• Journal of the Korean Institute of Telematics and Electronics
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• 제22권2호
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• pp.75-81
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• 1985

In low current injection level, the output signal of the 12 L is damaged and disturbed by the external loads (capacitance, resistance, current). Thus the uncertainty of the circuit can be increased .'This paper makes an analysis on the influences which the external loads have upon the 12 L-inverter function. It compares and analyzes the calculated result and measured result about the variation of rise time and fall time by means of computer simula-tions and experiments.

• Proceedings of the PSK Conference
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• 대한약학회 2002년도 Proceedings of the Convention of the Pharmaceutical Society of Korea Vol.2
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• pp.155-160
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• 2002

A series of modified oligonucleotides containing a phosphorothioate (P=S) backbone and a six-membered azasugar (6-AZS) as a sugar substitute in a nucleotide were synthesized and tested for their ability to inhibit the human immunodeficiency virus type I(HIV-l) in vitro without the aid of any transfecting agents. While P=S oligonucleotides with natural nucleotides had little anti-HIV-l activity, the six-membered azasugar nucleotide (6-AZN)-containing P=S oligonucleotides (AZPSONs) potently inhibited the HIV-l/SHIV replication and syncytium formation (ECso = 0.02-0.2 /lM) without cytotoxicity up to 100 /lM. DBM-2198, the most effective in anti-HIV-l activity among the AZPSONs, consists of random sequence and five 6¬AZNs evenly distributed in 18 nucleotides. DBM-2198 showed strong antiviral activity against, not only laboratory strains, but also primary isolates and even drug-resistant strains of HIV-I. DBM-2198 was much more effective than ddI or ddC in its anti-HIV-l activity in vitro. Particularly noteworthy is that the anti-HIV-l activity of DBM-2198 was better than that of AZT with respect to its long-lasting efficacy after a single treatment. Nevertheless, the antiviral activity of the AZPSONs was very specific to HIV-I. Poliovirus, or even simian immunodeficiency virus (SIV), was not inhibited by the AZPSONs. Taken together, our results strongly suggest that AZPSON can be used as a safe and effective AIDS-therapeutic drug against a broad spectrum of HIV -1 strains.

• Korean Journal of Crystallography
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• 제8권2호
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• pp.119-123
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• 1997

The complex [Ni(L)]I2 (1) (L:3,5,10,12-Tetramethly-1,4,8,11-tetraazacyclotetradecane) has been prepared and characterized by X-ray diffraction methods. The complex 1 crystallized in the orthorhombic system, space group Pcab with cell parameters a=13.293(1) Å, b=28.550(7) Å, c=10.804(1) Å, z=8. Least-squares refinement of 1 led to a R(Rw) factor of 0.043 (0.046) for 1851 observed reflections of Fo>3o (Fo). The crystal structure of 1 has a slightly distorted square-planar geometry and adopts the trans-III conformation.

• Tuberculosis and Respiratory Diseases
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• 제59권1호
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• pp.53-61
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• 2005

Background : Cardiac troponin I (cTnI) is a specific marker of myocardial injury. It is known that a higher level of cTnI is associated with a poor clinical outcome in patients with acute coronary syndrome. An elevation in cTnI is also observed in various noncardiac critical illnesses. This study evaluated whether cTnI is useful for predicting the prognosis in noncardiac critically ill patients. Methods : From June 2003 to July 2004 at Gyeongsang National University Hospital, we enrolled 215 patients (male:142, female:73, mean age:$63{\pm}15$ years ) who were admitted for critical illness other than acute coronary syndrome at the medical intensive care unit(ICU). The severity score of critical illness (SAPS II and SOFA) was determined and serum cTnI level was measured within 24 hours after admission to the ICU. The mortality rate was compared between the cTnI-positive (${\geq}0.1{\mu}g/L$) and cTnI-negative ($cTnI<0.1{\mu}g/L$) patients at the $10^{th}$ and $30^{th}$ day after admission to the ICU. The mean cTnI value was compared between the survivors and non-survivors at the $10^{th}$ and $30^{th}$ day after admission to the ICU in the cTnI-positive patients. The correlation between cTnI and the severity of the critical illness score (SAPS II and SOFA) was also analyzed in cTnI-positive patients. Results : 1) The number of cTnI-negative and positive patients were 95(44%) and 120(56%), respectively. 2) The mortality rate at the $10^{th}$ and $30^{th}$ day after admission to the ICU was significantly higher in the cTnI-positive patients (29%, 41%) than in the cTnI-negative patients (12%, 21%)(p<0.01). 3) In the cTnI-positive patients, the mean value of the cTnI at the $10^{th}$ and $30^{th}$ day after admission to the ICU was significantly higher in the non-survivors ($4.5{\pm}9.2{\mu}g/L$, $3.5{\pm}7.9{\mu}g/L$) than in the survivors($1.8{\pm}3.6{\mu}g/L$, $2.0{\pm}3.9{\mu}g/L$) (p < 0.05). 4) In the cTnI-positive patients, the cTnI level was significantly correlated with the SAPS II score (r=0.24, p<0.001) and SOFA score (r=0.30, p<0.001). Conclusion : The cTnI may be a useful prognostic marker in noncardiac critically ill patients.

• Proceedings of the KSPS conference
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• 대한음성학회 2000년도 7월 학술대회지
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• pp.178-178
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• 2000

This paper IS concerned with adults' foreign language aquisition and intends to research the relationship between the mother tongue's phonetic system (L1) and the perception of the foreign language (L2), in this paper Polish and Korean. The questions that are to help to define the aforementioned relationship are I) how Polish perceive Korean vowels, 2) how Koreans perceive Polish vowels, and 3) how Koreans perceive Korean vowels pronounced by Poles. In order to identify L2's vowels, the listeners try to fit them into the categories of their own language (L1). On the one hand, vowels that are the same in both languages and those that are articulated where no other vowel is articulated, have the best rate of recognition. For example, /i/ in both languages is a front close vowel and in both languages there are no other front close vowels. Therefore, vowels /i/ (and /a/) have the best rate of recognition in all three experiments. On the other hand, vowels that are unfamiliar to the listeners do not seem to have the worst rate of recognition. The vowels that have the worst rate of recognition are those, that are similar, but not quite the same as those of L1. This research proves that "equivalence classification prevents L2 learners from producing similar L2 phones, but not new L2 phones, authentically" (Flege, 1987). Polish speakers can pronounce unfamiliar L2 vowels "more authentically" than those similar to L1 vowels. However, the difference is not significant and this subject requires further research (different data, more informants).

• Journal of the Korean Institute of Telematics and Electronics
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• 제16권2호
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• pp.7-14
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• 1979

Design considerations of I2L are discussed with particular emphasis on the upward current gain of the npn transistor, 6J Several test structures have been fabricated to measure the DC and AC characteristics of the I2L basic cell and the base current components of the npn transistor. A T flip-flop has also been designed and fabricated using the I2L technology. The upward current gain of 10 the speed -power product of the 2.6pJ/gate and the minimum propagation delay time of 36 nsec have been obtained from the test structure. The maxmum toggle frequency of the T flip -flop has been measured to be 3.5 MHz.

• East Asian mathematical journal
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• 제6권2호
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• pp.167-182
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• 1990

The relationships between submodules of a module and ideals of the endomorphism ring of a module had been studied in [1]. For a submodule L of a moudle M, the set $I^L$ of all endomorphisms whose images are contained in L is a left ideal of the endomorphism ring End (M) and for a submodule N of M, the set $I_N$ of all endomorphisms whose kernels contain N is a right ideal of End (M). In this paper, author defines an H-invariant module and proves that every submodule of an H-invariant module is the image and kernel of unique endomorphisms. Every ideal $I^L(I_N)$ of the endomorphism ring End(M) when M is H-invariant is a left (respectively, right) principal ideal of End(M). From the above results, if a module M is H-invariant then each left, right, or both sided ideal I of End(M) is an intersection of a left, right, or both sided principal ideal and I itself appropriately. If M is an H-invariant module then the ACC on the set of all left ideals of type $I^L$ implies the ACC on M. Also if the set of all right ideals of type $I^L$ has DCC, then H-invariant module M satisfies ACC. If the set of all left ideals of type $I^L$ satisfies DCC, then H-invariant module M satisfies DCC. If the set of all right ideals of type $I_N$ satisfies ACC then H-invariant module M satisfies DCC. Therefore for an H-invariant module M, if the endomorphism ring End(M) is left Noetherian, then M satisfies ACC. And if End(M) is right Noetherian then M satisfies DCC. For an H-invariant module M, if End(M) is left Artinian then M satisfies DCC. Also if End(M) is right Artinian then M satisfies ACC.

• Bulletin of the Korean Mathematical Society
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• 제52권2호
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• pp.531-540
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• 2015

Let (R, m) be a Noetherian local ring, I an ideal of R, and A an Artinian R-module. Let $k{\geq}0$ be an integer and $r=Width_{&gt;k}(I,A)$ the supremum of length of A-cosequence in dimension > k in I defined by Nhan-Hoang [8]. It is shown that for all $t{\leq}r$ the sets $$(\bigcup_{i=0}^{t}Att_R(Tor_i^R(R/I^n,A)))_{{\geq}k}\;and\\(\bigcup_{i=0}^{t}Att_R(Tor_i^R(R/(a_1^{n_1},{\cdots},a_l^{n_l}),A)))_{{\geq}k}$$ are independent of the choice of $n,n_1,{\cdots},n_l$ for any system of generators ($a_1,{\cdots},a_l$) of I.

• Microbiology and Biotechnology Letters
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• 제27권4호
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• pp.292-297
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• 1999

Overproduction of L-ornithine by mutant strains isolated from Brevibacterium detoglutamicum BK1046 was investigated. The strain was a L-ornithine auxotroph and exhibited culture instability during fermentation. Through a sequential screening effort, a highly stable strain with lless revertant formation was finally selected and designated B. ketoglutamicum BK52 (KCTC0141BP). It prouduced L-ornithine at a high concentration (above 9 g/L) independent of subculture or cultivation time, and also had a very low tendency of revertant formation. In a long-term storage, this strain maintained its cell stability and productivity of L-ornithine to a reasonable range.

• Magazine of the Korean Society of Agricultural Engineers
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• 제44권6호
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• pp.49-60
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• 2002

This study was conducted to estimate the design flood by the determination of best fitting order of LH-moments of the annual maximum series at six and nine watersheds in Korea and Australia, respectively. Adequacy for flood flow data was confirmed by the tests of independence, homogeneity, and outliers. Gumbel (GUM), Generalized Extreme Value (GEV), Generalized Pareto (GPA), and Generalized Logistic (GLO) distributions were applied to get the best fitting frequency distribution for flood flow data. Theoretical bases of L, L1, L2, L3 and L4-moments were derived to estimate the parameters of 4 distributions. L, L1, L2, L3 and L4-moment ratio diagrams (LH-moments ratio diagram) were developed in this study. GEV distribution for the flood flow data of the applied watersheds was confirmed as the best one among others by the LH-moments ratio diagram and Kolmogorov-Smirnov test. Best fitting order of LH-moments will be derived by the confidence analysis of estimated design flood in the second report of this study.