• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제47권6호
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• pp.465-470
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• 2021

Few cases of spontaneous bone regeneration after extensive resection of the jaw bone have been reported, but it is more common in young adults or children. In this case, we report spontaneous bone healing in a 73-year-old female patient. On radiological examination, necrotic regions were seen in the right mandible. She was diagnosed with medication-related osteonecrosis of the jaw due to previous bisphosphonate use. After segmental resection, stabilization achieved using a reconstruction plate. The periosteum was preserved during the procedure. Twelve months later, panoramic radiography was taken and bone formation was seen both horizontally and vertically around the plate. If the periosteum is preserved and stabilization is achieved after resection in benign lesions, the bone may regenerate spontaneously regardless of age. Therefore, instead of simultaneous autogenous bone application, such patients may be followed to determine whether spontaneous bone healing will occur. This should improve patient comfort and reduce surgical cost.

• Medical Lasers
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• 제9권1호
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• pp.79-83
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• 2020

This paper reports a case of type 1 posterior glottic stenosis in a 60-year-old woman that was misdiagnosed as bronchial asthma. The patient was intubated at another hospital after ingesting herbicide and extubated seven days later. Although her voice changed, she had not received treatment at that time. She visited a local internal medicine clinic when her condition deteriorated to the point of dyspnea, but several months of treatment for bronchial asthma failed to improve her symptoms. Upon admission to the author's hospital, a laryngoscopic examination revealed a type 1 posterior glottic stenosis, which was removed surgically using a CO₂ laser.

• 한국임상수의학회지
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• 제41권4호
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• pp.223-227
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• 2024

Air accumulation in the cranial cavity is referred to as pneumocephalus. Tension pneumocephalus is a neurosurgical emergency that can cause headaches, seizures, reduced consciousness, and even death owing to increased intracranial pressure. We report a case of tension pneumocephalus. The patient underwent a frontal sinusotomy for a mass invading the frontal sinus and nasal cavity. One month later, the patient was admitted to the emergency room with seizures and neurotic symptoms, and computed tomography (CT) revealed tension pneumocephalus with significant gas dilatation of both lateral ventricles. Prompt treatment of the dural defect resulted in the immediate improvement of neurological signs. A CT re-examination 1 week after surgery showed that the pneumocephalus had completely resolved. Tension pneumocephalus should be considered a potential complication in patients with worsening neurological signs after skull base surgery. An accurate diagnosis requires an understanding of imaging features and a high index of suspicion, and immediate intervention is essential.

• 식물병연구
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• 제13권1호
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• pp.34-39
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• 2007

지난 수년간 전남 소록도에서 관상용으로 관리되던 철쭉나무들이 고사되기 시작하였고, 고사된 철쭉나무에 다량의 지의류가 정착 번성하고 있다는 보고를 접하고, 철쭉나무의 고사와 지의류의 병원성에 대한 관계 규명을 위하여 본 조사를 실시하게 되었다. 이를 위하여 지금까지 문헌에 보고된 식물병원성 가능 인자에 대하여 조사하기 위하여 지의류형성곰팡이 균사의 식물체 감염 여부, 공생조류에 의한 병원성 여부, 지의체 대사산물에 의한 식물체 피해 여부에 대하여 검증을 실시하였다. 지의류가 정착된 철쭉나무 가지를 절편하여 분별염색을 실시하여 조직을 관찰한 결과, 고사된 조직 내에 지의류형성곰팡이 균사의 직접적인 감염을 확인할 수 없었으며, 공생조류를 분리하여 인위적으로 접종한 결과, 공생조류가 식물체 조직 내에서 생존하고 있음에도 불구하고 뚜렷한 병발생이나 병징이 나타나지 않았다. 지의류 대사물질에 의한 식물조직의 피해를 알아보기 위하여 지의류 추출액을 처리한 결과에서도 뚜렷한 병징 발생 유도나 조직 피해가 관찰되지 않았다. 따라서 본 실험 결과로 지의체가 직접적으로 식물병을 일으키는 것으로 보기는 어렵다는 결론을 낼 수 있었으며 식물체 고사와 지의류의 번성간의 인과 관계에 대한 고찰을 하였다.

• 대한견주관절학회:학술대회논문집
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• 대한견주관절학회 2005년도 제13차 춘계학술대회
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• pp.107-111
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• 2005

29세의 남자 환자는 내원 2년전부터 견관절 심부의 간헐적인 동통과 근력약화 증상을 보이다가 내원 2개월전부터 지속적이고 심한 견관절 통증 및 야간통을 주소로 내원하였다. 이학적 검사, MRI검사 및 근전도 검사로 결절종에 의한 상견갑 신경 포착증후군으로 확진되었으며 관절경하에서 후상방 관절낭부위를 탐침하여 관절낭 절개술을 시행하여 결절종 제거수술을 시행하였다. 이때 관절경 소견상 후상방 관절와순은 정상소견을 보였으며 SLAP병변은 관찰되지 않았다. 그후 환자는 큰 불편함은 없었으나 술후 2년 경과후에 외전 및 외회전시 나타나는 통증 및 경도의 견관절 후방부 통증을 주소로 내원하여 MRI검사를 시행하였다. 이때 결정종의 재발은 관찰되지 않았으나 SLAP 병변이 의심되어, 관절경검사를 시행한후 SLAP 병변 봉합술을 시행하였다. 현재 환자는 술후 6개월째로 만족스러운 상태로 직업에 복귀한 상태이다.

• Parasites, Hosts and Diseases
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• 제32권1호
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• pp.13-18
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• 1994

간흡충은 담관내에 기생하면서 만성적 감염의 결과 최종적으로 담관암을 유발시키는 것으로 알려져 왔다. 실험동물에서 간흡충의 감염만으로는 담관암이 발생하지 않으며, 어떠한 외적 혹은 내적 발암성의 물질들과 병합하여 담관암이 형성하는 것으로 보고된 바 있다 본 실험은 햄스터에서 간흡충의 감염과 dimethylnitrosamine(DMN)의 병합작용으로 담관암이 발생되었다는 모델을 이용하여 "발암기전의 2단계이론" 상에서 간흡충의 역할을 밝혀보고자 하였다. 총 90마리의 햄스터를 15 마리씩 6군으로 나누었다. $DMN{\;}{\rightarrow}{\;}CS$군의 햄스터에서는 먼저 15 ppm의 DMN을 4주 동안 음수 투여하고, 1주 후에 간흡충을 15마리씩 인공감염시켰다. 그리고 5주 후에 piaziquantel로 간흡충을 치료하였다 $CS{\;}{\rightarrow}{\;}DMN$군에서는 먼저 간홉충을 감염시키고 5주 후에 praziquantel로 치료하였으며 1주 후부터 DMN을 4주동안 투여하였다. DMN + CS군에서는 DMN과 간흠충을 동시에 투여하였으며 4주 후에는 DMN을 제거하였다. DMN군과 CS군은 각각 DMN과 간흡충만을 투여하였고 대조군은 아무것도 투여하지 않았다. 모든 실험동물은 13주 후에 부검하였으며 조직병리학적인 방법으로 간장을 검경하여 진단하였다. 실험결과 담관암은 $DMN{\;}{\rightarrow}{\;}CS$군에서 3마리, DMN + CS군에서 11마리가 발생하였으며 나머지 군들에서는 암이 발생하지 않았다. 본 실험으로 2단계 발암기 전상에서 간흡충은 담관암발생을 촉진하는 효과를 보였음을 알수 있었다.

• Archives of Plastic Surgery
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• 제37권2호
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• pp.178-181
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• 2010

Purpose: Retronychia is the embedding of the nail into proximal nail fold. Retronychia starts with disruption of the longitudinal growth of the nail. With the growth of a new nail, the old one is pushed upwards and backwards. This leads to embedding of the top nail into the ventral aspect of the proximal nail fold and results with chronic paronychia. We present a case of retronychia that was rarely reported in the literature. Methods: A 46-year old female presented with a 3-month history of painful right first, 2nd, 3rd toenail changes. Although she was initially treated with broad spectrum antibiotics, she did not response to therapy. Later, she presented to our department because of progressively worsening pain that impaired her walking. Physical examination revealed with proximal nail fold erythema, painful swelling, yellowish nail discoloration, and distal onycholysis. Bacterial and fungus culture showed no organism. Treatment was surgical nail avulsion under local anesthesia. Results: The postoperative course was uneventful. 10 months later, the patient had a normal growing nail and was free of symptoms. Conclusion: We report a case of retronychia on toenail. Retronychia is a proximal nail plate ingrowth into the proximal nail fold which is associated with multiple generations of nail plate misaligned beneath the proximal nail. Management consisted of simple avulsion of superimposed nail. Retronychia is suspected with a persistent paronychia, particularly in the setting of trauma. Avulsion of the top nail confirms the diagnosis and may be curative if the underlying nail appears healthy.

• Journal of the Korean Association of Oral and Maxillofacial Surgeons
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• 제42권5호
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• pp.301-306
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• 2016

The purpose of this study is to report a rare case of mandibular adenocarcinoma that was diagnosed due to metastasis from the prostate. Numb chin syndrome (NCS), which was associated with this case, is also discussed. Computed tomography (CT) and an intraoral incisional biopsy of the left mandibular area were performed. Urology consultation, hormone therapy, chemotherapy and follow-up radiographic images were administered. Histological examination of the incised specimen revealed moderately differentiated adenocarcinoma. The Gleason score was 8 (primary 4/secondary 4). Immunohistochemical features and radiographic results confirmed the diagnosis of metastasis from prostate adenocarcinoma, moderately differentiated. The patient's prostate-specific antigen (PSA) level was very high. After hormone treatment, the patient's PSA levels dropped gradually. Seventeen months later, in May 2015, the PSA level was elevated. The 18-month follow-up CT image indicated that the patient's condition was aggravated. Docetaxel chemotherapy was started in June 2015 (18 months later), and the sixth cycle of the therapy is in progress. Oral metastases that originate from prostate adenocarcinoma are rare and can induce various periosteal reactions. Hormone therapy, chemotherapy and close follow-up could be additional, appropriate treatment, and were applied in this case. Finally, NCS is a valuable indicator of metastatic disease in the mandible.

• Archives of Plastic Surgery
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• 제36권4호
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• pp.507-511
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• 2009

Purpose: Adenoid cystic carcinoma (ACC) is a rare malignant epithelial neoplasm derived from the salivary glands. In some cases, ACC may arise in other primary sites, such as skin. We report a case of adenoid cystic carcinoma arising the scalp skin of 69 - year - old woman. Methods: A 69 - year - old woman presented with a tender scalp nodule. A local wide excision was performed. Histopathologic examination was revealed the adenoid cystic carcinoma with basaloid cells in a cribriform pattern. The resection margins were free of tumor. Two years later a tumor recurred in the scarred area. The lesion was removed surgically and the histopathological diagnosis of adenoid cystic carcinoma was again established. After two years, tumor recurred again and diatant metastasis of the lung was diagnosed. A surgical wide excision was done and the close regular follow - up for recurrence was done. Two years later, third recurrence of the scalp was observed. We also performed the wide local excision with tumor free margin. Results: We experience the recurrent adenoid cystic carcinoma of the scalp with pulmonary metastasis. We have performed the wide local excision for three times. The patient has been followed up for 10 years with regular work - up for recurrence and metastasis Conclusion: primary cutaneous adenoid cystic carcinoma is a rare skin neoplasm with a high potential for recurrence after local excision. The standard treatment of ACC is wide local excision with tumor - free margins established by permanent section.

• Clinical and Experimental Pediatrics
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• 제46권2호
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• pp.192-194
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• 2003

가정분만으로 태어난 후 생후 6일된 신생아에서 전신성 강직-간대 경련이 발생하여 내원한 환아에서, 병력과 진찰 소견상 신생아 파상풍으로 진단하여 근이완제 및 인공환기요법으로 치료한 1례를 경험하였기에 보고하는 바이다.