• Pediatric Infection and Vaccine
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• 제13권2호
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• pp.174-179
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• 2006

국내에서는 아직도 소아연령에서 결핵 감염이 적지 않게 존재하기 때문에 폐외 결핵 환자가 발생될 위험도 지속적으로 존재한다. 이런 측면에서 폐외 결핵의 하나인 골관절 결핵은 매우 드물기는 하나, 관절염을 주소로 내원한 환자의 원인으로 고려해 볼만하다. 나이 어린 소아에서는 증상과 징후가 비특이적이기 때문에 오진이나 진단 지연이 우려되므로, 항생제 치료에 잘 반응하지 않는 관절염 환자에서는 결핵성 골관절염에 대한 진단과 치료를 시도하는 것이 중요하다.

• 디지털융복합연구
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• 제19권2호
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• pp.307-314
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• 2021

본 연구는 척추·관절질환 환자 만족도와 병원 추천 의향을 분석하고 만족도에 영향을 미치는 요인을 확인하기 위해 수행되었다. 이에 2019년 서울지역 소재 척추·관절 전문병원에서 환자 만족도와 추천 의향을 조사하였고, 인구·사회적 특성과 환자 만족도와의 관련성, 만족도 영향요인 및 추천 의향 등을 분석하였다. 분석 결과 외래의 경우 직원 용모·복장의 단정함과 청결도, 직원 친절도, 시설환경 쾌적성에서 환자 만족도가 높게 나타났고, 대기시간 관련 문항에서 환자 만족도가 낮게 나타났다. 입원의 경우 간호 영역과 병원환경 영역에서 여성의 만족도가 높았다. 하위 영역별로는 간호 영역 중 고객 존중 및 예의, 고객 경청, 담당 간호사에서 환자 만족도가 높게 나타났고, 병원환경 영역은 전반적인 병원 청결도와 안전 문항에서 만족도가 높았다. 환자 만족도와 주변에 해당 병원을 추천할 의향이 있는지를 묻는 문항 간 상관관계 분석에서는 환자 만족도와 병원 추천 의향은 양의 상관관계가 있는 것으로 나타났다. 척추·관절 질환 환자 만족도와 추천 의향 평가 결과는 척추·관절 전문병원에서 의료서비스 질 향상과 병원경영 전략 수립을 위한 기초 자료로 활용될 수 있을 것이다.

• 대한방사선기술학회지:방사선기술과학
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• 제46권5호
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• pp.395-399
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• 2023

The knee arthritis patients are generally performed standing position radiography. However, patients with pain caused by degenerative diseases or injuries in the knee have difficulty maintaining a standing position. Therefore, this study aims to develop a knee joint standing weight bearing projection assist device to solve these problems when patients undergo knee radiography due to various diseases. The design of the knee joint weight-bearing radiography assist device is carried out with 3D design and drawing production to secure basic data, electric support and frame manufacture. A fixed device for maintaining the patient's knee standing weight-bearing projection, an electric digital height device, a digital protractor, and a safety device were designed. The arm support is made of PVC with a cushion to relieve the impact and make it easier to remove debris. The digital electric device can be moved up and down according to the patient's height, and a remote control is attached. The safety device is made to be adjustable in size by attaching metal hooks on both sides of the frame and to shield the scrotum. A digital protractor was attached to the side frame to set the desired knee angle. When a self-made assist device was used to perform a knee joint standing weight bearing projection, it helped maintain arm support and lower extremities position. In addition, the height could be adjusted using an assist device during standing projections, which helped the patient maintain the position.

• Journal of Korean Dental Science
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• 제15권2호
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• pp.101-111
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• 2022

The purpose of laboratory tests in the field of oral medicine can be divided into two categories: (1) medical evaluation of patients with systemic diseases that are planning to receive dental care and (2) diagnosis of patients with certain oral diseases. First, laboratory tests are commonly used to evaluate patients with systemic diseases who need dental management. A combination of multiple tests is usually prescribed as a test panel to diagnose and assess a specific disease. Test panels closely related to oral medicine include those for rheumatoid arthritis, connective tissue disease/lupus, liver function, thyroid screening, anemia, and bleeding disorders. Second, laboratory tests are used as auxiliary diagnostic methods for certain oral diseases. They often provide crucial diagnostic information for infectious diseases caused by bacteria, fungi, and viruses that are associated with pathology in the oral and maxillofacial regions. Laboratory tests for infectious diseases are composed of growth-dependent methods, immunologic assays, and molecular biology. As the field develops, further application of laboratory tests, including synovial fluid analysis in temporomandibular joint disorders, salivary diagnostics, and hematologic biomarkers associated with temporomandibular disorders and orofacial pain conditions, is currently under scrutiny for their reliability as diagnostic tools.

• 국제물리치료학회지
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• 제11권4호
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• pp.2191-2196
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• 2020

Background: Incorrect postures of adolescents caused by the use of smart devices have been noted as a factor causing spinal diseases. Objectives: To examine the effect of joint mobilization and stretching on Cobb's angle and respiratory function in adolescent idiopathic scoliosis (AIS). Design: Cluster-randomized controlled trial. Methods: A total of 22 subjects with AIS were enrolled. They were allocated to two groups: the joint mobilization (n=11) and the stretching (n=11). All interventions were conducted for 30 minutes, three times a week for six weeks. Outcome measures were the Cobb's angle and respiratory function. The Cobb's angle and respiratory function measured using the X-ray and Micro-Quark. Results: Joint mobilization group showed significant differences in Cobb's angle and respiratory function, but stretching group showed significant differences Cobb's angle. The differences in peak expiratory flow (PEF) between the two groups were significant. Conclusion: This study proved that joint mobilization is a more effective intervention for AIS to improve Cobb's angle and respiratory function, when compared to stretching.

• 대한의생명과학회지
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• 제29권4호
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• pp.220-230
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• 2023

Identification of the pathogens causing infection is important in terms of patient's health management and infection control. Synovial fluids could be used as clinical samples to detect causative pathogens of prosthetic joint infections (PJIs) using molecular diagnostic assays, therefore, normalization and validation of clinical samples are necessary. Microbial culture is considered the gold standard for all infections, including PJIs. Recently, molecular diagnostic methods have been developed to overcome the limitation of microbial culture. Therefore, guideline for validating clinical samples to provide reliable results of molecular diagnostic assays for infectious diseases is required in clinical field. The present study aimed to develop an accurate validating method of synovial fluid clinical samples using GAPDH gene as an internal control to perform the quantitative PCR TaqMan probe assay to detect pathogens causing PJIs.

• Advances in Traditional Medicine
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• 제5권4호
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• pp.251-261
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• 2005

Rheumatoid arthritis (RA) is an autoimmune/inflammatory disorder with a complex genetic component. RA is characterized by chronic inflammation of the synovial membrane in the joint, which leads to the progressive destruction of articular cartilage, ligament and bone. Several cytokines such as tumor necrosis $factor-{\alpha}\;TNF-{\alpha}\;and\;interleukin-1{\beta}\;(IL-1{\beta})$ and interleukin-6 (IL-6) have been implicated in the pathological mechanisms of synovial tissue proliferation, joint destruction and programmed cell death in rheumatoid joint. Genome wide screening of subjects suffering from autoimmune diseases especially arthritis revealed linkage to inflammatory molecules like $TNF-{\alpha},\;IL-1{\beta}$ and IL-6, inducible nitric oxide synthase (iNOS), cyclooxygenase-2 (COX-2), nuclear factor-kappaB $(NF-{\kappa}B)$ and human leucocyte antigen/major histocompatibility complex (HLA/MHC) locus. The status of the pharmacological mechanism of herbal drugs in the light of genome wide screening results has been discussed to reinforce the therapeutic potential and the pharmacological basis of the herbal drugs.

• 한국의학물리학회지:의학물리
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• 제19권4호
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• pp.269-275
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• 2008

슬관절 퇴행성 질환을 진단하기 위하여 자기공명영상(magnetic resonance imaging: MRI)이 많이 사용되지만 간혹 슬관절 병후 및 예후를 잘못 진단하는 경우가 종종 발생한다. 본 연구에서는 슬관절 질환의 진단에 도움을 주기 위하여 자화전이(magnetization transfer: MT) 영상법을 소개하고자 한다. 슬관절 환자 7명으로부터 스핀 에코(SE) T2 강조 영상(3,400-3,500/90-100 ms)과 슬관절 환자 7명으로부터 FSE T2 강조 영상(4,500-5,000/100-108 ms)과 또한 슬관절 환자 3명으로부터 gradient echo (GRE) T2 강조 영상들(9/4.56 ms, 50 flip angle, NEX 1)을 획득하였다. 6명의 슬관절 환자에서 지방 억제가능 T2 강조 STIR 펄스시퀀스(TR/TE=2894-3215 ms/70 ms, NEX 3, ETL 9)를 사용하였다. 지방 포화도에 있어서 위상감도 방법은 Larmor frequency 차이에 따른 위상 차이를 이용하므로, 각각의 픽셀에 대한 자화전이율(magnetization transfer ratio: MTR)의 측정은 포화된 영상과 포화되지 않은 영상의 비율에 따라 산출하였다. 따라서 각 입력된 영상들은 동차원성을 가지고, 시각적으로 신호강도 정도가 회색의 명암도만으로 평가될 수 있기 때문에 생리학적, 정량적 진단을 위하여 3차원 등방성 체적영상과 자기공명 삼원색을 매핑하였고 정량적 특정은 자화전이율 지도로서 표현하였다. 자화전이율 영상은 병변 부위에서 높은 대조도를 나타내어 환자의 병태를 추적하는데 도움을 주었고 정량화하였다. 자화전이율 영상들과 기존의 MRI 사이에 명암도 차이는 회색상으로 표현되며, 자화전이율 영상화의 효과에 대해 프로파일 그래프는 자화전이 펄스로 인하여 신호강도에 있어서 정량적 측정값이 상대적으로 감소하였다. 슬관절의 정확한 병리상태를 진단하기 위해 프로파일 그래프의 측정값을 영상과 함께 표현하였다. 본 연구에서 수행한 예비적 데이터들을 통하여 슬관절의 자화전이율 영상들이 매우 임상학적으로 유용함을 확인하였다. 자화전이율 영상에 대한 물리적 변화를 관찰함으로써 자화전이율 영상에 대한 물리적, 기술적 기반에 대한 더 많은 통찰력을 제공할 수 있다. 무릎 질환 환자의 자화전이율 영상들을 이용하여 매우 높은 대조도를 확보할 수 있으므로 슬관절 질환의 정밀 진단에 매우 도움을 줄 수 있다.

• 한국전문물리치료학회지
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• 제21권2호
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• pp.8-17
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• 2014

The purpose of this study was to examine the effects of hip joint mobilization (HJM) on walking ability, balance ability, and the joint range of motion in stroke patients to minimize the problems of the musculoskeletal system in patients with central nervous system diseases. All volunteers were randomly assigned to the HJM group ($n_1=14$) and the general neurodevelopment therapy (NDT) group ($n_2=16$). The HJM procedure involved applying Maitland mobilization techniques (distraction, lateral gliding, inferior gliding, and anterior gliding) by grade 3 to both hip joint. The mobilization process included mobilization and NDT for 15 min/day, 3 days a week for 4 weeks. The outcome measures were evaluated, including the hip joint passive range of motion (ROM) test and femur head anterior glide test (FHAG) using prone figure four test, dynamic and static balance abilities [timed up and go (TUG) test and center of pressure (COP) analysis], and walking ability [10-meter walking test (10MWT) and 6-min walking test (6MWT)]. Both the groups showed significant post-training differences in the hip joint ROM (FHAG and degree of hip extension) and 10MWT. The post-training improvements in the TUG test were significantly greater in patients of the HJM group than in the NDT group; however, there were no post-training improvements in COP in both groups. Patients in the HJM group showed post-training improvement in the 6MWT; however, statistically significant differences were not observed. Patients in the NDT group showed post-training improvements in the 6MWT. These results suggest that HJM improves hip joint ROM, dynamic balance ability, and walking speed in stroke patients. However, further studies are required to evaluate the long-term therapeutic efficacy of HJM in stroke patients.

• 근관절건강학회지
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• 제7권1호
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• pp.40-52
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• 2000

Recently with the development in computer technology and its communication system, many changes in medical informatics enable us to use various medical information regardless of time or place. There are many home pages on the web, which provide medical counseling and hospital information. On May 11th 1999, Korean Rheumatology Health Professions Society began its new service as a home page on the web with various rheumatologic health information, questioning/ answering, and so on. This study was undertaken to examine the content and the purpose of health counseling on the web. The data was collected from 173 questioners who visited questioning/ answering site in the KRHPS home page for May 11th, 1999 through November 10th, 1999. Most of the questioners consulted the health problems of their or their families. Over two thirds of them were already diagnosed medically. Rheumatoid arthritis was the most frequent one. Other diseases, such as, osteoarthritis, ankylosing spondylitis, Still's disease were also on the list. Most of the questioners wanted to know treatment strategies, to consult about their symptoms, and to make diagnosis. And many questioners wanted detailed explanations about their diseases or the informations regarding the hospital. These findings suggest that the health counseling on the web may be used to supplement the lack of direct medical interviews with doctors. It also is expected to guide the patients to the right direction.