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Floc Behaviors Due to Flocculation Process (응집현상에 의한 플럭의 거동 변화)

  • Son, Minwoo;Park, Byeoung Eun;Byun, Jisun
    • Proceedings of the Korea Water Resources Association Conference
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    • 2019.05a
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    • pp.253-253
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    • 2019
  • 유사의 이동은 하천, 해안 지역과 같은 수계에서 하상의 변동, 침식과 퇴적을 일으켜 지형적인 변화를 초래한다. 유사의 이동은 유사의 특성과 유체의 유수동역학적 특성에 의해 결정되며 유체특성 간의 복잡한 상호 작용에 의해 변화한다. 유사가 가지는 점착성은 유사의 특성에 큰 영향을 끼친다. 입자의 크기가 매우 작은 점착성 유사는 그 표면이 가지는 전자기적 점착력에 의해 주위의 1차 입자나 다른 작은 알갱이들이 서로 뭉치는 응집과 충돌에 의해 크기가 작아지는 파괴의 과정을 겪는다. 이 과정을 응집현상이라고 하며 응집현상을 통해 점착성 유사의 크기와 밀도, 침강속도는 계속해서 변화한다. 따라서 점착성 유사의 응집거동 고려한 유사 이동 연구는 필수적이다. 과거 연구의 많은 사례에서 유사의 크기와 농도는 비례 관계를 가지는 것이 일반적이라 알려져 있다. 그러나 실제 현장에서 측정한 결과 유사의 크기와 농도가 반비례 관계를 가지는 특이점이 발견되었다. 실측 연구에서 발견된 응집거동에 따른 유사의 특성의 특이한 변화를 설명하기 위해 1차원 연직 수치 모형(1DV)을 이용하여 수치 실험을 수행하였다. 모의 수행 시, 흐름 조건을 크기와 방향이 일정한 순방향흐름(Current)에 특정 주기와 진폭을 가지는 진동 흐름(Oscillatory Flow)을 추가하여 진행하였다. 플럭의 성장과 그에 따른 입자의 크기는 많은 현상에 영향을 받는다. 그 중 응집현상의 응집 과정과 파괴 과정 중 어떤 현상이 더 우세한지 그 경쟁관계를 파악하여 플럭의 크기의 증감을 예측할 수 있게 농도(?)와 난류소산매개변수(?)를 이용하여 $c/G^{0.5}$로 매개화하였다. 실험 결과, 순방향 흐름을 제외하고 스토크스파 흐름 조건을 이용하여 진행된 모의에서는 플럭의 크기와 농도가 반비례하는 현상을 관찰할 수 없었으며 $c/G^{0.5}$ 의 변화 역시 흐름의 속도와 농도가 더 큰 지점에서 큰 값을 가지는 일반적인 결과를 나타내었다. 그러나 같은 조건에서 순방향흐름을 추가하여 모의한 결과에서는 플럭의 크기와 농도가 반비례하는 현상을 나타냈다. 연직 방향 $c/G^{0.5}$의 변화를 나타낸 그래프에서 응집과 파괴의 우세에 따라 $c/G^{0.5}$ 가 역전되는 현상을 확인하였다. 즉, 플럭의 크기는 난류의 구조와 그 영향에 의해 농도와 비례관계를 갖지 않을 수도 있다고 판단된다. 또한 본 연구에서 정상류 흐름 조건의 유무에 따라 플럭의 크기와 농도가 비례하거나 반비례하는 상반된 결과를 보였다. 정상류 흐름 조건이 난류의 강도에 큰 역할을 하며 이에 따라 비선형 관계에 영향을 끼친다는 것을 발견하였다. 그러나 흐름의 영향에 대한 더 자세한 분석은 본 연구에서 진행되지 않았으며 향후 연구 시에 분명히 고려되어야 할 사항이다.

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Predicting Successful Conservative Surgery after Neoadjuvant Chemotherapy in Hormone Receptor-Positive, HER2-Negative Breast Cancer

  • Ko, Chang Seok;Kim, Kyu Min;Lee, Jong Won;Lee, Han Shin;Lee, Sae Byul;Sohn, Guiyun;Kim, Jisun;Kim, Hee Jeong;Chung, Il Yong;Ko, Beom Seok;Son, Byung Ho;Ahn, Seung Do;Kim, Sung-Bae;Kim, Hak Hee;Ahn, Sei Hyun
    • Journal of Breast Disease
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    • v.6 no.2
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    • pp.52-59
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    • 2018
  • Purpose: This study aimed to determine whether clinicopathological factors are potentially associated with successful breast-conserving surgery (BCS) after neoadjuvant chemotherapy (NAC) and develop a nomogram for predicting successful BCS candidates, focusing on those who are diagnosed with hormone receptor (HR)-positive, human epidermal growth factor receptor 2 (HER2)-negative tumors during the pre-NAC period. Methods: The training cohort included 239 patients with an HR-positive, HER2-negative tumor (${\geq}3cm$), and all of these patients had received NAC. Patients were excluded if they met any of the following criteria: diffuse, suspicious, malignant microcalcification (extent >4 cm); multicentric or multifocal breast cancer; inflammatory breast cancer; distant metastases at the time of diagnosis; excisional biopsy prior to NAC; and bilateral breast cancer. Multivariate logistic regression analysis was conducted to evaluate the possible predictors of BCS eligibility after NAC, and the regression model was used to develop the predicting nomogram. This nomogram was built using the training cohort (n=239) and was later validated with an independent validation cohort (n=123). Results: Small tumor size (p<0.001) at initial diagnosis, long distance from the nipple (p=0.002), high body mass index (p=0.001), and weak positivity for progesterone receptor (p=0.037) were found to be four independent predictors of an increased probability of BCS after NAC; further, these variables were used as covariates in developing the nomogram. For the training and validation cohorts, the areas under the receiver operating characteristic curve were 0.833 and 0.786, respectively; these values demonstrate the potential predictive power of this nomogram. Conclusion: This study established a new nomogram to predict successful BCS in patients with HR-positive, HER2-negative breast cancer. Given that chemotherapy is an option with unreliable outcomes for this subtype, this nomogram may be used to select patients for NAC followed by successful BCS.

Characterization of Human Dental Pulp Cells from Supernumerary Teeth by Using Flow Cytometry Analysis (유세포 분석을 통한 과잉치 치수 유래 세포의 줄기세포 특성 연구)

  • You, Yonsook;Kim, Jongbin;Shin, Jisun;Lee, June-Haeng;Kim, Jongsoo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.46 no.3
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    • pp.337-342
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    • 2019
  • The aim of this study was to analyze cells from human dental pulp tissue of impacted supernumerary teeth as stem cells with flow cytometry. Human dental pulp cells from 15 supernumerary teeth were identified their characteristics as stem cells by expression of mesenchymal stem cell markers through flow cytometry analysis at passage 3 and passage 10. Cluster of differentiation (CD) 73, CD 90, CD 34, CD 45 and STRO-1 cell surface markers were used to figure out characteristics of dental pulp stem cells from supernumerary teeth. At passage 3, the cell population showed positive expression of CD 73, CD90 and STRO-1, lacked expression of CD 34 and CD 45. At passage 10, CD 73, CD 90 and STRO-1 showed positive expression while CD 34 and CD 45 showed negative expression. This study indicated that dental pulp stem cells of supernumerary teeth had the properties of mesenchymal stem cells at both early and late passage. Impacted supernumerary teeth could be considered as a noble source of stem cells because of rapid growth and maintaining characteristics of stem cells until late passage.

5 Year Cumulative Survival Rate of Composite Resin Restorations in Permanent First Molars (제1대구치 복합레진 수복의 5년 누적 생존율)

  • Jung, Yoonsun;Shin, Jisun
    • Journal of the korean academy of Pediatric Dentistry
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    • v.46 no.3
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    • pp.310-317
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    • 2019
  • The purpose of this retrospective study was to evaluate the survival rate of composite resin restorations in permanent first molars in pediatric patients focusing on the influence of risk factors related to patients and teeth. 172 patients (6 - 12 years old) who had their permanent first molars restored with composite resin from July 2010 to July 2012 were investigated. From the dental records, the influence of the risk factors on the survival of restorations was assessed. Location of teeth, classification of cavities, patients' age and caries risk were included as risk factors in this study. The caries risks of patients were evaluated by the value of the decayed-missing-filled teeth index with the records of patients taken at 5 years old. Among 354 restorations, 272 restorations retained and 82 restorations were replaced. The overall cumulative survival rate at 5 years was 73.9%. The main reason for replacement of restorations was secondary caries (81.7%). Patients with older age group and with lower caries risk group showed higher survival rate of restorations. No statistically significant influence was detected between the survival rates and the possible risk factors : location of teeth, patients' age and caries risk. The survival rate of restorations was significantly affected by the classification of the cavities (p = 0.002).

Characteristics of Images in Image-based SNS and User Satisfaction - Focusing on Instagram and Pinterest - (이미지 기반 SNS에 나타난 이미지의 속성과 사용자 만족 인스타그램과 핀터레스트를 중심으로)

  • Yoon, Jisun;Ryoo, Han Young
    • Journal of the HCI Society of Korea
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    • v.14 no.1
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    • pp.5-13
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    • 2019
  • SNS has been advanced from first to third generation by changing its service format in various ways. Nowadays, image-based SNS such as instagram and pinterest where users communicate via images has become popular as third generation service. Due to the fact that users communicate especially through images, image-based SNS utilizes images in different ways compared to other SNS. This study derived various characteristics of images in image-based SNS, and observed how users perceive each of them differently. Also, relationship between the characteristics and user satisfaction on image-based SNS is analyzed. The characteristics include 6 items; 'implicity', 'recordability', 'expressing identity', 'indirect experience', 'temporary amusement', and 'stimulating desire.' As a result of comparing user perception regarding those 6 characteristics, recordability and indirect experience were highly recognized than other characteristics. Also, according to users' age, motivation of using image-based SNS, and number of followers they have, users perceived each characteristic in different level. Finally, relationship between the characteristics and user satisfaction was analyzed, and the result showed that indirect experience had positive influence to user satisfaction. Regarding indirect experience, it was highly perceived by users and also had positive influence to their satisfaction, which means it is the most typical characteristic of image-based SNS.

Risk of Smoke Occurring in the Combustion of Plastics (플라스틱의 연소 시 발생하는 연기 위험성에 관한 연구)

  • You, Jisun;Chung, Yeong-jin
    • Fire Science and Engineering
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    • v.33 no.1
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    • pp.69-75
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    • 2019
  • In this study, the combustibility of five types of plastic plates, fiber reinforced plastic (FRP), polystyrene (PS), polycarbonate (PC), polypropylene (PP), and polyvinyl chloride (PVC), were tested using a cone calorimeter (ISO 5660). The PVC plate showed a $44.65kW/m^2$ lower peak heat release rate (HRR) and a $30.97kW/m^2$ lower maximum average rate of heat emission than the other four types of plastics, whereas the PS plate showed a $773.44kW/m^2$ higher peak HRR and $399.14kW/m^2$ higher maximum average rate of heat emission. The PC plate and PS plate showed the highest HRR by a maximum of 3.88 times in $CO_{mean}$ yields, while the PS pate and PP plate showed the highest HRR by a maximum 4.88 times in $CO_{2mean}$ yields. In addition, the smoke performance index (SPI) of the PS plate decreased by 74.81%~95.99%; the smoke growth index (SGI) increased to 76%~300%; the smoke intensity (SI) also increased to 917.73% ~ 9607.57%, and the danger of smoke increased. The PS plate was found to have the highest risk of life damage due to smoke on the thermal and smoke sides.

Gene Expression of Supernumerary Dental Pulp Related to the Subculture Speed: A Pilot Study (계대 배양 속도가 다른 과잉치 치수유래 줄기세포 간 유전자 발현 특성)

  • Lee, Yookyung;Kim, Jongsoo;Shin, Jisun;Kim, Jongbin
    • Journal of the korean academy of Pediatric Dentistry
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    • v.46 no.2
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    • pp.219-225
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    • 2019
  • The purpose of this study was to investigate the odontoblast gene expression related to the subculture speed of supernumerary dental pulp stem cells (sDPSCs). The stem cell is undifferentiated cells which has the ability to differentiate into various cells. Specific stimulation or environment induces cell differentiation, and these differentiation leads to bone or muscle formation. 20 sDPSCs were obtained from 20 children under aseptic condition. During the culture through the 10th passage, the third passage cells which showed short subculture period and 10th passage cells which showed long subculture period were earned. Each cell was divided into differentiated group and non-differentiated group. Quantitative real-time polychain reaction (q-RT-PCR) was performed for each group. The genes related to odontoblast differentiation, Alkaline Phosphatase (ALP), Osteocalcin (OCN), Osteonectin (ONT), Dentin sialophosphoprotein (DSPP) and Dentin matrix acidic phosphoprotein 1 (DMP-1), were measured. Differentiated cells showed more gene expression levels. Undifferentiated cells showed higher gene expression level in 10th passages but differentiated cells showed higher gene expression level in 3rd passages. Cells that showed faster subculture period showed relatively lower gene expression level except for OCN and DSPP.

Korean Elementary Students' Understanding about Scientific Inquiry using VASI-E Questionnaire (초등학생의 과학 탐구의 특징에 대한 이해 -VASI-E를 바탕으로-)

  • Yoo, Hye-jin;Park, Jisun;Lederman, Judith S.;Lederman, Norman G.;Bartels, Selina;Jimenez, Juan
    • Journal of The Korean Association For Science Education
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    • v.41 no.2
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    • pp.83-92
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    • 2021
  • The purpose of this study is to investigate elementary school students' understandings about scientific inquiry. Data were collected from 119 elementary students who are in the 4th grade using the Views About Scientific Inquiry questionnaire for elementary students (VASI-E). We also conducted semi-structured interviews of 21 students from 119 students who responded to VASI-E. Students' responses were analyzed as naive, mixed, or informed views on each aspect of scientific inquiry that VASI-E includes. We found that, first, 53.8% of students have mixed views, and 30.3% of students have informed views, and 16% of students have naive views on the knowledge 'investigation begin with a question'. Second, 54.6% of students have naive views, 37.8% of students have mixed views, and 7.6% of students have informed views on the knowledge 'scientists use many methods to answer their questions.' Third, 47.9% of students have informed views, 34.5% of students have naive views, and 17.6% of students have mixed views on 'procedures guided by question asked.' Fourth, 55.5% of students have mixed views, 42% of students have informed views, and only 2.5% of students have naive views on 'conclusions must be consistent with data and explanations come from data and prior knowledge.' Based on the results, implications for teaching and learning scientific inquiry at elementary level in Korea were discussed.

A Case Study of Group Music Psychotherapy for Improving Adolescents' Awareness of the Motivation Behind Their Excessive Online Gaming (게임 과몰입 청소년의 게임 이용동기 인식을 위한 그룹 음악심리치료 사례)

  • Song, Jisun
    • Journal of Music and Human Behavior
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    • v.17 no.2
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    • pp.1-28
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    • 2020
  • This case study aimed to investigate changes in adolescents' awareness of the motivation behind their excessive internet gaming after group music psychotherapy. Five middle school students participated in six 60-minute group sessions over 4 weeks. The group music psychotherapy program was developed to help participants understand their implicit reasons for excessive internet gaming. Verbal responses were obtained from pre-program and post-program interviews and original lyrics created by participants during program were collected for analysis. Obtained data were analyzed in terms of emotional and cognitive aspects in relation to the participants' awareness of the motivation behind their excessive gaming. The results showed that song writing as creative musical process allowed participants to be aware of positive and negative influence of gaming on themselves and express their motivation to change their perception on gaming behavior. Also, the participants reported that the use of musical product for their daily lives could be an effective coping strategy to manage their gaming behaviors and an alternative for gaming. The findings from this study support that group music psychotherapy can be an effective approach to promote awareness of adolescents' motives for excessive internet gaming and to help adolescents better manage their gaming behaviors.

Effect of Aluminum Chloride Hemostatic Agent on Bonding Strength of RMGIC in Primary Tooth (염화알루미늄 지혈제가 유치와 레진강화형 글라스아이오노머 시멘트의 결합강도에 미치는 영향)

  • Woo, Seung-Hee;Shin, Jisun;Lee, Joonhaeng;Han, Miran;Kim, Jong Soo
    • Journal of the korean academy of Pediatric Dentistry
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    • v.48 no.4
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    • pp.397-404
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    • 2021
  • The purpose of this study was to evaluate the effect of a hemostatic agent containing aluminum chloride on the shear bond strength of resin-modified glass ionomer cement (RMGIC) to the dentin of primary teeth. Thirty-six extracted non-carious human primary teeth were collected in this study. Dentin surfaces were cut and polished. The specimens were randomly divided into 4 groups; group I: RMGIC without conditioning; group II: polyacrylic acid (PAA), RMGIC; group III: aluminum chloride, RMGIC; group IV: aluminum chloride, PAA, RMGIC. All teeth were thermocycled between 5.0℃ and 55.0℃ for 5000 cycles. Fifteen specimens from each group were subjected to shear bond strength test and 3 specimens from each group were inspected using scanning electron microscopy (SEM) and energy dispersive X-ray spectroscopy. The mean shear bond strength of each group was as follows: 4.04 ± 0.88 MPa in group I, 8.29 ± 1.40 MPa in group II, 1.39 ± 0.47 MPa in group III, 6.24 ± 2.76 MPa in group IV. There were significant differences among all groups (p < 0.001). SEM image of the dentinal tubules were partially exposed in group III and group IV. Fully exposed dentinal tubules were found in group II. In conclusion, aluminum chloride decreased the shear bond strength of RMGIC to dentin, regardless of PAA conditioning.