• Title/Summary/Keyword: Lab-on-a-chip

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Optical properties of ink color filters (잉크 색상 필터의 광학적 특성)

  • Lee, Chan-Ku;Lee, Su-Dae
    • Journal of Korean Ophthalmic Optics Society
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    • v.8 no.1
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    • pp.23-28
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    • 2003
  • We report a switchable RGB color filters for Lab on a chip. Ink color filter devices are fabricated by PDMS patterning process. The optical transmission in the ultra-violet and visible wavelengths of color filters have been investigated. The ink color filters are characterised by the slope and shape of the spectrum. The transmission of red/yellow filter consists of curves with a sharp cut-off spectrum at 600 and 500 nm. The blue output of the ink filter has 80% peak transmission and weak red-leak, while the green ink filter has 48% peak transmission and red-leak.

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Flow Analysis and Design of a Microchannel in a Lab-on-a-chip actuated with an Air Bladder (공기주입기로 구동되는 랩온어칩 내의 유동 해석과 미세 유로 설계)

  • Kang, Tae-Ho;Park, Sin-Wook;Yang, Sang-Sik
    • Proceedings of the KIEE Conference
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    • 2007.07a
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    • pp.1546-1547
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    • 2007
  • 휴대용 면역진단 시스템을 구현하기 위하여 설계된 공기주입기로 구동되는 랩온어칩 내의 유체 유동을 컴퓨터 시뮬레이션을 통하여 해석하고, 문제점을 보완할 수 있는 구조로 랩온어칩을 재설계하였다. 공기주입기에서 흘러나오는 공기를 이용해 완충액 저장고 내에 있는 완충액을 토출시킬 때 다량의 기포가 발생함을 시뮬레이션 결과를 통해 알 수 있었다. 완충액 저장고의 내부에 계단형 구조를 삽입함으로서 완충액 이송 시 형성되는 기포를 상당히 억제할 수 있었다. 또한 계단형 구조는 유선을 역행 방지판 쪽으로 분산시켜 역행 방지판의 효율을 높일 것이다.

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Design of A High-Speed Data Transmission System for Satellite Ground Inspection Trial

  • Hao Sun;Dae-Ki Kang
    • International journal of advanced smart convergence
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    • v.12 no.4
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    • pp.26-34
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    • 2023
  • A high-speed data transmission system is designed for the ground inspection equipment of satellite measurement and control. Based on USB2.0, the system consists of interface chip CY7C68013A, programmable logic processing unit EP4CE30F23C8, analog/digital and digital/analog conversion units. The working principle of data transmission is analyzed, and the system software logic and hardware composition scheme are detailed. The system was utilized to output/capture and store specific data packets. The results show that the high-speed data transmission speed can reach 38MB/s, and the system is effective for satellite test requirements.

Application of OLED as the Integrated Light source for the Portable Lab-On-a-Chip (휴대형 랩온어칩을 위한 집적화 광원으로의 OLED 적용)

  • Kim, Ju-Hwan;Shin, Kyeong-Sik;Kim, Young-Min;Kim, Yong-Kook;Yang, Yeun-Kyeong;Kim, Tae-Song;Kang, Ji-Yoon;Kim, Sang-Sig;Ju, Byeong-Kwon
    • Proceedings of the Korean Institute of Electrical and Electronic Material Engineers Conference
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    • 2004.05a
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    • pp.193-197
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    • 2004
  • The organic light emitting diode (OLED) is proposed as the novel source in the microchip because it has ideal merits (various wavelengths, thin-film structure and overall emitting) for the integration. In this paper, we fabricated the finger-type pin photodiodes for fluorescence detection and the advanced microchip with OLED integrated pn the microchannel. The finger-type in the diode design extended the depletion region and reduced the internal resistance about 31.2% than rectangular-type. The photodiodes had a 100pA leakage current and a 8720 sensitivity $(I_{Light}/I_{Dark})$ at -1 V bias. The interference filter with 32 layers ($SiO_2$, $TiO_2$) was directly deposited on the photodiode. The OLED was fabricated on the ITO coated glass and was bonded with LOC. The application of thin-film OLED increased the excitation efficiency and simplified the integration process extremely. The prototype device of this application had a superior sensitivity of 100nM-LOD in the fluorescence detection.

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Interdigitated Microelectrode Lab-on-a-chip sensing system for Biomoelcule Detection (마이크로패턴된 전극을 이용한 실시간 생체물질 감지 랩칩 시스템)

  • Yoo, Yong Kyoung;Hwang, Kyo Seon;Lee, Jeong Hoon
    • Proceedings of the KIEE Conference
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    • 2015.07a
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    • pp.1223-1224
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    • 2015
  • Recently, Alzheimer's Disease (AD) is one of the biggest threats to healthy society. Current medical AD diagnosis depends on interviews and the molecular neuroimaging. There is no cure for the disease, which worsens as it progresses, and eventually leads to death. Amyloid ${\beta}$ and Tau-meditated neuronal injury and dysfunction are candidates of biomarker for AD diagnosis using blood. For highly sensitive and selective biosensor platform, interdigitated microelectrodes (IMEs) sensor was prepared with micro fabrication process and Amyloid ${\beta}$ antibody. Amyloid ${\beta}$ concentration of 1, 10, 100, and 1000 pg/mL was injected in reaction chamber with IME sensors, impedance and conductance of IMEs changed respectively. These results show our newly proposed IMEs sensor can be usefully utilized for AD early diagnosis.

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Application of Bio-MEMS Technology on Medicine and Biology (Bio-MEMS : MEMS 기술의 의료 및 생물학 응용)

  • Jang, Jun-Geun;Jung, Seok;Han, Dong-Chul
    • Journal of the Korean Society for Precision Engineering
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    • v.17 no.7
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    • pp.45-51
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    • 2000
  • 지난 세기부터 MEMS 제작 기술을 이용하여 만들어진 시스템들을 의학이나 생물학적인 용도로 응용하기 위한 많은 연구가 활발히 이루어져 왔다. 기술적인 측면에서 이러한 연구들은 MEMS 분야의 초창기에 강조되어 온 표면 및 몸체 미세 가공 기술(surface & bulk micromachining)과 같은 미세 구조물 제작 기술의 발전에 힘입은 바 크다. 그러나 MEMS 기술이 점차 발전되어 오면서, 가공 기술이 고도화되고 미세 시스템의 구조가 점차 복잡해짐에 따라, 많은 연구들이 단순한 가공기술을 넘어 미세 시스템을 조립하고 집적화할 수 있는 기술, 접합 (bonding) 기술, 패키징 (packaging) 기술, 3차원 형상의 제작 기술, 실리콘(silicon)이나 유리(glass)가 아닌 다른 재료를 이용한 미세 가공 기술 등의 개발을 중심으로 이루어지고 있다.(중략)

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Integratable Micro-Doherty Transmitter

  • Lee, Jae-Ho;Kim, Do-Hyung;Burm, Jin-Wook;Park, Jin-Soo
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.6 no.4
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    • pp.275-280
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    • 2006
  • We propose Doherty power amplifier structure which can be integrated in Silicon RF ICs. Doherty power amplifiers are widely used in RF transmitters, because of their high Power Added Efficiency (PAE) and good linearity. In this paper, it is proposed that a method to replace the quarter wavelength coupler with IQ up-conversion mixers to achieve 90 degree phase shift, which allows on-chip Doherty amplifier. This idea is implemented and manufactured in CMOS 5 GHz band direct-conversion RF transmitter. We measured a 3dB improvement output RF power and linearity.

Permeability of the Lateral Air Flow through Unstructured Pillar-like Nanostructures (비정형 기둥 형상을 가진 나노구조에서의 가스 투과성 실험 연구)

  • Hyewon Kim;Hyewon Lim;Jeong Woo Park;Sangmin Lee;Hyungmo Kim
    • Tribology and Lubricants
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    • v.39 no.5
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    • pp.197-202
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    • 2023
  • Recently, research on experimental and analytical techniques utilizing microfluidic devices has been pursued. For example, lab-on-a-chip devices that integrate micro-devices onto a single chip for processing small sample quantities have gained significant attention. However, during sample preparation, unnecessary gases can be introduced into the internal channels, thus, impeding device flow and compromising specific function efficiency, including that of analysis and separation. Several methods have been proposed to mitigate this issue, however, many involve cumbersome procedures or suffer from complexities owing to intricate structures. Recently, some approaches have been introduced that utilize hydrophobic device structures to remove gases within channels. In such cases, the permeability of gases passing through the structure becomes a crucial performance factor. In this study, a method involving the deposition and sintering of diluted Ag-ink onto a silicon wafer surface is presented. This is followed by unstructured nano-pattern creation using a Metal Assisted Chemical Etching (MACE) process, which yields a nanostructured surface with unstructured pillar shapes. Subsequently, gas permeability in the spaces formed by these surface structures is investigated. This is achieved by experiments conducted to incorporate a pressure chamber and measure gas permeability. Trends are subsequently analyzed by comparing the results with existing theories. Finally, it can be confirmed that the significance of this study primarily lies in its capability to effectively evaluate gas permeability through unstructured pillar-like nanostructures, thus, providing quantitative values for the appropriate driving pressure and expected gas removal time in practical device operation.

Fabrication and Characteristics of Thermopneumatic-Actuated Polydimethylsiloxane microfluidic systems (Lab-on-a-chip과 m-TAS를 위한 미세 유체 시스템)

  • Moon, Min-Chul;Kim, Ju-Ho;Kim, Jin-Ho;Kang, C.J.;Kim, Yong-Sang
    • Proceedings of the KIEE Conference
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    • 2004.07c
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    • pp.2099-2101
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    • 2004
  • 본 연구에서 제안하는 마이크로 시스템은 열공압 방식으로 구동되고 제작비용이 저렴한 indium tin oxide (ITO) 및 polydimethylsiloxane (PDMS)로 제작되었다. 제안된 마이크로 밸브와 마이크로 펌프의 구조는 ITO 히터, SU-8 층, PDMS membrane, 그리고 PDMS 채널로 구성 되어 있다. 제안된 마이크로 펌프와 마이크로 밸브는 제작 공정 및 구조가 간단하고 값이 저렴하며, 마이크로 펌프와 마이크로 밸브를 같은 기판 위에 쉽게 직접화할 수 있는 장점을 가진다. 마이크로 밸브의 유량은 채널 폭에 비례하며 밸브가 closing 되는 전력은 채널의 폭과 상관없이 100 mW이다. 마이크로밸브의 ITO 히터의 온-오프에 따라 유량이 매우 잘 제어되었다. 제안된 마이크로 펌프의 경우, 히터의 인가 펄스 전압이 증가함에 따라 유량은 선형적으로 비례 증가함을 관찰할 수 있다. 마이크로 펌프의 최대 유량은 펄스 전압과 duty 비가 55V와 10%일 때 6 Hz에서 78 nl/min이 측정 되었다.

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Developement of IC Mark Checking System for IC Inspection Automation (반도체 소자(IC)의 검사 자동화를 위한 IC 표면의 마크 검사시스템 개발)

  • Bien, Zeung-Nam;You, Bum-Jae;Han, Dong-Il;Oh, Sang-Rok;Kim, Jung-Duck;Ha, Kyung-Ho
    • Proceedings of the KIEE Conference
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    • 1990.07a
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    • pp.471-474
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    • 1990
  • In this paper, a vision-based inspection algorithm for checking mark quality on an integrated chip(IC) is proposed. In order to reduce the processing time for inspection, we are implemented image arithmetic unit and binary image projection processor in hardware. By adopting the hardwares, the processing time becomes less one sixth of that in case of using software only.

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