• 제목/요약/키워드: Key Risk Factors

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Risk Factors of Hepatocellular Carcinoma - Current Status and Perspectives

  • Gao, Jing;Xie, Li;Yang, Wan-Shui;Zhang, Wei;Gao, Shan;Wang, Jing;Xiang, Yong-Bing
    • Asian Pacific Journal of Cancer Prevention
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    • 제13권3호
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    • pp.743-752
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    • 2012
  • Hepatocellular carcinoma is a common disorder worldwide which ranks 5th and 7th most common cancer among men and women. In recent years, different incidence trends have been observed in various regions, but the reasons are not completely understood. However, due to the great public efforts in HCC prevention and alternation of lifestyle, the roles of some well documented risk factors played in hepatocarcinogenesis might have changed. This paper summarizes both the environmental and host related risk factors of hepatocellular carcinoma including well established risk factors such as hepatitis virus infection, aflatoxin and alcohol, as well as possible risk factors such as coffee drinking and other dietary agents.

동승석 에어백 핵심 성능 인자 및 상해위험도 예측 기법 개발에 대한 연구 (A Study on the Key Performance Factors of Passenger Airbag and Injury Risk Prediction Technique Development)

  • 박동규
    • 한국자동차공학회논문집
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    • 제21권5호
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    • pp.130-135
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    • 2013
  • Until now, passenger airbag design is based on the referred car design and many repetitive crash tests have been done to meet the crash performance. In this paper, it was suggested a new design process of passenger airbag. First, key performance factors were determined by analyzing the injury risk effectiveness of each performance factor. And it was made a relationship between injury risk and performance factor by using the response surface model. By using this one, it can be predicted the injury risk of head and neck. Predicted injury risk of optimal design was obtained through this injury risk prediction model and it was verified by FE analysis result within 18% error of head and 9% error of neck. It was shown that a target crash performance can be met by controlling the key performance factors only.

Risk Factors for Early and Late Intrahepatic Recurrence in Patients with Single Hepatocellular Carcinoma Without Macrovascular Invasion after Curative Resection

  • Li, Shu-Hong;Guo, Zhi-Xing;Xiao, Cheng-Zuo;Wei, Wei;Shi, Ming;Chen, Zhi-Yuan;Cai, Mu-Yan;Zheng, Lie;Guo, Rong-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • 제14권8호
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    • pp.4759-4763
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    • 2013
  • Background: Prognostic factors of postoperative early and late recurrence in patients with hepatocellular carcinoma (HCC) undergoing curative resection remain to be clarified. The aim of this study was to identify risk factors for postoperative early (${\leq}$ 2 year) and late (> 2 year) intrahepatic recurrences in patients with single HCCs without macrovascular invasion. Methods: A total of 280 patients from December 2004 to December 2007 were retrospectively included in this study. Intrahepatic recurrence was classified into early (${\leq}$ 2 year) and late (> 2 year) and the Chi-Square test or Fisher's exact test and multivariate logistic regression analysis were performed to determine significant risk factors. Results: During the follow-up, 124 patients had intrahepatic recurrence, early and late in 82 and 42 patients, respectively. Multivariate logistic regression analysis showed that microvascular invasion (p=0.006, HR: 2.397, 95% CI: 1.290-4.451) was the only independent risk factor for early recurrence, while being female (p = 0.031, HR: 0.326, 95% CI: 0.118-0.901), and having a high degree of cirrhosis (P=0.001, HR: 2.483, 95% CI: 1.417-4.349) were independent risk factors for late recurrence. Conclusions: Early and late recurrence of HCC is linked to different risk factors in patients with single HCC without macrovascular invasion. This results suggested different emphases of strategies for prevent of recurrence after curative resection, more active intervention including adjuvant therapy, anti-cirrhosis drugs and careful follow-up being necessary for patients with relevant risk factors.

건축공사 주요 재해 위험요소 도출 (Selecting Key Accident Risk Factors in Building Construction Projects)

  • 안성훈;류호원;박미송
    • 한국건축시공학회지
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    • 제11권1호
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    • pp.45-50
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    • 2011
  • 건축공사는 매우 다양한 위험요소를 내재하고 있기 때문에 항상 재해에 노출되어 있는 실정이다. 따라서 지금까지 건축공사에서 재생 발생을 감소시키기 위해서 많은 연구와 노력이 진행되었다. 하지만 지금까지의 연구는 주로 재해 발생원인 중 작업방법이 나 시설물과 같이 기술적인 요소에 대한 재해 방지대책에 관해서 주로 연구가 이루어졌다. 따라서 본 연구에서는 건축공사에서 기술적, 교육적, 규제적 요인을 모두 포함한 재해 위험요소를 도출한 후, 이를 계층분석과정을 이용해서 정량적으로 평가하여 우선순위가 높은 주요 재해 위험요소를 도출하는 것을 목적으로 한다. 이렇게 주요 재해 위험요소가 제시되면 사전에 위험요소를 인지할 수 있으며, 이를 통해서 재해발생을 줄이는데 기여할 수 있을 것이다.

MODELLING OF THE RISKS FACED BY INDIAN CONSTRUCTION COMPANIES ASSESSING INTERNATIONAL OPPORTUNITIES

  • M.N. Devaya;N.K. Jha
    • 국제학술발표논문집
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    • The 2th International Conference on Construction Engineering and Project Management
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    • pp.140-149
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    • 2007
  • Indian construction companies have only 0.05% market share in the 3-4 trillion dollar global construction business and only two Indian construction companies figure in the ENR "Top 225 Global Contractors 2006" list. Hence, while enormous scope for growth exists, international construction experience is limited. This study explores the risks as perceived by Indian companies venturing abroad since risks in international construction differ from home market risks. Literature survey identified a number of risk factors that were evaluated by the experts, highlighting fourteen important risk factors. Interpretive Structural Modelling (ISM) was used to develop a hierarchical model showing the relationships between the different risk factors, thus helping to focus on the key risks for effective risk management. The study shows that poor project management is a key risk forming the hub of the system, while political instability has maximum influence. The results of the study can be used by managers to visualise the risks in perspective and prioritise the mitigation effort.

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군용 비행장에서 청력손실의 위험요소 분석 (Risk Analysis of Hearing Loss in the Air Base)

  • 김선경;이승현;김동수
    • 한국군사과학기술학회지
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    • 제15권2호
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    • pp.186-192
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    • 2012
  • Noise is a major cause of hearing loss in the air base. There are lots of risk factors of hearing loss including noise, and hearing loss can be accelerated by combined effects of these risk factors. Here in, we reviewed risk factors of hearing loss, and analysed key risk factors inducing hearing loss in the air base. Risk factors exacerbating hearing loss with noise were mainly investigated in this research because noise could not be an avoidable risk factor in the air base. Analysed data will contribute to make green environment minimizing hearing loss of pilots and supporting personnels in the air base.

Prognostic Model Built on Blood-based Biomarkers in Patients with Metastatic Colorectal Cancer

  • He, Wen-Zhuo;Jiang, Chang;Yin, Chen-Xi;Guo, Gui-Fang;Rong, Ru-Ming;Qiu, Hui-Juan;Chen, Xu-Xian;Zhang, Bei;Xia, Liang-Ping
    • Asian Pacific Journal of Cancer Prevention
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    • 제15권17호
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    • pp.7327-7331
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    • 2014
  • Background: We had previously showed that the neutrophil lymphocyte ratio (NLR), ${\gamma}$-glutamyl transpeptidase (GGT) and carcinoembryonic antigen (CEA) are prognostic factors for metastatic colorectal cancer (mCRC) patients. In this study we developed a prognostic model based on these three indices. Materials and Methods: A total of 243 patients who were initially diagnosed as mCRC between 2005 and 2010 in the Sun Yat-sen University Cancer Center were studied. The endpoint was overall survival (OS). Results: NLR>3, elevated GGT and elevated CEA were confirmed as independent risk factors which could predict poor prognosis. Patients could be divided into three groups according to the number of risk factors they had. Those with two or three were defined as the high risk group, individuals with one risk factor as the modest risk group and patients without risk factor as the low risk group. The OS values for these three groups were 16.2 months (2.80~68.8), 24.2 months (4.07~79.0), and 37.2 months (12.6~87.8), respectively (p<0.001). Conclusions: We developed a simple but useful model based on NLR, GGT and CEA to provide prognostic information to clinical practice in highly selected mCRC patients. Further prospective and multi-center studies are warranted to test our model.

해양사고의 새로운 위기요소 식별에 관한 기초 연구 (Research on the Unidentified Risk Factors of Maritime Accidents)

  • 양시일;정재용;임정빈
    • 한국항해항만학회:학술대회논문집
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    • 한국항해항만학회 2015년도 춘계학술대회
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    • pp.236-238
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    • 2015
  • 해상환경 변화와 과학기술 발전 등에 따라 기존에 알지 못하던 미식별 위기가 새롭게 창출되고 있다. 새로운 위기는 새로운 해양사고를 야기하기 때문에 이를 조기에 인지하지 못하면 해양사고는 지속 발생할 수밖에 없다. 따라서 미 식별된 또는 새로운 위기요소의 식별은 해양사고 예방에 중요하다. 그리고 많은 나라에서 다양한 해양사고 분석 기법과 모델들을 사용하여 해양사고를 줄이기 위해 노력하고 있는데, 해양사고 모델 개발을 위해서는 앞으로 발생할 수 있는 위기요소들에 대한 식별 및 분류도 필요하다. 이 연구에서는 기존의 식별된 위기요소와 새로운 위기요소 식별에 관하여 기초 조사하였다.

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발생영역별 리스크 위계에 따른 투자개발형 해외건설사업의 핵심 리스크 인자 도출 및 평가 (Evaluating and Suggesting Key Risk Factors according to Risk Hierarchy of Occurrence Field in the Overseas Development Projects)

  • 이정석;안병주;김재준
    • 한국건설관리학회논문집
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    • 제13권2호
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    • pp.70-79
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    • 2012
  • 정부는 최근 장기적인 관점에서 해외건설사업의 시장 활성화와 수주 경쟁력 강화에 주력하고 있다. 또한 중동 지방의 플랜트 프로젝트에 집중되어 있는 해외건설시장의 다각화를 추진하기 위하여 투자개발형 사업을 확대하기로 하였다. 하지만 현재까지 투자개발형 사업에 대한 리스크 분석 사례는 미미한 실정이다. 이에 본 연구에서는 투자개발형 해외건설사업들에 대한 리스크 분석의 필요성을 제기하고자 한다. 본 연구의 목적은 해외 투자개발형 사업에 대해서 AHP 및 퍼지이론을 적용하여 핵심 리스크 인자를 도출하기 위한 한 가지 방법론을 제시하는 것이다. 본 연구의 결과로써, 총 37개의 최종 핵심 리스크 인자들이 선정되었고, 이것들에 대한 특성을 분석하였다. 향후 연구에서는 본 연구의 결과를 토대로 해외 투자개발형 사업을 위한 리스크 관리 모델을 제안하고, 이것의 타당성을 검증할 예정이다.

국내기업 IT 아웃소싱 수행의사에 영향을 미치는 위험요인에 관한 연구 (A Descriptive Study of IT Outsourcing Risk Factors in the Korean Company)

  • 문송철
    • 한국IT서비스학회:학술대회논문집
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    • 한국IT서비스학회 2009년도 춘계학술대회
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    • pp.287-292
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    • 2009
  • The Outsourcing Industry has grown swift pace and evolved over time, and the Global IT Outsourcing market has shown signs of a steady growth. In the Korean company, however, IT Outsourcing is not active as that of the advanced countries and there is lack of literature to understand the characterristics of IT Outsourcing in the Korean company. This paper, therefore, analyze the outcomes surveying 65 compaanies in Korea to investigate how IT Outsourcing risk factors affects IT Outsourcing intention. Based on our literature reviews bassed on number of key articles, journals, and the focus group interviews, IT Outsourcing risk factors are proposed into four different domains: Transaction, Client, Vendor, Environment perspectives. It found that one factor(Vendor perspectives) is closely related to the IT Outsourcing intention of the Korean company. Finally, this paper analyzed the pros and cons of IT Outrcing offers a guide to the risk factors.

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