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http://dx.doi.org/10.6109/jkiice.2007.11.10.1880

Performance Improvement of Mowse Scoring Method for Protein Identification  

Jung, Min-A (목포대학교 컴퓨터교육과)
Kim, Chi-Yeon (목포해양대학교 해양전자통신공학부)
Publication Information
Journal of the Korea Institute of Information and Communication Engineering / v.11, no.10, 2007 , pp. 1880-1885 More about this Journal
Abstract
In this paper, we propose the method that improve the performance of the Mowse. Mowse is the tool of the peptide mass fingerprinting that is used the identification of protein. In Mowse, frequency factor matrix is generated to regular interval for protein and peptide mass and the value of each elements is calculated to frequency of peptide. We propose new method for calculation of exact scoring value maintaining same size of matrix. The proposed method is that decide interval of matrix considering distribution of protein database. That is, interval of matrix is decided to small in many value of protein mass and is decided to large in few value of protein mass. We present the performance result both Mowse scoring method and the proposed scoring method.
Keywords
Mowse;
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  • Reference
1 M. R. Wilkins, K. L. Williams, R. D. Appel, and D. F. Hochstrasser, Proteom Research: New Frontiers in Fuctional Geomics, Springer-Verlag
2 Zhang, W. and Chait, B. T., 'ProFound - An expert system for protein identification using mass spectrometric peptide mapping information,' Anal. Chem., 72(11), 2000, pp.2482-2489   DOI   ScienceOn
3 P. R. Baker and K. R. Clauser, 1995. http://prospector.ucsf.edu
4 M. R. Wilkins, E. Gasteiger, C. Wheeler, I. Lindskog, J. C. Sanchez, A. Bairoch, R. D. Appel, M. D. Dunn, and D. F. Hochstrasser, 'Multiple parameter cross-species protein identification using MultiIdent, Electrophoresis, 19(18), 1998, p.3199-3206   DOI   ScienceOn
5 M. R. Wilkins, E. Gasteiger, A. Bairoch, J. C. Sanchez, K. L. Williams, R. D. Appel, and D. F. Hochstrasser, Protein Identification and Analysis Tools in the ExPASy Server in: 2-D Proteom Analysis Protocols, 1998, Humana Press
6 G. Kris and Joel Vandekerckhove, 'Protein identification methods in proteomics,' Electrophoresis, 21, 2000, pp.1145-1154   DOI   ScienceOn
7 Tang, C., Zhang, W., Fenyo, D., and Chait, B. T., 'Assessing the performance of Different Protein Identification Algorithms,' 48th ASMS Conference, June 11-15, 2000
8 Perkins, D. N., Pappin, D. J. C., Creasy, D. M. and Cottrell, J. S., 'Probability-based protein identification by searching sequence databases using mass spectrometry data,' Electrophoresis, 20, 1999, pp.3551- 3567   DOI   ScienceOn
9 C. L. Daniel, Introduction to Proteomics, Humana Press
10 S. R. Penningron and M. J. Dunn, Proteomics From Protein Sequence To Function, 2001. Springer-Verlag
11 Pappin, D. J. C., Hojrup, P., and Bleasby., 'Rapid Identification of Proteins by Pepide-Mass Fingerprinting,' Current Biology, 3, 1993, pp.327-332   DOI   ScienceOn