• Title/Summary/Keyword: Life-long effects

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Effects of Audio-visual Entertainment and Soft Tissue Mobilization on Pressure Pain Thresholds, Psychophysiological parameters, and Brain waves in University Students with Tension-type Headache (긴장성 두통이 있는 대학생들에게 시청각적 엔터테인먼트와 연부조직 가동술이 압력통각역치, 바이오피드백, 뇌파에 미치는 영향)

  • Jung, Dae-In;Lee, Eun-Sang;Kim, Hyun-Joong
    • Journal of Korea Entertainment Industry Association
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    • v.14 no.7
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    • pp.539-548
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    • 2020
  • TTH(tension-type headache) is the most common primary headache among adults. Long-term headaches cause chronic headaches and have a better impact on daily life. The purpose of this study is to compare the contributions to TTH through AVE(audio-visual entertainment) and STM(soft tissue mobilization) suitable for management of pathogenic and psychogenic factors of TTH. The participants of this study were from 30 people who complained of intermittent or persistent headaches for more than 6 months, and 10 participants each in the AVE group, STM group, and AVE plus STM group. In the assigned group, a total of 12 sessions were performed three times a week for 4 weeks after the baseline, followed by post-test. Outcome measures measured PPTs(pressure pain thresholds), psychophysiological parameters, and EEG(electroencephalogram). The measured results were analyzed for interaction between time and group through a two way rmANOVA(repeated measurement variance analysis). As a result of the PPTs, interaction was found in the results of the right trapezius (p<.05), and the more improvement was observed in the AVE group. Therefore, through AVE based on psychological factors rather than direct access to the muscles of pathogenic factors, a positive impact on the PPTs was shown, but the average value of the psychophysiological parameters and brain waves that were not statistically significant. The amount of change was observed. Through this, it is suggested that audio-visual stimulation could be considered in the management of TTH.

Chemical Prelithiation Toward Lithium-ion Batteries with Higher Energy Density (리튬이온전지 고에너지밀도 구현을 위한 화학적 사전리튬화 기술)

  • Hong, Jihyun
    • Journal of the Korean Electrochemical Society
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    • v.24 no.4
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    • pp.77-92
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    • 2021
  • The energy density of lithium-ion batteries (LIBs) determines the mileage of electric vehicles. For increasing the energy density of LIBs, it is necessary to develop high-capacity active materials that can store more lithium ions within constrained weight. The rapid progress made in cathode technology has realized the utilization of the near-theoretical capacity of cathode materials. In contrast, commercial LIBs have still exploited graphite as active material in anodes since the 1990s. The most promising way to increase anodes' capacity is to mix high-capacity and long-cycle-life silicon oxides (SiOx) with graphite. However, the low initial Coulombic efficiency (ICE) of SiOx limits its content below 15 wt%, impeding the capacity increase in anodes. To address this issue, various prelithiation techniques have been proposed, which can improve the ICE of high-capacity anode materials. In this review paper, we introduce the principles and expected effects of prelithiation techniques reported so far. According to the reaction mechanisms, the strategies are categorized. Mainly, we focus on the recent progress of solution-based chemical prelithiation methods with commercial viability, of which lithiation reaction occurs homogeneously at liquid-solid interfaces. We believe that developing a cost-effective and mass-scalable prelithiation process holds the key to dominating the anode market for next-generation LIBs.

The effectiveness and safety of acupuncture combination treatment on smoking cessation: A protocol for systematic review (금연에 대한 침술 병용 치료의 효과 및 안전성 : 체계적 검토를 위한 프로토콜)

  • In Suh Choi;Won-Suk Sung;Min-gi Jo;Jung-Hyun Kim;Yeon-Cheol Park;Eun-Jung Kim;Yong-Hyeon Baek;Geun-Woo Kim;Byung-Kwan Seo
    • Journal of Convergence Korean Medicine
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    • v.3 no.1
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    • pp.5-13
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    • 2022
  • Objectives: Smoking had a long negative impact on public health. The ingredients of a cigarette are major risk factors for several diseases. Owing to the problems about economic and quality of life, we need to ensure smoking cessation (SC). There are several approaches for SC including pharmacological therapy, nicotine replacement therapy, education, and behavioral intervention. However, due to some limitations, other alternative approaches are gaining popularity. Acupuncture has been reported to have few side effects and be more effective than some conventional treatments in several articles. However, there are no systematic reviews on the comparison of acupuncture combination treatment with other conventional monotherapies. Methods: Randomized controlled trials that used acupuncture as an adjunct treatment for SC will be searched and data will be summarized according to the predefined criteria. The primary outcome will be the abstinence rate, and secondary outcomes will be adverse events and biochemical indicators. We will use Review Manager to perform a meta-analysis, Cochrane Collaboration Risk of Bias tool for the risk of bias assessment, and the Grades of Recommendation, Assessment, Development and Evaluation approach to determine the quality of evidence. We will investigate the efficacy and safety of acupuncture combination treatment for SC with this study. Ethics and dissemination: This study will provide reliable clinical evidence on additional effect of acupuncture on smoking cessation. We will publish our results in a peer-review journal.

Voice therapy for pitch problems following thyroidectomy without laryngeal nerve injury (신경학적 손상이 없는 갑상선 술 후 음도문제의 음성치료)

  • Ji-sung Kim;Mi-jin Kim
    • Phonetics and Speech Sciences
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    • v.15 no.3
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    • pp.53-58
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    • 2023
  • After thyroidectomy, some patients who show normal vocal cord movement still complain of subjective voice problems, which could lead to a decrease in quality of life related to communication. This study aims to investigate the effectiveness of a newly designed voice therapy applying neck exercise and semi-occluded vocal tract exercise (SOVTE) to improve voice problems after thyroidectomy without neurological injury. For this purpose, voice therapy was randomly assigned to 10 women who received thyroidectomy. Acoustic analysis [fundamental frequency, jitter, shimmer, noise-to-harmonics ratio, min Voice Range Profile (VRP), max VRP, VRP] was performed before and after surgery and immediately after voice therapy to compare voice changes. The study showed a statistically significant increase in max VRP and VRP after voice therapy compared to before surgery. These results suggest that the voice therapy methods in this study effectively improve a major symptom of voice problems after thyroidectomy, specifically the reduction in the high-frequency range. However, this study was limited in the number of s participants and did not control for the type of surgery. Therefore, further research utilizing larger sample sizes and controlled variables is needed to investigate the long-term effects of voice therapy.

A Study on awareness of environmental management Knowledge and enviromental management behavior of Housewives (주부의 환경관리지식 인지도와 환경관리행동에 관한 연구)

  • 노남숙
    • Hwankyungkyoyuk
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    • v.7 no.1
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    • pp.106-122
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    • 1994
  • The purpose of this study to investigate the awareness of environmental management knowledge and behavior and the effect of independent variables (The environmental management behavior of housewives are composed of five activities-clothing, eating, housing, buying, family management. The independent variables are composed of objective variable and subjective variable). The Research Questions are as follows; 1. Are there significant differences in the housewife's awareness of the environmental management knowledge according to the objective variable and the subjective variable? 2. How much are the effects of related variables on the awareness of environmental management knowledge? 3. Are there significant differences in the housewife's environmental management behavior according to objective variable and subjective variable and awareness of environmental management knowledge? 4. How much are effects of related variables on the housewife's environmental management behavior? For these purpose, a theoretical framework was developed by literature review and applied to empirical test. The data was collected through the questionnaire those respondents were 477 housewives in seoul. It was analyzed by various statistical methods such as Frequency. Percentile, GLM, F-test, T-test, Duncan's Multiple Range Test, Pearson's Correlations Analysis Simple Regression Analysis, and Multiple Regression Analysis. The results of this research are as follows; 1. The awareness of environmental management knowledge had significant differences according to the variables such as housewife's age, husband's job, family number, education experience of environment, frequencies of contracting mass media, the perceived adequacy of resources, social-altruistic orientation. 2. Among all of these variables affecting the awareness of environmental management knowledge, the perceived adequacy of resources had the highest effects and the next were family number, social-altruistic, type of residence in order. 3. Total Environmental management behavior of housewives had significant differences according to the variables such of environment, frequencies of contracting mass media, the satisfaction of household labor, the perceived adequacy of resources, biospheric orientation, social-altruistic orientation, egoism orientation, the awareness of environmental management knowledge. The clothing, eating, housing, family management behavior had the high level, the buying management behavior had the average level. The clothing, eating, housing, buying, family management behavior had significant differences according to the variables such as the satisfaction of household labor, the perceived adequacy of resources, biospheric orientation, social-altruistic orientation, egoism orientation, the awareness of environmental management knowledge. In particular, the clothing, eating, housing, buying management behavior had significant differences according to the variables such as education experience of environment. And the housing, buying management behavior had significant differences according to the variables such as frequencies of contracting mass media. 4. Among all of theses variables affecting environmental management behavior, the most influence variables was awareness of environmental management knowledge and the next were influence of housewife's job, biospheric orientation, the satisfaction of household labor, education experience of environment, frequencies of contraction mass media, egoism orientation in order. Among all of theses variables effecting the clothing, eating, housing, buying management behavior the variables affecting the family management behavior, the most influences variables was housewife's job. In the result of analysing the housewife's environmental management behavior and awareness of environmental management knowledge, influences of education experience of environment had the highest effect and frequencies of contracting mass media may more influencial than other variables. And Concrete and systematic knowledge and technique of environmental education is requisite. The result of this study could be attributed to develop the efficient environmental information. More emphasis should be given to environmental education and a long range environmental policy. in particular, environmental education be effectively related to environmental behavior, life-education and systematic support must be provided. In addition, further study of environmental problem is needed for and application of various theoretical approaches and research method.

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Compilation of 104 Experimental Theses on the Antitumor and Immuno-activating therapies of Oriental Medicine (한의학의 항종양 면역치료에 관한 연구 -1990년 이후 발표된 실험논문을 중심으로-)

  • Kang Yeon Yee;Kim Tai Im;Park Jong Ho;Kim Sung Hoon;Park Jong Dai;Kim Dong Hee
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.17 no.1
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    • pp.1-24
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    • 2003
  • This study was done to compile 104 experimental theses which are related to the antitumor and immuno-activating therapies between February 1990 through February 2002. Master's and doctoral theses were dassified by schools, degrees, materials, effects, experimental methods of antitumor and immunoactivity, and results. The following results were obtained from this study : 1. Classifying the theses by the school, 34.6% were presented by Daejeon University, 29.8% by Kyung-hee University and 11.5% by Won-kwang University. Of all theses, 51.0% were aimed for the doctoral degree and 43.3% were for the master's degree. All of three universities have their own cancer centers. 2. Classifying the theses by herb materials, complex prescription accounted for 60.3%, single herb accounted for 24.8% and herbal acupuncture accounted for 14.2%. Considering the key principles of the traditional medicine, complex prescription was much more thoroughly studied than single herb prescription. The results showed that the complex prescription had both antitumor activity and immuno-activating activity, which might reflects on multi-activation mechanisms by complex components. 3. Classifying the theses by the efficacy of herbs examined, in single herb, invigorating spleen and supplementing was 35.5%, expelling toxin and cooling was 29.0%, activating blood flow and removing blood stasis was 12.9%. In herbal acupuncture, invigorating spleen and supplementing was 52.9%, expelling toxin and cooling was 29.4%. In complex prescription, pathogen-free status was 41.9%, strengthening healthy qi to eliminate pathogen was 35.5%, strengthening healthy qi was 22.6%. It is presumed that the antitumor and immunoactivating therapy based on syndrome differentiation is the best way to develop oriental oncology. 4. Classifying the theses by antitumor experiments, cytotoxic effect was 48.1 %, survival time was 48.1 % and change of tumor size was 42.3%. Survival rate was not necessarily correlated with cytotoxicity. These data reflect the characteristic, wholistic nature of the oriental medicine which is based on BRM (biological response modifier). 5. Classifying the theses by immunoactivating experiments, hemolysin titer was 51.0%, hemagglutinin titer was 46.2% and NK cell's activity was 44.2%. In the future studies, an effort to elucidate specific molecular and cellular mechanisms of cytokine production in the body would be crucial. 6. Classifying the theses according to the data in terms of antitumor activity, 50% was evaluated good, 24.0% was excellent, and 15.5% have no effect. In an evaluation of immuno-activating activity, 35.9% was excellent and 18.0% showed a little effect. The index point, as described here, may helps to use experimental data for clinical trials. Changes in index points by varying dosage implicate the importance of oriental medical theory for prescription. 7. In 167 materials, IIP (immunoactivating index point, mean : 3.12±0.07) was significantly higher than AIP(antitumor index point, mean : 2.83±0.07). These data demonstrate that the effect of herb medicine on tumor activity depends more on immunoactivating activity than antitumor activity. This further implies that the development of herbal antitumor drugs must be preceded by the mechanistic understanding of immunoactivating effect. 8. After medline-searching tumor and herb-related articles from NCBI web site, we conclude that most of the studies are primarily focused on biomolecular mechanisms and/or pathways. Henceforth, we need to define the biomolecular mechanisms and/or pathways affected by herbs or complicated prescriptions. 9. Therefore, the most important point of oriental medical oncology is to conned between experimental results and clinical trials. For the public application of herbal therapy to cancer, it is critical to present the data to mass media. 10. To develop the relationship of experimental results and clinical trials, university's cancer clinic must have a long-range plan related to the university laboratories and, at the same time, a regular consortium for this relationship is imperative. 11. After all these efforts, a new type herbal medicine for cancer therapy which is to take care of the long-term administering and safety problem must be developed. Then, it would be expected that anti-tumor herbal acupuncture can improve clinical symptoms and quality of life (QOL) for cancer patients. 12. Finally, oriental medical cancer center must be constructed in NCC (National Cancer Center) or government agency for the development of oriental medical oncology which has international competitive power.

Effect of 1-methylcyclopropene Treatment on Extension of Freshness and Storage Potential of Fresh Ginseng (1-methylcyclopropene 처리의 수삼의 신선도 유지 및 저장성 연장 효과)

  • Park, Me-Hea;Shin, Yu-Su;Kim, Sun-Ju;Kim, Ji-Gang
    • Horticultural Science & Technology
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    • v.31 no.3
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    • pp.308-316
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    • 2013
  • Fresh ginseng has a limited storage life due to the quality change caused by microbial spoilage as well as physiological deterioration. The present study investigated the effects of 1-methylcyclopropene (1-MCP) treatment, an inhibitor of ethylene action, on the microbial growth and quality maintenance of fresh ginseng during storage. Harvested fresh ginsengs were treated with $1{\mu}L{\cdot}L^{-1}$ 1-MCP for 20 hours at $4^{\circ}C$ and then stored at room temperature (RT) for 18 days or low temperature ($4^{\circ}C$) for 160 days. After 18 days of storage at RT, the percentage weight loss in 1-MCP treated fresh ginseng (8.3%) is lower than that of control (10.1%). During long-term storage at $4^{\circ}C$, weight losses were increased slightly until 120 days without difference between non-treated and 1-MCP ginsengs. In contrast, after 120 days of storage at $4^{\circ}C$, higher increase in weight loss was observed in non-treated ginsengs than in 1-MCP treated ginsengs. Respiration rate and ethylene production of fresh ginseng were reduced by 1-MCP treatments at RT. The 1-MCP treatment also resulted in lower microbial population compared to those of non-treated ginsengs at RT. However, in ginsengs stored at $4^{\circ}C$ for short-term (45 days), no differences were noted in weight loss and microbial population between 1-MCP treated and non-treated ginsengs. Major ginsenosides was not changed by 1-MCP treatment during the 7 days of storage at RT. Results suggest that 1-MCP treatment can be used to maintain the freshness of ginseng at room temperature for short term storage and at low temperature for long term storage. 1-MCP treatment could be applied on fresh ginseng to avoid deleterious effect of exogenous ethylene during storage and shipping.

The Short-and Long-term Employment Effects of reduced Working Hours in a Putty-Clay-Model (법정근로시간 단축의 단기 및 중·장기적 고용효과 : Putty-Clay-Approach)

  • Lee, Sang-Mok
    • Journal of Labour Economics
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    • v.24 no.3
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    • pp.13-38
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    • 2001
  • The question about whether a shorter workweek may increase employment has been a serious issue and been furiously debated among collective bargainers. The advocators recommend publicly that a reduction in standard working hours will provide benefits to the unemployed through the provision of new jobs, and also can improve the quality of life workers. The opponents argue that a shorter workweek will increase labor costs and induce firms to reduce their production levels, and consequently cut back their demand for labor. Although the debate is still continuing, considerable has been made toward achieving the goal workweek reduction. The analytical framework of this paper is a Putty-clay-model, in which the short-and long-term impacts of changes in working time on the employment associated with the interrelations of wages, prices, hourly labour productivity, the firm's labor demand, business cycle and economic growth etc. must be analyzed.

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Effects of Gibberellin Treatment on the Dormancy-breaking and Germination Promotion of Carpinus laxiflora Seeds Stored for 16 Years (지베렐린 처리에 따른 서어나무 16년 저장 종자의 휴면타파 및 발아촉진 효과)

  • Han, Sim-Hee;Ku, Ja Jung;Kim, Du Hyun;Lim, Hyo-In
    • Journal of Korean Society of Forest Science
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    • v.108 no.4
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    • pp.531-539
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    • 2019
  • This study assessed the vitality of Carpinus laxiflora seeds stored for more than 15 years in order to discover optimal pre-treatment conditions for removingthe causes of seed dormancy and improving revitalization rate. Seeds were collected in October 2000 and stored at -18℃ for 16 years. Experiments to assess the revitalization ability of the seeds were performed under the following conditions: a controlled environment; in warm stratification (30 days at 23℃); in cold stratification (30 days at 4℃ andfor 30, 45, 60, and 120 days); gibberellin (GA3) treatment (24 hours per day in GA3 solutions of 100, 500, 1000, 2000, and 3000 mg·L-1); and both cold stratification and GA3 treatment (30 days at 4℃, then in a GA3 solution of 100, 500, and 1000 mg·L-1 for 2 hours). The average germination percentage(GP) of untreated seeds was 2%, and the average GP of warm-stratification seeds was 10%. Cold-stratification seeds had the highest GP at 81% for the 45-day process, while the 120-day cold-stratification seeds had the lowest GP at 67.3%. The average GP of seeds treated with GA3 ranged from 77% (100 mg·L-1) to 99% (1000 mg·L-1), indicatingsignificant differences between the treatment concentrations. The treatment effect of GA3 was highest at 500 mg·L-1 and 1000 mg·L-1, and lowest at 100 mg·L-1. The average GP of seeds treated with GA3 following cold stratification was 68%, which was lower than the cold stratification-only (73.2%) and GA3-only (88.4%) treatments. A comprehensive comparison of the seed germination characteristics according to the four treatments determined that a GA3 500 mg·L-1 pre-treatment, with the highest average GP, was ideally suited to the revitalization of long-term stored C. laxiflora seeds. Consequently, C. laxiflora stored at -18℃ for 16 years indicated strong vitality and could be regenerated by proper pre-treatment.