• Title/Summary/Keyword: Kinetic 모델

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Parameter Estimation in Enzymatic Reaction Model (효소반응 모델식에서의 매개변수 추정)

  • 채희정;김지현차형준유영제
    • KSBB Journal
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    • v.5 no.2
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    • pp.133-139
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    • 1990
  • A simple and convenient method was introduced to determine the kinetic parameters for various enzymatic reaction kinetics. The method based on integrated formular can be applied to the parameter estimations from a single experiment. A modified three-parameter model was applied for the parameter estimation in reversible reaction and the equilibrium substrate concentration could be also estimated. It is possible to identify the enzymatic reaction pattern by inspecting the parameter values and the square of the correlation coefficient.

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Adsorption Characteristics of Copper using Biochar Derived from Exhausted Coffee Residue (커피찌꺼기 biochar를 활용한 구리의 흡착특성)

  • Park, Jong-Hwan;Kim, Hong-Chul;Kim, Yeong-Jin;Kim, Seong-Heon;Seo, Dong-Cheol
    • Korean Journal of Environmental Agriculture
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    • v.36 no.1
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    • pp.22-28
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    • 2017
  • BACKGROUND: There is very limited knowledge of the effects of biochar derived from exhausted coffee residue on metal adsorption processes. Furthermore, only limited information is available on the adsorption mechanism of copper. The aim of this study was to evaluate the absorption behaviors of copper by biochar derived from exhausted coffee residue. METHODS AND RESULTS: Biochars produced by pyrolysis of exhausted coffee residue at $300^{\circ}C$(CB300) and $600^{\circ}C$(CB600) were characterized and investigated as adsorbents for the removal of copper from aqueous solution. The results indicated that the adsorption equilibrium was achieved around 2 h and the pseudo-second-order kinetic model fit the data better than the pseudo-first-order kinetic model. The maximum Cu adsorption capacities of CB600 by Freundlich and Langmuir isotherms were higher than those of CB300. The adsorption data were well described by a Langmuir isotherm compare to Freundlich isotherm. CONCLUSION: Our results suggest that exhausted coffee residue can be used as feedstock materials to produce high quality biochar, which could be used as adsorbents to removal copper.

Kinetic Modeling of Dewatering of Potato Slice When Soaked in Concentrated Solution (고농도 용액에 침지시 감자 절편의 동력학적 탈수 모델링에 관한 연구)

  • 최동원;신해헌
    • The Korean Journal of Food And Nutrition
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    • v.13 no.5
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    • pp.477-482
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    • 2000
  • For the purpose of explaining the dewatering phenomena of potato slice soaked in concentrated solution three models were proposed. Earlier model cannot explain the dewatering phenomena of potato slice in concentrated solution because of limiting its condition which is necessary to build a model. Therefore other three models were suggested and a model based on Fick\`s second law of mass transport at infinite plate conditions and numerical analysis was test model for explaining dewatering phenomena of potato soaked in concentrated solution. Apparent diffusion coefficient of water could be readily estimated from model III, and it could explain adequately the difference of the dewatering phenomena of various soaking conditions.

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Theoretical Consideration of the Modified Haldane Model of the Substrate Inhibition in the Microbial Growth Processes (미생물 성장 공정에서의 기질 저해에 관한 modified Haldane 모델의 이론적 고찰)

  • Hwang, Young-Bo
    • Applied Chemistry for Engineering
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    • v.19 no.3
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    • pp.277-286
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    • 2008
  • This paper deals with the theoretical derivation of the modified Haldane model of the substrate inhibition in the microbial growth processes. Based on the biological concepts of substrate-receptor complex working mechanisms, a new microbial kinetics of N-fold multiplex substrate inhibition and its generalization has been considered theoretically, which is natural expansion of the simple substrate inhibition mechanism in the enzyme reaction. As a result, the modified Haldane model of the substrate inhibition turns out to be a well-designed four-parameter kinetic model with a biological constant of the total substrate inhibition concentration.

Measurement of Flow Field in a Ginseng Cleaner Model Using PIV (PIV에 의한 인삼세척기 모델 내부의 유동계측)

  • 송치성
    • Journal of Advanced Marine Engineering and Technology
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    • v.25 no.1
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    • pp.139-145
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    • 2001
  • The objective of experimental study is to apply simultaneous measurement by PIV(Particle Image Velocimetry) to high_speed flow characteristics within ginseng cleaner model. Three different kinds of flow rate(15. 20, 27l/min) are selected as experimental condition. Optimized cross correlation identification to obtain velocity distribution, time-mean velocity distribution, velocity, profile, kinetic energy and turbulence intensity are represented quantitatively for the deeped understanding of the flow characteristics in a ginseng cleaner model.

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Toxicokinetic Models and Data Interpretation (독성동태 모델과 데이터의 해석)

  • 유선동
    • Toxicological Research
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    • v.18 no.4
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    • pp.311-324
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    • 2002
  • Toxicokinetic studies are intended to provide critical evaluation of drug disposition at toxico-logical doses and help understand the relationship between blood or tissue levels and the time course of toxic events. Relatively high dose levels wed in toxicokinetics, compared to pharmacokinetics, complicates absorption, protein binding, metabolism and elimination processes. In this mini review, frequently wed toxicokinetic models such as linear compartment models, physiological models, and nonlinear kinetic mod-ec are introduced. In addition, optimization of toxicokinetic studies, their role in the drug development process, and prediction oj human toxicokinetics based on animal data by interspecies scaling are briefly discussed.

Theoretical Model for the Electrical Resistance of Skin (피부의 전기적 저항에 대한 이론적 모델)

  • Oh, Seaung-Youl
    • Journal of Pharmaceutical Investigation
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    • v.26 no.3
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    • pp.207-213
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    • 1996
  • The kinetic change of electrical resistance of hairless mouse skin as a function of ionic strength of the bathing medium was determined from impedance measurements. After increasing (decreasing) the ionic strength of the bathing medium, resistance decreased (increased) continuously with time, finally reaching an equilibrium value. We have modelled this process, using nonsteady-state diffusion kinetics. The results show semi-quantitative correlation between theoretically derived and experimentally obtained values. Overall, this work provides further mechanistic insight into ion-conduction through the skin.

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Three-Dimensional Kinematic Model of the Human Knee Joint during Gait

  • Mun, Joung-Hwan;Seichi Takeuchi
    • Journal of Biomedical Engineering Research
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    • v.23 no.3
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    • pp.171-179
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    • 2002
  • It is well known that the geometry of the articular surface plays a major role in the kinematic and kinetic analysis to understand human knee joint function during motion. The functionality of the knee joint cannot be accurately modeled without considering the effects of sliding and lolling motions. We Present a 3-D human knee joint model considering sliding and rotting motion and major ligaments. We employ more realistic articular geometry using two cam profiles obtained from the extrusion of the sagittal Plain view of the representative Computerized Tomography image of the knee joint compared to the previously reported model. Our model shows good agreement with the already reported experimental results on Prediction of the lines of force through the human joint during gait. The contact point between femur and tibia moves toward the Posterior direction as the knee undergoes flexion, reflecting the coupling of anterior and Posterior motion with flexion/extension. The anterior/posterior displacement of the contact Point on the tibia plateau during one gait cycle is about 16 mm. for the lateral condyle and 25 mm. for the medial condyle using the employed model Also. the femur motion on the tibia undergoes lateral/medial movement about 7 mm. and 10 mm. during one gait cycle for the lateral condyle and medial condyle. respectively. The developed computational model maybe Potentially employed to identify the joint degeneration.

Development of the Calcium Alginate Bead Immobilized with $TiOSO_4$ for the Efficient Removal of Phosphorous (Phosphorous의 효율적인 제거를 위한 $TiOSO_4$ 고정화 Calcium Alginate Bead의 제조기법에 관한 연구)

  • Choi, Jae-Woo;Lee, Seung-Yeon;Chung, Seung-Gun;Lee, Sang-Hyup
    • Journal of Korean Society of Environmental Engineers
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    • v.33 no.3
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    • pp.162-166
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    • 2011
  • Phosphorous contaminated in the effluent from sewage treatment plants can cause the eutrophication in surface water bodies. In this study, a powder of titanium oxysulfate-sulfuric acid made of ion-exchange materials was immobilized in an alginate gel and this material was examined to evaluate its phosphorous removal efficiency. Equilibrium and kinetic studies were carried out to quantify the adsorption capacity and time dependent removal rate of phosphorous. Adsorption isotherms and kinetic parameters were obtained for the entrapped titanium beads with three different methods. Equilibrium data were analyzed using Langmuir adsorption isotherm model and found to be well fitted to the model. The maximum adsorption capacity for phosphorous by the titanium bead synthesized with the solution method was 92.26 mg/g. Kinetic data followed a pseudo-second-order kinetic model. Due to the low production cost and high adsorption capacity, the titanium bead synthesized by the solution method has a potential to be utilized for the cost-effective removal of phosphorous from wastewater.

The Experimental Study on the Absorbed Energy of Carbon/Epoxy Composite Laminated Panel Subjected to High-velocity Impact (고속 충격을 받는 Carbon/Epoxy 복합재 적층판의 흡수 에너지 예측에 대한 실험적 고찰)

  • Cho, Hyun-Jun;Kim, In-Gul;Lee, Seokje;Woo, Kyeongsik;Kim, Jong-Heon
    • Composites Research
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    • v.26 no.3
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    • pp.175-181
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    • 2013
  • The evaluation and prediction for the absorbed energy, residual velocity, and impact damage are the key things to characterize the impact behavior of composite laminated panel subjected to high-velocity impact. In this paper, the method to predict the residual velocity and the absorbed energy of Carbon/Epoxy laminated panel subjected to high velocity impact are proposed and examined by using quasi-static perforation test and high-velocity impact test. Total absorbed energy of specimen due to the high-velocity impact can be grouped with static energy and kinetic energy. The static energy are consisted of energy due to the failure of the fiber and matrix and static elastic energy, which are related to the quasi-static perforation energy. The kinetic energy are consisted of kinetic energy of moving part of specimen, which are modelled by three modified kinetic model. The high-velocity impact test were conducted by using air gun impact facility and compared with the predicted values. The damage area of specimen were examined by C-scan image. In the high initial impact velocity above the ballistic limit, both the static energy and the kinetic energy are known to be the major contribution of the total absorbed energy.