• Food Science and Biotechnology
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• 제17권6호
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• pp.1285-1288
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• 2008

The purpose of this study was to characterize and investigate the immune activity of CpG oligodeoxynucleotides (ODNs) from Bifidobacterium longum. Bacterial CpG motifs have attracted considerable interests because of their immunomodulatory activities. Genomic DNA from B. longum was prepared and amplified for 4 different 180-188-mer double-stranded ODNs (BLODN1-BLODN4). When immune cells (RAW 264.7 murine macrophages and JAWS II dendritic cells) with these ODNs were treated, BLODN4 induced the highest immune activity. To assess the effectiveness of the CpG sequences within BLODN4, single-stranded 40-mer ODNs containing CpG sequences (sBLODN4-1, sBLODN4-2) were synthesized. sBLODN4-1 induced higher level of cytokines such as interleukin (IL)-12p40 and tumor necrosis factor (TNF)-$\alpha$ by macrophage and IL-6 and TNF-$\alpha$ by dendritic cells than did sBLODN4-2. The results suggest that CpG ODNs-enriched components of B. longum might be useful as an immunomodulatory functional food ingredient.

• 대한원격탐사학회지
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• 제26권3호
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• pp.361-371
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• 2010

In recent, interests regarding open source software for geo-spatial processing are increasing. Open source remote sensing (OSRS) is regarded as one of the progressing and advanced fields in remote sensing. Nevertheless, analyses or application cases regarding OSRS are not enough for general uses or references. In this study, three kinds of OSRS software in consideration of international popularity, types of functionalities, and development environments are taken into account: OSSIM, Opticks, and ORFEO Toolbox (OTB). First, functional comparison with respect to these is carried out on the level of the preliminary survey. According to this investigation, OTB is chosen as the most applicable OSRS software in this study. Running on OTB, NIX format importing module and database connecting module are implemented for widely general uses and further application. As for an example case, airborne image of NIX format is used to region growing segmentation algorithm in OTB, and then the results are stored and retrieved in PostGIS database to test implemented modules. Conclusively, local customization and algorithm development using OSRS software are necessary to build on-demand applications from the developers' viewpoint.

• BMB Reports
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• 제55권5호
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• pp.238-243
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• 2022

Autism or autism spectrum disorder (ASD) is a behavioral syndrome characterized by persistent deficits in social interaction, and repetitive patterns of behavior, interests, or activities. The gene encoding Methyl-CpG binding protein 2 (MeCP2) is one of a few exceptional genes of established causal effect in ASD. Although genetically engineered mice studies may shed light on how MeCP2 loss affects synaptic activity patterns across the whole brain, such studies are not considered practical in ASD patients due to the overall level of impairment, and are technically challenging in mice. For the first time, we show that hippocampal MeCP2 knockdown produces behavioral abnormalities associated with autism-like traits in rats, providing a new strategy to investigate the efficacy of therapeutics in ASD. Ketamine, an N-Methyl-D-aspartate (NMDA) blocker, has been proposed as a possible treatment for autism. Using the MeCP2 knockdown rats in conjunction with a rat model of valproic acid (VPA)-induced ASD, we examined gene expression and ASD behaviors upon ketamine treatment. We report that the core symptoms of autism in MeCP2 knockdown rats with social impairment recovered dramatically following a single treatment with ketamine.

• 한국수학교육학회지시리즈A:수학교육
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• 제50권3호
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• pp.263-284
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• 2011

We took note of the fact that there were not many studies on improvement of mathematics learning in the field of statistics for the minority students from the families who belonged to the Low-SES. This study was to help them understand the concepts and principles of mathematics, motivate them for mathematics learning, and have them feel familiar with it. The subjects were 12 students from the low-SES families among the sophomores of 00 High School in Gyeonggi-do. Although it could not be achieved effectively in the short-term of learning for the slow learners, their understanding of basic concepts and confidence, interests and concerns in statistical learning were remarkably changed, compared to their work in the beginning period. Our discourse classes using various topics and examples were well perceived by the students whose performance was improved up to the 3rd thinking level of Mooney's framework. Also, a meaningful instructional model for slow learners(IMSL) was found through the discourse.

• Strategy21
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• 통권36호
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• pp.121-149
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• 2015

This paper will examine some past and current issues concerning the Republic of Korea's national strategy, focusing predominantly upon how the ROK should respond to the urgent maritime-oriented strategy highlighted by the recent developments and achievements of national prosperity achieved during last three decades and identify some of successful cases in East Asia. Some consideration will also be given to more general emergent issues of trends and developments of East Asian countries which might affect to define the ROK's future national strategy in the context of its national grand strategy to enhance national interests and prosperity. ROK is especially dependent upon open Sea Lanes of Communication (SLOC) and its national security emphasizes the sea as the medium of geopolitical and geo-economic development, given the sea known as core geographic option remains that ROK is an important maritime power, ranking the world-level nation in term of GDP, sea-borne trade, container processing capability, shipbuilding capacity and so on. It should be apparent, therefore, that ROK's national strategic development depends upon the relationship between its peninsula geography and its national development based on sea-borne economic growth and its maritime-oriented future national strategy will be the best option to maintain its national development and economic prosperity.

• 한국진공학회:학술대회논문집
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• 한국진공학회 2014년도 제46회 동계 정기학술대회 초록집
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• pp.204.2-204.2
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• 2014

Among various metal oxides, ZrO2 is of particular interests and has received widespread attention thanks to its ideal mechanical and chemical stability. As a cheap metal, Ag nanoparticles are also widely used as catalysts in ethylene epoxidation and methanol oxidation. However, the nature of Ag-ZrO2 interfaces is still unknown. In this work, the growth, interfacial interaction and thermal stability of Ag nanoparticles on ZrO2(111) film surfaces were studied by low-energy electron diffraction (LEED), synchrotron radiation photoemission spectroscopy (SRPES), and X-ray photoelectron spectroscopy (XPS). The ZrO2(111) films were epitaxially grown on Pt(111). Three-dimensional (3D) growth model of Ag on the ZrO2(111) surface at 300 K was observed with a density of ${\sim}2.0{\times}1012particles/cm2$. The binding energy of Ag 3d shifts to low BE from very low to high Ag coverages by 0.5 eV. The Auger parameters shows the primary contribution to the Ag core level BE shift is final state effect, indicating a very weak interaction between Ag clusters and ZrO2(111) film. Thermal stability experiments demonstrate that Ag particles underwent serious sintering before they desorb from the zirconia film surface. In addition, large Ag particles have stronger ability of inhibiting sintering.

• 한국간호교육학회지
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• 제16권2호
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• pp.321-329
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• 2010

Purpose: The survey was performed to explore nurses' attitudes toward migrant wives in Korean society. Method: Four hundred thirty-eight respondents were recruited from 2 acute hospitals from 2 different geological areas. The attitude inventory to measure attitude toward migrant wives was utilized, which includes 6 factors such as prejudice, reliability, offensiveness, interests, acceptance, and influence. Result: The overall attitude was slightly positive (3.23) and reliability was the only non-positive scoring factor. Among the general characteristics education level showed a significant difference in 5 factors consistently compared to other characteristics. Conclusion: It can be concluded that Korean nurses tend to take a neutral to slightly positive attitude toward migrant wives. Therefore, any influence from nurses' attitudes related to migrant wives can be ignored. Obstacles or barriers which could hamper nursing care for migrant wives need to be identified and studies of strategies to overcome any existing barriers are called for.

• 한국생활과학회지
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• 제22권1호
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• pp.201-213
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• 2013

This study was conducted to identify adults' knowledge, attitude, dietary behavior, and lifestyle for cancer prevention, and to examine the relation between these variables. The participants were 414 adults in the Jeonbuk area. The data were analyzed using Pearson correlation coefficients, ANOVA and Duncan test with SPSS v. 12.0. The score for participants' knowledge about cancer was 23.98 points of a possible 30, the score for attitude towards cancer was 44.46 points of a possible 55, the score for preventive dietary behavior for cancer was 36.79 points of a possible 55, and their score for preventive lifestyle for cancer was 29.76 points of a possible 40. The knowledge, attitude towards cancer, dietary behavior, and lifestyle for cancer prevention showed significant differences according to the general characteristics (e.g., age, religion, monthly income, educational level, job, health condition, and interests). There was a significant positive correlation between knowledge about cancer, attitude towards cancer, dietary behavior, and lifestyle for cancer prevention. Dietary behavior for cancer prevention showed a positive correlation with lifestyle for cancer prevention. In conclusion, it is necessary to consider the related factors for the development and implementation of systematic education programs that can encourage and promote preventive health behavior for cancer among adults.

• 융합보안논문지
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• 제10권4호
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• pp.13-19
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• 2010

시대의 흐름에 따라 기업의 지속적인 비지니스 연계 보증을 위하여 IT의 비중이 높아지면서, IT가 조직의 하나의 부분으로서 작용하는 것이 아닌 전사적인 차원에서 정보화 사회의 경쟁 화두로서 인식되어가고 있다. 정보보안 거버넌스는 정보의 무결성, 서비스 연속성, 정보자산의 보호라는 3가지 목적으로 시작된다. 이는 기업 거버넌스에 필수적이며 투명한 부분이 되어야 하고, IT프레임워크와 연계되어야 한다. 기존의 정보보안 거버넌스 프레임워크는 그 범위가 넓어 소규모 기업 거버넌스와 이해관계를 가지지 못한 문제점이 있다. 따라서 본 논문은 단순화된 정보보안 거버넌스 프레임워크를 제안하여, 문제점을 해결하고, 제안하는 프레임워크의 안전성 분석과 효율성 분석을 통하여 제안 방법의 효율성에 관하여 알아보았다.

• 대한지구과학교육학회지
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• 제7권1호
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• pp.110-118
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• 2014

The purpose of this study was to compare the career awareness and social contribution consciousness between the elementary science gifted students and the general students. For this, survey was taken by 201 gifted students and 216 general students. Methods used are Cronbach alpha, frequency, percentage, independent t-test and Pearson's correlation coefficient. The results are as follows : 1. The gifted students have higher career awareness than the general students. The gifted students recognize their own interests, aptitudes and talents which they are concerned. 2. The gifted students have higher social contribution consciousness than the another. This shows that the gifted students have desire to be respected and positive view of social contribution. 3. There is a positive correlation between career awareness and the social contribution consciousness. According to the past studies, students' household economic status affect their view or grade which they get.. Based on these results, we suggest that a development of educational program for career awareness and social contribution consciousness which can improve gifted students' social responsibility consciousness is necessary.