in this study. They were divided into two groups according to their bone status as shown by their T-scores: a non-osteoporotic group and a osteoporotic group. The results are as follows: The mean BMDs of the lumbar spine and femoral neck were 1.21$\pm$0.02$g/cm^2$ and 0.97$\pm$0.04$g/cm^2$, respectively. The BMD levels of the osteoporotic group were significantly lower than those of the non-osteoporotic group (p<0.001, respectively). The heights of the women in the osteoporotic group were significantly lower than those of the non-osteoporotic group (p<0.01) however, their body weights did not show any significant differences although they tended to be lower. The mean daily intake of energy was 1720$\pm$52㎉. When the nutrient intake was compared with the Korean recommended dietary allowances (RDA), calcium, Fe, vitamin A and riboflavin intakes were lower than the RDA. Their was no significant difference in the nutrient intake of the non-osteoporotic group and osteoporotic group except for the intakes of protein, fat and niacin. Their was no significant difference between the non-osteoporotic group and the osteoporotic group and all were within the normal range. However, the serum alkaline phosphatase level of the osteoporotic group was significantly higher than that of the non-osteoporotic group (p<0.001). Height measurements showed positive correlations with lumbar spine bone mineral density (LBMD, r=0.332, p<0.01) however there was no correlation with femoral neck bone mineral density (NBMD). Age, age at menarche, body weight, body mass index (BMI) and obesity showed no correlation with BMD. The BMD of the lumbar spine was significantly and positively related to the intake of niacin and vitamin C (r=0.236, p<0.05; r=0.274, p<0.05). Serum levels of calcium and phosphorus showed negative correlations with LBMD (r=-0.698, p=0.0001, r=-0.503, p=0.0001, respectively). The results suggested that the BMD of the lumbar spine was positively related to the intake of niacin and vitamin C in premenopausal women. Therefore, this study confirmed that one of the most effective ways to minimize bone loss would be have a higher intake of niacin and vitamin C rich foods and engaging habitually in physical activity may have a beneficial effect on BMD in the Premenopausal Period.

Studies on Press Drying and Dynamic Elastic Modulus of Plywood Treated with Boric Acid (붕산처리(硼酸處理) 합판(合板)의 열판건조(熱板乾燥) 및 동적(動的) 탄성율(彈性率)에 관(關)한 연구(硏究))

  • Kim, Jong-Man
    • Journal of the Korean Wood Science and Technology
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    • v.15 no.3
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    • pp.56-67
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    • 1987
  • Plywoods used for construction as a decorative interior material are inflammable and can make fire accidents, causing destruction of human life and property. Therefore, it is indeed required to make fire-retardant treated plywood. In this study, 3.7mm yellow meranti plywoods were soaked in 18% boric acid solutions and tap water by hot-cold bath for 1/2, 2/2, 4/2, 6/2 hours and redrying of treated plywoods was carried out by press drying at the platen temperature of 110, 130, 160, $180^{\circ}C$ and then it was conducted to investigate solution absorption, drying rates, dynamic young's modulus. specific gravity and fire-retardant factors such as burning point, flame spread length. flame exhausted time, back side carbonized area and weight loss by treating time, treating solutions and platen temperature. The results are as follows; 1. When plywood was impregnated with the hot bath temperature of $70^{\circ}C$ for 1. 2, 4, 6 hours and the cold bath temperature of $15^{\circ}C$ for 2 hours respectively, retentions of boric acid were 1.565, l.597, 1.643, 1.709kg/$(30cm)^3$ and all of them exceeded the minimum retention [1.125kg/$(30cm)^3$] even in the shortest treatment. 2. In hot-cold bath method for 1/2 hours, the drying rates of treated plywood remarkably increased with the extension of platen temperature of 110, 130, 160, $180^{\circ}C$ and the values of boric acid treated plywood were 5.900, 10.196, 45.42, 54.958m.c%/min and the values of water treated plywood were 6.014, 12.373, 46.520, 55.730m.c%/min and drying rates of water treated plywood were faster than those of boric acid treated plywood. 3. The values of boric acid treated plywoods in dynamic young's modulus were widely higher than those of water treated plywoods. And it can be observed that there were highly significant differences for treating time between dynamic young's modulus, and the values of boric acid plywoods increased with the extension of treating time but on the contrary water treated plywoods were decreased values with prolonged time 4. It was observed that there were highly significant differences for platen temperature between dynamic young's modulus. When the values of water treated plywoods in dyna nic young's modulus were abruptly decreased according to the rise of platen temperature. boric acid treated plywoods showed rather increased values at $160^{\circ}C$ of platen temperature. And in 2- way interactions, there were also highly significant for dynamic young's modulus between treating time x treating solutions and platen temperature x treating solutions. 5. Correlation coefficients of fire-retardant factors were shown in table 5. It could be recognized that there were close correlations between the treating solutions and burning point, flame spread length, back side carbonized area, flame exhausted time and weight loss, but there was no correlation between fire-retardant factors and treating time and platen temperature. 6. From table 6, it can be observed that there were highly significant differences for burning point, flame spread length, flame exhausted time, back side carbonized area, weight loss between treating solutions. And in 2-way interactions, there were highly significant for burning point, flame spread length, weight loss between treating time $\times$ treating solutions.

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Choosing quality indicators for quality prediction of egg in circulation (계란의 유통 중 품질예측을 위한 품질지표 선정)

  • Lee, Hye-Ok;Kim, Ji-Young;Kim, Byeong-Sam
    • Food Science and Preservation
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    • v.21 no.5
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    • pp.609-617
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    • 2014
  • This study was conducted to identify quality indicators of the freshness of chicken eggs circulating in domestic markets. We first stored freshly-laid eggs at temperatures of 0, 10, 20, and $30^{\circ}C$, investigated their weight-loss rate, specific gravity, color, york index, albumen index, Haugh unit (HU), pH, and sensory evaluation, and finally analyzed the correlation between each quality characteristic and the sensory preference. At all the storage temperatures, the quality characteristics of the weight-loss rate, specific gravity, yolk index, albumen index, and HU showed significant correlations (p<0.05) with the preference. In particular, the temperature-dependent correlation between the quality characteristics and the sensory preference was significantly higher with increasing storage temperatures and weight-loss rates (r = -0.78; r = -0.93; r = -0.95; and r = -0.99), albumen index (r = 0.66; r = 0.89; r = 0.89; and r = 0.93), and HU values (r = 0.64; r = 0.92; r = 0.96; and r = 0.98) at 0, 10, 20, and $30^{\circ}C$, respectively (p<0.01). The Color and pH examinations yielded disparate results, and further research is needed to determine the methods of using the characteristics as quality indicators. We believe that the changes in the weight-loss rate, specific gravity, yolk index, albumen index, and HU are adequate quality indicators of the freshness of egg in circulation.

Psychological Characteristics and Life Satisfaction of the Elderly -Focusing on Gwangju Metropolitan City- (노인의 심리적 특성과 삶의 만족도 분석 -광주광역시를 중심으로-)

  • Chon, Lee-sang;Cho, Hong-joong
    • Journal of the Korea Convergence Society
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    • v.12 no.6
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    • pp.225-232
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    • 2021
  • The purpose of this study is to identify the psychological characteristics of the elderly and to investigate the variables that affect the life satisfaction of the elderly. To achieve this purpose, psychological characteristics such as self-esteem, alienation, loss, and depression were selected. A survey was conducted on the elderly living in Gwangju Metropolitan City. A total of 218 copies were collected and 203 copies were analyzed, excluding poor responses. To draw the results of the research, quantitative analysis was conducted through questionnaires, and SPSSWIN 21.0 statistical program was used as an analysis tool. The analysis methods were frequency and ratio analysis, technical statistical analysis, bivariate correlation analysis, and linear regression analysis. The results of the analysis are as follows: First, the relationship between the psychological characteristics of the elderly showed significant correlations among the self-esteem, alienation, loss, depression, and life satisfaction of the elderly. Second, for the elderly, alienation and depression had a negative effect on life satisfaction, and self-esteem had a positive effect on life satisfaction. However, loss did not have a significant effect on life satisfaction. In conclusion, it suggests that it is necessary to develop and operate policies and programs to improve self-esteem and reduce alienation and depression in order to improve the quality of life of the elderly.