• Title/Summary/Keyword: Labeled Data

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Blood culture contamination in hospitalized pediatric patients: a single institution experience

  • Min, Hyewon;Park, Cheong Soo;Kim, Dong Soo;Kim, Ki Hwan
    • Clinical and Experimental Pediatrics
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    • v.57 no.4
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    • pp.178-185
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    • 2014
  • Purpose: Blood culture is the most important tool for detecting bacteremia in children with fever. However, blood culture contamination rates range from 0.6% to 6.0% in adults; rates for young children have been considered higher than these, although data are limited, especially in Korea. This study determined the contamination rate and risk factors in pediatric patients visiting the emergency room (ER) or being admitted to the ward. Methods: We conducted a retrospective chart review of blood cultures obtained from children who visited Yonsei Severance Hospital, Korea between 2006 and 2010. Positive blood cultures were labeled as true bacteremia or contamination according to Centers for Disease Control and Prevention/National Healthcare Safety Network definitions for laboratory-confirmed bloodstream infection, after exclusion of cultures drawn from preexisting central lines only. Results: Among 40,542 blood cultures, 610 were positive, of which 479 were contaminations and 131 were true bacteremia (overall contamination rate, 1.18%). The contamination rate in the ER was significantly higher than in the ward (1.32% vs. 0.66%, P<0.001). The rate was higher in younger children (2.07%, 0.94%, and 0.61% in children aged <1 year, 1-6 years, and >6 years, respectively). Conclusion: Overall, contamination rates were higher in younger children than in older children, given the difficulty of performing blood sampling in younger children. The contamination rates from the ER were higher than those from the ward, not accounted for only by overcrowding and lack of experience among personnel collecting samples. Further study to investigate other factors affecting contamination should be required.

A Data Type for Concept-Based Retrieval against Image Databases Indefinitely Indexed (불확정적으로 색인된 이미지 데이터베이스를 개념 기반으로 검색하기 위한 자료형)

  • Yang, Jae-Dong
    • Journal of KIISE:Databases
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    • v.29 no.1
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    • pp.27-33
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    • 2002
  • There are two significant drawbacks in triple image indexing; one is that is cannot support concept-based image retrieval and the other is that it fails to allow disjunctive labeling of images. To remedy the drawbacks, we propose a new technique supporting a concept-based retrieval against images indexed by indefinite fuzzy triples (I-fuzzy triples). The I-fuzzy triples allow not only a disjunctive image labeling, but also a concept-based matching against images labeled disjunctively. The disjunctive labeling is based on the expended closed world assumption and the concept-based image retrieval is based on fuzzy matching. In this paper, we also propose a concept-based query evaluation against the image database to extract desired answers with the degree of certainty $\alpha$$\in$[1,0].

Indexing and Storage Schemes for Keyword-based Query Processing over Semantic Web Data (시맨틱 웹 데이터의 키워드 질의 처리를 위한 인덱싱 및 저장 기법)

  • Kim, Youn-Hee;Shin, Hye-Yeon;Lim, Hae-Chull;Chong, Kyun-Rak
    • Journal of the Korea Society of Computer and Information
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    • v.12 no.5
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    • pp.93-102
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    • 2007
  • Metadata and ontology can be used to retrieve related information through the inference mure accurately and simply on the Semantic Web. RDF and RDF Schema are general languages for representing metadata and ontology. An enormous number of keywords on the Semantic Web are very important to make practical applications of the Semantic Web because most users prefer to search with keywords. In this paper, we consider a resource as a unit of query results. And we classily queries with keyword conditions into three patterns and propose indexing techniques for keyword-search considering both metadata and ontology. Our index maintains resources that contain keywords indirectly using conceptual relationships between resources as well as resources that contain keywords directly. So, if user wants to search resources that contain a certain keyword, all resources are retrieved using our keyword index. We propose a structure of table for storing RDF Schema information that is labeled using some simple methods.

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Phosphorylation of $Ser^{246}$ Residue in Integrin-linked Kinase 1 by Serum- and Glucocorticoid-induced Kinase 1 is Required to Form a Protein-protein Complex with 14-3-3

  • Chun, Jae-Sun;Kang, Sang-Sun
    • Animal cells and systems
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    • v.9 no.3
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    • pp.161-171
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    • 2005
  • Integrin-linked kinase 1 (ILK1) regulates several protein kinases, including PKB/Akt kinase and glycogen synthase kinase ${\beta}$. ILK1 is also involved distinctively in the cell morphological and structural functions by interacting with the components of the extracellular matrix or integrin. According to the information of serum- and glucocorticoid-induced kinase 1 (SGK1) substrate specificity (R-X-R-X-X(S/T)-${\phi};{\phi}$ indicates a hydrophobic amino acid), two putative phosphorylation sites, $Thr^{181}\;and\;Ser^{246}$, were found in ILK1. We showed that ILK1 fusion protein and two fluorescein-labeled ILK1 peptides, $FITC-^{174}RTRPRNGTLN^{183}$ and $FITC-^{239}CPRLRIFSHP^{248}$, were phosphorylated by SGK1 in vitro. We also identified that 14-3-3 ${\theta}\;{\varepsilon}\;and\;{\xi}$, among several 143-3 isotypes $({\beta},\;{\gamma},\;{\varepsilon},\;{\eta},\;{\sigma},\;{\theta},\;{\tau}\;and\;{\xi})$ formed protein complex with ILK1 in COS-1 cells. Furthermore, the phosphorylation of $Ser^{246}$ by SGK1 induced the binding with 14-3-3. It was also demonstrated that 14-3-3-bound ILK1 has reduced kinase activity. Thus, these data suggest that SGK1 phosphorylates $Thr^{181}\;and\;Ser^{246}$ of ILK1 and the phosphorylation of its $Ser^{246}$ makes ILK1 bind to 14-3-3, resulting in the inhibition of ILK1 kinase activity.

Differences across Types of web Navigation Value and Shopping Mall in Evaluation of website attributes for Apparel Shopping (인터넷 탐색가치와 인터넷 쇼핑물 유형에 따른 의류제품 쇼핑 웹사이트 속성 평가의 차이)

  • 홍희숙
    • Journal of the Korean Society of Clothing and Textiles
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    • v.26 no.5
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    • pp.642-653
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    • 2002
  • The purposes of this studs were 1) to identify web navigation values and classify consumers based on these values and 2) to determine differences between consumer groups and between types of shopping mall in evaluation of website attributes when shopping apparel. The data were collected via a self-administered questionnaire from 204 male and female students who experienced shopping at the website, living in Cheju and analyzed by factor analysis, cluster analysis and t-test. Two factors of navigation value were found and labeled as; information value and entertainment value. Two groups were identified based on navigation value; users of information value (53%) and users of entertainment value (47%). Significant differences between two groups were found in evaluating website attributes selling products of various types regarding apparel products and processes for information search, order and payment. However, for shopping mall website selling only apparel products, differences between two groups were not significant in evaluating most attributes except for two items to evaluate apparel products. Differences between shopping mall types (shopping malls selling products of various types and selling only apparel product) were significant in evaluation of internet users of information value regarding attributes of apparel products while differences between shopping mall types were not significant in evaluation of users of entertainment value regarding all attributes. Internet users of information value showed favor to shopping mall website of department store type chi e internet users of entertainment value showed favor to shopping mall website selling only apparel products.

Various Men's Body Shapes and Drops for Developing Menswear Sizing Systems in the United States

  • HwangShin, Su-Jeong;Istook, Cynthia L.;Lee, Jin-Hee
    • Journal of the Korean Society of Clothing and Textiles
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    • v.35 no.12
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    • pp.1454-1465
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    • 2011
  • Menswear body types are often labeled on garments (to indicate how the garments are designed to fit) with indicators of a size category such as regular, portly, and stout, athletic, or big and tall. A drop (relationships between the chest and waist girths) is related to the fit of a tailored suit. However, current standards are not designed for various drops or body types. There is not enough information of categorizing men's body shapes for the apparel sizing systems. In this article, a set of men's data from SizeUSA sizing survey was analyzed to investigate men's body shapes and drops. Factor analysis and a cluster analysis method were used to categorize men's body shapes. In the results, twenty-five variables were selected through the factor analysis and found four factors: girth factor, height factor, torso girth factor, and slope degree factor. According to the factor and cluster analysis, various body shapes were found: Slim Shape (SS - tall ectomorphy), Heavy Shape (HS - athletic, big & tall, endomorphy and mesomorphy), Slant Inverted Triangle Shape (SITS - regular, slight ectomorphy and slight mesomorphy weight range from normal to slightly overweight), Short Round Top Shape (SRTS - portly and stout, endomorphy). Body shapes were related to fitting categories. SS and HS were related to big & tall fitting category. SITS was related to regular. SRTS was related to portly and stout. Shape 1 (31%) and Shape 2 (26%) were related to current big & tall category. Shape 3 (34%) were related to regular. Shape 4 (9%) were in portly and stout category. ASTM D 6240 standard was the only available standard that presented a regular fitting category. Various drops were found within a same chest size group; however, this study revealed great variances of drops by body shape.

Cloning of a Potentially Strain-Specific DNA Probe of prevotella intermedia ATCC 25611 by Inverted Dot Blot Hybridization Screening Method

  • Kook, Joong-Ki;Han, Jin-Ju;Kim, Hwa-Sook;Seong, Jin-Hyo;Kim, Dong-Kie;Baek, Dong-Heon;Choe, Son-Jin
    • Journal of Microbiology and Biotechnology
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    • v.13 no.2
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    • pp.282-286
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    • 2003
  • The purpose of this study was to isolate a specific DNA probe for the strain ATTC 25611 of the species Prevotella intermedia by using a new rapid screening mothod. The whole-genomic DNA of P. intermedia ATCC 25611 was isolated and purified. The HindIII-digested genomic DNAs from the strain were cloned by the random cloning method. To screen the strain-specific DNA probe, inverted dot blot hybridization tests were performed. In this assay, 20 ng of recombinant plasmids containing the HindIII-digested genomic DNA fragment were boiled and blotted onto a nylon membrane, and hybridized with digoxigenin-dUTP labeled genomic DNAs in a concentration of 100 ng/ml. Southern blot analysis was performed in order to confirm the results of the inverted dot blot hybridization tests. The data showed that a Pi34 probe (2.1 kbp; 1 out of 32 probes) was specific for P. intermedia strain ATCC 25611 and could be useful for the detection and identification of the strain, particularly in epidemiological studies of periodontal disease.

Selection of An Initial Training Set for Active Learning Using Cluster-Based Sampling (능동적 학습을 위한 군집기반 초기훈련집합 선정)

  • 강재호;류광렬;권혁철
    • Journal of KIISE:Software and Applications
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    • v.31 no.7
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    • pp.859-868
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    • 2004
  • We propose a method of selecting initial training examples for active learning so that it can reach high accuracy faster with fewer further queries. Our method is based on the assumption that an active learner can reach higher performance when given an initial training set consisting of diverse and typical examples rather than similar and special ones. To obtain a good initial training set, we first cluster examples by using k-means clustering algorithm to find groups of similar examples. Then, a representative example, which is the closest example to the cluster's centroid, is selected from each cluster. After these representative examples are labeled by querying to the user for their categories, they can be used as initial training examples. We also suggest a method of using the centroids as initial training examples by labeling them with categories of corresponding representative examples. Experiments with various text data sets have shown that the active learner starting from the initial training set selected by our method reaches higher accuracy faster than that starting from randomly generated initial training set.

Effects of Black Raspberry Wine on Testosterone Level of New Zealand White Rabbits (복분자 술이 가토의 testosterone에 미치는 영향 연구)

  • Lim, Chae-Woong;Jung, Mae-Myeong;Choi, Min-Jun;Lee, Sung-Il;Lee, Hee-Kwon;Jeon, Byung-Hun;Baek, Byeong-Kirl
    • Journal of Physiology & Pathology in Korean Medicine
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    • v.19 no.2
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    • pp.375-379
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    • 2005
  • This study was conducted to investigate the effects of black raspberry wine, administered per os on testosterone levels in rabbits. Black raspberry wine containing 13% alcohol(v/v) was prepared from ripe fruits of Rubus coreanus fermented with Saccharomyces cervisiae. Experimental rats were divided into 2 groups(A and B) with 2 animals group: Group A received black raspberry wine. Group B received 13% concentrated alcohol('Soju') over a period of 6 weeks. all animals were monitored weekly for testosterone levels by radioimmunoassay using $^{125}I$ labeled anti-testosterone monospecific antibody. There was a significant(1.7-2.33 fold) increase in testosterone levels in Group A with a peak at 1 week post administration of black raspberry wine. There was no significant change in testosterone levels of rabbits in Group B. These data point to yet uncharacterized phytotestronegenic mechanisms of black raspberry wine that appear to be independent of ethyl alcohol. Further investigation of the mechanism of action of this fruit is warranted. These observations have potential implications for human reproductive health.

Associations between dietary patterns and screen time among Korean adolescents

  • Lee, Jae Yeon;Jun, Nuri;Baik, Inkyung
    • Nutrition Research and Practice
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    • v.7 no.4
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    • pp.330-335
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    • 2013
  • Data are limited on the association between dietary patterns and screen time among Korean adolescents. The present study identified dietary patterns of 691 adolescents, aged 13-18 years, who had participated in the Third Korean National Health and Nutrition Examination Survey (KNHANES III) and analyzed their associations with screen time. Screen time was defined as the time spent watching TV, using a computer, or playing video games was calculated as a sum of all these times. Dietary patterns and their factor scores were derived from a food frequency questionnaire using the factor analysis method. To analyze the association between dietary patterns and screen time, we conducted multiple linear regression analysis. We also performed multiple logistic regression analysis to estimate odds ratios (OR) of excessive screen time (2 hours or longer per day) and 95% confidence intervals (CI). We identified 2 dietary patterns labeled "the Korean healthy dietary pattern" and "the Western diet and fast foods pattern". The former included mixed grains, legumes, potatoes, red meat, eggs, fish, dairy products, fruits, vegetables, seaweeds, and mushrooms, whereas the latter included noodles, bread, red meat, poultry, fast foods, snack, and soft drinks. After controlling for potential confounding factors, factor scores for the Korean healthy dietary pattern were inversely associated (P-value for trend < 0.01) and those for the Western diet and fast foods pattern were positively associated with the screen time (P-value for trend < 0.01). Adolescents in the top tertile of the scores for the Korean healthy dietary pattern had a multivariable-adjusted OR [95% CI] of 0.44 (0.25-0.75) for excessive screen time compared with those in the lowest tertile. On the basis of these findings, adolescents who have excessive screen time may need to be encouraged to consume a more healthy diet.