A Clinical Research about the Effects of Seunggaltang on Patients with Atopic Dermatitis

승갈탕(升葛湯)을 사용한 아토피 피부염 환자에 대한 임상시험

  • 신상호 (동의대학교 한의과대학 안이비인후피부과학교실) ;
  • 김자혜 (동의대학교 한의과대학 안이비인후피부과학교실) ;
  • 김미보 (동의대학교 한의과대학 안이비인후피부과학교실) ;
  • 윤화정 (동의대학교 한의과대학 안이비인후피부과학교실) ;
  • 유선애 (동의대학교 한의과대학 한방소아과학교실) ;
  • 이승연 (동의대학교 한의학 임상연구센터, 동의대학교 한의과대학 한방소아과학교실) ;
  • 이미연 (삼세한방병원) ;
  • 김규곤 (동의대학교 데이터정보학과) ;
  • 고우신 (동의대학교 한의과대학 안이비인후피부과학교실, 동의대학교 한의학 임상연구센터)
  • Published : 2007.08.25

Abstract

Objective : The purpose of this clinical research was to investigate the effects of Seunggaltang on patients with atopic dermatitis. Methods : Thirteen patients were treated with Seunggaltang and ten patients were treated with placebo for 8 weeks. We observed skin humidity, skin sebum,, transepidermal water loss, skin melanin, skin erythema, total IgE class and number of allergen. And Clinic Index of Atopic Dermatitis(Extent, Intensity, Subjective symptoms, Total score) was used to evaluate the effects of Seunggaltang. Statistical analysis was performed by using paired sample T-test. Statistical significance was achieved if the probability was less than 5%(P<0.05). The result were as follows : 1. Statistically, Seunggaltang didn't showed significant effect on skin humidity, skin sebum, skin transepidermal water loss, skin melanin and skin erythema. 2. Statistically, Seunggaltang showed significant effect on Clinic Index of atopic dermatitis. 3. Statistically, Seunggaltang didn't showed significant effect on total IgE class and number of allergen. 4. Before and after treatment, the results of blood test and urinalysis were normal. Conclusion : We speculate that Seunggaltang has some therapeutic effects in mitigating the symptoms of atopic dermatitis.

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