• 제목/요약/키워드: Lee Mi-Ja

검색결과 1,012건 처리시간 0.035초

항암화학요법 환자의 정보요구 분석 (Informational Needs of Cancer Patients Receiving Chemotherapy)

  • 한경자;이은옥;김매자;하양숙;박영숙;송미순;정재원;박성희;문미혜
    • 종양간호연구
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    • 제4권2호
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    • pp.135-142
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    • 2004
  • Purpose: To examine informational needs of cancer patients receiving chemotherapy. Methods: A cross-sectional survey design was utilized. The sample was 198 cancer patients receiving chemotherapy for a diagnosis of stomach or lung cancer at a university hospital. A modified version of Toronto Informational Needs Questionnaire was applied. Results: Subjects reported highest informational needs in prognosis dimension, followed by the treatment dimension including side effects and alternative therapy. Information about medical tests and follow-up care after the treatment was also in great need. Dimensions of support for patients/family and sexuality were low in need. The degree of informational needs was negatively correlated with patient's age and number of children. Differences were found in informational needs according to the educational level employment status, and gender of the patients, while diagnosis and treatment options did not make differences in informational needs. Conclusion: Health care professionals need to perceive informational needs of cancer patients receiving chemotherapy, and to provide them with information especially in the area of prognosis and treatment. Informational intervention would be effective when it is given with consideration of patient's characteristics.

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Supramolecular assembly of peptide molecules for applications in biological multivalent interactions

  • Lim, Yong-Beom;Park, So-Mi;Lee, Eun-Ji;Jeong, Hae-Mi;Ryu, Ja-Hyoung;Yang, Won-Young;Lee, Myong-Soo
    • 한국고분자학회:학술대회논문집
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    • 한국고분자학회 2006년도 IUPAC International Symposium on Advanced Polymers for Emerging Technologies
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    • pp.265-265
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    • 2006
  • Multivalent interactions, which are characterized by the simultaneous binding of multiple ligands on multiple receptors, are prevalent in biological system. We have shown that it is able to make a supramolecular aggregate coated with multiple functional molecules fairly easily by simply mixing one building block. In this particular example, a mannose-coated object was able to agglutinate bacterial cells with cognate binding partners through multivalent interactions. This kind of strategy can be applied in developing materials that can selectively remove pathogens. Supramolecular assembly of this type should be very useful in exploring multivalent biological interactions.

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Determination of epidemiological tetracycline MIC cut-off value for Vibrio ichthyoenteri

  • Han, Hyun-Ja;Kim, Do-Hyung;Lee, Deok-Chan;Won, Kyoung-Mi;Lee, Soon-Jeong;Cho, Mi-Young;Jee, Bo-Young;Kim, Jin-Woo
    • 한국어병학회지
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    • 제24권2호
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    • pp.95-102
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    • 2011
  • Normalized resistance interpretation (NRI) analysis for tetracycline was applied to generate information on the epidemiological cut-off value for Vibrio ichthyoenteri isolated from diseased olive flounder (Paralichthys olivaceus) larvae. Thus, 42 strains of V. ichthyoenteri were used to determine minimum inhibitory concentration (MIC) values of tetracycline using Etest. Also, 11 tetracycline resistance related genes were investigated by PCR method. Most tetracycline-resistant strains harbored both tetB and tetM with a few exceptions. NRI-derived mean and 2 SD above the mean of theoretical normal distributions of susceptible isolates were 0.33 mg/L and 1.66 mg/L, respectively. The epidemiological cut-off value for V. ichthyoenteri from the calculations could be set to S ${\leq}$ 2 mg/L. Of the 42 strains, 15 were classified as non-wild type (NWT), and MIC values of the NWT strains vary regardless of tetB and tetM detection, suggesting that there may be other mechanisms involved in tetracycline resistance in this Vibrio species.

승갈탕(升葛湯)을 사용한 아토피 피부염 환자에 대한 임상시험 (A Clinical Research about the Effects of Seunggaltang on Patients with Atopic Dermatitis)

  • 신상호;김자혜;김미보;윤화정;유선애;이승연;이미연;김규곤;고우신
    • 한방안이비인후피부과학회지
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    • 제20권2호통권33호
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    • pp.199-212
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    • 2007
  • Objective : The purpose of this clinical research was to investigate the effects of Seunggaltang on patients with atopic dermatitis. Methods : Thirteen patients were treated with Seunggaltang and ten patients were treated with placebo for 8 weeks. We observed skin humidity, skin sebum,, transepidermal water loss, skin melanin, skin erythema, total IgE class and number of allergen. And Clinic Index of Atopic Dermatitis(Extent, Intensity, Subjective symptoms, Total score) was used to evaluate the effects of Seunggaltang. Statistical analysis was performed by using paired sample T-test. Statistical significance was achieved if the probability was less than 5%(P<0.05). The result were as follows : 1. Statistically, Seunggaltang didn't showed significant effect on skin humidity, skin sebum, skin transepidermal water loss, skin melanin and skin erythema. 2. Statistically, Seunggaltang showed significant effect on Clinic Index of atopic dermatitis. 3. Statistically, Seunggaltang didn't showed significant effect on total IgE class and number of allergen. 4. Before and after treatment, the results of blood test and urinalysis were normal. Conclusion : We speculate that Seunggaltang has some therapeutic effects in mitigating the symptoms of atopic dermatitis.

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갑상선종에서 발생한 다양한 조직학적 양상을 보인 역형성 암종의 세포학적 소견 - 1예 보고 - (Cytology of Anaplastic Thyroid Carcinoma with Varied Histologic Patterns Arising in Preexisting Goiter - Report of A Case -)

  • 이미자;이미숙;정유경;임성철;기근홍;전호종
    • 대한세포병리학회지
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    • 제6권2호
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    • pp.187-192
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    • 1995
  • Anaplastic carcinoma of the thyroid (ACT) is a rare subtype of thyroid neoplasm. This tumor represents approximately 5-10% of all thyroid malignancies and has poor prognosis ACT often arises on a long-standing thyroid nodule and has been documented to be associated with a variety of more well-differentiated thyroid carcinomas. We experienced a case of anaplastic thyroid carcinoma who had had about a year history of thyroid getter. The patient had been injected with sclerosing agents in treatment of preexisting golfer. The ACT in this case had varied cytologic and histologic appearances: pleomorphic, giant cell, spindle and squamoid. Immunohistochemically, strong cytoplasmic positivity for cytokeratin was seen in all kinds of tumor cells. Ultrastructurally, the evidences of epithelial differentiation were seen such as intercellular junctions and tonofibrils.

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수술장 최적화를 위한 효율적 운영시스템 구축 (The efficient operatiing system construction for the multidemensional optimization of the operating theatre)

  • 백롱민;양진기;양재선;오덕영;강성범;구자원;김재용;김태우;오주한;윤필영;이재호;임청;전용탁;허찬영;홍성규;황정원;김춘옥;김은경;조은주;윤경미;원현경;임세영;문현미;이소영;김해동;김민수;김세진
    • 한국의료질향상학회지
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    • 제14권2호
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    • pp.67-74
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    • 2008
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Determination of pectolinarin in Cirsium spp. using HPLC/UV analysis

  • Cho, Sunghun;Lee, Jaemin;Lee, Yoon Kyoung;Chung, Mi Ja;Kwon, Ki Han;Lee, Sanghyun
    • Journal of Applied Biological Chemistry
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    • 제59권2호
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    • pp.107-112
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    • 2016
  • Pectolinarin was isolated from the ethyl acetate fraction of Cirsium setidens using open column chromatography and was analyzed using spectrometry. Pectolinarin content in Cirsium spp. was determined using HPLC/UV. Pectolinarin content in the aerial part of Cirsium spp. was higher than that in the root and pappus. Pectolinarin content was highest in the aerial part of C. chlorolepis (110.65mg/g extract). Consequently, the aerial part of C. chlorolepis has potential for use in new natural medicinal products, health supplements, and beverages.