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The role of nitric oxide as an effector of macrophage-mediated cytotoxicity against Trichomonas vaginalis (질편모충에 대한 대식세포의 세포독성에 있어서 NO의 역할)

  • Park, Geon-Chae;Ryu, Jae-Suk;Min, Deuk-Yeong
    • Parasites, Hosts and Diseases
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    • v.35 no.3
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    • pp.189-196
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    • 1997
  • The purpose of this study is to determine whether nitric oxide is involved in the extracellular killing of Trichomoncs uasinalis by mouse (BALB/c) peritoneal macrophages and RAW264.7 cells activated with LPS or rIFN-γ and also to observe the effects of various chemicals which affect the production of reactive nitrogen intermediates (RNl) in the cytotoxicity against T. vnginnlis. The cytotoxicity was measured by counting the release of (3H)-thymidine from labelled protozoa and NOa was assayed by Griess reaction. Nemonomethyl-L-arginine (L-NMHA), Nenitro-L-arginine methyl ester (NAME) and arginase inhibited cytotoxicity to T. vaginnlis and nitrite production by activated mouse perioneal macrophagrs and RAW 264.7 cells. The addition of excess L-arginine competitively restored trichomonacidal activity of macrophages. Exogenous addition of FeSO4 inhibited cytotoxicity to T. vaginaLis and nitric products of macrophages. From above results, it is assumed that nitric oxide plays an important role in the host defense mechanism of macrophages against T ucfinalis.

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Redescription of Mocroorchis spinulosus Ando, 1918 (Digenea: Nanophyetidae) encysted in the fresh water crayfish, Cambcroides similis (참가재(Cambaroides similis)에 피낭한 가시큰고환흡충 (Marroorchis spinulosus Ando, 1918)의 재기록)

  • 채종일;손운목
    • Parasites, Hosts and Diseases
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    • v.34 no.1
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    • pp.1-6
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    • 1996
  • Mccroorchis spinuLosw Ando, 1918 (Digenea: Nanophyetidael is redescribed based on adult flukes recovered from experimental mice, rats and cats which were fed with metacercariae encysted in the muscle of the crayfish, Cambnroines similis. A total of 117 adult flukes were harvested from the small intestine of the experimental animals at S-21 days post-infection. The worm recovery rate was 31-37%, not significantly different among the three kinds of animals. The metacercariae were round, 0.18 mm in average diameter, encysted with two layers of thick walls, and possessing a stylets on the oral sucker and Y- shaped exc retory bladder. The adult flukes were oval, 0.66-0.71 mm long and 0.36-0.41 mm wide, and characterized by the presence of a stylet on the oral sucker, variable location of the ovary near the mid-portion of the body, bilobed seminal vesicle, and anterolateral location of two testes. These morphological features were a little different from the original description, hence, an emended version of M. spinulosw was given. M. spinuLosw is a new intestinal trematode of animals and possibly man in Korea.

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A Systematic Review on Concept-based Image Retrieval Research (체계적 분석 기법을 이용한 의미기반 이미지검색 분야 고찰에 관한 연구)

  • Chung, EunKyung
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.25 no.4
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    • pp.313-332
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    • 2014
  • With the increased creation, distribution, and use of image in context of the development of digital technologies and internet, research endeavors have accumulated drastically. As two dominant aspects of image retrieval have been considered content-based and concept-based image retrieval, concept-based image retrieval has been focused in the field of Library and Information Science. This study aims to systematically review the accumulated research of image retrieval from the perspective of LIS field. In order to achieve the purpose of this study, two data sets were prepared: a total of 282 image retrieval research papers from Web of Science, and a total of 35 image retrieval research from DBpia in Kore for comparison. For data analysis, systematic review methodology was utilized with bibliographic analysis of individual research papers in the data sets. The findings of this study demonstrated that two sub-areas, image indexing and description and image needs and image behavior, were dominant. Among these sub-areas, the results indicated that there were emerging areas such as collective indexing, image retrieval in terms of multi-language and multi-culture environments, and affective indexing and use. For the user-centered image retrieval research, college and graduate students were found prominent user groups for research while specific user groups such as medical/health related users, artists, and museum users were found considerably. With the comparison with the distribution of sub-areas of image retrieval research in Korea, considerable similarities were found. The findings of this study expect to guide research directions and agenda for future.

A Study on Legal Protection, Inspection and Delivery of the Copies of Health & Medical Data (보건의료정보의 법적 보호와 열람.교부)

  • Jeong, Yong-Yeub
    • The Korean Society of Law and Medicine
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    • v.13 no.1
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    • pp.359-395
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    • 2012
  • In a broad term, health and medical data means all patient information that has been generated or circulated in government health and medical policies, such as medical research and public health, and all sorts of health and medical fields as well as patients' personal data, referred as medical data (filled out as medical record forms) by medical institutions. The kinds of health and medical data in medical records are prescribed by Articles on required medical data and the terms of recordkeeping in the Enforcement Decree of the Medical Service Act. As EMR, OCS, LIS, telemedicine and u-health emerges, sharing and protecting digital health and medical data is at issue in these days. At medical institutions, health and medical data, such as medical records, is classified as "sensitive information" and thus is protected strictly. However, due to the circulative property of information, health and medical data can be public as well as being private. The legal grounds of health and medical data as such are based on the right to informational self-determination, which is one of the fundamental rights derived from the Constitution. In there, patients' rights to refuse the collection of information, to control recordkeeping (to demand access, correction or deletion) and to control using and sharing of information are rooted. In any processing of health and medical data, such as generating, recording, storing, using or disposing, privacy can be violated in many ways, including the leakage, forgery, falsification or abuse of information. That is why laws, such as the Medical Service Act and the Personal Data Protection Law, and the Guideline for Protection of Personal Data at Medical Institutions (by the Ministry of Health and Welfare) provide for technical, physical, administrative and legal safeguards on those who handle personal data (health and medical information-processing personnel and medical institutions). The Personal Data Protection Law provides for the collection, use and sharing of personal data, and the regulation thereon, the disposal of information, the means of receiving consent, and the regulation of processing of personal data. On the contrary, health and medical data can be inspected or delivered of the copies, based on the principle of restriction on fundamental rights prescribed by the Constitution. For instance, Article 21(Access to Record) of the Medical Service Act, and the Personal Data Protection Law prescribe self-disclosure, the release of information by family members or by laws, the exchange of medical data due to patient transfer, the secondary use of medical data, such as medical research, and the release of information and the release of information required by the Personal Data Protection Law.

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Genetic variance of Tuchomonns uaginclis isolates by Southern hybridization (Southern hybridization에 의한 질편모충의 유전학적 다양성)

  • 류재숙;민득영
    • Parasites, Hosts and Diseases
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    • v.36 no.3
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    • pp.207-212
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    • 1998
  • In the present study, genomic DNAs were purified from Korean isolates (KT8, KT6, KT-Kim and KT-Lee) and foreign strains (CDC85, IR78 and NYH 286) of 1Trichomonas voslnalis, and hybridized with a probe based on the repetitive sequence cloned from T. uqfinolis to observe the genetic differences. By Southern hybridization, all isolates of T. uoSinoLis except the NYH386 strain had 11 bands. Therefore all isolates examined were distinguishable into 3 groups according to their banding patterns; i) KT8, KT6 and KT-Kim isolates had 11 identical bands such as 1 kb, 1.2 kb, 1.6 kb, 1.9 kb, 2.3 kb. 27 kb, 3.2 kb, 2.4 kb, 3.8 kb, 4.9 kb and 6.0 kb, ii) The metronidazole-resistant IR78 strain had the some bands as KT-Lee isolate at bands of 1 kb, 1.2 kb, 1.6 kb. 1.8 kb, 2.1 kb, 2.5 kb, 2.7 kb, 2.9 kb, 3.4 kb, 5.0 kb and 6.0 kb, Bands of CDC85, metronidazole-resistant strain, were similar to those of IR78 and KT-Lee, except that 3.2 kb replaced 2.9 kb. iii) NYH286 particularly had 12 bands and bun patterns were similar to IR78 with a few exceptions as follows; i) 6.2 kb in place of 6.0 kb, ii) 2.0 kb and 2.2 kb instead of 2.1 kb. Through the results obtained, genetic variance of T. uoginnlis isolates was demonstrated by Southern hybridization.

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A Study on the Relationship Between Child Poverty Rate and Family Policy Expenditure of Welfare States -Focused on OECD Countries- (복지국가의 아동·가족복지지출과 아동빈곤율의 관계 -OECD 국가를 중심으로-)

  • Ryu, Yun Kyu;Baek, Seung Ho
    • Journal of the Korean Society of Child Welfare
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    • no.36
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    • pp.65-99
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    • 2011
  • The main purpose of this study is to analyze the relationship between child poverty rate and family policy expenditure of welfare states (focusing on OECD countries). We analyzed not only the total social & family policy expenditures but the components of the family policy expenditure. OECD SOCX and calculated data from the LIS & OECD data were utilized for child and family policy expenditures and the poverty rate. One-way correlation and cluster analysis were employed for the analysis. The analytic results are as follows: Southern European and Anglo-Saxon countries' child poverty rates were higher and Scandinavian countries' child poverty rates were lower than any other clusters. The countries with high child poverty rate had higher child poverty rate than the entire nation's poverty rate, but Scandinavian countries' child poverty rate was lower. There was a strong correlation between family policy expenditure and child poverty rate. Especially the service expenditure and leave benefit expenditure were highly correlated with child poverty rate. On the other hand, cash expenditure was not significantly correlated with child poverty rate. We can suggest the policy implications from these results. Based on the analytic results, policy implications that the government should increase the family policy budget, especially the budget for family services and leave benefit to decrease child poverty rate and should make effort to support the employment of parents through policies such as active labor market strategies can be suggested.

Study of germination for none seasonal pruning mulberry farm and their insective diseases (순상전 춘기말벌채고조의 발아상태와 충해 발생 관계)

  • 도경화
    • Journal of Sericultural and Entomological Science
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    • v.3
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    • pp.13-21
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    • 1963
  • 1. In the mulberry groves for both rearing of spring and fall, the rate of germination was 74.3 percent and the rate of the unfinished bud was 25.7 percent. 2. When the summer pruning after spring rearing was not worked, new sprouted leaves from the axillary buds of an age old branches was 74.88 percent of germination and the rest from unfinished bud during the spring showed 28.12 percent. 3. In the furrows running from north to south, new buds facing the due north were the worst but towards south-east and north-east were the best in their sprouts. 4. One year-old branches which had been raised without the summer pruning in the bush types of Morus Lhou (ser) Koidz offered a habitat where Apriona Rugico1lis Cherr could live. 5. On the grove of Morus Lhou Koidz cultivated at lower zone under a higher humidity and the shortage of sun light the appearance of Anomoneura Mori Schw was likely to happen very much. 6. One year old branches without the summer pruning produced more leaves owing to a long period of growth than branches with the summer pruning in the fall crops. 7. It is necessary to reconsider a certain distance of planting because of causing, when the summer pruning was not made in the bush plantation, a obstacle of fertilizer operation or the forth coming year's management. 8. It can not be thought the ideal method for us to raise mulberry tree such as Morus Lhou Koidz under natural form and at a short distance of planting (one another). 9. Among the species, Morus alba L. had a great deal of leaves and of the rate of germination per unit length of branch.

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Study on the Openness of International Academic Papers by Researchers in Library and Information Science Using POI (Practical Openness Index) (POI(Practical Openness Index)를 활용한 문헌정보학 연구자 국제학술논문의 개방성 연구)

  • Cho, Jane
    • Journal of Korean Library and Information Science Society
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    • v.52 no.2
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    • pp.25-44
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    • 2021
  • In a situation where OA papers are increasing, POI, which indexes how open the research activities of individual researchers are, is drawing attention. This study investigated the existence of OA papers and the OA method published in international academic journals by domestic LIS researchers, and derived the researchers' POI based on this. In addition, by examining the relationship between the POI index and the researcher's amount of research papers, the research sub field, and the foreign co-authors, it was analyzed whether these factors are relevant to the researcher's POI. As a result, there were 492 papers by 82 researchers whose OA status and method were normally identified through Unpaywall. Second, only 20.7% of papers published in international journals were open accessed, and almost cases were gold and green methods. Third, there were many papers in text mining in medical journals, and the papers opened in the green method are open in institutional repositories of foreign co-authors or transnational subject repositories such as PMC. Third, the POI index was relatively higher for researchers in the field of informetrics, machine learning than other fields. In addition, it was analyzed that the presence or absence of overseas co-authors is related to OA.

An Examination of Core Competencies for Data Librarians (데이터사서의 핵심 역량 분석 연구)

  • Park, Hyoungjoo
    • Journal of the Korean BIBLIA Society for library and Information Science
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    • v.33 no.1
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    • pp.301-319
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    • 2022
  • In recent decades, research became more data-intensive in the fast-paced information environment. Researchers are facing new challenges in managing their research data due to the increasing volume of data-driven research and the policies of major funding agencies. Information professionals have begun to offer various data support services such as training, instruction, data curation, data management planning and data visualization. However, the emerging field of data librarians, including specific roles and competencies, has not been clearly established even though librarians are taking on new roles in data services. Therefore, there is a need to identify a set of competencies for data librarians in this growing field. The purpose of this study is to consider varying core competencies for data librarians. This exploratory study examines 95 online recruiting advertisements regarding data librarians posted between 2017 and 2021. This study finds core competencies for data librarians that include skills in technology, communication and interpersonal relationships, training/consulting, service, library management, metadata knowledge and knowledge of data curation. Specific core technology skills include knowledge of statistical software and computer programming. This study contributes to an understanding of core competencies for data librarians to help future information professionals prepare their competencies as data librarians and the instructors who develop and revise curriculum and course materials.

Establishment of hydraulic/hydrological models in the Mekong pilot area using global satellite-based water resources data (focusing on HEC-RTS/HMS model application) (글로벌 위성기반 수자원 데이터 활용 메콩지역 수리/수문모델 시범 구축 (HEC-RTS/HMS 모형 적용을 중심으로))

  • Cho, Younghyun;Park, Sang Young;Park, Jin Hyeog
    • Proceedings of the Korea Water Resources Association Conference
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    • 2021.06a
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    • pp.111-111
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    • 2021
  • 메콩지역은 최근 연 7%에 육박하는 경제성장률을 달성하며 아세안의 고성장을 지속 견인하고 있으나, 기후변화 및 급속한 도시화로 매년 가뭄·홍수 등 물 관련 재해 발생 빈도 및 강도 증가와 이에 따른 상·하류 국가간 물 분쟁 등으로 인해 메콩지역 지속가능 발전에 지장이 초래되고 있다. 이에 한국과 미국은 메콩우호국(Friends of the Lower Mekong, FLM) "메콩지역 수자원 데이터 관리 및 정보공유 강화에 관한 공동성명(2018년 8월)"을 계기로 메콩유역의 실시간 수자원 변동 모니터링 및 분석과 수자원 데이터 공동활용 역량을 강화하여 효율적이고 과학적인 수자원관리 지원과 함께 한국의 신남방정책과 미국의 인도-태평양 전략 시너지효과를 극대화하고자 메콩 주변국 재해경감 및 수자원 데이터 활용 역량강화를 위한 글로벌 위성기반 수문자료의 생산·활용 및 홍수·가뭄 등의 수재해 분석기술을 개발하고 있다. 여기에는 한국 K-water의 물관리 기술과 미국 NASA, USACE의 위성활용 및 수자원분석 기술을 접목하여 메콩지역의 체계적인 물관리 및 재해로부터 안전성 확보 기여에 목표를 두고 연구를 진행 중에 있다. 본 연구에서는 전 세계적으로 광범위하게 활용되고 있는 미공병단(USACE, U.S. Army Corps of Engineers)의 HEC software 프로그램을 메콩 시범지역(pilot area)에 적용하여 수리/수문모델 구축을 진행코자 한다. 구축되는 모형은 유역 상류 댐의 연계 모의운영 및 하류 홍수분석이 동시 가능한 HEC-RTS(Real-Time Simulation)로 이는 HEC-HMS, -ResSim, -RAS와 -FIA 모형이 순차적으로 결합된 수리/수문 모델링 시스템이다. 모형의 시범적용 지역은 현지 메콩위원회(MRC, Mekong River Comission)의 의견 등을 반영, 메콩강 하류지역(Lower Mekong) 본류 유역에 위성 자료 활용 및 준실시간(near real-time)으로 댐 모의운영 등을 고려할 수 있는 JingHong댐(중국 란창강 최하류)에서 라오스 Xayaburi댐(메콩강 최상류)까지의 구간을 선정하였다. 한편, 금번 연구에서는 HEC-RTS 중 HMS 모형 적용을 중심으로 가용한 위성자료(GPM IMERG)와 K-LIS 지표 모형 생산 자료를 활용하여 과거 홍수사상에 대한 모의를 고려하였다. 아울러, 연구에서 구축된 HMS 모형은 HEC-RTS에 포함되어 메콩 시범지역의 종합적 수리/수문분석에 적용될 예정이다.

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