• 물과 미래
• /
• 제11권1호
• /
• pp.39-46
• /
• 1978

The approaching deep water wave heights and directions affect the wave energy which is carried to the coast. By studing the relations between the longshore wave energy theory and the evolution of coastline, writer can arrive following conclusion. The longshore lottoral drifting affects to a great deal the formation of the coast, and by investigating on the eastern coastal geomophorogy of korea, the theory was proued as a true and made it possible to an approaching to the subdivided classification of eastern coast of lorea. That is to asy that angle taken by the level between the wave crest line of prevailing wave(NE) and the coastline was measured as less than 15#, and in the area neighboring the river which served as source of Sand parrticles, there are grand scale formation of sand beach expectable, in the other hand the formation of sand beach in case of $35^{\circ}{\leq}{\alpha }o{\leq}55^{\circ}$ which represents the vivid phenomena of longshore littoral drifting was proved not influencial but rather transformed into a rocky coast. Depending on the above facts the writer classified general shape of the coast affected by the vivid wave action into the following three, (1) The equilibrium beach. (2) Erosinal beach. (3) Geomophorogical beach, and made the sandy and rocky coast are subdivided as S-A.B.C. and R-DEF.

• 제어로봇시스템학회:학술대회논문집
• /
• 제어로봇시스템학회 2003년도 ICCAS
• /
• pp.1587-1592
• /
• 2003

There are three kinds of singularity in controlling redundant manipulators. Kinematic, algorithmic and representation singularities are those. If manipulators fall into any singularity without proper action to avoid it, the control system must go away from our desire, and we can meet a dangerous situation. Hence, we have to deal the singularities very carefully. In this paper, we describe an on-line solution for avoiding the occurrence of both algorithmic and kinematic singularities in task-priority based kinematic controllers of robotic manipulators. Representation singularity can be easily avoided by using proper representation algorithm, so, in this paper, we only consider kinematic and algorithmic singularities. The proposed approach uses a desired task reconstruction and a successive task projection in order to maintain the measure for singularity over a user defined minimum value. It shows a gain in performance and a better task error especially when working in proximity of singular configurations. It is particularly suitable for autonomous systems where an off-line trajectory control scheme is often not applicable. The advantage and performance of the proposed controller is verified by simulation works. And, the experiment with real manipulator is remaining for the future works.

• 한국응용약물학회:학술대회논문집
• /
• 한국응용약물학회 1994년도 제2회 추계심포지움
• /
• pp.147-172
• /
• 1994

Aziridinylbenzoquinones such as 3, 6-diaziridinyl-1, 4-benzoquinone (DZQ) and its 2, 5-methyl analog (MeDZQ) require bioreductive activation in order to elicit their anticancer activities. To determine the involvement of DTD in the activation of these drugs, we have used a ligation-mediated polymerase chain reaction to map the intracellular alkylation sites in a sing1e copy gene at the nucleotide level. We have performed this analysis in two human colon carcinoma cells, one proficient (HT-29) and one deficient (BE) in DT-diaphorase (DTD) activity. In the DTD proficient HT-29 cell line, DZQ and MeDZQ were found to alkylate both 5'-(A/T)G(C)-3' and 5'-(A/T)A-3' sequences. This is consistent with the nucleotide preferences observed when DZQ and MeDZQ are activated by purified DTD to reactive metabolites capable of alkylating DNA in vitro [Lee, C. -S., Hartley, J. A., Berardini, M. D., Butler, J., Siegel., D., Ross, D., & Gibson, N. W. (1992) Biochemistry, 31: 3019-3025]. Surprisingly in the DTD-deficient BE cell line a pattern of alkylation induced by DZQ and MeDZQ similar to that observed in the DTD-proficient HT-29 cells was observed. This suggests that reductive enzymes other than DTD can be involved in activating DZQ and MeDZQ to DNA reactive species in vivo.

• 비파괴검사학회지
• /
• 제29권3호
• /
• pp.214-218
• /
• 2009

The occlusal force of the tooth leads to loss of tooth tissue owing to attrition and abrasion, and may cause abfraction and pathological change of the dentin. Thus, we developed finite element models, examined them by applying ordinary occlusal force, and analyzed the stress distribution. Specimens used were mandibular first premolars from 15 Korean males and 13 females and were made into finite element models from medical images that were obtained using a Micro-CT. We have found that the irregular feature of the tooth is not only useful to masticating and pronouncing as well known, but it is also suitable for protecting inner tissue by dispersing stress and delivering proper pressure to periodontal tissue to continue a physiological action. Also, image analysis could let us know the factor that is the cause of a disorder due to stress concentration in the cervical line. These results are expected to support the field of dental treatment planning, operating procedure and clinical trial, and the advance of technical expertise to develop implants and dentures.

• 생약학회지
• /
• 제52권3호
• /
• pp.143-148
• /
• 2021

This study was performed to elucidate the inhibitory effects of Alveopora japonica extract on melanin synthesis by measuring the levels of cell viability, mRNA expression, tyrosinase activity, and melanin production in the B16F10 cell line. The effects of A. japonica extract on tyrosinase-related protein 1 (TYRP1), TYRP2, tyrosinase (TYR), and microphthalmia-associated transcription factor (MITF) mRNA expression levels and melanin content were determined. Quantitative real-time RT-PCR show that A. japonica extract decrease the mRNA expression levels of TYRP1, TYRP2, TYR, and MITF in B16F10 cell line, resulting in lower levels of melanin production compared to α-MSH-treated B16F10 cells. Tyrosinase activity assays reveal that A. japonica extract decrease melanin production in B16F10 cells. These results demonstrate the whitening effects of A. japonica extract on B16F10 cells; thus, A. japonica extract is a potent ingredient for skin whitening. Further research is needed on the mechanism of action of A. japonica extract. Such research will benefit not only cosmetics, but also the health food and medical industries.

• 생약학회지
• /
• 제52권2호
• /
• pp.99-104
• /
• 2021

This study was performed to elucidated the inhibitory effects of 6,8-diprenylorobol on melanin synthesis by measuring the levels of cell viability, mRNA expression, tyrosinase activity, and melanin production in the B16F10 cell line. The effects of 6,8-diprenylorobol on tyrosinase-related protein 1 (TYRP1), TYRP2, tyrosinase (TYR), and microphthalmia-associated transcription factor (MITF) mRNA expression levels and melanin content were determined. Quantitative real-time RT-PCR shows that 6,8-diprenylorobol decreases the mRNA expression levels of TYRP1, TYRP2, TYR, and MITF in B16F10 cell line, resulting in lower levels of melanin production compared to α-MSH-treated B16F10 cells. Tyrosinase activity assays reveal that 6,8-diprenylorobol decreases melanin production in B16F10 cells. These results demonstrate the whitening effects of 6,8-diprenylorobol on B16F10 cells; thus, 6,8-diprenylorobol is a potent ingredient for skin whitening. Further research is needed on the mechanism of action of 6,8-diprenylorobol. Such research will benefit not only cosmetics, but also the health food and medical industries.

• 생약학회지
• /
• 제52권1호
• /
• pp.13-18
• /
• 2021

This study was performed to clarify the whitening effects of anthricin on the B16F10 cell line. In order to elucidate the whitening effects of anthricin on the B16F10 cell line, cell viability, messenger ribonucleic acid (mRNA) expressions, tyrosinase activity assay, and melanin production assay were measured. The effects of anthricin on tyrosinase-related protein 1(TYRP1)/TYRP2/tyrosinase (TYR)/microphthalmia-associated transcription factor (MITF) mRNA expressions and melanin content were determined. Quantitative real-time RT-PCR showed that anthricin decreased the mRNA expression level of TYRP1/TYRP2/TYR/MITF genes and melanin production contents than α-MSH-treated B16F10 cells. The tyrosinase activity assay revealed that anthricin decreased the melanin production on the B16F10 cells. These data show that anthricin increases the whitening effects on the B16F10 cells; thus, anthricin is a potent ingredient for skin whitening. Thus, further research on the mechanism of action of anthricin for the development of not only cosmetics, but also healthy food and medicine should be investigated.

• 조명전기설비학회논문지
• /
• 제25권9호
• /
• pp.75-79
• /
• 2011

The MOV(Metal Oxide Varistor), a voltage limiting element, has been installed in the SPD(Surge Protective Device) or inside the internal circuit of an electronic appliance for protection of the electric power system and electronic device against electrical surge. Such an MOV is exposed, however, to the risk of the thermal runaway resulting from excessive voltage and deterioration. In this paper, a reciprocal action has been tested and analyzed using a phosphorus bronze switching module and the low-temperature solder. And a short current break characteristic test linked with the circuit breaker has been performed to limit the inrush current when the MOV breaks down. It has been proven that the phosphorus bronze switching module installed inside the internal circuit can improve the safety of the power line system and the electronic device.

• 한국철도학회:학술대회논문집
• /
• 한국철도학회 2011년도 춘계학술대회 논문집
• /
• pp.1009-1013
• /
• 2011

Seoul Metro Line 1 to 4 guests per day to 4.5 million people have been using the subway. This is close to the city population, 57 percent of people use the subway and found that 57 percent of people use the subway and found that this is close to the city population. Motor vehicle indoor air quality, especially of the major factors affecting is passenger's clothing, cosmetics, adhesives and formaldehyde by the action and so are able to keep. Enclosure 30ppm formaldehyde during prolonged exposure at concentrations above the nose, bronchial cough and a burning can cause symptoms. It is necessary to introduce an appropriate ventilation system. 1-4 Line Press in 2008, leaving the subway, and normally the train measured in room air quality. Measurements in 2005, $19.3{\sim}83{\mu}g/m^3$, 2008 Year ND ~ $61.7{\mu}g/m^3$ is. When congestion(rush hour) to temporarily increase the formaldehyde can result in a higher number. Automatic detection of formaldehyde and improve ventilation to a practical system, and it is necessary to chatneun. In research since 2006, Removal of formaldehyde were analyzed for the study. the passengers on the effects of formaldehyde in rush hour, the plan for increasing the ventilation through the analysis of various factors, such as electric vehicle practical ways to improve air quality have been studied.

• 한국사이버테러정보전학회:학술대회논문집
• /
• 한국사이버테러정보전학회 2004년도 제1회 춘계학술발표대회
• /
• pp.275-282
• /
• 2004

디지털 저작물의 전송환경이 빠른 속도로 바뀜에 따라서 디지털 저작물의 저작권 보호가 중요한 이슈로 부각되고 있다. DRM(Digital Right Management)은 디지털 저작자나 출판업자, 그리고 인터넷 서비스 제공자들에게 디지털 저작물을 접근하고 사용하는데 있어서 신뢰할수 있는 환경을 만들수 있는 관심있는 분야이다. 본 논문에서는 라이선스 에이전트를 이용하여 기존의 DRM 기법이 가지고 있는 정적인 DRM이나 온라인환경에 제한된 어플리케이션의 단점을 개선한 디지털 저작물의 보호기법에 대하여 제안한다. 제안된 논문은 동적인 DRM기법으로 동적인 요구 제어 기술을 바탕으로 라이선스 에이전트를 이용하여 온라인과 오프라인 환경에서 동시에 모니터링과 추적을 수행한다. 제안된 시스템은 PKI 보안 환경에서 사용자의 행동이나 데이터 보안을 실시간으로 감시하여 불법적인 접근과 사용을 막는다.