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Comparison of local reaction at injection site following intramuscular administration with three commercial atrophic rhinitis vaccines in pigs

  • Kim, Myung-Hyee;Kwon, Taeyong;Yoo, Sung J.;Seo, Sang won;Park, Jun Woo;Lyoo, Young S.
    • Korean Journal of Veterinary Service
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    • v.41 no.4
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    • pp.251-255
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    • 2018
  • Bordetella bronchiseptica and Pasteurella multocida are two main pathogens responsible for atrophic rhinitis (AR), which causes considerable economic losses in swine industry worldwide. Commercial vaccine has been widely used to prevent the damage from AR in Korea. Adverse effects of vaccination at the injection site have been reported, which results in the numerous complaint from farms. However, data on about local reaction at the injection site remains limited. In this study, we compared the local adverse effects of three commercial vaccines following intramuscular injection. The results showed that no gross lesion was founded at the injection sites of all three vaccines. In histopathologic examination, a various level of lesions was identified. Especially, the local reaction of vaccine including saponin as an adjuvant showed the lowest level of histopathological lesions, when compared to those of oil-based and vitamin E-based vaccines. Therefore, this study would provide the information about the extent of local reaction at the injection site and help the farmer to select AR vaccine in order to avoid adverse reaction due to vaccination.

Examination of the Fragmentation Behavior of Hemin and Bilin Tetrapyrroles by Electrospray Ionization and Collision-induced Dissociation

  • Sekera, Emily R.;Wood, Troy D.
    • Mass Spectrometry Letters
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    • v.9 no.4
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    • pp.91-94
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    • 2018
  • Bilin tetrapyrroles are metabolic products of the breakdown of porphyrins within a species. In the case of mammals, these bilins are formed by the catabolism of heme and can be utilized as either biomarkers in disease or as an indicator of human waste contamination. Although a small subset of bilin tandem mass spectrometry reports exist, limited data is available in online databases for their fragmentation. The use of fragmentation data is important for metabolomics analyses to determine the identity of compounds detected within a sample. Therefore, in this study, the fragmentation of bilins generated by positive ion mode electrospray ionization is examined by collision-induced dissociation (CID) as a function of collision energy on an FT-ICR MS. The use of the FT-ICR MS allows for high mass accuracy measurements, and thus the formulas of resultant product ions can be ascertained. Based on our observations, fragmentation behavior for hemin, biliverdin and its dimethyl ester, phycocyanobilin, bilirubin, bilirubin conjugate, mesobilirubin, urobilin, and stercobilin are discussed in the context of the molecular structure and collision energy. This report provides insight into the identification of structures within this class of molecules for untargeted analyses.

Successful management of absent sternum in an infant using porcine acellular dermal matrix

  • Semlacher, Roy Alfred;Nuri, Muhammand A.K.
    • Archives of Plastic Surgery
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    • v.46 no.5
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    • pp.470-474
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    • 2019
  • Congenital absent sternum is a rare birth defect that requires early intervention for optimal long-term outcomes. Descriptions of the repair of absent sternum are limited to case reports, and no preferred method for management has been described. Herein, we describe the use of porcine acellular dermal matrix to reconstruct the sternum of an infant with sternal infection following attempted repair using synthetic mesh. The patient was a full-term male with trisomy 21, agenesis of corpus callosum, ventricular septal defect, patent ductus arteriosus, right-sided aortic arch, and congenital absence of sternum with no sternal bars. Following removal of the infected synthetic mesh, negative pressure wound therapy with instillation was used to manage the open wound and provide direct antibiotic therapy. When blood C-reactive protein levels declined to ${\leq}2mg/L$, the sternum was reconstructed using porcine acellular dermal matrix. At 21 months postoperative, the patient demonstrated no respiratory issues. Physical examination and computed tomography imaging identified good approximation of the clavicular heads and sternal cleft and forward curvature of the ribs. This case illustrates the benefits of negative pressure wound therapy and acellular dermal matrix for the reconstruction of absent sternum in the context of infected sternal surgical site previously repaired with synthetic mesh.

Applications of Drones for Environmental Monitoring of Pollutant-Emitting Facilities

  • Son, Seung Woo;Yu, Jae Jin;Kim, Dong Woo;Park, Hyun Su;Yoon, Jeong Ho
    • Proceedings of the National Institute of Ecology of the Republic of Korea
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    • v.2 no.4
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    • pp.298-304
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    • 2021
  • This study aimed to determine the applicability of drones and air quality sensors in environmental monitoring of air pollutant emissions by developing and testing two new methods. The first method used orthoimagery for precise monitoring of pollutant-emitting facilities. The second method used atmospheric sensors for monitoring air pollutants in emissions. Results showed that ground sample distance could be established within 5 cm during the creation of orthoimagery for monitoring emissions, which allowed for detailed examination of facilities with naked eyes. For air quality monitoring, drones were flown on a fixed course and measured the air quality in point units, thus enabling mapping of air quality through spatial analysis. Sensors that could measure various substances were used during this process. Data on particulate matter were compared with data from the National Air Pollution Measurement Network to determine its future potential to leverage. However, technical development and applications for environmental monitoring of pollution-emitting facilities are still in their early stages. They could be limited by meteorological conditions and sensitivity of the sensor technology. This research is expected to provide guidelines for environmental monitoring of pollutant-emitting facilities using drones.

A study on the Estimation of Weight of Purchasing Power Indicator for Export Market Selection of Defense Industry Products (방산물자 수출시장 선정을 위한 구매력 지표의 가중치 산정에 관한 연구)

  • Joo, E-Wha;Shim, Sang-Ryul
    • Korea Trade Review
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    • v.44 no.1
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    • pp.193-205
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    • 2019
  • It is important to accurately analyze the various factors such as the local situation of the purchasable countries and the international situation in order to export defense industrial goods developed in Korea and to enter overseas markets based on the results. In the case of defense materials, unlike the civilian sector, there are a limited number of countries with high export potential. Therefore, to select a possible export market, it is necessary to consider the purchasing power index through the examination of the purchasability of the exportable market. Therefore, the present study chose a total of 18 purchasing power indicators in five major categories of economic power, military power, defense science and technology level, friendly relations with Korea, and possibility of dispute. By calculating each weight with AHP and Fuzzy-AHP analysis, the results was presented the purchasing power index and the weighting. Based on the results will contribute to the study on the method of selecting the export market of the defense materials and the establishment of the export policy of the defense industry.

Examination on Autonomous Recovery Algorithm of Piping System (배관 체계 자율 복구 알고리즘 비교, 분석 및 고찰)

  • Yang, Dae Won;Lee, Jeung-hoon;Shin, Yun-Ho
    • Journal of the Korean Society of Safety
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    • v.36 no.4
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    • pp.1-11
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    • 2021
  • Piping systems comprising pumps and valves are essential in the power plant, oil, and defense industry. Their purpose includes a stable supply of the working fluid or ensuring the target system's safe operation. However, piping system accidents due to leakage of toxic substances, explosions, and natural disasters are prevalent In addition, with the limited maintenance personnel, it becomes difficult to detect, isolate, and reconfigure the damage of the piping system and recover the unaffected area. An autonomous recovery piping system can play a vital role under such circumstances. The autonomous recovery algorithms for the piping system can be divided into low-pressure control algorithms, hydraulic resistance control algorithms, and flow inventory control algorithms. All three methods include autonomous opening/closing logic to isolate damaged areas and recovery the unaffected area of piping systems. However, because each algorithm has its strength and weakness, appropriate application considering the overall design, vital components, and operating conditions is crucial. In this regard, preliminary research on algorithm's working principle, its design procedures, and expected damage scenarios should be accomplished. This study examines the characteristics of algorithms, the design procedure, and working logic. Advantages and disadvantages are also analyzed through simulation results for a simplified piping system.

A phenomenological study on pre-hospital care of 119 EMT (119구급대원의 현장 및 이송 중 응급처치 경험에 대한 현상학적 연구)

  • Hye-ji, Kwon;Young-jeon, Shin
    • The Korean Journal of Emergency Medical Services
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    • v.26 no.3
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    • pp.71-91
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    • 2022
  • Purpose: This study aimed to provide baseline data for implementing advanced life-support for 119EMTs. This is done with an in-depth examination of the emergency care experiences of the 119EMTs on-site and during transportation. Methods: Interviews were conducted with twelve 119EMTs, and the data were analyzed using the phenomenological method. Results: The 34 topics had 19 sub-components and were analyzed according to seven categories: 'A work environment where you cannot focus only on emergency care on-site and during transportation', '119EMTs struggling with manpower shortage', 'Current status of education blocking the upward standardization of 119EMT', 'Implementation of professional emergency care was held back due to the limited legal scope of 119EMT', 'Medical oversight makes it difficult to implement emergency care due to low flexibility', '119EMTs who cannot choose hospital selection and find it difficult to receive help', 'An evaluation system not reflecting reality at all that only leaves high scores'. Conclusion: This study was undertaken to implement specialized emergency care for 119EMTs; not only the necessity of reviewing the expansion of the work scope of 119EMTs but also the necessity of effective 'Medical Oversight system' reorganization raised as well.

Machine learning model for predicting ultimate capacity of FRP-reinforced normal strength concrete structural elements

  • Selmi, Abdellatif;Ali, Raza
    • Structural Engineering and Mechanics
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    • v.85 no.3
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    • pp.315-335
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    • 2023
  • Limited studies are available on the mathematical estimates of the compressive strength (CS) of glass fiber-embedded polymer (glass-FRP) compressive elements. The present study has endeavored to estimate the CS of glass-FRP normal strength concrete (NSTC) compression elements (glass-FRP-NSTC) employing two various methodologies; mathematical modeling and artificial neural networks (ANNs). The dataset of 288 glass-FRP-NSTC compression elements was constructed from the various testing investigations available in the literature. Diverse equations for CS of glass-FRP-NSTC compression elements suggested in the previous research studies were evaluated employing the constructed dataset to examine their correctness. A new mathematical equation for the CS of glass-FRP-NSTC compression elements was put forwarded employing the procedures of curve-fitting and general regression in MATLAB. The newly suggested ANN equation was calibrated for various hidden layers and neurons to secure the optimized estimates. The suggested equations reported a good correlation among themselves and presented precise estimates compared with the estimates of the equations available in the literature with R2= 0.769, and R2 =0.9702 for the mathematical and ANN equations, respectively. The statistical comparison of diverse factors for the estimates of the projected equations also authenticated their high correctness for apprehending the CS of glass-FRP-NSTC compression elements. A broad parametric examination employing the projected ANN equation was also performed to examine the effect of diverse factors of the glass-FRP-NSTC compression elements.

Diabetic Foot and Soft Tissue Necrosis Caused by Moxibustion Burn Injury (뜸치료에 의한 화상으로 발생한 당뇨족 및 연부조직 괴사)

  • Han, Song Hyun;Jo, Dong In;Kim, Cheol Keun;Kim, Soon Heum
    • Journal of the Korean Burn Society
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    • v.23 no.2
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    • pp.60-63
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    • 2020
  • A 72-year-old man with diabetes, who underwent moxibustion, developed a foot wound but did not receive proper treatment. Examination showed a soft tissue defect (6×6 cm) on the dorsal aspect of the right foot with involvement of the first and second toes along with some phalangeal bone loss. The wound was treated with a skin graft and healed without complications. The right calf showed a raw surface (4×3 cm), which underwent epithelialization after conservative treatment. We observed four focal necrotic lesions (1.5×1.5 cm) on the right lower leg and anterior chest, which served as indicators of moxibustion, and debridement and primary closure were performed. Moxibustion is increasingly used as a therapeutic option; however, statistical data describing its adverse effects are limited. Moxibustion significantly increases skin temperature and can cause burn injuries. It is important to prevent moxibustion-induced adverse effects and avoid severe complications, particularly in patients with diabetes.

A Study On the Development of the Pi-Yin Theory (비음(脾陰) 이론의 형성에 대한 고찰)

  • Yun, Ki-ryoung
    • Journal of Korean Medical classics
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    • v.35 no.3
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    • pp.91-106
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    • 2022
  • Objectives : To examine the developmental process of the Pi-Yin theory since the Huangdineijing to Miu Xiyong. Methods : Related contents since the Huangdineijing to Miu Xiyong was searched to examine the development of the Pi-Yin theory. Results & Conclusions : In the Huangdineijing and Shanghanzabinglun, the origin of the Pi's body fluids that nurtures everywhere is explained to be the Wei, which limited the development of the Pi-Yin theory. Liu Wansu understood tonification of the Pi by means of moistening medicinals to mean adding Pi-Yin based on the manifestation of dryness in the case of dampness deficiency which is the main Qi of the Pi and Wei. Zhu Danxi understood adding Pi-Yin as accomplished by supplementing Blood. The understanding of the nature of Pi to be 'likes dryness and hates dampness' leading to thinking that drying dampness tonifies the Pi was the reason why the Pi-Yin theory could not develop fully. Miu Xiyong accepted theories of both Li Dongyuan and Zhu Danxi, and constructed the Pi-Yin theory to bring caution to the unwanted effects of using Baizhu wrongly. Through examination of the developmental process of the Pi-Yin theory, it could be understood that rather than focusing on the physiological function of the Pi-Yin and ways of maintaining its proper functioning, the theory was developed to bring caution to using medicinals with dry and hot properties that could dry the Pi-Yin.