• 제목/요약/키워드: Kidney information

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Ultrasonography of Abdominal Organs in Cynomolgus Monkey (Macaca fascicularis) (Cynomolgus Monkey(Macaca fascicularis)에서의 복부 초음파에 관한 연구)

  • 김명철;김남중;이재일;이수진
    • Journal of Veterinary Clinics
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    • v.18 no.4
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    • pp.350-353
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    • 2001
  • The purpose of this study is to construct fundamental information about the ultrasonographic diagnosis for extrinsic and intrinsic abdominal disease. Normal ultrasonography of liver, gall bladder, spleen, kidney, urinary bladder, stomach, pylorus, duodenum, and heart of 4 cynomolgus monkey(Macaca fascicularis) were determined by use of ultrasonography. One cynomolgus monkey was autopsied at the time of euthanasia which is performed 24 hours after ultrasonography, and above mentioned organs were measured actually. In ultrasonography of cynomolgus monkey, the gall bladder was 17.5 cm long, and 6.6 cm wide. The width of spleen was 8.8 mm. The right kidney was 35.5 mm long, 23.7 mm wide, and 15.2 mm deep. The ultrasonographic measurements of the left kidney in calves was similar. The urinary bladder was 27.7 mm long, and 20.5 mm wide.

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Ultrasonography of Abdominal Organs in Common Marmoset (Callithrix jacchus) (Common Marmoset(Callithrix jacchus)에서의 복부 초음파에 관한 연구)

  • 김명철;이재일;이수진;김남중;현병화;최양규;이철호
    • Journal of Veterinary Clinics
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    • v.18 no.4
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    • pp.354-357
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    • 2001
  • The purpose of this study is to construct fundamental information about the ultrasonographic diagnosis for extrinsic and intrinsic abdominal disease. Normal ultrasonography of liver, gall bladder, spleen, kidney, urinary bladder, stomach, pylorus, duodenum, and heart of 5 common marmoset(Callithrix jacchus) were determined by use of ultrasonography. One common marmoset was autopsied at the time of euthanasia which is performed 24 hours after ultrasonography, and above mentioned organs were measured actually. In ultrasonography of common marmoset, the gall bladder was 8.2 cm long, and 3.4 cm wide. The width of spleen was 4.3 mm. The right kidney was 22.2 mm long, 16.1 mm wide, and 9.3 deep. The ultrasonographic measurements of the left kidney in calves was similar. The urinary bladder was 8.6 mm long, and 5.0 mm wide.

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Polycystic kidney disease and therapeutic approaches

  • Park, Eun-Young;Woo, Yu-Mi;Park, Jong-Hoon
    • BMB Reports
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    • v.44 no.6
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    • pp.359-368
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    • 2011
  • Polycystic kidney disease (PKD) is a common genetic disorder in which extensive epithelial-lined cysts develop in the kidneys. In previous studies, abnormalities of polycystin protein and its interacting proteins, as well as primary cilia, have been suggested to play critical roles in the development of renal cysts. However, although several therapeutic targets for PKD have been suggested, no early diagnosis or effective treatments are currently available. Current developments are active for treatment of PKD including inhibitors or antagonists of PPAR-${\gamma}$, TNF-${\alpha}$, CDK and VEGF. These drugs are potential therapeutic targets in PKD, and need to be determined about pathological functions in human PKD. It has recently been reported that the alteration of epigenetic regulation, as well as gene mutations, may affect the pathogenesis of PKD. In this review, we will discuss recent approaches to PKD therapy. It provides important information regarding potential targets for PKD.

Preferences of ICT among Patients with Chronic Kidney Disease Undergoing Hemodialysis: An Ecuadorian Cross-Sectional Study

  • Cherrez-Ojeda, Ivan;Felix, Miguel;Mata, Valeria L.;Vanegas, Emanuel;Gavilanes, Antonio W.D.;Chedraui, Peter;Simancas-Racines, Daniel;Calderon, Juan Carlos;Ortiz, Fabian;Blum, Guillermina;Plua, Angela;Gonzalez, Gino;Moscoso, Grace;Morquecho, Walter
    • Healthcare Informatics Research
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    • v.24 no.4
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    • pp.292-299
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    • 2018
  • Objectives: The aim of the present study was to assess the frequency of use, and preferences regarding information and communication technologies (ICTs) among Ecuadorian patients with chronic kidney disease (CKD) undergoing hemodialysis. Methods: We conducted an anonymous cross-sectional survey-based study from January 2016 to April 2017, involving 393 patients with end-stage renal disease from 9 hemodialysis centers, in which they rated their use and preferences of various ICTs through a modified version of the Michigan Questionnaire. The questionnaire collected information regarding demographics, patients' interest in obtaining health-related information through ICTs, and interest in using ICTs as a potential way to communicate with their healthcare providers. A chi-square test for association and adjusted regression analyses were performed. Results: Among all patients who participated, 64.3% reported owning a cellphone, with less than a third reporting active Internet connection. The most used ICT for obtaining information about CKD and/or hemodialysis was web-based Internet, followed by YouTube. SMS was rated the highest to receive and seek health-related information, followed by Facebook. Younger age and higher levels of education were associated with a higher overall usage of ICTs. Finally, more than half of the patients reported interest in using WhatsApp for communicating with their healthcare providers. Conclusions: Understanding the preferences of ICTs among patients with CKD undergoing hemodialysis could help to improve their outcomes through the potential uses and benefits of ICTs. Further research is needed to assess their role in improving the care of patients with chronic diseases.

The Influence of Hemosialysis to the Face Color of Patients in End Stage Renal Disease (말기신부전 환자의 혈액투석 치료가 안면 색에 미치는 영향)

  • Lee, Se-Hwan;Cho, Dong-Uk
    • The KIPS Transactions:PartB
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    • v.17B no.6
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    • pp.437-444
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    • 2010
  • In this paper, we propose a method of analysing the relation between the patient's face color and his(her) kidney disease using image processing technology. This method is based on the ocular inspection which is one of the most famous diagnosis methods used in the oriental medical system. The way of processing and analysing the face image, which is for visualization and objectification of the color difference, is included. The objects are selected from the patients who suffer the kidney disease and use the hemodialyzer. Their facial images and clinical data are collected. From these data, we propose a hypothesis that the color of the patient's face is changed according to the patient's kidney state. At the same time, we present two algorithms of extracting the specific part of face which can identify the state of the patient's kidney and tracing the history of the color's change. This proposed method is evaluated through the practical experiments and their analysis.

Tissue Distribution and Binding Proteins of Radionuclides in Bivalve, Gomphina melanaegis (민들조개(Gomphina melanaegis)에서 방사성 동위원소의 조직내 분포와 결합단백질에 관한 연구)

  • Yoo, Byung-Sun;Chung, Hai-Won;Lee, Jeong-Ho
    • Journal of Radiation Protection and Research
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    • v.10 no.2
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    • pp.109-112
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    • 1985
  • Radioisotope tracer experiments on the distribution and the binding of radionuclides to proteins in bivalve were carried out in order to gain further information on biochemical behavior of radionuclides in marine bivalve, Gomphina melanaegis. The radioactivities (cpm/g) of $^{65}Zn\;and\;^{54}Mn$ after 7 days exposure were highly concentrated in liver and kidney in comparison to soft parts. The gel filtration profile of $^{65}Zn$ in liver and kidney showed three elution peaks, while $^{54}Mn$ showed two peaks in liver and three peaks in kidney. On the gel filtration of $^{137}Cs$ in liver and kidney, most of $^{137}Cs$ were eluted on one peak. Thus, it was considered that each radionuclide was bound to different proteins in liver and kidney of bivalve.

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The Effect of Theophylline on Improvement of Renal Function in Asphyxiated Neonates: A Systematic Review and Meta-analysis (주산기 가사가 있는 신생아에서 theophylline의 신기능 개선 효과에 대한 체계적 문헌고찰 및 메타분석)

  • Lee, Joo Won;Lee, So Yeon;An, Sook Hee
    • Korean Journal of Clinical Pharmacy
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    • v.29 no.2
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    • pp.115-124
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    • 2019
  • The purpose of this systematic review and meta-analysis was to assess the preventive effect of theophylline on acute kidney injury and the ameliorative effect of theophylline on renal function in asphyxiated neonates. A literature search of the PubMed/Medline, Embase, and Cochrane Library databases for information published up to February 2019 was conducted. All studies that reported the incidence rate of acute kidney injury, serum creatinine level, and glomerular filtration rate after the randomized administration of theophylline or placebo were included. In total, eight studies involving 498 neonates were eligible. The incidence rate of acute kidney injury was significantly lower in the theophylline group than in the placebo group (risk ratio [RR]: 0.42, 95% confidence interval [CI]: 0.32-0.55, p < 0.001). The changes in serum creatinine level in the theophylline group were significantly higher than those in the placebo group from the first day of life to 3 and 5 days of age (weighted mean difference [WMD]: -0.51, 95% CI: -0.62 to -0.40, p < 0.001, and WMD: -0.26, 95% CI: -0.34 to -0.18, p < 0.001, respectively). The changes in glomerular filtration rate in the theophylline group were significantly higher than those in the placebo group from the first day of life to 3 days of age and the last day of follow-up (WMD: 12.30, 95% CI: 9.39-15.21, p < 0.001, and WMD: 9.35, 95% CI: 6.43-12.27, p < 0.001, respectively). These results suggested that theophylline has a beneficial effect on the prevention of acute kidney injury in neonates with perinatal asphyxia.

Changes in Oxalate and Phytate Concentrations During Soymilk Processing from the Seeds of Korean Soybean Cultivars

  • Jang, Keum-Il;Yoon, Gun-Mook;Kim, Hong-Sig
    • Food Science and Biotechnology
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    • v.17 no.5
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    • pp.1122-1127
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    • 2008
  • A high dietary oxalate intake may lead to calcium oxalate (CaOx) kidney stones in the gastrointestinal tract. Most soy foods contain high concentrations of oxalate and/or phytate. This study analyzed the changes in oxalate (Ox), phytate ($InsP_6$), and calcium (Ca) during soymilk processing from the seeds of Korean recommended soybean cultivars (cvs). The contents of Ox, $InsP_6$, and Ca in 21 cvs ranged from 14, 108, and 148 to 231, 279, and 246 mg/100 g of dry seed, respectively. Seven cultivars were selected from the 21 cvs by the distributions of Ox, $InsP_6$, and Ca. Then, each contents of soymilk prepared from the 7 cvs were determined. All contents were lower in soymilk than in seeds, but the Ox to $InsP_6$ ratios changed from varying ratios (0.1-0.8) to normal ratios (0.8-1.0) in all cvs except 'Paldalkong'. Consequently, during soymilk processing, the Ox content was decreased and the $InsP_6$ content was remained higher than the Ox content although the Ox was likely to be less reductive than the $InsP_6$. These results may provide better information for minimizing the risk of formation of Ox kidney stones due to consumption of soy products.

Analysis on Eating Behavior and Nutritional Status of Nephritic Patients with Mild Kidney Malfunction in Korea (신장염 환자의 식행동 및 영양상태 평가)

  • 김종연;오세영;임천규
    • Journal of Nutrition and Health
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    • v.34 no.7
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    • pp.770-777
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    • 2001
  • This study investigated nutritional status and eating behaviors among 59 nephritic patients with mild kidney malfunction in Korea. Nutritional status was measured by blood analysis and 1-3 day dietary recall and records, and eating behaviors were assessed by a questionnaire. Mean Body Mass Index(BMI) was within the normal range, while 21% and 14% of the patients were underweight and overweight, respectively. They received nutrition information mainly from doctors, nurses and mass media, but rarely from nutrition professionals. A quarter of patients skipped breakfast at least 3 times per 12% of the patients, respectively. Energy intake of 83% of the patients was less than the recommended level. Protein intakes of 56% of them were either under or over the recommended levels. Patients had low vitamin B$_2$ and calcium(<75% of the RDA) and excessive phosphorus(138% RDA) and vitamin C(170% RDA). Major food sources to absolute nutrient intakes were similar to those for the average Koreas, except for milk. Milk intake was low in our patients. Dietary quantity and quality were associated positively with BMI, albumin, and HDL-cholesterol and negatively with triglycerides and BUN. Results of this study indicate low nutritional status of the patients and, in turn a need for conducting nutritional education or counselling at regular at regular basis for the nephritic patients with mild kidney malfunction.

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Proteomics for monitoring of chicken responses to immune system in Korean Native Chickens

  • Park, Kang-Duk;Park, Sun-Young;Kim, Sung-Do;Suh, Guk-Hyun;Jang, Byoung-Gui;Sang, Byung-Bon;Lee, Jun-Heon
    • Proceedings of the Korea Society of Poultry Science Conference
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    • 2003.11a
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    • pp.138-139
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    • 2003
  • Specific biomarkers to detect significant immunological or physiological responses would be extremely valuable on the development of feeding technique. Proteomics, the study of proteins within a cell or biological samples, may offer a novel approach to immunological or physiological monitoring of chicken responses to immune system. By studying the protein content of cells responding to a vaccine or growth factor, it may be possible to develop a metric for quantitating the magnitude of immunological or physiological responses. Proteomics could also provide a tool for obtaining valuable information regarding the underlying regulatory mechanisms and pathways in Korean Native Chicken by comparing with subspecies of KNC and other species, like Cornish and White Leghorns.

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