• 제목/요약/키워드: LTP

검색결과 124건 처리시간 0.025초

Long-Term Potentiation of Excitatory Synaptic Strength in Spinothalamic Tract Neurons of the Rat Spinal Cord

  • Hur, Sung Won;Park, Joo Min
    • The Korean Journal of Physiology and Pharmacology
    • /
    • 제17권6호
    • /
    • pp.553-558
    • /
    • 2013
  • Spinal dorsal horn nociceptive neurons have been shown to undergo long-term synaptic plasticity, including long-term potentiation (LTP) and long-term depression (LTD). Here, we focused on the spinothalamic tract (STT) neurons that are the main nociceptive neurons projecting from the spinal cord to the thalamus. Optical technique using fluorescent dye has made it possible to identify the STT neurons in the spinal cord. Evoked fast mono-synaptic, excitatory postsynaptic currents (eEPSCs) were measured in the STT neurons. Time-based tetanic stimulation (TBS) was employed to induce long-term potentiation (LTP) in the STT neurons. Coincident stimulation of both pre- and postsynaptic neurons using TBS showed immediate and persistent increase in AMPA receptor-mediated EPSCs. LTP can also be induced by postsynaptic spiking together with pharmacological stimulation using chemical NMDA. TBS-induced LTP observed in STT neurons was blocked by internal BAPTA, or $Ni^{2+}$, a T-type VOCC blocker. However, LTP was intact in the presence of L-type VOCC blocker. These results suggest that long-term plastic change of STT neurons requires NMDA receptor activation and postsynaptic calcium but is differentially sensitive to T-type VOCCs.

LTP 퍼니스의 내부 유동 및 온도 균일도 최적화를 위한 실천공학교육적 문제해결 (Problem Solving about Practical Engineering Education based on Analysis on Optimized Internal Flow of LTP Furnace and Uniformity of Temperature)

  • 김진우;윤기만;조은정
    • 실천공학교육논문지
    • /
    • 제10권2호
    • /
    • pp.125-129
    • /
    • 2018
  • 이 논문은 LTP 퍼니스의 최적화 된 내부 유동과 온도의 균일성에 대한 수치 해석에 관한 것이다. 반도체 제조 공정에서 실리콘 웨이퍼를 어닐링하기 위한 기능을 수행한다. 특히 챔버 내부의 최고 온도를 약 $400^{\circ}C$의 고온으로 유지하여 웨이퍼를 보강한다. 공정이 고온에서 완료되면 열 교환기를 통해 온도를 낮추고 이를 수행하기 위한 작업이 반복된다. 이 논문에서 최종적인 목표는 LTPS 퍼니스의 유동 해석을 통해 챔버의 단열 공급과 배기 구조의 최적 설계를 도출하는 것과 교육과정 개발을 위한 사례 발굴에 있다.

디지틀 이동통신용 RPE-LTP 음성부호화기

  • 김선영;김진업;정종태;김영식
    • 전자통신동향분석
    • /
    • 제5권4호
    • /
    • pp.42-59
    • /
    • 1990
  • 세계적인 추세에 근거하여, 디지틀 이동 통신용 음성 부호화 방식 표준안 선정을 위해 평가 대상 방식으로 DSBC(Dynamic bit allocation SubBand Coding), RPE-LTP(Regular Pulse Excited Long Term Prediction),CELP(Code Excited Linear Prediction) 등을 선정한 바 있다.본 논문에서는 이들 방식중 13 kbps RPE-LTP의 실현 및 성능평가에 관하여 다루었다. 먼저 음질에 중요한 영향을 미치는 분석/합성부호화에 근거한 파라미터 양자화 방법 그리고 채널 코딩과의 연계를 위한 비트 중요도 해석 등을 언급하였다. 끝으로 시뮬레이션 결과를 나타내었다.

기계시각을 이용한 잡초 식별 (Weed Identification Using Machine Vision)

  • 조성인;이대성;배영민
    • Journal of Biosystems Engineering
    • /
    • 제24권1호
    • /
    • pp.59-66
    • /
    • 1999
  • Weed identification is important for precision farming. A machine vision system was applied to detect weeds. Shape features were analyzed with the binary images obtained from color images of radish, purslane, goosefoot, and crabgrass. Features studied were aspect, roundness, compactness, elongation, PTB, LTP, LTW, and PTAL of each plant. Discriminant analysis was used to classify plant species. The best shape features that distinguished crabgrass were LTP and LTW which distinguished the crabgrass from the others with 100%. Two dimensional discrimination by using LTP and PTB appeared to be effective for distinguishing radish, purslane, and goosefoot.

  • PDF

TRACE PROPERTIES AND INTEGRAL DOMAINS, III

  • Lucas, Thomas G.;Mimouni, Abdeslam
    • 대한수학회보
    • /
    • 제59권2호
    • /
    • pp.419-429
    • /
    • 2022
  • An integral domain R is an RTP domain (or has the radical trace property) (resp. an LTP domain) if I(R : I) is a radical ideal for each nonzero noninvertible ideal I (resp. I(R : I)RP = PRP for each minimal prime P of I(R : I)). Clearly each RTP domain is an LTP domain, but whether the two are equivalent is open except in certain special cases. In this paper, we study the descent of these notions from particular overrings of R to R itself.

A Study of the Oxygen Plasma Treatment on the Serviceability of a Wool Fabric

  • Kan, C.W.;Chan, K.;Yuen, C.W.M.
    • Fibers and Polymers
    • /
    • 제5권3호
    • /
    • pp.213-218
    • /
    • 2004
  • Low temperature plasma (LTP) treatment using oxygen gas was applied to a wool fabric. The LTP treated wool fabric was tested with several methods: ASTM D5035-1995, ASTM D1424-1996, AATCC Test Method 99-2000, AATCC Test Method 61-2001 lA, AATCC Test Method 15-2002 and AATCC Test Method 8-2001 and the results were compared with the industrial requirements (ASTM D3780-02 and ASTM D4155-0l). The results revealed that the LTP treated wool fabric could fulfil the industrial requirements. The results of the investigation were discussed thoroughly in this paper.

DCCA 처리와 저온플라즈마 처리가 양모직물의 염색성에 미치는 영향 (Effect of Low Temperature Plasma and DCCA treatment on the Dyeing Properties of Wool Fabric)

  • 정영진
    • 한국염색가공학회지
    • /
    • 제20권4호
    • /
    • pp.53-59
    • /
    • 2008
  • For the modification of wool surface, wool fabrics treated with oxygen low-temperature plasma(LTP) and dichloroisocyanuric acid(DCCA) were dyed with milling type acid dye. The difference of dyeing properties on modified and control wool fabric were investigated. DCCA treated wool showed that saturation dye uptake and dyeing desorption ratio were higher than LTP treated wool. Dyeing transition temperatures of DCCA and LTP treated wool fabrics were 20$^{\circ}C$ degree lower than control wool fabric. In light color fastness test, DCCA treated wool fabric was 1 grade lower than LTP or control wool fabric.

소비자의 시간압박 수준에 따른 패션정보원, 추구혜택, 구매기준 비교연구 (Comparison on Fashion Information Sources, Clothing Benefits Sought & Purchase Criteria according to Consumers' Time Pressure Level)

  • 김칠순;이진화
    • 한국의류학회지
    • /
    • 제30권1호
    • /
    • pp.20-30
    • /
    • 2006
  • The purposes of this study were to investigate demographic profiles between the consumer group under high time pressure(HTP) and the group under low time pressure(LTP) during the shopping, to examine the level of association between the fashion information sources and time pressure variable, to determine the difference in clothing benefits sought between HTP and LTP, and to determine the difference in purchase criteria. We distributed questionnaires to 600 women aged in 20-65. The reliable 562 questionnaires were used for a statistical analysis. Data analyses were conducted with SPSS program on t-test, cluster analysis, factor analysis, and Chi square test. We obtained the following results: There was a significant association between demographic variables such as age, occupation, education, residence area, & family cycle and time pressure variable. Fashion information sources were classified into 4 factors. HTP searched information on fashion products using more various sources than LTP did. There was also a significant difference between HTP and LTP in clothing benefit sought. Four clothing benefit factors such as trendy/social position, economic value, protection/comfort, and makeup of body shape were sought more by HTP than by LTP. In addition, HTP considered significantly more purchase criteria such as color/pattern, comfort, quality, suitability, material, sewing finishing, coordination, price, brand, easy care, and country of origin than LTP.

급성 일산화탄소 중독 후 해마에서 Parvalbumin 양성 중간뉴론의 변화에 대한 N-acetylcystein의 효과 (Effects of N-acetylcystein on changes in parvalbumin-positive interneurons in the hippocampus after carbon monoxide poisoning)

  • 김선태;유수진
    • 대한임상독성학회지
    • /
    • 제19권2호
    • /
    • pp.100-109
    • /
    • 2021
  • Purpose: The purpose of this study was to investigate effect of N-acetylcysteine (NAC) on the injury of putative parvalbumin positive interneurons defined by molecular marker and hippocampal long-term potentiation (LTP), a marker of neural plasticity following acute carbon monoxide (CO) poisoning. Methods: Adult Sprague-Dawley rats were exposed to 1100 ppm CO for 40 minutes followed by 3000 ppm CO for 20 minutes. Animals received daily intraperitoneal injection of NAC (150 mg/kg) for 5 days after CO exposure. Changes in learning and spatial memory were evaluated by Y-maze test 5 days after the poisoning. In vivo LTP in hippocampal CA1 area was evaluated by using extracellular electrophysiological technique. Immunohistochemical staining were adopted to observe expressional damages of parvalbumin (PV) immunoreactive interneurons in the hippocampus following the poisoning. Results: Acute CO intoxication resulted in no changes in memory performance at Y-maze test but a significant reduction of LTP in the in hippocampal CA1 area. There was also a significant reduction of PV (+) interneurons in the hippocampal CA1 area 5 days after CO poisoning. Daily treatment of NAC significantly improved hippocampal LTP impairment and reduced immunoreactivity for PV in the hippocampus following the acute CO poisoning. Conclusion: The results of this study suggest that reduction of hippocampal LTP and PV (+) interneurons in the hippocampus is sensitive indicator for brain injury and daily NAC injections can be the alternative therapeutics for the injury induced by acute CO poisoning.

Three-dimensional evaluation of the association between tongue position and upper airway morphology in adults: A cross-sectional study

  • Yuchen Zheng;Hussein Aljawad;Min-Seok Kim;Su-Hoon Choi;Min-Soo Kim;Min-Hee Oh;Jin-Hyoung Cho
    • 대한치과교정학회지
    • /
    • 제53권5호
    • /
    • pp.317-327
    • /
    • 2023
  • Objective: This study aimed to evaluate the association between low tongue position (LTP) and the volume and dimensions of the nasopharyngeal, retropalatal, retroglossal, and hypopharyngeal segments of the upper airway. Methods: A total of 194 subjects, including 91 males and 103 females were divided into a resting tongue position (RTP) group and a LTP group according to their tongue position. Subjects in the LTP group were divided into four subgroups (Q1, Q2, Q3, and Q4) according to the intraoral space volume. The 3D slicer software was used to measure the volume and minimum and average cross-sectional areas of each group. Airway differences between the RTP and LTP groups were analyzed to explore the association between tongue position and the upper airway. Results: No significant differences were found in the airway dimensions between the RTP and LTP groups. For both retropalatal and retroglossal segments, the volume and average cross-sectional area were significantly greater in the patients with extremely low tongue position. Regression analysis showed that the retroglossal airway dimensions were positively correlated with the intraoral space volume and negatively correlated with A point-nasion-B point and palatal plane to mandibular plane. Males generally had larger retroglossal and hypopharyngeal airways than females. Conclusions: Tongue position did not significantly influence upper airway volume or dimensions, except in the extremely LTP subgroup.