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The association of abdominal obesity, obesity and parathyroid hormone in Korean adults (aged≥50 years): The Korea National Health and Nutrition Survey, 2011 (50세 이상 한국 성인에서 비만과 부갑상샘호르몬의 관련성 -2011 국민건강영양조사에 근거하여)

  • Lee, Kyu Su;Yoon, Yo Sang;Yoon, Hyun
    • Journal of the Korea Academia-Industrial cooperation Society
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    • v.16 no.6
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    • pp.3882-3888
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    • 2015
  • The present study was conducted to assess the relationship between obesity and abdominal obesity and Parathyroid hormone (PTH) in adults aged 50 or older (n=3,305) using 2011 Korean National Health and Nutrition Examination Survey (KNHANES) data, which represents national data in Korea. Key study results were as follows: First, the PTH levels increased significantly with an increase in Body mass index (BMI) (p=0.003), shown by sIAD levels after adjusted the variables that affect sIAD levels (age, gender, SBP, DBP, and 25(OH)D). These were $66.25{\pm}0.89ng/dL$ for Normal weight (BMI, < $23.0kg/m^2$), $67.83{\pm}1.07 ng/dL$ for Overweight (BMI, $23.0-24.9kg/m^2$), $70.71{\pm}0.94ng/dL$ for Obesity (BMI,${\geq}25.0kg/m^2$). Second, the PTH level of abdominal obesity group ($69.30{\pm}0.80ng/dL$) was significantly higher (p=0.017) than non-abdominal obesity group ($66.63{\pm}0.74ng/dL$). In conclusion, BMI and waist measurement are positively associated with the PTH levels in Korean adults.

QUALITATIVE UNCERTAINTY PRINCIPLES FOR THE INVERSE OF THE HYPERGEOMETRIC FOURIER TRANSFORM

  • Mejjaoli, Hatem
    • Korean Journal of Mathematics
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    • v.23 no.1
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    • pp.129-151
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    • 2015
  • In this paper, we prove an $L^p$ version of Donoho-Stark's uncertainty principle for the inverse of the hypergeometric Fourier transform on $\mathbb{R}^d$. Next, using the ultracontractive properties of the semigroups generated by the Heckman-Opdam Laplacian operator, we obtain an $L^p$ Heisenberg-Pauli-Weyl uncertainty principle for the inverse of the hypergeometric Fourier transform on $\mathbb{R}^d$.

Effects of the Molting-Hormone Mimetid Insecticide Tebufenozide: on Chironomus riparius Larvae (탈피교란물질인 Tebufenozide가 Chironomus riparius (Diptera: Chironomidae)에 끼친 영향)

  • 곽인실;이원철
    • Korean Journal of Environmental Biology
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    • v.21 no.3
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    • pp.286-291
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    • 2003
  • We investigated the effects of molting-hormone insecticide tebufenozide on D7 (the day of hatching from egg) larvae of the midge Chironomus riparius in growth developments. D7 instar larvae were exposed test concentrations were chosen control, 10${\mu}g \;L^{-1}$, 30${\mu}g \;L^{-1}$, 60${\mu}g \;L^{-1}$ and 100${\mu}g \;L^{-1}$ of tebufenozide. In general, dead larvae showed 16% on the next day after insecticide treatments (D12), and observed 44% from D12 to D16 in this exposed days. Dead larvae of C. riparius was abruptly increased on D12 and also continuously increased along the days in 10${\mu}g \;L^{-1}$ treatments. The converged day was from D12 to D16 at move 30${\mu}g \;L^{-1}$ treatments in this study. Therefore, dead larvae obviously increased along these concentrations of tebufenozide. In control condition,78% of the test individuals have grown the pupae. But the larvae have developed the pupa stage from 5% to 17% of the test organism in 10${\mu}g \;L^{-1}$ and 30${\mu}g \;L^{-1}$ treatments. And 75% of the test individuals was arrived the adult through the molting process in control condition. While the other condition was rarely observed the adult. Usually, the emerged period of the test individuals was gathered the D26-D29 in control. The dead pupa showed from D19 to D20 in 30${\mu}g \;L^{-1}$ treatments, D32 in control and D33 in 10${\mu}g \;L^{-1}$ treatments. The observed periods of dead pupa were D32-D34 in control and D33-D37 in 10${\mu}g \;L^{-1}$ treatments. Consequently, due to molting hormone disruption, development of midge was postponed relatively low concentration such as 10 treatments of tebufenozide.

Effect of noise and reverberation on subjective measure of speech transmission performance for elderly person with hearing loss in residential space (주거 공간에서 고령자 청력손실을 고려한 소음 및 잔향에 따른 음성 전송 성능의 주관적 평가)

  • Oh, Yang Ki;Ryu, Jong-Kwan;Song, Han-Sol
    • The Journal of the Acoustical Society of Korea
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    • v.37 no.5
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    • pp.369-377
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    • 2018
  • This study investigated the effect of noise and reverberation on subjective measure of speech transmission performance for elderly person with hearing loss in residential space through listening test. Floor impact, road traffic, airborne, and drainage noise were employed as the residential noise, and several impulse responses were obtained through room acoustical computer simulation for an apartment building. Sound sources for the listening test consisted of residential noises and speech sounds for boh the young (the original sound) and the aged (the sound filtered out by filters with frequency responses of hearing loss of 65 years elderly person). In the listening test, subjects evaluated speech intelligibility and listening difficulty for the presented word ($L_{Aeq}$ 55 dB) at three noise levels ($L_{Aeq}$ 30, 40, 50 dB) and three reverberation times (0.5, 1.0, 1.5 s). Results showed that the residential space with noise level lower than equal to 50 dB ($L_{i,Fmax,AW}$) for jumping noise and 40 dB ($L_{Aeq}$) for road traffic, airborne, and drainage noise had speech intelligibility of 90 % and over and listening difficulty of 30 % and below. Speech intelligibility and listening difficulty for the aged sound source was shown to be 0 % ~ 5 % lower and 2 % ~ 20 % higher than those for the young sound source, respectively.

Comparison of middle-aged women's bodice pattern using 3D data -focused on the DC Suite program-

  • Cha, Su-Joung
    • Journal of the Korea Society of Computer and Information
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    • v.23 no.1
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    • pp.91-102
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    • 2018
  • The purpose of this study is to develop an excellent bodice prototype that is adapted to the body shape of middle-aged women using 3D measurement data. In the evaluation of appearance, S pattern 4.00, B pattern 2.80, E pattern 2.40, L pattern 1.40 were shown in order, and the best fit of S pattern was evaluated as excellent. As a result of looking at the color distribution chart to find out the amount, E pattern and S pattern were not space in the front bust, armhole, and the back waist line. The B pattern and the L pattern were marked in blue because of insufficiency space in the back neck. As a result of evaluation the amount of air gap in the clothing, the air gap of the bust was 0.12, which is the largest pattern of B. Next, the L pattern appears as a tight circle with smallest air gap in the order of the S pattern 0.096, the E pattern 0.08, and the L pattern 0.003. The S pattern was evaluated to be the most appropriate for the body shape of middle-aged women. But the waist and back were slightly tight. Middle-aged women have larger shoulder-related items and larger waist circumference. Therefore, when you set the perimeter item, you should add 1-2cm of space amount and give extra space to the circumference area.

Urinary Excretion of Racemic Fenfluramine in Rat (흰쥐에서 펜플루라민이성질체의 뇨중 배설)

  • Chung, Hee-Sun;Park, Mee-Jung;Jin, Won-Tack;Yang, Won-Kyung;Choi, Hwa-Kyung;Yoo, Young-Chan
    • YAKHAK HOEJI
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    • v.42 no.6
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    • pp.576-582
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    • 1998
  • Fenfluramine, an anorectic agent, is widely abused as a diet pill in Korea because it is freely marketed in China without any regulation. The optical isomers of fenfluramine hav e different phamacological actions: d-form is used as an anorectic agent, while l-form as a neuroleptic agent. To investigate the metabolism when racemic fenfluramine was administered orally, the urinary excretion of fenfluramine was studied in rats. The enantiomeric separation of fenfluramine was performed on achiral column by gas chromatography using (S)-N-(trifluoroacetyl)-l-prolyl chloride (TFP) as a derivatizing agent. After administration of 15mg/kg of racemic fenfluramine to rats, d-, l-fenfluramine and its metabolites d- and l norfenfluramine in urine were determined by chromatographic separation of TFP derivatives on DB-1 at retention time of 11.2, 11.8, 8.4 and 8.6 min respectively. Urinary recoveries of d and l-fenfluramine in rat were 0.42-5.9O% and 0.18-1.20% respectively in urine specimens collected during first 24hr. The comparison in the levels of isomers showed that d- fenfluramine were higher than l-form, while d-norfenfluramine were lower than l-form. The ratios between parent compound and metabolite revealed that d-norfenfluramine to d-fenfluramine ranged from 1.0 to 4.4, while the ratio of l-norfenfluramine to l-fenfluramine was 8.2-21.1 indicating that l-fenfluramine is metabolized faster than the d-isomer.

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Anti-Oxidative and Inhibitory Effect of Saussurea involucrata on MMP-1 in UVA-irradiated Human Dermal Fibroblast (설련의 항산화능와 사람 섬유아세포에서 UVA에 의한 MMP-1발현 저해효과)

  • Sim, Gwan-Sub;Kim, Jin-Hwa;Na, Young;Lee, Dong-Hwan;Lee, Bum-Chun;Zhang, Yong-He;Pyo, Hyeong-Bae
    • Journal of the Society of Cosmetic Scientists of Korea
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    • v.31 no.4 s.54
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    • pp.329-335
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    • 2005
  • In order to investigate the effects of Saussurea involucrata on (relationship between) aging (and Saussurea involucrata), we examined the activities of antioxidation, in vitro MMP inhibition and UVA-induced MMP-1 expression in human dermal fibroblasts. S. involucrata showed scavenging activities radicals and reactive oxygen species (ROS) with the $IC_{50}$ values of $3.89{\mu}g/mL$ against 1,1-diphenyl-2-picrylhydrazyl (DPPH) radical and $67.29{\mu}g/mL$ against superoxide radicals in the xanthine/xanthine oxidase system, respectively. At the concentration of $1000{\mu}g/mL$, S. involucrata showed 93.27% inhibition on lipid peroxidation of linoleic acid. S. involucrata inhibited the activities of MMP-1 in a does-dependent manner and the $IC_{50}$ value calculated from semi-log plots was $97.18{\mu}g/mL$. Also, UVA induced MMP expression in human dermal fibroblasts was reduced 42.86% by treatment with S. involucrata, and MMP-1 mRNA expression was reduced in a dose-dependent manner. Therefore S. involucrata was able to significantly inhibit MMP expression in protein and mRNA level. All these results suggested that S. involucrata might act as an anti-aging agent by antioxidation and reducing UVA-induced MMP-1 production.

O-Alkylation Using Ag2O; Synthesis of Novel 4-Alkyloxy-2-phenylcarboxamidyl-1-tosylpyrrolidines (산화은을 이용한 O-알킬화 반응; 새로운 4-알킬옥시-2-페닐카복사미딜-1-토실피롤리딘 유?체의 합성)

  • Park, Myeong Suk
    • Journal of the Korean Chemical Society
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    • v.45 no.6
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    • pp.549-554
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    • 2001
  • For the development of new COX-2 inhibitor, novel compound were synthesized through induction an arylsulfonyl group to 1-position, an arylcarboxamidyl group to 2-position and an alkyl group to 4-position of L-proline. We started from 4-hydroxy-L-proline, the 4-methylphenylsulfonyl of 1-position was introduced through N-tosylation and the carboxylic acid group was protected by esterification. We sucessfully converted to a various derivatives 4b-d for O-alkyl-(or aralkyl)ation of 4-position using silver oxide as catalysis. The 4-alkyloxy-1-tosyl L-prolines 5b-d were synthesized through base-hydrolysis for the deprotection of carboxylic acid. Final compound 1,2,4-substituted pyrrolidines, 4-alkyloxy-2-phenylcarboxamidyl-1-tosyl pyrrolidines 6a-d were synthesized through the condensation of arylamine with 3 and 5b-d using DCC.

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SMALL DATA SCATTERING OF HARTREE TYPE FRACTIONAL SCHRÖDINGER EQUATIONS IN DIMENSION 2 AND 3

  • Cho, Yonggeun;Ozawa, Tohru
    • Journal of the Korean Mathematical Society
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    • v.55 no.2
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    • pp.373-390
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    • 2018
  • In this paper we study the small-data scattering of the d dimensional fractional $Schr{\ddot{o}}dinger$ equations with d = 2, 3, $L{\acute{e}}vy$ index 1 < ${\alpha}$ < 2 and Hartree type nonlinearity $F(u)={\mu}({\mid}x{\mid}^{-{\gamma}}{\ast}{\mid}u{\mid}^2)u$ with max(${\alpha}$, ${\frac{2d}{2d-1}}$) < ${\gamma}{\leq}2$, ${\gamma}$ < d. This equation is scaling-critical in ${\dot{H}}^{s_c}$, $s_c={\frac{{\gamma}-{\alpha}}{2}}$. We show that the solution scatters in $H^{s,1}$ for any s > $s_c$, where $H^{s,1}$ is a space of Sobolev type taking in angular regularity with norm defined by ${\parallel}{\varphi}{\parallel}_{H^{s,1}}={\parallel}{\varphi}{\parallel}_{H^s}+{\parallel}{\nabla}_{{\mathbb{S}}{\varphi}}{\parallel}_{H^s}$. For this purpose we use the recently developed Strichartz estimate which is $L^2$-averaged on the unit sphere ${\mathbb{S}}^{d-1}$ and utilize $U^p-V^p$ space argument.