• 대한의생명과학회지
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• 제21권1호
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• pp.32-39
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• 2015

High-risk (HR) human papillomavirus (HPV) genotypes are strongly associated with cervical cancer, whereas other HPV genotypes are not. To identify the various HPV genotypes in clinical samples, we conducted HPV genotyping using a DNA chip test and reverse blot hybridization assay (REBA) in normal cytology samples and atypical squamous cells of undetermined significance (ASCUS) cytology samples. We also investigated the HPV infection rate and HPV genotype prevalence in women with normal cytology and ASCUS cytology. Liquid-based cytology preparations were used for the initial screening of 205 subjects with normal cytology and ASCUS cytology. The HPV infection rate was 49.8% when using the DNA chip assay and 61.0% when using the REBA test. In patients with normal cytology, the HR-HPV positive rate was 21.9% with the DNA chip assay and 43.9% with the REBA test. In contrast, 8.3% of patients with ASCUS were HR-HPV positive when using the DNA chip assay, and 13.6% were positive when tested with the REBA test. The infection rate of HR-HPV in the 40~50-year age group was significantly higher than that of the other age groups. Based on the cytological analysis of the normal and ASCUS samples, the five most prominent HPV genotypes were HPV 16, 18, 68, 33, and 58 using the DNA chip test, and they were HPV 16, 18, 53, 33, and 66 when using the REBA test. In conclusion, the findings show that the results of the REBA test are comparable to those of the DNA chip test. Most strikingly, the REBA test detected the HR-HPV genotype associated with cervical carcinoma similar to that detected with the DNA chip method. Therefore, the REBA test is a useful method to detect clinically important HR-HPV genotypes.

• 대한임상검사과학회지
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• 제51권1호
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• pp.93-104
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• 2019

본 연구는 국내의 진단검사의학과의 검사현황 및 인력배치현황과 검사 건수를 파악하기 위함이다. 지역별, 규모별 임상병리사를 대상으로 설문조사를 실시하여 최종 441부를 분석 자료로 사용하였다. 자료의 분석은 STATA (version 12.0)를 이용하여 Descriptive statistics analysis, Chi-square test, ANOVA test를 실시하였다. 병원 규모별 임상병리사 분포는 의원급 5.8명, 병원급 14.9명, 종합병원 25.8명, 대학병원 45.4명으로 나타났다. 부서별검사건수, 1인 1일 검사건수는 의원, 병원, 종합병원, 대학병원간의 유의한 차이가 있었다. 임상병리사의 1일 검사건수와 1일 적정 검사건수의 차이는 상급병원으로 갈수록 감소하는 것으로 나타났다. 정도관리는 상급병원의 부서별 정도관리 평균 시간은 2시간 이내로 나타났다. 급여만족도, 근무환경만족도, 검사성취도, 복지제도측면에서 의원, 병원급에서 불만족도 다수 차지하는 것으로 나타났다. 이는 선진국형 의료 수준에 맞는 신뢰성 있는 검사의 데이터를 제공하기 위해 임상 병리사의 근무환경에 따른 근무의 만족도와 임상검사의 정확도를 높이기 위해서라도 임상병리사의 처우개선에 초점을 맞추어야 할 것으로 사료된다.

• 대한전기학회:학술대회논문집
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• 대한전기학회 1995년도 하계학술대회 논문집 C
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• pp.1275-1277
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• 1995

We designed and constructed an extremly high power s-band traveling wave resonator for the test of high power microwave components using 80MW pulsed klystron with $4{\mu}s$ pulse width. The 10dB directional coupler for the input power coupling was used, and the ring consists of phase shifter, tuner, H-band, and other microwave components. The designed total electrical length of the system is 10 times of the waveguide wavelength, ${\lambda}_g$=15.3cm, and the measured total insertion loss is 0.15dB. The low power test measurment showed the power multiplication of 14.69. The design goal is to achieve the peak power of 300MW, pulse width $4{\mu}s$ with 30 pulse repetition rate. In this article we discuss the treveling wave resonant ring constructed at the PAL laboratory together with the test results.

• Nuclear Engineering and Technology
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• 제56권2호
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• pp.655-665
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• 2024

The objective of the present experimental study is to investigate the effect of inlet throttling on the thermohydraulic stability of a large scale water-based Reactor Cavity Cooling System (RCCS). The test was performed using the water-based Natural convection Shutdown heat removal Test Facility (NSTF) at Argonne, which represented a ½ axial scale and 12.5° sector slice of the full scale Framatome 625 MW_t SC-HTGR RCCS concept. A two-phase steady state was first established through direct condensate refill, followed by increased inlet throttling over 10 stages, corresponding to a loss coefficient K over the range of 0.05-653. With the inlet throttling gradually increased, the system experienced a unique transition process between stabilization and destabilization. Through a stability analysis, three instability mechanisms were identified in the present test, including a compound mechanism due to both natural circulation oscillations (NCOs) and density wave oscillations (DWOs), Type-II DWOs, and geysering.

• 한국신뢰성학회지:신뢰성응용연구
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• 제13권4호
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• pp.299-307
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• 2013

The value of blood sugar is measured by a personal blood glucose meter which consists of two parts: a glucose strip and a blood glucose meter. A personal blood glucose meter makes use of electric media which are composed of glucose oxidase and electron. This study is to propose a method of reliability demonstration test derived from field data analysis and FMEA(Failure Mode and Effect Analysis). Detailed Conditions for reliability demonstration test are selected from the comparison of various failure mechanisms. The most dominant failure mechanism is wear-out which is caused by strip insertion/extraction. The testing device that can reproduce the failure mechanism of strip insertion/extraction is made to conduct reliability demonstration test. Using the testing device, it is confirmed that target lifetime of selected devices is more than 2 years.

• 한국동물위생학회지
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• 제24권1호
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• pp.69-82
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• 2001

The result of studying the pathogenicity of Salmonella typhimurium and S enteritidis isolated from domestic animals in Gyeongbuk province were summarized as follows. In Congo-red binding test, S typhimurium had much more rough types than S enteritidis. In colicin production test, 4 strains of S typhimurium were positive but all of S enteritidis were negative. In hemolysin production test, all of S typhimurium and S enteritidis were negative. In Guinea pig serum resistant test, all of S typhimurium and S enteritidis were positive. As a result of pathogenicity test to mice, 54.4% of mice were died. Therefore, S typhimurium and S enteritidis were considered as highly pathogenic. S typhimurium DT104 and S enteritidis PT4 were more pathogenic to mice than other phage types of same serovar. S typhimurium and S enteritidis were considered not so pathogenic for 6-day-old chickens. The recovery rates of Salmonella stains from mice and chickens inoculated were 96.8%, and 54%, respectively. In chickens, proportional to the time from 2 weeks after challenge inoculation, the recovery rates were noticeably decreased.

• 한국동물위생학회지
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• 제20권2호
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• pp.205-215
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• 1997

In this study, homogenized mixture of tubercle and pulmonary lymph node showed up tuberculin(PPD) positive dairy cattle was inoculated in experimental animal, and was cultured on medium(Lowenstein Jensen medium, 3% Ogawa). The results obtained through the survey were sumerized as follows ; 1. In experimental animal, goat and rabbits were decreased body weight(25∼28%) and died in 90 days with severe pathogenicity. Rats are slight pathogenicity. 2. Goat, rabbits and rats showed up severe lesions In lung, rabbits was also lesions other organs (kidney, appendix, ileocecum, and I lymph node). 3. Mycobacterium was grown between 5 weeks and 8 weeks on Lowenstein Jensen medium and 3% Ogawa medium. 4. Biochemical test of Mycobacterium cultured on medium was that niacin, nitrate reduction, tween 80 hydrolysis and catalase test were negative, but that urease test was positive. Therefore it was Mycobacterium bovis (M. bovis).

• 한국항공우주학회지
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• 제44권2호
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• pp.156-164
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• 2016

우주기반기술 검증용 극초소형 위성 STEP Cube Lab.(Cube Laboratory for Space Technology Experimental Project)의 주요 탑재체인 집광형 프레넬렌즈가 적용된 고효율 집광형 태양전력시스템, 열선 절단방식이 적용된 무충격 구속분리장치 그리고 MEMS 기반의 고체추력기에 대해 인증수준의 열진공 시험과 열평형 시험을 수행하였다. 이를 통해 열진공 환경 하의 인증수준의 시험온도규격에서 탑재체의 구조건전성 및 정상작동성을 검증하고, 열평형 시험 결과로부터 보다 신뢰성 높은 보정된 열해석 모델을 확립하였다. 본 논문에서는 주요 임무 탑재체의 인증수준의 열환경 시험에 대한 기능시험 결과 및 시험 결과로부터 수행된 열모델 보정과 최종 열모델의 궤도 열해석 결과에 대해 기술하였다.

• Advances in Traditional Medicine
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• 제3권2호
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• pp.63-71
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• 2003

The psycho-pharmacological effect of BRHAT VATACHINTAMANI RASA (BVC) an Ayurvedic preparation was investigated, both in animal and clinical models. It was observed that BVC possess a sedative or quitening effect in that it significantly decreased the spontaneous motor activity, and also lowered the exploratory behavior of the amphetamine treated animals. This was further evident by increase in climbing out time and taming effect on animal in isolation induced aggression test. Apart from very high dose it seems have little effect on pentobarbital sleeping time and narcotic analgesic test. The drug BVC increases performance of the animal in forced locomotor test. The effect of VATACHINTAMANI RASA on clinical study was not significant.

• 한국지반환경공학회 논문집
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• 제12권12호
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• pp.47-54
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• 2011

점성토 지반의 거동은 압축성뿐만 아니라 투수특성에 크게 영향을 받으며, 특히, 투수특성은 흙의 특성, 이방성에 따라 다르게 나타난다. 투수계수는 주로 실내 압밀시험과 현장 피에조 콘 시험으로부터 산정이 가능하다. 피에조 콘에 의한 투수계수 산정방법은 과잉간극수압의 소산시험 결과로부터 추정할 수 있다. 본 논문에서는 간극수압 소산시험 및 실내시험결과(Oedometer test)를 이용하여 기존의 투수성 평가에 이용되는 이론 해들의 적용성을 검토하고자 하며, 점성토지반 특성에 따른 ${k_{h}/k_{v}}$의 변화를 파악하여 원위치 ${k_{h}/k_{v}}$를 합리적으로 추정할 수 있는 적합한 해를 선정하였다. 연구대상지반은 경남 양산물금 지역의 점성토층이며 원위치 시험인 피에조 콘 소산시험과 비교란 시료에 대한 실내압밀시험(Oedometer test)을 실시하고 각 투수계수 추정해 별로 비교 분석을 실시하였다. 연구결과 피에조 콘 소산시험으로 산정된 투수계수비가 5.85로 나타나 실내시험(Rowe cell/Oedometer)으로 산정된 투수계수비 5.28과 매우 유사한 값을 나타냈다.