• Journal of the Korean Society for Precision Engineering
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• v.23 no.8 s.185
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• pp.178-184
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• 2006

Hot embossing is to fabricate desired pattern on the polymer substrate by pressing the patterned mold against the substrate which is heated above the glass transition temperature, and it is a high throughput fabrication method for bio chip, optical microstructure, etc. due to the simultaneous large area patterning. However, the bad pattern fidelity in large area patterning is one of the obstacles to applying the hot embossing technology for mass production. In the present study, PDMS pad was used as a cushion on the backside of the micro-patterned 4 inch Si mold to improve the pattern fidelity over the 4 inch PMMA sheet by increasing the conformal contact between the Si mold and the PMMA sheet. The pattern replicability improvement over 4 inch wafer scale was evaluated by comparing the replicated pattern height and depth for PDMS-cushioned Si mold against the rigid Si mold without PDMS cushion.

• Journal of the Korea Society for Simulation
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• v.22 no.4
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• pp.139-147
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• 2013

This paper proposes a novel method for feature selection for mass spectrometric proteomic data based on Random Forest. The method includes an effective preprocessing step to filter a large amount of redundant features with high correlation and applies a tournament strategy to get an optimal feature subset. Experiments on three public datasets, Ovarian 4-3-02, Ovarian 7-8-02 and Prostate shows that the new method achieves high performance comparing with widely used methods and balanced rate of specificity and sensitivity.

• Journal of the Korean Dietetic Association
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• v.13 no.2
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• pp.157-168
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• 2007

The purposes of this study were to measure the resting metabolic rate(RMR) of 30-40 year old women and to compare it with values predicted using published equations. Body weight, height and body fat of subjects were measured. RMR was measured by two indirect calorimeter(method 1 and method 2). RMR was predicted using various equations. Average height, weight and body fat(%) of subjects were 158.6cm, 59.1kg and 30.9%, respectively. The RMR(1621.2$\pm$301.5 kcal/day) measured by portable indirect calorimeter(method 2) was significantly higher than RMR(1447.4$\pm$223.6 kcal/day) measured by typical indirect calorimeter(method 1). Comparison of measured RMR with predicted RMRs suggested that there was a least difference in RMR predicted by equation of Cunningham. According to RMSPEs(Root Mean Squared Prediction Errors), equations of Cunningham and body surface area were found to predict measured RMR(by method 1) most accurately (within 239.1kcal/day and 232.9kcal/day, respectively). The fat free mass and fat mass - adjusted correlation showed that measured RMR(by method 1) had negative relationships with muscle mass(r = -0.873) and fat free mass(r = -0.866). The equations of Cunningham and body surface area provide relatively accurate estimates of RMR when determining energy needs of 30-40 aged women. There are needs for development of RMR predicted equations that are derived from large samples of Korean.

• Journal of the Korea Institute of Information and Communication Engineering
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• v.11 no.10
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• pp.1880-1885
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• 2007

In this paper, we propose the method that improve the performance of the Mowse. Mowse is the tool of the peptide mass fingerprinting that is used the identification of protein. In Mowse, frequency factor matrix is generated to regular interval for protein and peptide mass and the value of each elements is calculated to frequency of peptide. We propose new method for calculation of exact scoring value maintaining same size of matrix. The proposed method is that decide interval of matrix considering distribution of protein database. That is, interval of matrix is decided to small in many value of protein mass and is decided to large in few value of protein mass. We present the performance result both Mowse scoring method and the proposed scoring method.

• Transactions of the Korean Society of Mechanical Engineers B
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• v.30 no.6 s.249
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• pp.497-504
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• 2006

A Coriolis mass flowmeter(CMF), which has U-Shaped unique measurins tube was developed fo. direct mass flow measurement. In order to convert the time difference between two measuring tubes motion into mass flowrate and flow quantity, a signal processing circuit, as a part of CMF, was also developed. The CMF was designed as the 15 mm nominal diameter of pipe connection and the 8 mm stainless steel(sus 316) pipe was used for measuring tube. To maximize the flow signal(time difference) from the measuring tubes, the natural frequency of measuring tube was adjusted as 220 Hz, which is same as the frequency of exciter. The maximum displacement at the end of the measuring tube was measured as 0.05 mm and the maximum time difference between two measuring tubes was observed as $20{\mu}s$, which was proper for discrimination and measuring range of CMF. The developed CMF was tested against the gravimetric flowmeter calibrator in the range of 3 kg/min and 30 kg/min. The results showed that the CMF has good linearity and repeatability in the tested flow range. Large size of CMF base on the current study experience will be developed.

• Proceedings of the Korean Institute of Building Construction Conference
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• 2017.05a
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• pp.127-128
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• 2017

Tests are conducted according to the ISO TS 16774, Part 3 standard for quality management of leakage repair materials used in cracks in underground concrete structures. These test methods are performed indirectly using a nonwoven fabric on a chalet containing leak repair materials. However, it is considered that it is appropriate to verify the resistance of the repair material, which is required to be applied directly to the cracks in the actual field and to exhibit the resistance of the flow velocity. In this study, mass change was measured by using nonwoven fabric and nonwoven fabric. As a result, both methods showed an increase in mass, which indicated that the maintenance material itself contained a large amount of water, and that the mass change occurred depending on the drying state. Also, depending on the use of nonwoven fabric, the error due to the indirect test could not be ruled out. Therefore, further verification is needed, and it is considered that the test for change of mass reduction measurement is necessary according to the drying time of other types of the same series.

• Proceedings of the Korean Society for Noise and Vibration Engineering Conference
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• 2007.05a
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• pp.641-648
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• 2007

Computational rotor dynamic analyses of designed composite roller for large LCD panel manufacturing process have been conducted. The present computational method is based on the general finite element method with rotating gyroscopic effects. General purpose commercial finite element code, with special rotordynamics analysis module is applied. For the purpose of numerical verification, comparison study for a benchmark dual rotor model with support bearings is also presented. Detailed finite element models for composite roller with different length are constructed and analyzed considering gravity effect in order to investigate vibration characteristics in actual operation environment. As results of the present study, rotor stability diagrams and mass unbalance responses are presented for different rotating conditions.

• Journal of the Semiconductor & Display Technology
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• v.6 no.1 s.18
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• pp.1-6
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• 2007

In order to raise productivity of the OLED and realization of the OLED TV, the enlargement of the mother glass substrate is required. The large-size glass substrate has some difficulties regarding its deflection during handling operation due to its thin thickness (0.5$\sim$0.7t) which is not even enough to stand its mass itself. This paper is demonstrating a new solution of this difficult through clamping and bending boundary condition, which helps to minimize the deflection of the glass substrate. Based on the developed method, the experiments had been done for verifying the proposed method to minimize the glass-deflection. With the developed method, the new design of glass substrate handler can be proposed to allow the large OLED displays be manufactured.

• Wind and Structures
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• v.20 no.3
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• pp.423-448
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• 2015

In this paper the unsteady fluid-structure interaction (FSI) problems with large structural displacement are solved by partitioned solution approaches in the arbitrary Lagrangian-Eulerian finite element framework. The incompressible Navier-Stokes equations are solved by the characteristic-based split (CBS) scheme. Both a rigid body and a geometrically nonlinear solid are considered as the structural models. The latter is solved by Newton-Raphson procedure. The equation governing the structural motion is advanced by Newmark-${\beta}$ method in time. The dynamic mesh is updated by using moving submesh approach that cooperates with the ortho-semi-torsional spring analogy method. A mass source term (MST) is introduced into the CBS scheme to satisfy geometric conservation law. Three partitioned coupling strategies are developed to take FSI into account, involving the explicit, implicit and semi-implicit schemes. The semi-implicit scheme is a mixture of the explicit and implicit coupling schemes due to the fluid projection splitting. In this scheme MST is renewed for interfacial elements. Fixed-point algorithm with Aitken's ${\Delta}^2$ method is carried out to couple different solvers within the implicit and semi-implicit schemes. Flow-induced vibrations of a bridge deck and a flexible cantilever behind an obstacle are analyzed to test the performance of the proposed methods. The overall numerical results agree well with the existing data, demonstrating the validity and applicability of the present approaches.

• Mass Spectrometry Letters
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• v.6 no.4
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• pp.85-90
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• 2015

This article reviews recent analytical techniques using inductively coupled plasma-mass spectrometry (ICP-MS) immunoassay for clinical and bio analysis. We classified the techniques into two categories, direct and indirect analysis, which depend upon a guideline of whether tagging materials are used or not. Direct analysis is well known, and generally used in conjunction with various other techniques, such as laser ablation, chromatographic separations, etc. Recently, indirect analysis using tagging elements has intensively been discussed because of its importance in future applications to bio and clinical analysis, including environmental and food industries. The method has shown advantages of multiplex detection, excellent sensitivity, and short analysis time owing to signal amplification and magnetic separation. Now, it expands the application field from small biomolecules to large cells.