• 산업경영시스템학회지
• /
• 제44권4호
• /
• pp.98-105
• /
• 2021

Using the frequency-based decomposition, I decompose the consumption growth to explain well-known patterns of stock returns in the Korean market. To be more specific, the consumption growth is decomposed by its half-life of shocks. The component over four years of half-life is called the business-cycle consumption component, and the components with half-lives under four years are short-run components. I compute the long-run and short-run components of stock excess returns as well and use component-by-component sensitivities to price stock portfolios. As a result, the business-cycle consumption risk with half-life of over four years is useful in explaining the cross-section of size-book-to-market portfolios and size-momentum portfolios in the Korean stock market. The short-run components have their own pricing abilities with mixed direction, so that the restricted one short-term factor model is rejected. The explanatory power with short- and long-run components is comparable to that of the Fama-French three-factor model. The components with one- to four-year half-lives are also helpful in explaining the returns. The results about the long-run components emphasize the importance of long-run component in consumption growth to explain the asset returns.

• Asian Pacific Journal of Cancer Prevention
• /
• 제13권11호
• /
• pp.5741-5746
• /
• 2012

Aim: Although preoperative chemoradiatherapy (CRT) has proven its benefits in terms of decreased toxicity, there is still a considerable amount of cases that do not receive postoperative CRT. Oncologists at different geographic locations still need to know the long-term effects of this treatment in order to manage patients successfully. The current paper reports on long-term quality of life (QOL) and late side effects after adjuvant CRT in rectal cancer patients from 5 centers in Anatolia. Methods: Rectal cancer patients treated with postoperative CRT with minimum 1-year follow-up and were in complete remission, were evaluated according to RTOG and LENT-SOMA scales. They were also asked to complete Turkish version of EORTC QLQ-C30 questionnaire and the CR-38 module. Each center participated with the required clinical data. Results: Two hundred and thirty patients with median age of 55 years participated and completed the study. Median follow-up time was 5 years. All patients received RT concomitant with chemotherapy. Common parameters that both increased functional health scales and yielded better symptom scores were long term interval after treatment and sphincter-saving surgery. In addition, surgery type and follow-up time were determined to be predictors of QOL scores and late toxicity grade. Conclusion: Postoperative CRT was found to have a great impact on the long term QOL and side effects in rectal cancer survivors. The factors that adversely affect these are abdominoperineal resection and shorter interval. The findings may encourage life-long follow-up and cooperation with patients, which should be mentioned during the initial counseling.

• Clinical and Experimental Pediatrics
• /
• 제46권12호
• /
• pp.1235-1241
• /
• 2003

목 적 : 현재 시중에 판매되고 있는 연무기 기종에 따라 그 성능이 다를 것으로 보고 제품 선택에 도움이 되고자 국내 시판중인 16가지 연무기 기종의 성능을 실험을 통하여 비교하였다. 방 법 : 16가지 연무기/압축기 제품(Pariboy Type 38/Long life, Pariboy Type N/Long life, Pariboy Type N/Salter 8900, Pariboy Type N/LC, Devilbiss pulmoaid-LT/Hudson, Devilbiss pulmoaid/Hudson, Mesmed neb-300/Own, San-up 3040/Hudson, Midas(Basic)/Own, AirJolie2/Hudson, Thomas 1127/Salter 8900, Noel NE-2000/Salter 8900, Omron CX3/Hudson, Chang Woo CWN-100/Salter 8900, Voyage/Mefar, ASI-Pro/Medel jet pluse)을 가지고 Mass output과 입자 크기를 측정하였다. Mass output은 생리식염수 4 mL를 2분간 분무 전, 후의 무게변화를 정밀 전자저울로 측정하였다. 동일한 방법으로 생리식염수 3 mL를 채워 실험하였다. 입자의 크기는 0.9% 생리식염수 4 mL를 채우고 5분간 작동하면서 laser diffraction법을 이용하여 측정하였다. 결 과 : 분당흡입량은 Pariboy type N/Long life이 0.184 mg/min로 가장 높은 값을 보였으며 0.019 mg/min로 가장 낮은 수치를 나타낸 Mesmed Neb-300/Own과는 약 9.6배의 차이를 보였다. Pariboy Type N/Long life이 Mass output이 0.68 mg/min로 가장 컸고 0.13 mg/min으로 가장 작은 수치를 보인 Mesmed-Neb/Own과는 5.2 배 차이가 있었다. 모든 제품은 5분간의 입자의 크기를 측정하였으나 검사시간 동안 입자크기의 차이는 보이지 않았다. $5{\mu}m$ 이하의 입자크기의 최대값은 64%였고 최소값의 연무기는 20%였다. MMAD는 Pariboy Type N/Long life이 $3.76{\mu}m$로 가장 작았으며 나머지 제품은 모두 $5{\mu}m$ 이상이었다. 결 론 : 시중에 판매되는 연무기들의 기능이 다양하므로 제품의 선택에 있어서 그 성능을 고려할 필요가 있다.

• Fisheries and Aquatic Sciences
• /
• 제13권1호
• /
• pp.56-62
• /
• 2010

To determine whether long double-stranded RNA (dsRNA) induces RNA interference and type I interferon (IFN) responses in fish, long dsRNAs encoding enhanced green fluorescent protein (EGFP), GFPuv, and polyinosinic-polycytidylic acid sequences were co-injected with an EGFP expressing plasmid, into rock bream (Oplegnathus fasciatus). We investigated the EGFP mRNA and protein levels, and the transcriptional responses of dsRNA-dependent protein kinase and Mx1 genes. Long dsRNAs were strong inducers of a type I IFN response in rock bream, resulting in nonspecific suppression of exogenous gene expression. Furthermore, sequence-specific knockdown of exogenous gene expression at the mRNA level was detected at an early phase (24 h). These results suggested that long dsRNA may inhibit exogenous gene expression through an early mRNA interference response and a later type I IFN response in fish.

• 한국노년학
• /
• 제30권4호
• /
• pp.1239-1261
• /
• 2010

본 연구는 장기간 노인(전문)병원 및 요양시설에서 생활하고 있는 뇌졸중 생존 노인들의 건강관련 삶의 질에 미치는 요인들이 무엇인지 규명함으로써 대상자들의 삶의 질 증진을 위한 사회복지 실천 방안들을 제언하고자 시행되었다. 연구 대상자는 충청지역 및 D 광역시 소재 노인(전문)병원 18곳과 요양시설 13곳에서 장기 입원(입소)하고 있는 55세 이상의 뇌졸중 생존 노인들이며 서베이 방법을 사용하여 직접면담조사를 실시하였다. 조사는 2008년 12월 16일부터 2009년 1월 17일까지 실시되었고, 총 328부의 설문지가 통계분석에 이용되었다. 연구결과 대상자들이 인지하고 있는 건강관련 삶의 질은 비교적 낮게 나타났고, 특히 건강관련 삶의 질을 구성하고 있는 하위 영역 중 사회적 관계 영역이 가장 낮게 나타났다. 투입된 독립변수들이 건강관련 삶의 질에 미치는 상대적 영향력은 '우울', '향후 경제적 부담감', '일상생활수행능력', '장애수용', '중복질환', '경제적 주부양자가 배우자인 경우'순으로 나타났다. 본 연구를 통해 장기재활 및 요양서비스를 이용하고 있는 뇌졸중 생존 노인들의 건강관련 삶의 질에 질병관련 요인뿐만 아니라 심리사회적 요인, 환경적 요인 모두 중요한 영향을 미치고 있다는 것이 규명되었고, 그 가운데서도 심리사회적 요인의 영향력이 제일 큰 것으로 밝혀졌다. 이를 바탕으로 노인의료복지시설에서 생활하고 있는 뇌졸중 생존 노인들의 삶의 질을 향상시키고 더 나아가 사회복지사들의 역량을 고취시킬 수 있는 사회복지 방안들이 논의되었다.

• 동아시아경상학회지
• /
• 제2권4호
• /
• pp.26-47
• /
• 2014

The paper examined effect of age cohort on life cycle financial planning. A total of 990 questionnaires were distributed with a 55.2% return rate. Seven hypotheses were analysed using hierarchical and ordinary regression analysis. The results revealed that age cohort variables made significant contribution to life cycle financial planning as well as personal orientation towards retirement planning, particularly the younger age cohort. Age cohorts do affect personal orientation towards retirement planning with the confidence level making a significant impact. Current financial resources do have a strong positive impact on consumption for all age cohorts. On the other hand, no significant effect was found between age cohorts and current financial resources but older age cohorts were relatively more significant predictors. The implication was that not only should their individual perceptions of financial planning become an increasingly important part of people's long-term commitment throughout their life-cycle, it must also assume the role as a self-directed life-long learning process, in view of the ever-changing and complicated financial environment.

• 한국신뢰성학회지:신뢰성응용연구
• /
• 제13권1호
• /
• pp.55-63
• /
• 2013

For a reliability assessment of large machinery parts, reliable data should be obtained from testing many samples for a long time. However, in case of testing these samples, testing cost is excessive; in case of life test for long time, power consumption is high; and in case of accelerated test by over load, very high cost is required to build the life testing device. Especially it is very frequent that the expensive device's life has ended during a accelerated test by over load. In this study, the design mechanism of the life testing device which excels in energy saving during the reliability test of large machinery parts has been introduced.

• 한국산학기술학회논문지
• /
• 제18권10호
• /
• pp.336-343
• /
• 2017

본 연구에서는 요양보호사의 감정노동, 직무관련 삶의 질, 서비스 질의 관계를 분석하였다. 연구대상은 전국의 장기요양시설에 근무하는 요양보호사 211명이며, 자기기입식 설문지를 활용하여 조사 하였다. 연구모형은 감정노동(표면행위, 내면행위)을 독립변수, 직무관련 삶의 질(공감만족, 공감피로)을 매개변수, 서비스 질을 종속변수로 구성하여 검증하였다. 모형의 적합성과 서비스 질에 영향을 미치는 각 요인의 직접효과, 간접효과를 검증한 결과 모형의 적합도는 적합한 수준이었으며, 감정노동 표면행위와 내면행위에서 서비스 질로 향하는 직접효과는 통계적으로 유의미하지 않는 것으로 나타났다. 그러나 직무관련 삶의 질을 매개하여 서비스 질에 영향을 미치는 총 효과는 통계적으로 유의미하였으며, 내면행위와 서비스질의 관계에서는 정적 상관관계, 표면행위와 서비스질의 관계는 부적 상관관계가 있음을 확인할 수 있었다. 서비스 질에 영향력이 가장 큰 변인은 직무관련 삶의 질(공감만족)이었다. 이 연구 결과를 토대로 요양보호사의 감정노동과 삶의 질에 대한 임상적, 학문적 관심을 환기시킬 필요성을 제안하였다.

• Molecules and Cells
• /
• 제41권2호
• /
• pp.134-139
• /
• 2018

Here, we report isolation of multiple long non-coding RNAs (lncRNAs) expressed tissue-specifically during murine embryogenesis. One of these, subsequently came to be known as Redrum, is expressed in erythropoietic cells in fetal liver and adult bone marrow. Redrum transcription is also detected during pregnancy in the spleen where extramedullary hematopoiesis takes place. In order to examine the function of Redrum in vivo, we generated a gene-targeted murine model and analyzed its embryonic and adult erythropoiesis. The homozygous mutant embryo showed no apparent deficiency or defect in erythropoiesis. Adult erythropoiesis in bone marrow and in the spleen during pregnancy likewise showed no detectable phenotype as red blood cells matured in normal fashion. The phenotype is in contrast to the reported function of Redrum in vitro, and our observation implies that Redrum plays in vivo an accessory or supplementary role whose loss is compatible with normal erythropoiesis.

• Molecules and Cells
• /
• 제44권3호
• /
• pp.160-167
• /
• 2021

The determinant factors of an organism's size during animal development have been explored from various angles but remain partially understood. In Caenorhabditis elegans, many genes affecting cuticle structure, cell growth, and proliferation have been identified to regulate the worm's overall morphology, including body size. While various mutations in those genes directly result in changes in the morphological phenotypes, there is still a need for established, clear, and distinct standards to determine the apparent abnormality in a worm's size and shape. In this study, we measured the body length, body width, terminal bulb length, and head size of mutant worms with reported Dumpy (Dpy), Small (Sma) or Long (Lon) phenotypes by plotting and comparing their respective ratios of various parameters. These results show that the Sma phenotypes are proportionally smaller overall with mild stoutness, and Dpy phenotypes are significantly stouter and have disproportionally small head size. This study provides a standard platform for determining morphological phenotypes designating and annotating mutants that exhibit body shape variations, defining the morphological phenotype of previously unexamined mutants.