• Title/Summary/Keyword: Joint development

Search Result 1,980, Processing Time 0.028 seconds

Financial Development, Business Cycle and Bank Risk in Southeast Asian Countries

  • TRAN, Son Hung;NGUYEN, Liem Thanh
    • The Journal of Asian Finance, Economics and Business
    • /
    • v.7 no.3
    • /
    • pp.127-135
    • /
    • 2020
  • The paper aims to examine whether business cycles affect the link between financial development and bank risk, measured by Zscore and non-performing loans to total loans in six Southeast Asian countries, namely Indonesia, Philippines, Malaysia, Singapore, Thailand and Vietnam. This study uses a sample of 95 listed commercial banks over a 15-year period between 2004 and 2018 in the six Southeast Asian countries. This study employs panel OLS regression and modifications to tackle issues such as endogeneity and heteroscedasticity. The results show that the impact of stock market development (the ratio of the market capitalization to GDP) on Zscore is significantly positive, whereas its effect on non-performing loans is significantly negative. The findings suggest that financial development, in terms of stock market capitalization, improves banks' Zscores and reduces their level of non-performing loans, suggesting that financial development on average reduces bank risk. The impact of business cycle is insignificant towards bank risk, thus rejecting both counter- and pro-cyclical hypotheses, except for the case of risk indicator of loan loss provisions. Examining the joint effect of the business cycle and financial development on bank risk, we find that the phase of business cycles generally does not moderate the link between financial development and bank risk.

Associations Between TLR9 Polymorphisms and Cancer Risk: Evidence from an Updated Meta-analysis of 25,685 Subjects

  • Wan, Guo-Xing;Cao, Yu-Wen;Li, Wen-Qin;Li, Yu-Cong;Zhang, Wen-Jie;Li, Feng
    • Asian Pacific Journal of Cancer Prevention
    • /
    • v.15 no.19
    • /
    • pp.8279-8285
    • /
    • 2014
  • A meta-analysis incorporating 34 case-control studies from 19 articles involving 12,197 cases and 13,488 controls was conducted to assess the effects of three genetic variants of Toll-like receptor 9 (TLR9): rs187084, rs352140, and rs5743836. Studies on associations between TLR9 polymorphisms and cancer risk were systematically searched in electronic databases. The reported odds ratios (OR) and 95% confidence intervals (CI) were pooled to assess the strength of any associations. The results showed that the rs187084 polymorphism was significantly associated with an increased risk of cancer (CC vs TC+TT: OR=1.14, 95% CI=1.02-1.28), specifically cervical cancer (C vs T: OR=1.19, 95% CI=1.05-1.34; TC vs TT: OR=1.32, 95% CI=1.10-1.58; CC vs TT: OR=1.31, 95% CI=1.03-1.68; CC+TC vs TT: OR=1.32, 95% CI=1.11-1.56), and that this association was significantly positive in Caucasians (CC vs. TC+TT: OR=1.18, 95% CI=1.01-1.38). The rs352140 polymorphism had a protective effect on breast cancer (GA vs GG: OR=0.77, 95% CI=0.66-0.89), whereas the rs5743836 polymorphism was likely protective for digestive system cancers (CC+TC vs TT: OR=0.81, 95% CI=0.66-0.98). In conclusion, our results suggest that the rs187084 polymorphism may be associated with an elevated cancer risk, whereas polymorphisms of rs352140 and rs5743836 may play protective roles in the development of breast and digestive system cancers, respectively. From the results of this meta-analysis further large-scale case-control studies are warranted to verify associations between TLR9 polymorphisms and cancer.

Antifouling Activity towards Mussel by Small-Molecule Compounds from a Strain of Vibrio alginolyticus Bacterium Associated with Sea Anemone Haliplanella sp.

  • Wang, Xiang;Huang, Yanqiu;Sheng, Yanqing;Su, Pei;Qiu, Yan;Ke, Caihuan;Feng, Danqing
    • Journal of Microbiology and Biotechnology
    • /
    • v.27 no.3
    • /
    • pp.460-470
    • /
    • 2017
  • Mussels are major fouling organisms causing serious technical and economic problems. In this study, antifouling activity towards mussel was found in three compounds isolated from a marine bacterium associated with the sea anemone Haliplanella sp. This bacterial strain, called PE2, was identified as Vibrio alginolyticus using morphology, biochemical tests, and phylogenetic analysis based on sequences of 16S rRNA and four housekeeping genes (rpoD, gyrB, rctB, and toxR). Three small-molecule compounds (indole, 3-formylindole, and cyclo (Pro-Leu)) were purified from the ethyl acetate extract of V. alginolyticus PE2 using column chromatography techniques. They all significantly inhibited byssal thread production of the green mussel Perna viridis, with $EC_{50}$ values of $24.45{\mu}g/ml$ for indole, $50.07{\mu}g/ml$ for 3-formylindole, and $49.24{\mu}g/ml$ for cyclo (Pro-Leu). Previous research on the antifouling activity of metabolites from marine bacteria towards mussels is scarce. Indole, 3-formylindole and cyclo (Pro-Leu) also exhibited antifouling activity against settlement of the barnacle Balanus albicostatus ($EC_{50}$ values of 8.84, 0.43, and $11.35{\mu}g/ml$, respectively) and the marine bacterium Pseudomonas sp. ($EC_{50}$ values of 42.68, 69.68, and $39.05{\mu}g/ml$, respectively). These results suggested that the three compounds are potentially useful for environmentally friendly mussel control and/or the development of new antifouling additives that are effective against several biofoulers.

REAL-TIME QUALITY EVALUATION OF FRICTION WELDING OF MACHINE COMPONENTS BY ACOUSTIC EMISSION (음향방출법(AE)에 의한 기계요소재의 마찰용접 품질 실시간 평가)

  • SAE-KYOO OH
    • Proceedings of the KWS Conference
    • /
    • 1995.10a
    • /
    • pp.3-20
    • /
    • 1995
  • Development of Real-Time Quality Evaluation of Friction Welding by Acousitc Emission : Report 1 ABSTRACT : According as the friction welding has been increasingly applied in manufacturing various machine components because of its significant economic and technical advantages, one of the important concerns is the reliable quality monitoring method for a good weld quality with both joint strength and toughness in the process of its production. However no reliable nondestructive test method is available at present to determine the weld quality particularly in process of production. So this paper presents an experimental examination and quantitative analysis for the real-time evaluation of friction weld quality by acoustic emission, as a new approach which attempts finally to develop an on-line quality monitoring system design for friction welds using AE techniques. As one of the important results, it was confirmed, through this study, that AE techniques can be reliably applied to evaluating the friction weld qualify with 100% joint strength, as the cumulative AE counts occurring during welding period were quantitatively correlated with reliability at 95% confidence level to the joint strength of welds. Real-Time Evaluation of Automatic Production Quality Control for Friction Welding Machine : Report 2 Abstract : Both in-process quality control and high reliability of the weld is one of the major concerns in applying friction welding to the economical and qualified mass-production. No reliable nondestructive monitoring method is available at present to determine the real-time evaluation of automatic production quality control for friction welding machine. This paper, so that, presents the experimental examinations and statistical quantitative analysis of the correlation between the initial cumulative counts of acoustic emission(AE) occurring during plastic deformation period of the welding and the tensile strength of the welded joints as well as the various welding variables, as a new approach which attempts finally to develop an on-line (or real-time) quality monitoring system and a program for the process of real-time friction welding quality evaluation by initial AE cumulative counts. As one of the important results, it was well confirmed that the initial AE cumulative counts were quantitatively and cubically correlated with reliability of 95% confidence level to the joint strength of the welds, bar-to-bar (SCM4 to SUM31, SCM4 to SUM24L) and that an AE technique using initial AE counts can be reliably applied to real-time strength evaluation of the welded joints, and that such a program of the system was well developed resulting in practical possibility of real-time quality control more than 100% joint efficiency showing good weld with no micro-structural defects.

  • PDF

Differential Response to Joint Attention in Children with Autism Spectrum Disorder Depending on the Level of Attentional Cues (주의 단서 수준에 따른 자폐 범주성 장애 아동의 공동주의집중 반응 연구)

  • Yoo, Ga Eul
    • Journal of Music and Human Behavior
    • /
    • v.11 no.1
    • /
    • pp.21-37
    • /
    • 2014
  • The significant role of joint attention in the development of children with autism spectrum disorder (ASD) has highlighted the importance of early intervention. With the emphasis on the effective cueing and reinforcer for orienting to social stimuli in improving responding to joint attention (RJA) of children with ASD, the use of musical cue was hypothesized. This study aimed to examine the occurrence of RJA behaviors depending on the attentional cue, which differed in the level of information and type of auditory modality. Nine children with ASD participated in this study. The use of eight different joint attention cues were analyzed in terms of the frequency and accuracy of RJA behaviors elicited. The results of the study showed that RJA behaviors occurred more frequently with musical cues than with verbal cues and the mean accuracy rate of RJA was higher with musical cues (p = .047). Musically delivered eliciting and directing cues accompanied with pointing elicited the highest attentional shift and RJA accuracy. The significant increases in RJA with the use of musical cues indicated that incorporating musical elements into an attentional cue may provide more accurate cue information, enough to improve RJA behaviors of children with autism.

An Analysis of the Effect of Density of the Joint Research Network between Countries on Technology Diffusion: focusing on the case of secondary battery and the electric vehicle field (국가 간 공동연구 네트워크 밀도가 기술 확산에 미치는 영향 분석: 이차전지, 전기자동차 분야 사례를 중심으로)

  • Jeong, Dae-Hyun;Kwon, Young-Il;Hong, Soon-Ki;Cho, Keuntae
    • The Journal of the Korea Contents Association
    • /
    • v.14 no.9
    • /
    • pp.582-588
    • /
    • 2014
  • The purpose of this study is to analyze how a joint research network between countries affects the diffusion of technology information and how much countries with high centrality on the network accept new technology and to seek their meaning. With this aim, the joint research network density between countries by year and the number of participating countries were measured using thesis information regarding the secondary battery field and the electric vehicle field, and a regression analysis of relevant variables was conducted. As a result of the analysis, the greater the joint research network density in the secondary battery field, the higher the number of participating countries in a linear relationship. Also, on the joint research network, countries with high degree centrality were discovered to have led development in the mid to large size secondary battery field. Meanwhile, for the electric vehicle field, although there appeared no increase in the network density value, the number of participating countries was found to have increased. This was analyzed that joint research between countries was not a necessary and sufficient condition although it played a crucial role in promoting technology diffusion. Such a result is meaningful in that it verified promoting factors for essential technology diffusion statistically; however, with this research, there exist limitations that the index of a central role on the network was measured only with degree centrality and that only the relationship between two players was measured for network density in interactions between players. Accordingly, it is necessary to carry out research into a method to measure interactions among multiple researchers in the future.

A Study on Standardization of Shinbaro Pharmacopuncture Using Herbal Medicines Identification Test and HPLC-DAD (신바로 약침의 한약재 확인시험 및 HPLC-DAD를 통한 표준화 연구)

  • Lee, Jin Ho;Kim, Min Jeong;Lee, Jae Woong;Kim, Me Riong;Lee, In Hee;Kim, Eun Jee
    • Journal of Acupuncture Research
    • /
    • v.32 no.2
    • /
    • pp.1-9
    • /
    • 2015
  • Objectives : The present study was an evaluation and standardization of herbal components in order to establish the efficacy and safety of Shinbaro pharmacopuncture. Methods : Among the raw materials of Shinbaro pharmacopuncture, the components Cibotii Rhizoma, Eucommiae Cortex, and Ledebouriellae Radix were assessed through ingredient verification experiments using thin-layer chromatography(TLC) and ultraviolet rays(UV) lamps. In addition, we standardized Acanthopanacis Cortex and Achyranthis Radix through validation using high performance liquid chromatograph-diode array detector(HPLC-DAD). Results : As result appeared a blue-white fluorescence under ultraviolet rays; changed to dark green after adding 1 % ferric chloride solution(due to Cibotii Rhizoma), and presented a yellow-green fluorescence when mixed with an ethyl ether under UV lamps by way of the ethyl ether layer, confirming Eucommiae Cortex. Ledebouriellae Radix was confirmed as dark brown spots at Rf values of 0.56 and 0.71 using TLC. Additionally, Acanthopanacis Cortex and Achyranthis Radix HPLC test results showed that linearity was $R^2{\geq}0.99$, and detection limit and quantitation limit were 0.23 to $1.29{\mu}g/mL$, and 0.71 to $3.90{\mu}g/mL$, respectively. Furthermore, precision and accuracy were confirmed to have relative standard deviation(RSD) values of 0.10 to 1.89 % and 96.19 to 103.72 %, respectively. Shinbaro pharmacopuncture did not have any overlapping or interference from other peaks in detection under the abovementioned analysis conditions. Conclusions : In conclusion, we confirmed that maintenance of Shinbaro pharmacopuncture validity was possible by means of quality control of Cibotii Rhizoma, Eucommiae Cortex, and Ledebouriellae Radix through ingredient identification and Acanthopanacis Cortex and Achyranthis Radix through high performance liquid chromatograph(HPLC) analysis. Further, we hope to contribute to the development strategy of herbal industry acupuncture.

Cause of Rockfall at Natural Monument Pohang Daljeon-ri Columnar Joint (천연기념물 포항 달전리 주상절리의 낙석 발생원인)

  • Kim, Jae Hwan;Kong, Dal-Yong
    • Economic and Environmental Geology
    • /
    • v.55 no.5
    • /
    • pp.497-510
    • /
    • 2022
  • Monthly monitoring, 3D scan survey, and electrical resistivity survey were conducted from January 2018 to August 2022 to identify the cause of rockfall occurring in Daljeon-ri Columnar Joint (Natural Monument No. 415), Pohang. A total of 3,231 rocks fell from the columnar joint over the past 5 years, and 1,521 (47%) of the falling rocks were below 20 cm in length, 978 (30.3%) of 20-30 cm, and 732 (22.7%) of rocks over 30 cm. While the number of rockfalls by year has decreased since 2018, the frequency of rockfalls bigger than 30 cm tends to increase. Large-scale rockfalls occurred mainly during the thawing season (March-April) and the rainy season (June-July), and the analysis of the relationship between cumulative rainfall and rockfall occurrence showed that cumulative rainfall for 3 to 4 days is also closely related to the occurrence of rockfall. Smectite and illite, which are expansible clay minerals, were observed in XRD analysis of the slope material (filling minerals) in the columnar joint, and the presence of a fault fracture zone was confirmed in the electrical resistivity survey. In addition, the confirmed fault fracture zone and the maximum erosion point analyzed through 3D precision measurement coincided with the main rockfall occurrence point observed by the BTC-6PXD camera. Therefore, the main cause of rockfall at Daljeon-ri columnar joint in Pohang is a combination of internal factors (development of fault fracture zones and joints, weathering of rocks, presence of expansive clay minerals) and external factors (precipitation, rapid thawing phenomenon), resulting in large-scale rockfall. Meanwhile, it was also confirmed that the Pohang-Gyeongju earthquake, which was continuously raised, was not the main cause.

A Study on the Reasons of Development Gap in Rural Community Development : The Application of Neo-Endogenous Development (농촌마을 발전 격차의 원인에 대한 연구: 신내생적 발전론의 적용)

  • Kim, Tae-Yeon
    • Korean Journal of Organic Agriculture
    • /
    • v.28 no.1
    • /
    • pp.69-93
    • /
    • 2020
  • The paper is to compare two villages in Songak-myeon, Asan, Cnungnam Province in Korea. It tries to show how the joint village project, which began with the support of the same external organization, produces different results depending on the internal conditions and circumstances of the village. From the end of the 1990s, Pyeongchon-ri and Sugok-ri started developing villages under the influence of the environmentally friendly farming movement. And subsequent supports were provided by local organizations for the development of the village. However, the village project in Sugok-ri, which focused on economic performance, later turned out to be a failure, and the residents changed to pursue activities for their own economic interests individually. On the other hand, In Pyeongchon-ri, the cooperation among villagers was strengthened in implementing support projects by similar external agencies. In addition, community ties and identity have been strengthened as problems have been solved through cooperation among residents in the process of promoting the village project. Nevertheless, projects undertaken in Pyeongchon-ri for the purpose of increasing economic performance was all failed. Through these findings, the paper asserts that the neo-endogenous development approach utilizing external support on the basis of internal cooperative network among villagers must be a very useful method for rural development in contemporary societies.

Self-Collision Detection/Avoidance for a Rescue Robot by Modified Skeleton Algorithm (보완 골격 알고리듬을 이용한 구난로봇의 자체 충돌감지/회피)

  • Lee, Wonsuk;Hong, Seongil;Park, Gyuhyun;Kang, Younsik
    • Journal of the Korea Institute of Military Science and Technology
    • /
    • v.18 no.4
    • /
    • pp.451-458
    • /
    • 2015
  • This paper handles self-collision avoidance for a rescue robot with redundant manipulators. In order to detect all available self-collisions in advance, minimum distances between arbitrary robot parts should be monitored in real-time. For the minimum distance estimation, we suggest a modified method from a previous skeleton algorithm which has less computation burden and realize collision avoidance based on a potential function using the proposed algorithm. The resultant command by collision avoidance should not disturb a given primary task, so null-space of joint solution from a CLIK is utilized for collision avoidance by a gradient projection method.