• 제목/요약/키워드: La addition

검색결과 558건 처리시간 0.03초

Soybean Peptides Induce Apoptosis in HeLa Cells by Increasing Oxidative Stress

  • Sung, Ho Joong;Jeong, Yu Jin;Kim, Jihyun;Jung, Eunsun;Jun, Jin Hyun
    • 대한의생명과학회지
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    • 제21권2호
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    • pp.77-83
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    • 2015
  • Soy proteins have been extensively studied because of its multiple health benefits. However, the effects of soy proteins on human cervical cancer cells are still unclear. Therefore, this study investigated the effects of soy proteins on HeLa cells and human fibroblasts by using soybean peptides (SPs). SPs selectively increased the generation of reactive oxygen species and apoptosis in HeLa cells but not in fibroblasts. In addition, SPs suppressed the migration of HeLa cells. Although the molecular mechanisms underlying the effects of SPs on human cervical cancer cells need to be investigated further, our findings provide insights on the therapeutic effects of soy protein on cervical cancer.

압전응용을 위한 Langasite(La$_3$Ga$_5$SiO$_{14}$) 단결정의 성장 및 특성 (Growth and Characteristics of Langasite(La$_3$Ga$_5$SiO$_{14}$) Single Crystal for the Piezoelectric Applicatons)

  • 정일형;오근호
    • 한국세라믹학회지
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    • 제36권6호
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    • pp.640-645
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    • 1999
  • Recently rapid progress of electronic and telecommunication technology requires the development of new piezoelectric materials and cellular communication is more and more used in various fields. Langasite(La3Ga5SiO14) is suitable for new piezoelectric properties. Langastie can be applied as communication devices due to intermediate piezoelectric properties which are similar to those of quartz and LiTaO3 in its acoustic characteristics. So in this study Langastie(La3Ga5SiO14) single crystal with 47 mm in diameter and 25mm in length were sucessfully grown by using self-designed Czochralski system. In addition optimum growth conditions for the piezoelectric applications throughout estimation of crystal quality and frequency characteristics were investigated.

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SEARCH FOR DIETARY CONSTITUENTS WHICH PROTECT TOWARDS HETEROCYCLIC AROMATIC AMINES (HAs)

  • Knasmuller, Siegfried;Steinkellner, Hans;Zsivkovits, Markus;Uhl, Maria;Loste, Evelyn;Kassie, Fekadu
    • 한국독성학회:학술대회논문집
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    • 한국독성학회 2001년도 International Symposium on Dietary and Medicinal Antimutgens and Anticarcinogens
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    • pp.43-44
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    • 2001
  • The increasing evidence for the involvement of food borne HAs in the aetiology of human cancer has stimulated intense efforts to identify dietary constituents which protect against these compounds. About 280 articles on this topic have been published in the last 20 years, most of them were antimutagenicity studies with indicator cells that require addition of exogenous activation mix. The experimental models do not adequately reflect protective mechanisms that are active in vivo and may give misleading results.(omitted)

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Effects of the Addition of $La_2O_3$ on Mechanical Properties and Machinability of $Si_3N_4$ Ball

  • Sang Yang Lee;Sung Ho Kim;Soo Wohn Lee
    • The Korean Journal of Ceramics
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    • 제6권4호
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    • pp.364-369
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    • 2000
  • Silicon nitride with adding La$_2$O$_3$ was sintered by gas pressure sintering (GPS) technique at $1950^{\circ}C$, in $N_2$ gas at 3 MPa, for 2h. Mechanical properties such as hardness, flexural strength, and fracture toughness were determined as a function of the GPS holding time and the contents of La$_2$O$_3$ in silicon nitride. Also machinability of silicon nitride ball with various GPS holding time and amount of La$_2$O$_3$ was evaluated by magnetic fluid grinding (MFG) method. In this study it was found that machinability was influenced significantly with La$_2$O$_3$ contents. However, the different GPS holding time did not affect the machinability very much.

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메탄 부분산화반응 촉매에 La 첨가 및 제조방법에 따른 촉매활성에 미치는 영향 (Effects of La Addition and Preparation Methods on Catalytic Activities for Methane Partial Oxidation Catalysts)

  • 천한진;신기석;안성환;윤철훈;함현식
    • 한국가스학회지
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    • 제14권2호
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    • pp.7-14
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    • 2010
  • 메탄의 부분산화에 의하여 합성가스를 제조하였다. 저렴하며 본 반응에 활성이 좋은 것으로 알려진 Ni을 활성 물질로, 우수한 산소 저장능력과 높은 산화 환원 특성을 지닌 $CeO_2$를 담체로 하여, 함침법과 우레아법으로 촉매를 제조하였다. 반응은 고정층 반응기를 이용하여 1 atm, $650{\sim}800^{\circ}C$에서 실시하였다. 표면적 측정 장치를 이용하여 촉매 제조법에 따른 표면적 차이를 비교해 본 결과 우레아법으로 제조한 촉매가 함침법으로 제조한 촉매보다 표면적이 약 11배 이상 큼을 알 수 있었고, SEM으로 표면 구조를 조사해본 결과 우레아법으로 제조한 촉매가 훨씬 더 미세하고 균일함을 알 수 있었다. 우레아법으로 제조한 촉매가 함침법으로 제조한 촉매보다 더 높은 메탄 전환율 및 합성가스 선택도를 나타내었다. 본 반응의 문제점인 탄소 침적을 줄이기 위하여 La을 첨가하여 탄소 침적에 미치는 La의 영향을 알아보았다. TGA(열중량 분석기) 분석 결과 La이 첨가되지 않은 촉매에는 약 16%의 탄소 침적이, La을 첨가한 촉매에는 약 2%의 탄소 침적이 형성되었다. 따라서 La 첨가는 탄소 침적을 줄여서 촉매 비활성화를 막은 것으로 추정된다.

Growth Performance, Meat Quality and Fatty Acid Metabolism Response of Growing Meat Rabbits to Dietary Linoleic Acid

  • Li, R.G.;Wang, X.P.;Wang, C.Y.;Ma, M.W.;Li, F.C.
    • Asian-Australasian Journal of Animal Sciences
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    • 제25권8호
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    • pp.1169-1177
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    • 2012
  • An experiment was conducted to determine the effects of different amounts of dietary linoleic acid (LA) on growth performance, serum biochemical traits, meat quality, fatty acids composition of muscle and liver, acetyl-CoA carboxylase (ACC) and carnitine palmitoyl transferase 1 (CPT 1) mRNA expression in the liver of 9 wks old to 13 wks old growing meat rabbits. One hundred and fifty 9 wks old meat rabbits were allocated to individual cages and randomly divided into five groups. Animals in each group were fed with a diet with the following LA addition concentrations: 0, 3, 6, 9 and 12 g/kg diet (as-fed basis) and LA concentrations were 0.84, 1.21, 1.34, 1.61 and 1.80% in the diet, respectively. The results showed as follows: the dietary LA levels significantly affected muscle color of LL included $a^*$ and $b^*$ of experimental rabbits (p<0.05). The linear effect of LA on serum high density lipoprotein cholesterol was obtained (p = 0.0119). The saturated fatty acids (SFAs) and monounsaturated fatty acids (MUFAs) contents of LL decreased and the polyunsaturated fatty acids (PUFAs) content of LL increased with dietary LA increase (p<0.0001). The PUFA n-6 content and PUFA n-3 content in the LL was significantly affected by the dietary LA levels (p<0.01, p<0.05). The MUFAs content in the liver decreased and the PUFAs contents in the liver increased with dietary LA increase (p<0.0001). The PUFA n-6 content and the PUFA n-6/n-3 ratio in the liver increased and PUFA n-3 content in the liver decreased with dietary LA increase (p<0.01). The linear effect of LA on CPT 1 mRNA expression in the liver was obtained (p = 0.0081). In summary, dietary LA addition had significant effects on liver and muscle fatty acid composition (increased PUFAs) of 9 wks old to 13 wks old growing meat rabbits, but had little effects on growth performance, meat physical traits and mRNA expression of liver relative enzyme of experimental rabbits.

$0.96MgTiO_3-0.04SrTiO_3+xLa(0{\sim}1.0wt%)$ 세라믹스의 마이크로파 유전 특성 (The Microwave Dielectric Properties of $0.96MgTiO_3-0.04SrTiO_3+xLa(0{\sim}1.0wt%)$ Ceramics)

  • 박보근;임성수;김강;이영희
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 2001년도 추계학술대회 논문집 전기물성,응용부문
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    • pp.118-120
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    • 2001
  • The $0.96MgTiO_3-0.04SrTiO_3+xLa(0{\sim}1.0wt%)$ ceramics were prepared by conventional mixed oxide method. The structural properties of $0.96MgTiO_3-0.04SrTiO_3+xLa(0{\sim}1.0wt%)$ ceramics with sintering temperature were investigated by the XRD and SEM. From the X-ray diffraction patterns, it was found that the perovskite $SrTiO_3$ and ilmenite $MgTiO_3$ structures were coexisted in the $0.96MgTiO_3-0.04SrTiO_3$ ceramics. The second phase of $Sr_{0.5}LaTi_2O_6$ was shown with addition of the $La_2O_3$. The dielectric constant(${\varepsilon}_r$), $Q{\times}f$ value and the temperature coefficient of the $0.96MgTiO_3-0.04SrTiO_3+0.2La$ ceramics were 21. 41, 39991, $-3.3ppm/^{\circ}C$, respectively.

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$Ce_{0.8}Gd_{0.2}O_{1.9}$ 전해질에서 $La_{0.5}Sr_{0.5}MnO_{3-\delta}$ 양극의 과전압특성 (Cathodic Polarization of $La_{0.5}Sr_{0.5}MnO_{3-\delta}$ on $Ce_{0.8}Gd_{0.2}O_{1.9}$ Electrolyte)

  • 윤희성;노의범;김병호
    • 한국세라믹학회지
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    • 제35권9호
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    • pp.981-987
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    • 1998
  • $La_{0.5}Sr_{0.5}MnO_{3-\delta}$ as air electrode for soild oxide fuel cell was synthesized by a citrate process and its cathodic polarization was determinated by the current interruption method on the Gd-doped ceria as electrolyte. The addition of citric acid increased the exothermic heat for the formation of $La_{0.5}Sr_{0.5}MnO_{3-\delta}$ perovskite oxide. The degree of the initial particle agglomeration was affected by the exothermic heat. Also the increase of cal-cination temperature enlarged the particle size and the higher sintering temperature accelerated the den-sification of $La_{0.5}Sr_{0.5}MnO_{3-\delta}$ layer after its being painted on $Ce_{0.8}Gd_{0.2}O_{1.9}$ electrolyte. In this study $La_{0.5}Sr_{0.5}MnO_{3-\delta}$ synthesized by citrate process of which the molar ratio of citric acid to metal nitrate was 2 calcined at $650^{\circ}C$ for 2hr and sintered at 1100 at $1200^{\circ}C$ for 4 hrs after slurry coating on Ce0.8Gd0.2O1.9 electrlyte showed the lowest cathodic polarization.

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$La_{2}O_{3}$ 치환된 PMN계 세라믹스의 유전 및 전기적특성에 관한 연구 (A study on Dielectric and Electrical Properties using PMN Ceramics with $La_{2}O_{3}$ substitution)

  • 지승한;김병수;이능헌;이희규;김용혁;이덕출
    • 대한전기학회:학술대회논문집
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    • 대한전기학회 1996년도 하계학술대회 논문집 C
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    • pp.1621-1623
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    • 1996
  • The dielectric and polarizable properties of 0.85Pb$Mg_{1/3}Nb_{2/3}$)$O_3$-$0.125PbTiO_3$-$0.25BaTiO_3$ Ceramics have been investigated as a addition of the amount of $La_{2}O_{3}$($0{\leq}x{\geq}0.05$). The Temperature-dependant electrostictive characteristics of 0.85PMN-0.125PT-0.25BT relaxor ferroelectic system were improved by enhencing the extent of the diffuse phase transition(DPT). This was achieved using PMN-PT-BTceramics by the partial substitution of La at the Pb site. The curie temperature and the maximum dielectic permittivity decreased by substituting $La_{2}O_{3}$ and the electic field-related hysteresis phenomena decreased with increasing $La_{2}O_{3}$ substitution amount. It is showed decreasing in induced strain for electric field with increasing $La_{2}O_{3}$ substitution.

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