• Reproductive and Developmental Biology
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• 제37권3호
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• pp.103-108
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• 2013

An uterus is female reproductive tract organ that affected estrus cycle. During a various changes occur at uterus in estrus cycle, one of them is body fluids secretion be called uterine fluid. Therefore, the objective of this study was to investigate the changes of protein patterns using two-dimensional gel electrophoresis in uterus fluids during the follicular and luteal phases in estrus cycle of pigs. In changes of protein spots were confirmed during the follicular and luteal phases. The 136 spots were expressed in follicular phase, the 57 spots of them showed reproducibility. On the other hand, the 140 spots were expressed in luteal phase, the 73 spots of them showed reproducibility. Also, spots expressed in follicular phase were number 69 and 94 spots and spots expressed in luteal phase only were number 156, 157, 184~187, 190 and 191 spots. The spots which of higher expression levels in the luteal phase than in follicular phase were number 76 and 79 spots. In conclusion, the spots expressed in follicular and luteal phases were confirmed with difference levels and these differences are function of RNA resolving, protein synthesis and cytoskeletal architecture.

• 토지주택연구
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• 제6권4호
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• pp.165-175
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• 2015

본 연구는 정부의 효율적인 공기업 관리정책 추진을 위해서는 기본적으로 공기업의 수명주기 단계를 파악하고 이에 기초한 정책결정이 필요하다는데 연구의 초점을 갖고 있다. 이를 위해 공기업에 적용 가능한 기업수명주기 분류변수를 정의하고 공기업 관리정책의 기초자료로 제공하는데 연구의 목적을 갖고 있다. 이러한 연구목적의 달성을 위해 공기업 중 최근 급격한 부채 증가로 인해 공기업 경영정상화의 대표적인 대상 기업으로 선정된 한국도로공사, 한국수자원공사, 한국철도공사, 한국토지주택공사 등 준시장형 SOC 공기업을 연구범위로 선정하였다. 본 연구는 분류변수 간의 중요도와 적용기준 분석을 위해 1차 전문가 설문조사를 실시하였다. 이를 바탕으로 AHP분석과 빈도분석 등의 통계분석을 활용하여 준시장형 SOC 공기업의 수명주기 분류변수 간 중요도와 적용기준을 분석하였다. 또한, 쇠퇴기 판별을 통해 예상되는 쇠퇴기에서 관리방안을 살펴보고자 2차 전문가 설문조사를 실시하였고, 이들 공기업의 쇠퇴기 예상시기 및 쇠퇴기에서의 관리방법에 대하여 조사 분석하였다.

• 한국콘텐츠학회논문지
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• 제17권7호
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• pp.44-55
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• 2017

최근에 많은 기업들이 기업 목표를 달성하기 위해 프로세스 혁신이나 개선을 지속적으로 꾀하고 있으며, 이를 지원하는 도구로 BPM (Business Process Management)이 많이 도입되고 있다. BPM의 생애 주기는 프로세스 진단, (재)설계 및 실행으로 이루어지는데, 모든 BPM 활동들은 성과 척도와 밀접한 관련을 갖고 운영되어야 한다. 본 논문의 목적은 프로세스 기반 성과 측정 모델과 통합된 생애 주기 기반 BPM 프레임워크를 제안하는 것이다. 제안 프레임워크에서는 BPM 전 생애 주기 동안 비즈니스 프로세스와 성과 척도가 체계적인 상관관계를 가지고 밀접하게 운영된다. 기업의 혁신이나 개선 담당자들은 제안 프레임워크를 사용하여 프로세스 진단 단계에서는 기업 성과에 가장 영향을 주는 프로세스를 용이하게 확인할 수 있고, 프로세스 (재)설계 단계에서는 새롭게 설계된 프로세스의 성과를 측정할 수 있으며, 프로세스 실행 단계에서는 성과 척도를 모니터하여 비즈니스 활동 들을 조정할 수 있게 된다.

• Environmental Engineering Research
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• 제13권1호
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• pp.1-7
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• 2008

Recently a new technology called the flexible-fiber deep-bed filter (FDF) claimed to replace the conventional sand filter including coagulation and sedimentation filter (CSF) processes in the water treatment plant. Therefore the life cycle assessment (LCA) approach was applied for evaluating the life cycle impacts of FDF compared with those of CSF. The used LCA softwares were the Simapro 6 and PASS and their life cycle impact assessment (LCIA) methodologies were the Eco-indicator 99 and the Korean Eco-indicator, respectively. The goal of this LCA was to identify environmental loads of CSF and FDF from raw material to disposal stages. The scopes of the systems have been determined based on the experiences of existing CSF and FDF. The function was to remove suspended solids by filtration and the functional unit was $1\;m^3$/day. Both systems showed that most environmental impacts were occurred during the operation stage. To reduce the environmental impacts the coagulants and electricity consumptions need to be cut down. If the CSF was replaced with the FDF, the environmental impacts would be reduced in most of the impact categories. The LCA results of Korean Eco-indicator and Eco- indicator99 were quite different from each other due to the indwelling differences such as category indicators, impact categories, characterization factors, normalization values and weighting factors. This study showed that the life cycle assessment could be a valuable tool for evaluating the environmental impact of the new technology which was introduced in water treatment process.

• 한국도로학회논문집
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• 제17권2호
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• pp.143-150
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• 2015

PURPOSES : The authors set out to estimate the related carbon emissions, energy use, and costs of the national freeways and highways in Korea. To achieve this goal, a macro-level methodology for estimating those amounts by road type, road structure type, and road life cycle was developed. METHODS : The carbon emissions, energy use, and costs associated with roads vary according to the road type, road structure type, and road life cycle. Therefore, in this study, the road type, road structure type, and road life cycle were classified into two or three categories based on criteria determined by the authors. The unit amounts of carbon emissions and energy use per unit road length by classification were estimated using data gathered from actual road samples. The unit amounts of cost per unit road length by classification were acquired from the standard cost values provided in the 2013 road business manual. The total carbon emissions, energy use, and cost of the national freeways and highways were calculated by multiplying the road length by the corresponding unit amounts. RESULTS: The total carbon emissions, energy use, and costs associated with the national freeways and highways in Korea were estimated by applying the estimated unit amounts and the developed method. CONCLUSIONS: The developed method can be employed in the road planning and design stage when decision makers need to consider the impact of road construction from an environmental and economic point of view.

• 한국강구조학회 논문집
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• 제18권6호
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• pp.677-686
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• 2006

본 논문에서는 생애주기비용뿐만 아니라 생애주기성능 조건을 함께 고려하여 열화되는 교량의 최적 유지관리 전략 수립을 위한 보다 실제적이고 현실적인 방법을 제안하였다. 교량의 성능 및 비용과 관련된 다중목적 조합 최적화 문제인 교량 유지관리 시나리오 집합의 생성을 위해 유전자 알고리즘을 적용하였으며, 다중목적함수에 대한 최적의 균형 잡힌 유지관리 시나리오의 선정이 가능한 기법을 제안하였다. 최적 유지관리 시나리오는 부재수준뿐만 아니라 교량 시스템 수준에서도 생성 가능하도록 하였다. 실제 공용중인 교량에 적용하여 제안된 방법의 실 적용성을 검증하고 분석하였다. 제안된 방법은 기존의 유지관리방법의 한계를 극복하고, 실질적인 예방유지관리체계의 도입을 위한 교량 유지관리 의사결정에 활용될 수 있을 것으로 기대된다.

• 상하수도학회지
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• 제25권6호
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• pp.885-892
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• 2011

In this study, LCA(Life Cycle Assessment) on 'Saemangum CSO Project' was carried out to evaluate environmental impact which occurred during the construction and operation periods and the potential environmental impact reduction was analyzed by comparing production and reduction level of pollution loads. LCA was conducted out according to the procedure of ISO14040 which suggested Goal and Scope Definition, Life Cycle Inventory Analysis, Life Cycle Impact Assessment and Interpretation. In the Goal and Scope Definition, the functional unit was 1 m3 of CSO, the system boundary was construction and operation phases, and the operation period was 20 years. For the data collection and inventory analysis, input energies and materials from civil, architecture, mechanical and electric fields are collected from design sheet but the landscape architecture field is excepted. LCIA(Life Cycle Impact Assessment) was performed following the procedure of Eco-Labelling Type III under 6 categories which were resource depletion, eutrophication, global warming, ozone-layer destruction, and photochemical oxide formation. In the result of LCA, 83.4% of environmental impact occurred in the construction phase and 16.6% in the operation phase. Especially 78% of environmental impact occurred in civil works. The Global warming category showed the highest contribution level in the environmental impact categories. For the analysis on potential environmental impact reduction, the reduction and increased of environmental impact which occurred on construction and operation phases were compared. In the case of considering only the operation phase, the result of the comparison showed that 78% of environmental impact is reduced. On the other hand, when considering both the construction and operation phases, 50% of environmental impact is increase. Therefore, this study showed that eco-friendly material and construction method should be used for reduction of environmental impact during life cycle, and it is strongly necessary to develop technology and skills to reduce environmental impact such as renewable energies.

• 보건교육건강증진학회지
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• 제27권1호
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• pp.21-34
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• 2010

Objectives: The objective of this study was to investigate risk factors for falls in the elderly by life-cycle. Methods: This study used the data on 435 male and female elderly generated from a survey taken at 21 Welfare Centers for the Elderly in Seoul. The incidence of demographic characteristics, physical changes brought about with ageing, health-related behavior, chronic diseases, and environmental characteristics on falls in the elderly was analyzed. Hierarchical Logistic Regression analysis was also conducted to investigate the incidence by life-cycle (early-mid-late stage) and the results were used for predicting falls. Results: The incidence of risk factors on falls varied across life-cycle. Among the elderly in the early (ages from 65 through 74), marital status, the existence of a companion, the quality of sleep, the chronic diseases, and the condition of the bathroom floor were found to be related to falls. Among those in the mid-stage (ages from 75 through 84), sex, marital status, the existence of a companion, hearing capacity, sense of balancing, chronic diseases, the exclusive use of rooms, and the side bar with bath tub were found to affect falls. Finally, for the elderly in their late stage (85 years of age and older), drinking and vision were found to be related to falls. Conclusion: The incidence of risk factors on falls was found to vary according the stage in the elderly. A key implication of this finding is that falls prevention programs and interventions must be catered to specific age sub-groups.

• Reproductive and Developmental Biology
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• 제35권4호
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• pp.463-468
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• 2011

This study investigated the changes of plasminogen activators (PAs) activity, expression and localization of tissue plasminogen activator (tPA) and urokinase plasminogen activator (uPA) during the estrous cycle in pigs. Estrous cycle was sorted into three group by pre-ovulation (Pre-Ov), post-ovulation (Post-Ov) and early to mid-luteal stages (Early to mid-L). Analysis for immunohistochemistry was confirmed by location of tPA and uPA. Porcine uterus tissue was cut into $1{\times}1$ cm squares, and were incubated in DMEM/F-12 medium for 1 h at $38^{\circ}C$, 5% $CO_2$ for measurement of PA activity. Western blotting was implemented for measurement of PA quantity. In results, the blood vessels and secretory glands were increased in Post-Ov stage than Pre-Ov and Early to mid-L stages. The tPA and uPA was located mainly within lumen of blood vessels and secretory glands. The PA activity in Post-Ov ($0.99{\pm}0.03$) stage were significantly (p<0.01) higher than Pre-Ov stage ($0.51{\pm}0.03$) and Early to mid-L stage ($0.21{\pm}0.04$). Expression of PAs were significantly (p<0.05) higher in Early to mid-L stage than other stages. These results indicate that PAs activity and expression may change in uterus tissue during the estrous cycle in pigs.

• 대한기계학회논문집A
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• 제40권7호
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• pp.653-658
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• 2016

가스터빈엔진의 고온 부품은 초내열 합금 재료를 이용하며, 냉각설계 적용으로 형상이 복잡하여 정밀 주조 과정을 거치게 된다. 터빈 부품에 주로 적용이 되는 일방향 응고 및 단결정 재료는 제조 과정에서 결정립 성장 방향이 설계와 다르게 섭동을 가지게 되며, 이는 각 방향에 대한 재료 상수의 섭동을 유발하여 응력 분포의 변화와 함께 피로 수명에 큰 산포를 야기하게 된다. 본 연구에서는 일방향 응고 재료 노즐에 대하여 결정립 성장 방향의 섭동에 대한 구조 건전성의 영향을 저주기 피로 수명을 통해 확인하여, 향후 제작 허용값에 대한 제안 및 좀 더 정교한 통계적 접근이 필요함을 확인하고자 한다. 이를 위해 복합 열전달 해석을 통해 금속 온도 분포를 계산하고 이를 근거로 구조 해석 및 저주기 피로 수명을 계산하였다.