• 대한족부족관절학회지
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• 제17권2호
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• pp.93-99
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• 2013

Purpose: Proximal metatarsal chevron osteotomy for hallux valgus is followed by significant amount of postoperative pain. Periarticular multimodal drug local injection can be an option for pain control. This study was attempted to evaluate the efficacy of the morphine as multimodal drug and to confirm the effect of periarticular multimodal drug local injection on controlling early postoperative pain. Materials and Methods: Between March 2012 and June 2012, 22 patients received proximal metatarsal chevron osteotomy for the correction of hallux valgus deformity. 10 patients (Group A) received periarticular injection of the test solution made with morphine, ropivacaine, ephinephrine and ketorolac. 12 patients (Group B) received periarticular injection of the test solution without morphine. The visual analog scale (VAS) was checked at 2, 4, 6, 8 hours, 1 day and 2 days each after surgery. Results: The VAS score at postoperative 2 hours to 1 day between two groups showed no significant difference, but the VAS score at postoperative 2 days was significantly higher in Group A compared to the VAS score of group B. The amount of additional pain control (tramadol HCL) between two groups showed no significant difference for 3 days after surgery. Conclusion: Periarticular multimodal drug local injection was effective in reducing pain after hallux valgus surgery regardless of mixing with morphine.

• 대한치과마취과학회지
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• 제10권1호
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• pp.1-6
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• 2010

Background: Articaine, commercially available in South Korea from 2004, is widely being used for dental treatments. In the surgical extraction of impacted mandibular third molars, one of the most common procedures in oral and maxillofacial surgery, the anesthetic efficacy of 4% articaine and 2% lidocaine, both with 1：100,000 epinephrine, was compared. Methods: A randomized double-blind clinical trial was conducted of 80 patients for bilateral surgical extraction of mandibular third molars with informed consents. One operator carried out the routine surgical procedures using local anesthetic 4% articaine or 2% lidocaine with the same concentration of vasoconstrictor. Latency, duration of anesthesia and the amount of anesthetic solution were recorded. A visual analog scale (VAS) was used to evaluate the intraoperative pain. Results: The pain VAS scores reported similar anesthetic effect with both local anesthetics. Not in the latency of anesthesia and the amount of anesthetic solution, statistically significant difference was found in the mean duration of anesthesia. Conclusions: It was concluded that 4% articaine could offer better or at least the same clinical feasibility compared to 2% lidocaine, particularly in terms of the duration of the local anesthesia for common dental treatments.

• The Journal of Korean Physical Therapy
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• 제10권1호
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• pp.1-6
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• 1998

효율적으로 국소마취를 유발시키는 procaine이온도입의 효과적인 농도를 조사하였다. 19세에서 34까지의 자원자 45명을 9명씩 무작위로 5군으로 나누어 배치하고, 각군 대상자의 오른쪽 전완 전면에 각각 $2\% (pH\;5.2H),\;4%(pH\;5.12),\;8\%(pH\;4.98),\;16\%(pH\; 4.72),\;32\%(pH\;4.52)$ 염산 procaine용액 2ml를 적신 $3.5\times3.5 cm$의 면패드를 대고 4mA로 10분간 양극 직류전류를 통전시켰다. 이온도입 직후부터 5분 간격으로 21 G주사침으로 이온도입부위를 1mm함몰되게 눌러 바늘로 찌르는 통증을 느낄 때까지 감각검사를 시행하여 국소마취지속시간을 측정하였다. Procaine의 농도에 따른 축소마취지속시간을 일원분산분석한 결과 유의한 차이를 보였으며 (F=5.83; df=4, 40; p<.001). 이를 사후검정한 결과 농도 $4\%$의 국소마취지속시간이 농도 $2\%,\;8\%,\;16\%,\;32\%$보다 유의하게 길었다 (p<.01). 또한 상관분석 결과 약물의 농도는 국소마취지속시간과 상관관계가 없었다 (r=-0.41, NS). 본 연구 결과 $4\%$ 농도의 염산 procaine 용액의 이온도입이 국소마취지속시간을 가장 길게 유지하여 $4\%$ 염산 procaine 용액이 이온도입에 가장 효과적인 농도였음을 알 수 있었다.

• 한국산학기술학회논문지
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• 제20권10호
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• pp.125-132
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• 2019

수중폭발로 인해 발생된 충격파에 노출된 유체(대부분 해수)는 유체장 내 압력과 속력 등의 물리적 변화에 따른 장력을 견딜 수 없으므로 캐비테이션(기포 또는 기공)이 발생하게 되고 이때 발생된 캐비테이션은 수중폭발의 연쇄 과정 중 구조물에 미치는 충격하중의 전달 환경을 변화시킨다. 폭발물과 구조물 간의 거리가 비교적 가까워 선체구조의 국부적 손상에 관심을 가지는 근거리 수중폭발연구에서 관심을 가지는 물리적 현상은 크게 3가지로 초기충격파 그리고 그것과 선체구조와의 상호작용, 국부 캐비테이션, 국부 캐비테이션 폐쇄 후 2차 충격파이다. 본 논문의 관심은 근거리 수중폭발에 따른 국소 캐비테이션이므로 수면과 해저로부터의 반사파는 고려하지 않는다. 유체와 구조에 관한 각각의 지배 방정식을 유도하고 이를 간단한 1차원 무한평판 문제에 적용, 수치적으로 해석하여 엄밀해와 비교해봄으로써 제안된 비연성 해석방법을 검증한다. 비연성 해석방법은 유체-구조 결합 해석방법보다 계산상 효율이 높으며 간단함에도 불구하고 상대적으로 높은 수준의 정확도를 얻을 수 있다는 점에서 유용하다. 본 논문을 통해 수중폭발과 같은 복잡한 물리적 상황에서의 유체-구조 상호작용 현상에 대한 이해와 실질적인 문제에 개념적 이해를 높이는 데 도움이 될 것이다.

• Architectural research
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• 제12권2호
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• pp.63-72
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• 2010

Affordable housing has been a critical issue in the face of global economy and notably formulated a crucial agenda of the housing policy. While each local government seriously considers many approaches to providing affordable housing, a unique and innovative way to address it at a community level is fully uncovered, particularly nonmetropolitan areas where resources for economic development are limited and vulnerable. The purpose of this study is to examine the mechanism of the provision of affordable housing for the elderly in nonmetropolitan areas. In doing so, this research investigates the housing development and delineates it as one viable solution that stimulates local communities. The affordable housing development, as a viable option to spur local development and vibrate community, is closely reviewed, and the factors to make it feasible are drawn. The findings indicate that it is widely recognized that keeping the elderly in the community positively contributes to maintaining a sustainable community. In fact, the idea of affordable housing development for middle-class elderly people is brought by one inspired long-time resident, and it is expedited by the consensus and cohesion of local community. The development stimulates local businesses in relation to housing, and all homes sold by the elderly moving in the new housing are available for young families. Also, the presence of affordable housing for the elderly who are able to independently live is extended to a picture of aging-in-place at a broader level.

• 토지주택연구
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• 제9권4호
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• pp.10-18
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• 2018

As the volatility increasement of the number of tourist, there was been controversy over supply-demand imbalance in hotel market. The purpose of this study is to analysis on determinants of hotel occupancy rate in Jeju Island. The quantitative method is based on cointegrating regression, using an empirical dataset with hotel from 2000 to 2017. The primary results of research is briefly summarized as follows; First, there are high relationship between total hotel occupancy rate and hotel occupancy of foreign tourist. The volatility of hotel occupancy is caused by foreigner user than local tourists though local tourist high propotion of hotel occupancy in Jeju Island. Second, hotel occupancy of local tourist has not relationship with demand and supply variables. Because some hotel users are not local tourists but local resident, and effects to other variables of hotel consumer trend, accommodation such as Guest house, Airbnb. Third, there are high relationship between foreign hotel occupancy rate and demand-supply variables. These research imply that total management of supply-demand is very important to seek stability of hotel occupancy rate in Jeju Island. Also it can provide a useful solution regarding mismatch problem between supply-demand as well as development the systematic forecasting model for hotel market participants.

• 대한기계학회논문집A
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• 제21권10호
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• pp.1598-1608
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• 1997

Based on the application of te theory of conjugate approximations and the Loubignac's iterative method in a local region, a method to improve the stress filed in a displacement-formulated finite element solution has been proposed. The validity of the proposed method has been tested through two examples : a thick cylinder under internal pressure loading and an infinite plate with a central circular hole subjected to uniaxial tension. As a result of analysis of the examples, it was found that the stress field obtained for the local region model by the proposed method approximates well for the whole domain model. In addition, it was found that because of a significant decrease in the computing time to obtain the improved stress field, the proposed method is efficient and useful for the detailed stress analysis in local regions.

• 전자공학회논문지C
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• 제35C권3호
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• pp.79-89
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• 1998

The Error Back-Propagation(EBP) algorithm is widely applied to train a multi-layer perceptron, which is a neural network model frequently used to solve complex problems such as pattern recognition, adaptive control, and global optimization. However, the EBP is basically a gradient descent method, which may get stuck in a local minimum, leading to failure in finding the globally optimal solution. Moreover, a multi-layer perceptron suffers from locking a systematic determination of the network structure appropriate for a given problem. It is usually the case to determine the number of hidden nodes by trial and error. In this paper, we propose a new algorithm to efficiently train a multi-layer perceptron. OUr algorithm uses stochastic perturbation in the weight space to effectively escape from local minima in multi-layer perceptron learning. Stochastic perturbation probabilistically re-initializes weights associated with hidden nodes to escape a local minimum if the probabilistically re-initializes weights associated with hidden nodes to escape a local minimum if the EGP learning gets stuck to it. Addition of new hidden nodes also can be viewed asa special case of stochastic perturbation. Using stochastic perturbation we can solve the local minima problem and the network structure design in a unified way. The results of our experiments with several benchmark test problems including theparity problem, the two-spirals problem, andthe credit-screening data show that our algorithm is very efficient.

• Asian Pacific Journal of Cancer Prevention
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• 제15권14호
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• pp.5799-5804
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• 2014

Background: Radiofrequency ablation (RFA) is the most widely used and studied method internationally for the local treatment of liver tumors. However, the extension of coagulation necrosis in one RFA procedure is limited and incomplete coverage of the damaged area can lead to a high local recurrence rate. Objective: In this study, we compared the effects of different solutions in enhancing hepatic radiofrequency by establishing a rabbit VX2 liver cancer model. We also determined the optimal solution to maximise effects on the extent of RFA-induced coagulation necrosis. Methods: Thirty VX2 tumor rabbits were randomly assigned to five groups: group A, RFA alone; group B, RFA with anhydrous ethanol injection; group C, RFA with 5% hypertonic saline injection; group D, RFA with lidocaine injection; and group E, RFA with a mixed solution. Routine ultrasound examinations and contrast-enhanced ultrasound (CEUS) of the ablation areas were performed after RFA. Then, we measured the major axis and transverse diameter and compared the areas of coagulation necrosis induced by RFA. Results: The mean ablation area range increased in groups B, C and especially E, and the scopes were greater compared with group A. Preoperative application of anhydrous ethanol, hypertonic saline, lidocaine and the mixed solution (groups B, C, D and E, respectively) resulted in larger coagulation necrosis areas than in group A (p<0.05). Among the groups, the coagulation necrosis areas in group E was largest, and the difference was statistically significant compared with other groups (p<0.05). Pathological findings were consistent with imaging results. Conclusions: A mixture of dehydrated alcohol, hypertonic saline and lidocaine injected with RFA increases the extent of coagulation necrosis in the liver with a single application, and the mixed solution is more effective than any other injection alone.

• Journal of Dental Anesthesia and Pain Medicine
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• 제23권5호
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• pp.273-280
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• 2023

Background: Intraoral local anesthesia is essential for delivering dental care; however, injection of this local anesthetic is perceived as the most painful and distressing agent for children, parents, and healthcare providers. Reducing pain as much as possible is essential to ensure smooth subsequent treatment procedures, especially in pediatric dentistry. In clinical practice, oral sucrose administration has been reported to decrease the pain during heel lance and cold pressor tests in neonates and children. This study aimed to determine whether the prior administration of a 30% sucrose solution reduced the pain related to inferior alveolar nerve block in children. Methods: A total of 42 healthy children aged 7-10 years requiring dental treatment of mandibular molars involving inferior alveolar nerve block were recruited. The participants' demographic details were recorded, height and weight were measured, and the anesthetic injection was delivered after receiving the respective intraoral sucrose solution and distilled water by the intervention (group 1) and control (group 2) group participants for 2 min. The subjective pain perceived during injection was measured using an animated emoji scale. The pain scores between the groups were compared using the Mann-Whitney U test. Results: The median pain score and range for the intervention and control groups were 4 (2 - 6) and 6 (4 - 8), respectively, and statistically significant differences (P < 0.001) were observed in the intervention group. Age, sex, height, and weight did not influence the analgesic effect of the sucrose solution. Conclusion: Oral administration of sucrose may relieve pain associated with inferior alveolar nerve block in children.