Proceedings of the Korea Society of Poultry Science Conference (한국가금학회:학술대회논문집)
- 2003.11a
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- Pages.138-139
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- 2003
Proteomics for monitoring of chicken responses to immune system in Korean Native Chickens
- Park, Kang-Duk (East West Kidney Disease Research Institute, School of Medicine, Kyung Hee University) ;
- Park, Sun-Young (East West Kidney Disease Research Institute, School of Medicine, Kyung Hee University) ;
-
Kim, Sung-Do
(East West Kidney Disease Research Institute, School of Medicine, Kyung Hee University)
;
- Suh, Guk-Hyun (National Livestock Research institute, RDA) ;
- Jang, Byoung-Gui (National Livestock Research institute, RDA) ;
- Sang, Byung-Bon (National Livestock Research institute, RDA) ;
-
Lee, Jun-Heon
(Chungnam National University)
- Published : 2003.11.01
Abstract
Specific biomarkers to detect significant immunological or physiological responses would be extremely valuable on the development of feeding technique. Proteomics, the study of proteins within a cell or biological samples, may offer a novel approach to immunological or physiological monitoring of chicken responses to immune system. By studying the protein content of cells responding to a vaccine or growth factor, it may be possible to develop a metric for quantitating the magnitude of immunological or physiological responses. Proteomics could also provide a tool for obtaining valuable information regarding the underlying regulatory mechanisms and pathways in Korean Native Chicken by comparing with subspecies of KNC and other species, like Cornish and White Leghorns.
본 연구는 proteomics의 방법을 이용하여 가금의 면역시스템에 관련된 단백질을 찾고자 수행하였다. 면역활성 물질을 처리한 후 면역활성화시 발현되는 단백질을 찾아보았다. 이 결과는 가금의 면역과 관련된 단백질 마커의 이용뿐 아니라 현재까지 밝혀지지 않은 가금의 2D map을 만드는데 역시 중요하게 이용이 될 것이다.
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