• Journal of Navigation and Port Research
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• v.33 no.10
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• pp.685-690
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• 2009

International Maritime Organization (IMO) recommends the installation of an Automatic Identification System (AIS) according to requirements by SOLAS to avoid maritime collision. AIS provides traffic information of other ships that may be used for maritime traffic control, SAR (Search and Rescue) and collision avoidance to apply safety management. In this paper, preliminary results to implement an aeronautical surveillance transceiver using AIS transceiver based on ADS-B concepts are described. Although altitude information is not required for AIS since the AIS is operated at MSL (Mean Sea Level), altitude information can be extracted by a GPS (Global Positioning System) chip-set in the AIS transceiver. ADS-B transceiver is implemented by defining a surveillance message format including the altitude information and modifying SOTDMA (Self-Organizing Time Division Multiple Access) protocol. Ground tests and flight tests are performed to validate the implementation results.

• The Journal of Korean Institute of Communications and Information Sciences
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• v.34 no.4C
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• pp.476-483
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• 2009

Tracking and detecting targets by the microwave seeker is affected by the clutter reflecting from the earth's surface. In order to detect retreating targets in look-down scenario, which appear in the sidelobe clutter (SLC) region, in the microwave seeker of high pulse repetition frequency (HPRF) mode, it is necessary to understand statistical characteristics of the surface SLC. Statistical analysis of SLC has been conducted for several kinds of the surface using data obtained by the captive flight test of the microwave seeker in the HPRF mode. The probability density function (PDF) fitting is conducted for several kinds and conditions of the surface. PDFs and PDF parameters, which best describe statistical distribution of the SLC power, are estimated. By using the estimated PDFs and PDF parameters, analyses for setting the target-detection thresholds, which give a desired level of target-detection false alarm probability, are made. These analysis materials for statistical characteristics of SLC power and the target-detection threshold can be used in various fields, such as development of a target-detection method, the constant false alarm rate processing.

• Journal of Microbiology and Biotechnology
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• v.26 no.12
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• pp.2206-2213
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• 2016

Recently, several studies have revealed that commercial microbial identification systems do not accurately identify the uncommon causative species of candidiasis, including Candida famata, Meyerozyma guilliermondii, and C. auris. We investigated the accuracy of species-level identification in a collection of clinical isolates previously identified as C. famata (N = 38), C. lusitaniae (N = 1 2), and M. guilliermondii (N = 5) by the Vitek 2 system. All 55 isolates were re-analyzed by the Phoenix system (Becton Dickinson Diagnostics), two matrix-assisted laser desorption ionization-time of flight mass spectrometry analyzers (a Vitek MS and a Bruker Biotyper), and by sequencing of internal transcribed spacer (ITS) regions or 26S rRNA gene D1/D2 domains. Among 38 isolates previously identified as C. famata by the Vitek 2 system, the majority (27/38 isolates, 71.1%) were identified as C. tropicalis (20 isolates) or C. albicans (7 isolates) by ITS sequencing, and none was identified as C. famata. Among 20 isolates that were identified as C. tropicalis, 17 (85%) were isolated from urine. The two isolates that were identified as C. auris by ITS sequencing originated from ear discharge. The Phoenix system did not accurately identify C. lusitaniae, C. krusei, or C. auris. The correct identification rate for 55 isolates was 92.7% (51/55 isolates) for the Vitek MS and 94.6% (52/55 isolates) for the Bruker Biotyper, as compared with results from ITS sequencing. These results suggest that C. famata is very rare in Korea, and that the possibility of misidentification should be noted when an uncommon Candida species is identified.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.30 no.7
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• pp.144-149
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• 2002

This paper presents a technique for real time multiprocessor parallel processing to develop an avionic system computer(ASC) which integrates the avionics control, navigation and fire control, cursive and raster graphic symbol generation into one line replaceable unit. The proposed method has optimal performance by adopting a logically asymmetric structure between four 32bit RISC processors based on the master-slave multiprocessing, a tightly coupled interaction level with the time shared common bus and global memory, and an efficient bus arbitration algorithm. The ASC has been verified through a series of flight tests. The relevant tests also have been rigorously conducted on the prototype ASC such as electrical test, environmental test, and electromagnetic interference test.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.34 no.3
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• pp.81-86
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• 2006

This paper deals with a driving current fault monitor design methodology for a DDV actuation system which has a dual hydraulic power supply system, and triplex electric control capability. A fault existing among these redundant channels should be detected accurately and removed timely, and the remaining channels are to be reconfigured in order to compensate the role of a removed faulty channel. An integrated analysis on the aerodynamics, flight control laws, and DDV actuation system is essential for the design of an actuation system fault monitor. A method to define a fault transient boundary which specifies a maximum travel of an actuation system caused by the first faulty operation is proposed based on the top level requirement on the fault effect specified in MIL-F-8785C.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.32 no.9
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• pp.103-113
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• 2004

The satellite is exposed to the severe vibration environments such as random vibration environments such as random vibration, acceleration, shock, and acoustics during launch ascent and transportation. It is also faced with various space environments such as thermal vacuum, radiation and microgravity during the mission life. The satellite should be designed, manufactured, assembled and tested to be able to endure in these harsh environments. This paper addresses the results of the structural and thermal design and analyses for the HAUSAT-1 picosatellite which is scheduled to launch in the first quarter of 2005 by Russian launch vehicle "Dnepr". The qualification vibration and thermal vacuum tests have been conducted and passed at the satellite level to ensure that the HAUSAT-1 mechanical system was designed to be stable with enough margin.

• Journal of the Korean Society for Aeronautical & Space Sciences
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• v.43 no.9
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• pp.814-821
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• 2015

The STEP Cube Lab. classified as a pico-class satellite has been successfully developed as a flight model(FM) to be launched in 2015. Its mission objective is to perform the on-orbit verification of fundamental space core-technologies. In this study, a thermal design concept based on the passive method to achieve the mission objective is introduced. The effectiveness of the thermal design and performance of the satellite has been verified through the acceptance level thermal vacuum test. In addition, to improve the reliability of thermal mathematical model, correlation was performed using the results of thermal balance test. This paper describes a series of process for the thermal vacuum test on the STEP Cube Lab. FM.

• Mass Spectrometry Letters
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• v.11 no.2
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• pp.36-40
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• 2020

Untargeted metabolomics is a useful tool for drug development focusing on novel chemotherapeutic and chemopreventative agents against cancer cells. In recent years, quadrupole time of flight liquid chromatography-mass spectrometry (Q-TOF LC/MS)-based untargeted metabolomic approaches have gained importance to evaluate the effect of these agents at the molecular level. The researchers working on cell culture studies still do not apply standardized methodologies on sample preparation for untargeted metabolomics approaches. In this study, the rough and wet lysis techniques performed on MCF-7 breast cancer cells were compared with each other via the Q-TOF LC/MS-based metabolomic approach. The C18 and hydrophilic interaction liquid chromatography (HILIC) columns were used for the separation of the metabolites in MCF-7 cell lysates. 505 peaks were detected through the HILIC column and 551 peaks were found through the C18 column for the wet lysis technique. This situation supported by the base peak chromatograms showed that the wet lysis technique allowed us to extract higher number of non-polar metabolites. Almost equal number of metabolites was found for the C18 and HILIC columns (697 peaks for the HILIC column and 695 peaks for the C18 column) when the rough lysis technique was used. However, the intensities of polar metabolites were higher for the rough lysis technique on base peak chromatograms for both the HILIC and C18 columns. Although cell lysis technique, which is the first step in the sample preparation for cell culture studies, does not cause dramatic differences in the number of the detected metabolite peaks, it affects the polar and non-polar metabolite ratio significantly. Therefore, it must be considered carefully especially for in vitro drug development studies.

• Korean Chemical Engineering Research
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• v.58 no.1
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• pp.106-112
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• 2020

Analyzing vitamin D levels is important for monitoring health conditions because vitamin D deficiency is associated with various diseases such as rickets, osteomalacia, cardiovascular disorders and some cancers. However, vitamin D concentration in the blood is very low with optimal level of 75 nmol/L, making quantitative analysis difficult. The objective of this study was to develop a highly sensitive analysis method for vitamin D using matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-MS). 25-hydroxyvitamin D (25(OH)D), which has been used as an indicator of vitamin D metabolites in human biofluids was chemically derivatized using a secosteroid signal enhancing tag (SecoSET) with powerful dienophile and permanent positive charge. The SecoSET-derivatized 25(OH)D provided good linearity (R² > 0.99) and sensitivity (limit of quantitation: 11.3 fmol). Chemical derivatization of deuterated 25-hydroxyvitamin D₃ (d₆-25(OH)D3) with SecoSET enabled absolute quantitative analysis using MALDI-MS. The highly sensitive method could be successfully applied into monitoring of quantitative changes of bioactive vitamin D metabolites after treatment with ketoconazole to inhibit 1α-hydroxylase reaction related to vitamin D metabolism in human breast cancer cells. Taken together, we developed a MALDI-MS-based platform that could quantitatively analyze vitamin D metabolites from cell products, blood and other biofluids. This platform may be applied to monitor various diseases associated with vitamin D deficiency such as rickets, osteomalacia and breast cancer.

• Journal of Korean Society of Industrial and Systems Engineering
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• v.40 no.2
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• pp.60-67
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• 2017

A baggage handling system (BHS) in airport is an unified system for moving the passengers' baggage in designated time. Input baggage from the check-in counter travels to the baggage claim area or cargo handling terminal through this system. In particular, entryway BHS consists of conveyors, X-ray and sorters such as tilt-tray to send the baggage to departing airplane and it could have various problems for handling certain amount of baggage in restricted time such as baggage jamming at certain merge point. This causes systemic error such as delay of the time, omissions of the baggage and even breakdown of the equipment and inefficiency. Also the increasing maximum time of the baggage passing through the BHS could delay the flight schedule and finally decrease the service level. Thus, the algorithm for controlling the flow of the merge is essential to the system. The window reservation algorithm is the one of the most frequently used methods to control the merge configuration. Above all, the reserve location, so called reserve ahead point, that allocates the window is important for the performance of the algorithm. We propose the modified window reservation algorithm and the best reserve locations by changing the reserve ahead point in the induction conveyors. The effect of various reserve ahead points such as the capacity and utility of the system were analyzed and the most effective reserve ahead point combination was found. The total baggage processing time and the utilization of the tilt-tray are properly considered when choosing the optimal Reserve ahead point combination. In the layout of this study, the configuration of four conveyors merged into one tilt-tray is studied and simulation analysis is done by AutoMod(R), 3D simulation software. Through the simulation, the window reservation algorithm is effectively operated with the best combination of reserve ahead point which reduces the maximum baggage travel time.