• 한국한의학연구원논문집
• /
• 제11권1호
• /
• pp.19-32
• /
• 2005

본고에서는 역대 본초서(本草書)의 간행(刊行)을 통해 본초학(本草學)이 역사적 변천 과정을 거치면서 어떻게 발전해 왔는지를 주제로 살펴보고자 한다. 이를 위해 각 시대별로 가장 특징적인 본초서를 위주로 대표적인 본초 명저의 간행과 이것이 의미하는 시대적 특징과 본초학적 발전상을 요약하였다. 아울러 대표 명저 중 우리 의학에 도입되어 깊은 영향을 끼친 본초서의 흔적과 조선판의 간행 사항을 조사하여 소개함으로서 한국한의학에 미친 영향성을 알아보았다.

• 한국자원식물학회지
• /
• 제7권2호
• /
• pp.137-141
• /
• 1994

In order to establish utilijzation of medicinal herb as vegetable by Hydroponics, the present studies were conducted to investigate the effect of temperature and light on the seed germination ofmedicinal herb. The results obtained are summaried as follows. The lower and upper temperaturelimit for herb germination was 10'c and 30'c within which the optimum was 20'C. Germinationof medicinal herb was similar in light and dark condition.

• 한국식품저장유통학회지
• /
• 제10권2호
• /
• pp.213-218
• /
• 2003

재래식 된장의 품질을 고급화하기 위해 재래식 된장과 각종 한약제와 약초류를 달리 첨가하여 제조한 두 종류의 약용 된장들을 6개월간 숙성시키면서 성인병에 관련된 몇 가지 생리 기능성의 변화를 조사하였다 약용 된장들의 고혈압을 예방하는 엔지오텐신 전환효소(ACE) 저해활성은 숙성기간이 길어짐에 따라 급격히 감소하여 숙성 6개월 후에 39.0%∼51.7%을 보였고 혈전용해활성은 숙성 6개월후에 10.4∼11.3 U를 보였다. 약용 된장들의 전자공여능은 제조직후 95%∼97%을 보였고 숙성 기간이 길어짐에 따라 큰 변화가 없었으며 SOD 유사활성은 숙성 6개월 후에 모두 10% 내외를 보였다. 약용 된장(I)의 tyrosinase 저해활성은 숙성 기간이 길어짐에 따라 증가하여 숙성 6개월 후에 상온물 추출물에서 97.6%의 높은 활성을 보였다. 6개월 숙성된약용 된장들의 조단백질과 총당 함량은 각각 14%와 33%로 재래식 된장보다 높았다.

• 생약학회지
• /
• 제49권1호
• /
• pp.55-64
• /
• 2018

Recently, it has been a big issue to distinguish the dried roots of Cynanchum wilfordii and C. auriculatum in health functional food market. The original plant species of Cynanchi Wilfordii Radix belong to the Asclepiadaceae family is differentially described in the national pharmacopoeia of Korea, China and Japan. Owing to the morphological similarities of the dried roots of this plant to those of C. auriculatum, which is often misidentified in Korean herbal medicine marketplace, distinguishing these two species is exceedingly difficult. The purpose of this study was to compare the conventional-PCR with the real-time PCR for detection of C. wilfordii and C. auriculatum DNA. We also tried to realize a quantitative real-time PCR assay using species-specific matK primers, which allowed us to estimate the ratio of C. willfordii and C. auriculatum using varying ratios of mixed genomic DNA template from the two species. The differentiation of intentional and unintentional mixture in this study would be applied to food safety management and can be helpful for protection of consumer's right and cultivators.

• 한국약용작물학회지
• /
• 제12권1호
• /
• pp.53-59
• /
• 2004

국내 한약재 시장에서 유통되고 있는 백출 건재약재의 기원을 판별하고자 해부형태적 특징과 종 특이적인 SCAR 마커 (SAjR2, SAmR1)를 적용한 실험 결과는 다음과 같다. 해부형태적 특징으로 A. japonica에서는 주피에 코르크층이 매우 발달하여 있었고, 코르크층 내부 또는 아래에 석세포대가 연속적으로 발달하고 있었다. 유실은 A. japonica에서 뿌리횡단면에 전체적으로 다수 분포하여 잘 발달하고 있었으며 피충부분과 잘 발달된 방사조직 내에서도 목섬유다발이 다수 관찰됐다. 또한 유세포 내의 침상 결정물도 A. macrocephala보다 많이 함유하고 있었다. 이러한 특징들을 종합한 결과, 국내 유통 국산 및 수입 백출은 모두 A. japonica의 해부형태적 특징을 따르고 있어 A. japonica로 동정되었다. 한편 RAPD clone으로부터 개발된 A. japonica 특이적인 SAjR2를 이용하여 PCR 한 결과 모든 샘플에서 600bp 크기의 한국백출 특이적인 밴드가 형성되었으며, A. macrocephala 특이적인 SAmR1을 이 용한 결과에서는 작물시험장에서 재배중인 A. macrocephala에서만 1200 bp크기의 특이적인 밴드가 형성되어, 시중에서 유통되고 있는 한국백출과 중국백출은 모두 A. japonica로 동정되었다. 결론적으로 해부형태적 특성과 SCAR 마커는 A. japonica와 A. macrocephala 기원식물의 동정과 유통 건재 약재를 판별하기에 유용한 방법이었다.

• 한국의사학회지
• /
• 제28권2호
• /
• pp.1-13
• /
• 2015

Purpose : Local medicinal herb festivals present the history of the Korean medicine and cultural resources in the regions to play an important role in attracting tourists, vitalizing local economy, and improving the local image. Therefore, it is important to understand the origin of the festival and grasp historical and cultural meaning of local medicinal herb festivals. Methods : I compared the books and articles presented in the reference list. Results & Conclusions : Local medicinal herb festivals originates from traditional yangnyeongsi. Since the $17^{th}$ century, yangnyeongsi has grown up as a special market. Implementation of the Daedong Act promoted commodity and monetary economy that helped commerce and industry develop and market grow up. It also made changes in the social status system and yangnyeongsi has been such a historical phenomenon appeared in this social background. The growth of yangnyeongsi contributed to the progress in the private medicine that triggered the gradual transfer of power in the medicine to the private sector which has long been held by the government. In yangnyeongsi, there were many cultural events to attract visitors. It's the same case in China that preserves stages that were used for cultural events in the medicine market to pass down the historic sites while those in Korea are disappearing as yangnyeongsis are being pulled out of the city areas to the suburban areas due to the redevelopment projects. For this reason, restoration of the place for traditional yangnyeongsi should be taken into account through local medicinal herb festivals.

• 한국자원식물학회지
• /
• 제35권4호
• /
• pp.428-434
• /
• 2022

감초의 건조 방법 및 감마선 조사를 이용하여 미생물 저감화 효과를 확인하였다. 또한 감마선 조사 때문에 성분 변화가 있는지 확인하기 위해서 HPLC를 이용하여 유효성분인 Glycyrrhizin, Liquiritin의 성분 변화를 확인하였다. 건조 방법으로는 마이크로웨이브 건조, 동결건조, 열풍건조, 자연건조 순으로 미생물 저감화에 효과적이었고, 감마선 조사 후에는 모든 건조 시료에서 미생물이 사멸되었음을 확인하였으며, 감마선 조사에 따른 유효성분 함량의 수치 변화는 있었으나 통계적으로 유의성이 없게 나타났다.

• 한국포장학회지
• /
• 제13권2호
• /
• pp.43-50
• /
• 2007

The production, distribution, and consumption of Korean medicinal herbs have increased every year because of an increase of health considerations. But there are no sufficient standardization procedures in packaging and distribution systems related to these herb products. The standardization of packaging material and dimension could be a good addition for establishing proper quality control methods for Korean medicinal herbs. Medicinal herbs deteriorate under physical, chemical and biological hazards such as oxidation, textural change under high moisture content, color change by light, sanitation problems by insect invasion and contamination. Packaging standardization with proper functional packaging materials is critical to ensure the qualities of medicinal herbs. Also, storage and distribution efficiencies can be improved by achieving packaging dimension standardization. This review summarizes recent research trends related to quality evaluation methods and major quality deterioration factors of Korean medicinal herbs. This paper also offers reviews on some of problems and challenges in current packaging and distribution systems of medicinal herb industries and briefly suggests advanced quality control methods through packaging standardization.

• 한국한의학연구원논문집
• /
• 제11권1호
• /
• pp.1-18
• /
• 2005

As a result of study on the names of local medicinal herbs which described in Chobu (Chapter of Grass) of Korean medical book Bonchojeonghwa, we came to the following conclusions. 1) Compared with the existing domestic medical books' local medicinal herb names, those of Donguibogam had the closest relationship with Bonchojeonghwa. Out of local medicinal herb names described in Chobu of Bonchojeonghwa, a third is only shown in Bonchojeonghwa, and another third is same as those in Donguibogam. 2) The notation of local medicinal herb names in Bonchojeonghwa is not so consistent as Donguibogam. In Bonchojeonghwa, we can see many examples of inconsistent notations over the same thing. Moreover, there are some examples, which are suspected to be an expression of dialect. 3) In spite of close similarity between the names of local medicinal herbs in Bonchojeonghwa and Donguibogam, the author of Bonchojeonghwa doesn't seem to directly refer to or quote Donguibogam, because it doesn’t make sense that the author of Bonchojeonghwa intentionally referred to regular, consistent Donguibogam in irregular, inconsistent way. 4) In spite of very low possibility of direct reference or quotation among Bonchojeonghwa, Donguibogam and Bangyakhappyon, there are many examples of common format in its notation way on local medicinal herbs, which cannot be explained only as coincidence. And it tells us that there must be another publication which had been referred to or quoted by the said three medical books. 5) From the fact that there are a lot of examples of local medicinal herb names which doesn't show palatalization, or labialization, the names of local medicinal herbs described in Bonchojeonghwa must be the expression around 17th century.

• Natural Product Sciences
• /
• 제24권1호
• /
• pp.21-27
• /
• 2018

Psoriasis is an auto-immune skin disease, which is characterized by the excessive generation of plaques on the skin with typically a long-lasting red, itchy and scaly symptoms. Imiquimod, which has been used for the treatment of external genital warts, actinic keratosis, and superficial basal cell carcinoma, induced of psoriasis-like skin disorders with skin erythema and thickness in mice. In the present study, we tried to find the bioactive herbal extract against imiquimod-induced psoriasis-like skin disorder in mice. During the searching of the herbal extract with anti-psoriatic effect, the ethanolic extract of Cnidium officinale ameliorated imiquimod-induced psoriasis-like skin disorder in mice. The morphological evaluation, H&E staining and Psoriasis Area and Severity Index (PASI) score showed that ear and back thickness, and erythema induced by imiquimod were significantly reversed after the treatment of the cream of the ethanolic extract of C. officinale. The overexpressed myeloperoxidase (MPO) and keratin 6A levels were decreased by the treatment of C. officinale cream. Also, $IFN-{\gamma}$, c-fos and $I{\kappa}B-{\alpha}$ mRNA levels, which are related to the progression of psoriasis, were reduced by C. officinale cream. Thus, the ethanolic extract of C. officinale ameliorated psoriasis-like skin disorder induced by imiquimod and might be the therapeutic agent for psoriasis.