• Title/Summary/Keyword: Kruskal-Wallis Test

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Association of PAH-DNA adducts and Urinary PAH metabolites influenced by polymorphisms of xenobiotic metabolism enzymes in industrial wase incinerating workers (산업폐기물 소각장 근로자에서 요중 PAHs 대사산물과 혈중 aromatic-DNA adducts)

  • ;Masayoshi Ichiba
    • Environmental Mutagens and Carcinogens
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    • v.22 no.4
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    • pp.303-311
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    • 2002
  • This study evaluated the concentrations of urinary metabolites of polycyclic aromatic hydrocarbons (PAHs) in industrial waste incineration workers. The effect of genetic polymorphisms of xenobiotic metabolism enzymes on urinary concentration of PAH metabolites was assessed. And, aromatic DNA adduct levels were also determined in total white blood cells. Fifty employees were recruited from a company handling industrial wastes located in Ansan, Korea: non-exposed group (n=21), exposed group (n=29). Sixteen ambient PAHs were determined by GC/MSD (NIOSH method) from personal breathing zone samples of nine subjects near incinerators. Urinary 1-hydroxypyrene glucuronide (1-OHPG), a major pyrene metabolite, was assayed by synchronous fluorescence spectroscopy after immunoaffinity purification using monoclonal antibody 8E11 (SFS/IAC). Multiplex PCR was used for genotyping for GSTMI/TI and PCR-RFLP for genotyping of CYP1A1 (MspI and Ile/Val). PAH-DNA adducts in peripheral blood WBC were measured by the nuclease P1-enhanced postlabeling assay. Smoking habit, demographic and occupational information were collected by self-administered questionnaire. The range of total ambient PAH levels were 0.00-7.00 mg/㎥ (mean 3.31). Urinary 1-OHPG levels were significantly higher in workers handling industrial wastes than in those with presumed lower exposure to PAHs (p=0.006, by Kruskal-Wallis test). There was a statistically significant dose-response increase in 1-OHPG levels with the number of cigarettes consumed per day (Pearson correlation coefficient=0.686, p<0.001). Urinary 1-OHPG levels in occupationally exposed smoking workers were highest compared with non-occupationally exposed smokers (p=0.053, by Kruskal-Wallis test). Smoking and GSTMI genotype were significant predictors for log-transformed 1-OHPG by multiple regression analysis (overall model R²=0.565, p<0.001), whereas smoking was the only significant predictor for log-transformed aromatic DNA adducts (overall model R²=0.249, p=0.201). Aromatic DNA adducts was also a significantly correlation between log transferred urinary 1-OHPG levels (pearson's correlation coefficient=0.307, p=0.04). However, the partial correlation coefficient adjusting for Age, Sex, and cigarette consumption was not significant (r=0.154, p=0.169). The significant association exists only in individuals with the GSTMI null genotype (pearsons correlation coefficient=0.516, p=0.010; partial correlation coefficient adjusting for age, sex, and cigarette consumption, r=0.363, p=0.038). Our results suggest that the significant increase in urinary 1-OHPG in the exposed workers is due to higher prevalence of smokers among them, and that the association between urinary PAH metabolites and aromatic DNA adducts in workers of industrial waste handling may be modulated by GSTMI genotype. There results remain to be confirmed in future larger studies.

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The Assessment of Blood Glucose Distribution according to the Fasting State and Glycemic Control Indicators for Diabetes Screening (금식 여부에 따른 혈당치 분포와 당뇨병 선별을 위한 혈당조절지표의 평가)

  • Kwon, Pil Seung;Rheem, Insoo
    • Korean Journal of Clinical Laboratory Science
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    • v.48 no.4
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    • pp.312-320
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    • 2016
  • This study analyzed the distribution of the blood glucose level according to the fasting status. Moreover, a relationship was analyzed between fasting blood glucose level and glycemic control indicators. A total of 707 outpatients, who visited Dankook University Hospital, were included and classified into either the fasting group and the non-fasting group. The mean blood glucose level of each group was calculated and analyzed by sex, age, and clinic. In addition, blood glucose, HbA1c, fructosamine, and 1,5-AG were measured in 153 fasting health check-up patients, and the correlation between the blood glucose level and glycemic control indicators was evaluated. Blood glucose averages between the two groups (non-fasting 111.9 vs. fasting 103.6 mg/dL) were different (p<0.05); and the mean difference was lower in women (4.8 mg/dL) than in men (12.2 mg/dL). A significant difference of the median glucose values among the age groups was only observed in the non-fasting group (Kruskal-Wallis test, p<0.01), and not in the fasting group. A 1,5-Anhydroglucitol was estimated to be significantly correlated with the fast blood glucose level in the range of the criteria of impaired fasting glucose (IFG). We presented an assessment of the distribution of blood glucose level in accordance with the fasting status among outpatients, and estimated that 1,5-anhydroglucitol was well correlated with the fasting blood glucose than fructosamine and HbA1c, through the analysis of results of health screening subjects. It is suggested that the use of glycemic indicators that reflect short-term blood glucose control can be used together with the blood glucose measurement in the screening of diabetes mellitus.

Relationship between Problem Solving Ability, Critical Thinking Disposition, Creativity, Self Efficacy and Nursing Process Competence of Nursing Students (간호대학생의 문제해결능력, 비판적 사고 성향, 창의성, 자기효능감과 간호과정 수행능력과의 관계)

  • Yang, Sun-Hee;Sim, In-Ok
    • The Journal of the Korea Contents Association
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    • v.16 no.5
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    • pp.612-622
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    • 2016
  • The purpose of this study was to identify the relationship between problem solving ability, critical thinking disposition, creativity and nursing process competence of nursing students. The participants in the study were 246 nursing students enrolled in 2nd year of a BSN program in S city, Korea. Data were collected from June 10 to June 20, 2015 using a structured questionnaire. Relationship between general characteristics and solving ability, critical thinking disposition, creativity and nursing process competence was analyzed by t-test, ANOVA and Kruskal-wallis. Correlation among problem solving ability, critical thinking disposition, creativity and nursing process competence was analyzed by pearson correlation coefficient. There was a statistically significant difference in problem solving with the reason for application, major satisfaction. There was a significant positive correlation between problem solving ability, critical thinking disposition, creativity and self efficacy. Nursing process competence was't a significant between problem solving ability, critical thinking disposition, creativity and self efficacy. These findings show that there is a need to develop strategies to improve self efficacy and nursing process competence for student nurses.

The Effects of Pollutants into Sub-basin on the Water Quality and Loading of Receiving Streams (하천 수질 및 부하량에 미치는 유역 내 오염원의 영향)

  • Han, Mideok;Son, Jeeyoung;Ryu, Jichul;Ahn, Kihong;Kim, Yongseok
    • Journal of Korean Society of Environmental Engineers
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    • v.36 no.9
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    • pp.648-658
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    • 2014
  • We examined the effects of pollutants into sub-basin on the water quality and loading based on data surveyed during January-December 2013 from 13 sites of 5 streams in the Jinwi watershed. We used the contour plot and Kruskal-Wallis rank sum test to analyze seasonal variation of water quality and loading and Pearson correlation analysis to assess the relationships between pollutants and loadings. The significantly higher seasonal variation were SS, TN and TOC as compared to other water quality constituents (P < 0.001). A significant interaction existed between the effects of human population and the effects of discharge of Sewage Treatment Plant (STP) on water quality and loading, especially for the spring and winter seasons. It is necessary to control discharge water of sewage and wastewater from industrial facilities and to make full use of the watershed management system such as TMDLs in operation since 2012 for improvement in stream water quality.

Activity Factors and Differences in Activity by Period of Red-eared Slider Turtles (Trachemys scripta elegans) in Ansan Reed Wetland (안산갈대습지에 서식하는 붉은귀거북(Trachemys scripta elegans)의 활동 요인과 시기에 따른 활동 차이)

  • Jung, Ji-Hwa;Lee, Woo-Shin
    • Korean Journal of Environment and Ecology
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    • v.33 no.6
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    • pp.645-653
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    • 2019
  • The purpose of this study was to understand the factors that affected activities and differences in seasonal activities of the invasive red-eared slider turtle (Trachemys scripta elegans) at Ansan reed wetland in Sangnok-gu, Ansan, Gyeonggi Province, the Republic of Korea. We installed nine nets in the study region to capture turtles and checked the nets twice a day for 154 days from April 28 to September 28 2013. In total, 60 individuals, including 12 juveniles, 26 adult males, and 22 adult females, were captured in 96 of 308 net checks. The multiple regression analysis of 12 environmental factors was conducted to analyze activity factors of red-eared slider turtle by assuming the number of turtles captured for a week to be the indicator of the activeness of the turtles. The result showed that the daylength was the only environmental factor that significantly affected the turtles' activity (p<0.001), and none of the other factors showed a significant correlation. The highest activity was recorded at the end of May, which was the beginning of the reproductive period. The daylength during the breeding season was significantly different from that during other seasons (Kruskal-Wallis test, p<0.001). The information about the relationship between environmental factors and species in habitat can be useful for the management of invasive alien species in the future.

A study of various factors related to satisfaction of complete denture wearers (총의치 장착자의 의치 만족도와 관련된 요인에 관한 연구)

  • Byun, Jin-Soo;Huh, Yoon-Hyuk;Cho, Lee-Ra;Park, Chan-Jin
    • Journal of Dental Rehabilitation and Applied Science
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    • v.32 no.2
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    • pp.109-116
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    • 2016
  • Purpose: The aim of this study was to evaluate correlations between denture satisfaction and various factors related to patients' and wearing dentures. Materials and Methods: Total 43 edentulous patients were recalled and they were wearing complete dentures fabricated more than one year ago. For patients' subjective assessment, the questionnaire based on the various literatures was developed and applied to patients for data acquisition. In addition, correlations were evaluated between subjective assessment and denture satisfaction score. For statistical analysis, Spearman correlation coefficient, multiple regression analysis, Mann-whitney U test and Kruskal-Wallis test were used to found out what the most considerable factors to denture satisfaction score (P < 0.05). Results: Denture satisfaction score of maxilla was higher than mandible (P < 0.05). In functional aspects, maxillary denture were received a favorable evaluation. Especially fit and pain causing were highly correlated to satisfaction. Gender, age, using period, visiting times after manufacturing denture were unrelated to satisfaction. But previous experience was related to denture satisfaction. Conclusion: Denture satisfaction was determined by a combination of various factors related to patients.

Variation in the Index of Dental Plaque Removal and Practice Assessment after Instruction on Toothbrushing (칫솔질 교육 후 치면세균막 지수와 수행도의 변화)

  • Kim, Ki-Eun;Ahn, Eunsuk;Han, Ji-Hyoung
    • Journal of dental hygiene science
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    • v.15 no.2
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    • pp.220-225
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    • 2015
  • This study was conducted to examine O'leary index, patient hygiene performance (PHP) index, and toothbrushing practice assessment in subjects of college students in 20s who had been randomly selected. The purpose of this study is to examine if it is easy for rolling method which is recommended by many dental professionals in Korea to implement and to effectively remove dental plaque. Also, the correlations between dental plaque index and toothbrushing practice assessment with the course of time was confirmed, after instruction session on toothbrushing was provided. STATA 11.0 (StataCorp) was used for analysis. There was no significant difference on the three ways of O'leary index, PHP index, and toothbrushing practice assessment in using rolling method, bass technique and toothpick method when comparing the average resulting from first to third instruction session on toothbrushing. O'leary index, PHP index, and toothbrushing practice assessment were inspected with Kruskal-Wallis test which is used for non-parametric statistics. They were checked three times: the first, before the toothbrushing instruction was given; the second, two weeks after the toothbrushing session was given; and the third, 4 weeks after the session. The results are as follows: O'leary index stood at the lowest in the first experiment but showed the highest in the second (p=0.0001). PHP index was the highest level in the first trial and decreased in the second time, but increased again in the last examination (p=0.0001). Toothbrushing practice assessment also showed a similar tendency with PHP index (p=0.0001). In conclusion, rolling method is not the best option for everyone, and it is thought that more various toothbrushing ways need to be reviewed and recommended to people. Also, institutional framework is required for the continuous education on toothbrushing to be in place as the effectiveness of the education is decreased with time.

THE EFFECT OF NAOCL TREATMENT AND STERILIZATION PROCEDURES ON THE CORROSION OF ENDODONTIC FILES (차아염소산나트륨 처리와 멸균법이 근관 치료용 파일의 부식에 미치는 영향에 관한 연구)

  • Yang, Won-Kyung;Ra, Yoon-Sik;Lee , Young-Kyoo;Son, Ho-Hyun;Kim, Mi-Ri
    • Restorative Dentistry and Endodontics
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    • v.30 no.2
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    • pp.121-127
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    • 2005
  • A variety files made of stainless steel (S-S) or nickel-titanium (Ni-Ti) are used during endodontic treatment. The purpose of tt)is study was to evaluate the corrosion susceptibility of S-S and Ni-Ti endodontic files. Three brands of files were used for this study: $K-flex^{(R)}$ S-S files (Maillefer, USA), $Profile^{(R)}$ Ni-Ti files (Maillefer, USA), $K-3^{(R)}$ Ni-Ti files (SybronEndo. USA). 120 files of each brands (21mm, ISO size $\#20$) were divided into 12 groups according to 1) sterilization methods using Autoclave or Ethylene Oxide (E-O) gas, 2) Irrigation solutions using $5.25\%$ NaOCl or Saline, 3) the number of sterilization (1, 5, 10 times), After above procedures, each of the files was inspected by three examiners with a light microscope and camera at X25. Each file was judged and ranked according to the following criteria: 0;, no corrosion, 1; mild corrosion, 2; moderate corrosion, and 3; severe corrosion. The files of high score were examined under the Scanning Electron Microscope. Data were statistically analyzed with the Kruskal-Wallis test (p < 0.05). Most of the ten time-autoclaved files had showed mild to moderate corrosion. But, one or five time-autoclaved files did not show corrosive surface. NaOCl treatment and E-O gas sterilization did not influence on corrosion. There was a significant difference in corrosion susceptibility between sterilization methods and the number of autoclaving. However, there was no significant difference between brands and file materials.

Comparative esthetic evaluation of anterior zone with immediate, early, and delay implantation (전치부 영역 임플란트의 식립 시기에 따른 심미적 평가)

  • Kim, Jung-Hwa;Seo, Seong-Yong;Kim, Na-Hong;Yu, Jung-Hyun;Lee, Dong -Woon
    • Journal of the Korean Academy of Esthetic Dentistry
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    • v.26 no.1
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    • pp.17-23
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    • 2017
  • Purpose: This retrospective study is to evaluate whether the timing of implant placement and the result of esthetic outcomes are related. Materials and Methods: Among the patients who had undergone single implant surgery on anterior area from 2010 to 2013 in Veterans Health Service Medical Center, 34 implants in 27 patients (24 male and 3 female) were selected and categorized into 3 groups according to the timing of placement, which are group D (Delay), group E (Early) and group I (Immediate). Aesthetic indices used included the Pink Esthetic Score (PES). It has 7 variables scores, such as mesial papilla, distal papilla, a level of soft-tissue margin, soft-tissue contour, alveolar process, soft-tissue color, and soft-tissue texture. Each variable ranges from 0 to 2, therefore total 14 points are highest. All patients were received by regular follow-up at least 1-year. One examiner measured PES on the intraoral photos. Each patient was considered as a statistical unit for statistical analysis. Statistical analyses were performed using a commercially available statistical software (SPSS Statistics 21.0, IBM Corp., Armonk, NY, USA). Kruskal-Wallis test was used for inter-group comparisons. Statistical significance was set at P<0.05. Result: Mean score in Group D, Group I, and Group E were $11.5{\pm}1.5$, $11.4{\pm}1.8$, and $11.3{\pm}1.8$ respectively. In Kruskal-Wallis test, there are no differences (P=0.989). Conclusion: In this limited study suggests that clinical aesthetic results can be achieved with all treatment protocols. Finally, various factors can be considered to produce the esthetic results.

A comparative study of the improvement after different self-assessment methods of tooth preparation (치아 삭제의 다른 자가 평가 방법 후 개선에 대한 비교 연구)

  • Kim, JungHan;Son, Keunbada;Lee, Kyu-Bok
    • Journal of Dental Rehabilitation and Applied Science
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    • v.35 no.4
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    • pp.220-227
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    • 2019
  • Purpose: The purpose of this study was to compare the degree of tooth preparation abilities of students according to three self-assessment methods. Materials and Methods: forty-eight sophomores in Kyungpook National University College of Dentistry were divided into three experimental groups. Students performed tooth preparation of the left mandibular first molar for full gold crown. They performed self-assessment using the three methods (visual, digital, and putty index self-assessment group), and reperformed tooth preparation. An intraoral scanner was used to scan each tooth model (prepared tooth and unprepared tooth), and data were acquired in standard tessellation language (STL) file format. The STL files of prepared tooth and unprepared tooth were superimposed using the 3-dimensional analysis software (Geomagic control X). And the reduction amount was measured. In the statistical analysis, all values of reduction amount were analyzed with the Wilcoxon signed rank test and Kruskal-Wallis test (α = 0.05). Results: The three self-assessment methods showed statistically significant differences (P < 0.001). The putty index self-assessment group showed the highest reduction in error than the digital self-assessment method. Conclusion: Within limitations of this study, students showed significant differences in improvement of tooth preparation ability according to the three self-evaluation methods.