• 한국식품과학회지
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• 제44권3호
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• pp.356-361
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• 2012

다양한 식품 중에 널리 분포되어 있는 생리활성 성분 카페인과 일반의약품 성분 AAP, Asp 및 Ibu와의 혼용 시 상호작용에 의한 세포 독성 변화를 장관계 세포모델에서 조사하였다. 카페인은 정상 장관계 세포 INT 407 및 대장암 세포 HCT 116에 농도의존적인 독성을 나타내었고, $IC_{50}$ 수치는 각각 1.91과 2.45 mM로써 정상세포에 유의적으로 높은 독성을 나타내었다. 카페인과 각각의 약물을 세포에 24시간 동시 처리한 결과 전체적으로 현저한 독성의 변화현상은 발생하지 않았으나, 약물처리 시를 기준으로 한 카페인의 상대적 독성 및 카페인 처리 시를 기준으로 한 약물의 독성이 INT 407 세포에서 유의적으로 증가하였다. 동시 처리 시 약물에 의해 감소된 GSH를 비롯한 thiol성 물질의 세포 내 수준이 카페인 존재 시에 유의적으로 증가하였다. 한편 카페인과 약물을 각각 순서를 달리하여 전후로 처리하였을 때, 특히 HCT 116 세포에서의 약물의 상대적인 독성이 강화되는 현상을 보였다. 일반의약품 AAP, Asp 및 Ibu과 카페인을 다양한 조합에 의해 장관계 세포에 처리하였을 때 일부 상대적인 독성의 강화 또는 약화 현상이 나타났으나 전체적으로 두드러진 독성발현 빛 활성변화는 발견되지 않았다.

• 한국측량학회지
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• 제38권1호
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• pp.57-67
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• 2020

최근 스마트도시는 교통, 환경, 안전, 에너지 등 다양한 도시문제를 해결하기 위한 대안으로 주목받고 있다. 그러나 스마트도시의 개념, 동향, 정책 및 법제도에 관한 연구는 활발히 이루어지는데 비해서, 도시의 성장·정체·쇠퇴 과정 등 전 단계를 고려한 동태적 관점에서 스마트도시 서비스가 실제로 도시에 어떠한 영향을 미치는지에 대한 연구는 미흡한 실정이다. 따라서 도시를 인구, 산업, 교통, 환경, 주택, 토지 등의 하위 구성요소들이 상호간에 밀접하게 상호작용 하는 하나의 전체 시스템으로 보는 시각을 바탕으로, 도시가 시간의 흐름에 따라 어떻게 변화하는지 파악할 필요가 있다. 이에 본 연구는 시스템 다이내믹스 기법을 활용하여 안양시의 도시동태성이 장기적으로 어떠한 행태로 나타나는지 규명하고, 안양시의 스마트도시계획 등 관련 사업예산 투자가 도시동태성에 어떠한 영향을 미치는지를 분석하였다. 분석결과, 안양시는 성숙·안정형 도시에 해당되며 2040년까지 인구가 서서히 감소하는 것으로 나타났다. 구체적으로 안양시 인구는 2030까지 55만3천명 수준으로 감소하고 2040년까지 54만3천명 수준으로 감소하는 것으로 나타났다. 안양시 스마트도시계획(안)에 따라 스마트도시 사업예산을 투입하면 투자하지 않을 경우에 비해서 인구감소 완화, 사업체수 증가, 도시안전지수 개선, 평균 주행속도 개선 등의 효과가 있는 것으로 나타났다. 인구는 2040년 기준으로 예산 투입 이전보다 4000명 정도 증가하고 사업체수는 761개 증가하는 것으로 나타났다. 이러한 연구결과는 장기적인 관점에서 스마트도시 관련 정책의 효과를 파악하고 예측하는데 활용될 수 있다.

• 대한영양사협회학술지
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• 제10권2호
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• pp.205-217
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• 2004

This study was carried out to provide information on the effect of nutrition education program for diabetic patients at the Guri City's Public Health Center. Subjects of this study were 31 persons(male 7, female 24) who attended all courses of "2002 Diabetes Education Class". They were indicated as the 'education group'(EG). Eating and living habits of EG were investigated before the education. EG's weight and blood glucose (post prandial 2 hours, PP2) were examined as well. EG's PP2 reduction was compared with a 'control group'(CG) who didn't join any course in that class. All of the subjects were non-insulin-dependent diabetes mellitus(NIDDM) patients. EG's average age was 62.4$\pm$8.8. Before taking the course, EG's PP2 was 251.5$\pm$29.6mg/dl, and body mass index(BMI) was 26.3$\pm$2.3 on average. Most of them were stressed out from their daily lives and usually had no exercise. Most people of EG ate meals rapidly and liked sweet and fatty foods. After the course of training, EG's weight and BMI before the training were not decreased significantly. However, all of the EG's PP2s, which were measured 4 times(before the meal at the special lunch session, after 2 hours at this meal, after 2 weeks and 4 weeks dietary assembly), were decreased in comparison with the PP2 which was checked prior to joining the training. EG's average PP2 was more reduced than CG's one. In addition, all groups' PP2s were decreased for 8 weeks. After all, this nutritional education at the public health center was effective in glycemic control for diabetes mellitus patients. Especially, when the dietary assembly as practical training was included in the educational process, the patient's dietary intake and PP2 was improved more effectively. Therefore, this study suggests that nutrition work at public health centers is necessary for the Health Promotion Policy.

• 한국운동역학회지
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• 제19권2호
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• pp.297-309
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• 2009

이 연구에서는 피칭웨지 스윙 시 족저압력 측정기를 이용하여 평지, 오르막 내리막경사면에서의 족저압력분포의 메카니즘을 분석하여 운동역학적인 기초자료를 제공하고자 피험자는 KPGA 3명, KLPGA 3명을 대상으로 족저압력분포를 측정한 후 스윙시간, 동작특성, 평균족저압력 그리고 최대족저압력을 분석한 결과 경사면의 형태변화에 따른 스윙동작 시 구간별 시간변인과 족저압력변인들을 종합적으로 분석 결과 경사면에서의 스윙동작은 백스윙 과정에서 하지의 코일링 동작을 방해하는 요인이 될 수 있으며, 다운스윙과정에서도 체중분산을 최소화시키는 하지의 블로킹 동작과 이 후 릴리스 동작에도 부정적인 영향을 미치는 것으로 분석되었다. 또한 경사면은 스윙동작에 영향을 미칠 수 있는 많은 외적 요인들 중의 하나인데, 오르막경사면에서의 어드레스 자세는 하지의 움직임을 제한하기 때문에 약간 좁은 스탠스를 유지하고, 내리막경사에서는 반대로 하지의 더 큰 활동성을 막기 위하여 더 넓은 스탠스를 가져야 할 것으로 판단되며, 어드레스 자세에서 뿐만 아니라 오르막경사의 다운스윙 동안에도 가능한 신체균형을 유지시키기 위하여 체중을 왼발에 두어야 할 것으로 판단된다.

• 농약과학회지
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• 제15권4호
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• pp.357-365
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• 2011

농약을 살포하는 농작업자의 농약 노출 측정은 농약의 건강 위해성 평가에서 중요한 부분을 차지하기 때문에 정량적이고 신뢰성 있는 노출량의 측정을 위해서 노출 측정에 사용되는 재료와 기기/기구 및 방법은 포장 노출 시험 전에 미리 검증해야 한다. 본 연구는 유기인계 농약 중에서 살충제 fenthion을 대상으로 농작업자의 노출량 측정을 위한 분석/시험방법의 검증을 수행하였다. LOD는 0.01 ng, LOQ는 0.05 ng로 설정하였고, 표준 검량선의 직선성($R^2$ > 0.999)과 분석재현성(C.V. < 3%)은 매우 우수하였다. 또한 3수준(LOQ, 10LOQ, 100LOQ)으로 수행한 노출 시료(장갑, 양말, 마스크, 패치, 고체흡착제, 유리섬유필터) 중 fenthion의 회수율은 76~113%(C.V. < 3%)이었고, 호흡 노출 실험의 검증 중에서 포집효율은 95~105%이었다. 파과실험 결과 fenthion은 1차 고체흡착제 부분에만 존재하였다. 이와 같은 분석/실험법의 검증을 통하여 실제 포장 실험에서 유래한 노출 시료들을 신뢰성 있게 분석할 수 있는 방법을 확인/검증/확립하였다. 이러한 분석/시험법 검증은 실험실 수준에서 수행할 수 있고, 농약의 종류에 따라서도 크게 다르지 않기 때문에 신체 부위별 평균 체표면적이나, 평균 호흡량과의 조합을 통해서 농약 노출 연구에 적극적으로 활용될 것으로 판단한다.

• 대한지역사회영양학회지
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• 제7권2호
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• pp.177-187
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• 2002

This study was done to determine the factors associated with childhood overweight in 721 sixth grade elementary school students, in Busan. The students' heights, weights, waist circumferences and triceps-skinfold thicknesses were measured using standard techniques. Other data were collected using a questionnaire that included information about physical activity, television watching, and the amount of exorcise taken during leisure times, family history of diseases related to obesity: social data including family income, parents'education and occupations, eating behaviors; parental weights and heights; and parental activity levels. Childhood overweight was defined as a body mass index at or above the 85th percentile for age and sex. The prevalence of overweight revealed no significant difference between sexes, (24.2% in boys and 22.03% in girls). The risk of childhood overweight was significantly greater if either the mother or the father were overweight. The odds ratio for childhood overweight associated with maternal overweight was 5.045 (94% CI : 3.262-7.801), and 2.727 (95% CI : 1.764-4.218) was the case for parental overweight. Children having a history of hear diseases had higher odds ratios than those who did not. The odds ratios for overweight associated with income were not different. However, a higher odds ratio for overweight was observed in children whose fathers had only an elementary or middle school education than those whore fathers had a high school or college education. Children whose fathers' occupations were service workers or shopkeepers (OR : 3.314, 95% C = 1.851-5.934) or had no occupation (OR = 3.756, 95% CI : 1.898-7.430) had a treater risk of overweight than those whose fathers'were professionals or once workers. The risk of overweight increased in children having more irregular meal times and faster eating times, rather than those having an intake pattern of high energy and sugar containing floods. The amount of exercise taken during leisure times, and daily physical activity showed no difference between overweight and non-overweight children. However, television watching time, especially on weekends, was greater in overweight children than in non-overweight children. Television watching time was positively correlated with BMI, triceps-skin(31d thickness, waist circumference and waist/height ratio. Therefore, television watching was found to be a useful predictor of overweight in children. Television watching in children was negatively related to paternal activity levels, and positively related to parental television watching time. In fact, fathers whose children were overweight were physically less active than fathers whose children were non-overweight. Parents appeared to be a strong influence on their children's physical activity levels. In conclusion, a low family social class, defined on the basis of the father's occupation or education, parental overweight, increased television watching, and unhealthy physical activity levels in parents were all considered risk factors for childhood overweight. Among these, television watching time and lack of physical activity were considered to be the most important risk factors that could be easily modified for the prevention of and intervention in, overweight in children.

• 지역사회간호학회지
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• 제16권4호
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• pp.498-507
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• 2005

Purpose: The purpose of this study is to survey health requirements of middle-aged women and their families and to provide guidelines for developing nursing interventions by describing the process of family health maintenance experienced by middle-aged women and its conceptual system. Methods: To get saturated data, each of four researchers conducted two or three times of in-depth interview with eight middle-aged women aged between 40-64 years old and living in Seoul and Chuncheon from the 10th to the 30th of October 2004 and each interview was continued one or two hours. The Grounded theory adopted by Strauss & Corbin (1998) is a substantive theory that can explain the experiencing process of middle-aged women. Results: We found that the casual condition of family health maintaining by middle-aged women was 'confidence of health belief', and 'pouring by body moving' was found to be its phenomenon. A textual condition that might respond to the phenomenon was 'fatal roles acceptance', and intervening conditions that promote their family health were 'retracing' and 'gathering health information'. These intervening conditions impacted middle-aged women's confidence in family health and led them to take actions/interactions such as 'being a model of health', 'adapting to circumstances', 'do-it-myself', 'taking-care' 'harmonious mind' and 'the pursuit of cleanness'. These actions/interactions produced results such as 'being stronger', 'being unmanageable' and 'being fruitful'. Conclusions: Health confidence and practical health behaviors were observed in the process that the middle-aged female participants experienced unmanageable circumstances but they accepted their roles and responsibilities and recognized that they must be get stronger. The behaviors of health-together-with were divided into enthusiastic type, adaptation type and self-sacrificing type. Therefore middle-aged woman with the understanding of family health maintaining process as well as the theoretical system and practical principals needs to implement the intervention in acceptable level of family health process of preventing psychological and physical problems.

• 한국보건간호학회지
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• 제18권1호
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• pp.103-118
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• 2004

The purpose of this study was to understand the process and investigate basic theory of fatigue experience of shift work nurses. The present study adopted grounded theory methodology on fatigue of shift work nurses. The participants for this study were 15 shift work nurses who were in the age of 25 to 35, the clinical experience of 2 to 14 years and the work department of ICU. ER. ward and delivery room. The data were collected from 2000 to 2003 by using interviews and observations. The contents of the interviews were tape-recorded and were drawn through repeated method. And then were analyzed into the concept, subcategories, and categories with the open coding process and axial coding was done to identify the relationships of the concepts and categories according to the paradigm models. The core category generated, which was a central phenomena of the exhaustion process. The causal condition is change events. The central condition of exhaustion were sorted as physical discomfort, decreasing vigor, psychological instability, feeling of sleeping desire, changing face impression and being heavy body. The intervening condition were discovered as social$\cdot$ psychology$\cdot$physical resist and positive$\cdot$negative interaction strategies. The consequences of the fatigue process is the short term exhaustion relief and long term residual exhaustion. The fatigue process of this study was 'break through exhaustion' of change event-exhaustion-resist-resolve intervention-adaptation. This study offers better understanding on fatigue process of shift work nurses and may facilitate more appropriate interventive strategies to support, information and knowledges according to fatigue process.

• 대한간호학회지
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• 제25권3호
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• pp.441-456
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• 1995

This study was done to determine direct and in-direct nursing time in nursing units in hospital to ap-plied computer system and expect that those results contribute to measure efficiency of nursing practice and planning of nursing manpower. The design for study was a descriptive study. The study results are as follows. 1. Patients admitted to the Internal Medicine and General Surgery units were grouped into four. Group Ⅰ, 32.9% of the total patients, consisted patients whose condition was considered minor Group Ⅱ, 26.1%, was of those whose condition was considered moderate, Group Ⅲ, 41. 8%, moderate severe and Group Ⅳ, 29.2% the most severe. 2. Nursing intervention times by care type were as follows four minutes spent for suction eight minutes, for simple position change, ten minutes, for sheet change, seven minutes for a hot or cool compress, six minutes for dressing change, four minutes for Ⅰ.M. injection, six minutes for patient health education and five minutes for body temperature check. 3. Direct care time by patient group revealed the following : Group Ⅰ rquired 191.4 minutes, Group Ⅱ required 331.1 minutes, Group Ⅲ rquired 499.4 minutes, and Group Ⅳ rquired 1328.0 minutes. 4. The ratio of time for adequate nursing care and direct care time in the Internal Medicine and Goneral Surgery units was 67.4%-83.4% and 94.7%-99.3% in the Intensie Care Unit. 5. Average daily direct care time per patient was 5.5 hours in the Internal Medicine unit and 11.5 hours in the Intensive Care Unit. 6. Time spent in indirect care was 48.3 minutes for computer recording,34.8 minutes for giving and receiving patient information for shift duty, 28.0 minutes for eating and resting time, 26.6 minutes for transfering and identifying patients, 25.6 minutes for identifying Doctor's order, 23.9 minutes for recording vital signs. 7. Time spent in indirect care was 282.2 minutes by head nurses (charge nurses), 258.7 minutes by nurses and 261.6 minutes by nurse aids. 8. The average nurse's workload was 9.3 hours and daily indirect nursing time required 46.3%-50. 5% of above mentioned workload time. .9. The average daily indirect care time per patient was expected to be 57.7 minutes in the Internal Medicine unit and 3.3 hours in the Intensive Care Unit.

• 대한치과보철학회지
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• 제31권3호
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• pp.423-446
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• 1993

Titanium and its alloys are finding increasing use in medical devices and dental implants. The strong selling point of titanium is its resistance to the highly corrosive body fluids in which an implant must survive. This corrosion resistance is due to a tenacious passive oxide or film which exists on the metal's surface and renders it passive. Potentiodynamic polarization measurement is one of the most commonly used electro-chemical methods that have been applied to measure corrosion rates. And the potentiodynamic polarization test supplies detailed information such as open circuit, rupture, and passivation potential. Furthermore, it indicates the passive range and sensitivity to pitting corrosion. This study was designed to compare the corrosion resistance of the commonly used dental implant materials such as CP Ti, Ti-6A1-4V, Co-Cr-Mo alloy, and 316L stainless steel. And the effects of galvanic couples between titanium and the dental alloys were assessed for their useful-ness-as. materials for superstructure. The working electrode is the specimen , the reference electrode is a saturated calomel electrode (SCE), and the counter electrode is made of carbon. In $N_2-saturated$ 0.9% NaCl solutions, the potential scanning was performed starting from -800mV (SCE) and the scan rate was 1 mV/sec. At least three different polarization measurements were carried out for each material on separate specimen. The galvanic corrosion measurements were conducted in the zero-shunt ammeter with an implant supraconstruction surface ratio of 1:1. The contact current density was recorded over a 24-hour period. The results were as follows : 1. In potential-time curve, all specimens became increasingly more noble after immersion in the test solution and reached between -70mV and 50mV (SCE) respectively after 12 hours. 2. The Ti and Ti alloy in the saline solution were most resistant to corrosion. They showed the typical passive behavior which was exhibited over the entire experimental range. Therefore no breakdown potentials were observed. 3. Comparing the rupture potentials, Ti and Ti alloy had the high(:st value (because their break-down potentials were not observed in this study potential range ) followed by Co-Cr-Mo alloy and stainless steel (316L). So , the corrosion resistance of titanium was cecellent, Co-Cr-Mo alloy slightly inferior and stainless steel (316L) much less. 4. The contact current density sinks faster than any other galvanic couple in the case of Ti/gold alloy. 5. Ag-Pd alloy coupled with Ti yielded high current density in the early stage. Furthermore, Ti became anodic. 6. Ti/Ni-Cr alloy showed a relatively high galvanic current and a tendency to increase.