• Clinical and Experimental Pediatrics
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• 제57권5호
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• pp.211-216
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• 2014

Asthma comprises a heterogeneous group of disorders characterized by airway inflammation, airway obstruction, and airway hyperresponsiveness (AHR). Airway inflammation, which induces AHR and recurrence of asthma, is the main pathophysiology of asthma. The fractional exhaled nitric oxide (FeNO) level is a noninvasive, reproducible measurement of eosinophilic airway inflammation that is easy to perform in young children. As airway inflammation precedes asthma attacks and airway obstruction, elevated FeNO levels may be useful as predictive markers for risk of recurrence of asthma. This review discusses FeNO measurements among early-childhood wheezing phenotypes that have been identified in large-scale longitudinal studies. These wheezing phenotypes are classified into three to six categories based on the onset and persistence of wheezing from birth to later childhood. Each phenotype has characteristic findings for atopic sensitization, lung function, AHR, or FeNO. For example, in one birth cohort study, children with asthma and persistent wheezing at 7 years had higher FeNO levels at 4 years compared to children without wheezing, which suggested that FeNO could be a predictive marker for later development of asthma. Preschool-aged children with recurrent wheezing and stringent asthma predictive indices also had higher FeNO levels in the first 4 years of life compared to children with wheezing and loose indices or children with no wheeze, suggesting that FeNO measurements may provide an additional parameter for predicting persistent wheezing in preschool children. Additional large-scale longitudinal studies are required to establish cutoff levels for FeNO as a risk factor for persistent asthma.

• 한국응용곤충학회지
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• 제47권3호
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• pp.299-301
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• 2008

회양목명나방(Glyphodes perspectalis) 유충은 6 령기를 거치며, 두부는 검고 광택이 있으며, 몸은 황녹색이었다. 유충기간은 평균 24일이었다. 알은 납작하고 둥근 모양으로 잎에 포개진 형태로 산란되었으며 처음에는 투명하였으나, 시간이 지나면서 유백색으로 변하였다. 번데기는 처음에는 연녹색을 띄었으나, 시간이 지나면서 흑갈색으로 변하였고, 번데기기간은 평균 10.5일이었다. 성충은 1년에 2회 발생하였으며, 1화기 성충은 6월초부터 6월말까지 출현하였으며, 2화기 성충의 우화시기는 8월 중순부터 9월초까지였다.

• 한국식품영양과학회:학술대회논문집
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• 한국식품영양과학회 2004년도 Annual Meeting and International Symposium
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• pp.185-197
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• 2004

Type 2 diabetes is characterized by hyperglycemia and hyperinsulinemia, features of insulin resistance. In vivo treatment of ob/ob mice with hydrolyzed fibroin reverses these pathological attributes (6). To explore the mechanism underlying this effect, we have used the 3T3-Ll adipocytes as a cell type which would represent the periphery, in vivo. Exposure of 3T3-Ll adipocytes to chronic insulin leads to the a 50% loss of insulin-stimulated glucose uptake. Chronic exposure to fibroin blocked, in part, the response to chronic insulin but also increased the sensitivity of control cells to the acute action of insulin. The later effect was most robust at physiological concentrations of insulin. Fibroin did not prevent the insulin-induced down-regulation of the insulin receptor or the tyrosine kinase activity associated with the receptor. Further, fibroin had no affect on the loss in activity of the insulin-sensitive down-stream kinase, Akt. Interestingly, fibroin accelerated glucose metabolism and glycogen turnover independent of insulin action. In addition, fibroin up-regulated GLUT1 which increased its expression at the cell surface and caused the redistribution of GLUT4 to the plasma membrane. Together, these later effects would lead to an improvement in hyperglycemia in vivo which would in turn reduce the need for insulin.

• 한국지구과학회지
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• 제26권2호
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• pp.129-136
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• 2005

Continued observation of ARGO floats for years(about 4 years) makes the conductivity sensor more vulnerable to fouling by marine life and associated drift in salinity measurements. In this paper, we address this issue by making use of floats deployed in different years. Floats deployed in the East Sea and the Indian Ocean are examined to find out float-to-float match-ups in such a way that an older float pops up simultaneously with a newer deployment (with tolerable space-time difference). A time difference of less than five days and space difference of less than 100km are considered for the match-up data sets. For analysis of the salinity drift under the stable water mass, observations of the floats from deepest water masses have been used. From the cross-check of ARGO floats in the East Sea and the Indian Ocean, it is found that there is a systematic drift in the older float compared to later deployments. All drift results, consistently show negative bias indicating the typical nature of drift from fouled sensors. However, the drift is much less than 0.01, the specified accuracy of ARGO program.

• 대한인간공학회지
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• 제15권2호
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• pp.37-49
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• 1996

Morningness-Eveningness Questionnaire (MEQ) of Horne & Ostberg(1976) was translated into a Korean version, and MEQ and life habit inventory was administrated with approximately 900 university students. The distribution of MEQ score was normal. Arising time and bedtine for weekdays and holidays came in the order of morning type, intermediate and evening-type. And the deviation for the evening-type was greatest. Also, the deviation of sleep length for the evening-type was greater than the morning- type. There were tendencies that the bed time and arising time of the male were slightly later than those of the female, and the sleep length of the male was a little longer than that of the female. It also appeared that the arising time was later in the male who completed the military services than those who did not in the chronotype. And the sleep length of the non-served male was longer than that of the served one. Such tendencies noticeably appeared especially the evening-type. The evening-type was subject to heavy variability in bedtime. arising time, and sleep length. The sleep latency of the evening- type was longer and mood on arising was worse. And the ratio of nap or light sleep was higher in these subjects than in others. These results suggested that evening-type students had more irregular and/or flexible sleep-wake habits than the morning-type.

• 한국환경과학회지
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• 제22권3호
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• pp.371-378
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• 2013

After identifying species by collecting the suspended and attached algae mat inhabiting in the slow sand-filter, Spirogyra sp., Mougeotia sp. and Closterium sp. were main green algae and Synedra sp. was diatom algae. Among them green algae Spirogyra sp. was dominant species. A result of observing the life mode of apple snail for a month after introducing into the slow sand-filter, apple snail eggs were discovered on the filter walls 2 weeks after introducing, 4 weeks later lots of eggs were observed all of the slow sand-filter walls, it means there is no problem for apple snail to live in the slow sand-filter. The observation result for algae removal potential by introduced apple snail after 2 months later, slow sand-filter where apple snail were introduced, a few algal mat were observed. On the other hand, no introduced apple snail into the slow sand-filter, lots of suspended algal mats were formed in the water and attached algal mats on the sand surface as well, these algal mat induced much of operating problems.

• 성인간호학회지
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• 제19권2호
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• pp.329-337
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• 2007

Purpose: Increasing numbers of Koreans have immigrated to the United States since the late 1960s. The first generation of Korean immigrants or their parents become old and institutionalized in American nursing home setting. Although the Korean elders would experience many cultural differences in the nursing home, no study to date has investigated their everyday lives on how they live through their later lives within a different cultural environment from their own. Methods: Using ethnographic methodology, the purpose of this paper was to illustrate Korean residents' experiences and daily lives in a nursing home located in an east coastal city in the U.S. Participant observation, filed notes, semi-structured interviews were utilized by means of data collection. Eighteen Korean residents were observed, and five of them and two nurses participated in informal qualitative interviews. Results: The overriding theme from the findings is "thrown in a different world." Three sub-themes include "constant struggles in making themselves understood", "dealing with culturally inappropriate nursing care," and "maintaining their own ways of life". Conclusions: The discovered themes reflect culturally isolated lives of the participants and open a venue for designing a culturally congruent nursing care for Korean elders living in the U.S. nursing homes.

• BMB Reports
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• 제39권6호
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• pp.737-742
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• 2006

Open reading frame 60 of Bombyx mori nucleopolyhedrovirus (Bm60) is located between 56,673 and 57,479 bp in the BmNPV genome which encodes 268 amino acid residues with predicted molecular weight of 31.0 kDa. Bm60 and its homologues have been identified in 11 completely sequenced lepidopteran NPVs. The transcript of Bm60 was detected by RT-PCR at 18-72 h post-infection (p.i.), while the corresponding protein could be detected at 24-72 h p.i. in BmNPV-infected BmN cells by Western blot analysis using a polyclonal antibody against Bm60. The expression of Bm60 was inhibited in the presence of Ara-c, an inhibitor of viral DNA synthesis. These results together indicated that Bm60 was a late gene. The size of Bm60 product was found to be a 31 kDa in BmNPV-infected BmN cells, consistent with predicted molecular weight. Immuno-fluoresence analysis showed that the Bm60 product was first detected in the cytoplasm at 24 h p.i and also located in nucleus during later infection. In conclusion, the available data suggest that Bm60 is a functional ORF of BmNPV and encodes a 31kDa protein expressed in the later stage of infection cycle.

• 디자인학연구
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• 제11권1호
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• pp.1-10
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• 1998

중세 유럽에서는 각 지방의 귀족들이 지배하는 독특한 문화와 풍토 속에서 코치빌더에 의해 지역 특색이 나타나 있는 개성 있는 형태의 마차가 제작되었다. 이러한 마차는 구동수단으로써 엔진이 장착되어진 초기 자동차가 등장하는 시기의 차량 형식에 커다란 영향을 미치게 된다. 이후, 가솔린 엔진의 보급으로 자동차는 크기와 무게에서 유연성을 갖게 되며, 성능과 디자인 측면에서 급속한 발전을 가져왔다. 초기 자동차 제작이 시사하는 중요한 점은 기능에 대한 순순한 접근과 시대성을 표현하는 스타일링의 단계적 진보를 이루었다는 것이다. 이러한 발전과정이 배경에는 관련 산업의 진보와 함께 각 지역의 사회적 영향이 자동차의 형태에 반영되어 왔음을 알 수 있다. 본 연구는 대량 동력 화(mass-motorization)된 현대 사회에 있어서 자동차에 대한 무한한 요구와 다양화를 추구하는 시점에서 시간의 영속성과 자동차 디자인이 취해야할 본위를 재고해 볼 수 있는 계기로 삼아보는데 그 의의를 두었다.

• Earthquakes and Structures
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• 제13권4호
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• pp.387-396
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• 2017

The first determination and assessment of the damages to structures after the earthquake is important for preventing increase in loss of life and property that may occur in later times. When rapid damage assessment is performed after an earthquake, damage assessment forms are generally used. The forms that are filled in the field are assessed in the office environment later. In this study, while the process of earthquake damage assessment was being carried out, the ready-made form was moved to web base and the data to be obtained in the field was transferred to the database by means of tablets and smart phones. Keeping earthquake damages in a database will contribute to the studies to be conducted on earthquake and the earthquake regulations to be prepared. Furthermore, emergency damage assessment will be performed faster and more reliably after the earthquake through this study. As the data transferred to the web base is accessible to different people, savings will be provided for both time and personnel. Furthermore, the assessment will have a healthier and scientific basis. In this study, exemplification was conducted for six different reinforced concrete buildings that were damaged during Van earthquake in October 23. With this study, damage assessment procedures can be completed as soon as possible.