• 벤처창업연구
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• 제15권4호
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• pp.17-25
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• 2020

벤처부채는 벤처의 스케일업 촉진을 위한 대표적인 자금공급 수단이다. 성장 단계에서 대규모 자금 공급이 필요한 벤처기업은 지분 희석 없이 벤처부채를 지렛대로 성장을 가속화할 수 있고, 벤처캐피탈은 투자 기업의 성장이 가속화됨으로써 신속히 투자자금을 회수할 수 있다. 은행은 벤처부채의 공급을 통해 대출에 편중된 자산운용을 다양화할 수 있고 자산수익률도 제고할 수 있다. 해외 실리콘밸리은행의 사례와 같이 벤처부채 공급을 위해서는 부채자본 공급자인 은행과 지분자본을 공급하는 벤처캐피탈의 긴밀한 협력이 전제되어야 한다. 이를 위한 시장 조성 방안으로 "신용위험 분담형 벤처대출"과 "벤처대출 풀링"을 제안한다. 전자는 모태펀드와 정책보증과 같은 정책금융기관이 벤처대출에 내재한 위험을 선별하거나 우선 인수함으로써 은행의 벤처투자 시장 참여를 촉진하며, 후자는 은행과 창업벤처전문 사모펀드가 공동으로 벤처대출을 증권화함으로써 은행의 개별적인 벤처대출 실행에 따른 부담을 감소시킨다.

• Journal of Plant Biotechnology
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• 제47권2호
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• pp.172-178
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• 2020

Fruit-specific promoters play an important role in the improvement of traits, such as fruit quality through genetic engineering. In tomato, the development of fruit-specific promoters was previously reported, but less attention has been paid to the promoters involved in the fruit development stage. In this study, we characterized the gene expression patterns of tomato alcohol dehydrogenase 2 (SlAdh2) in various tissues of wild-type tomato (cv. Ailsa Craig). Our findings revealed that SlAdh2 expression levels were higher in the developing fruit than in the leaves, stems, and flowers. The ProSlAdh2 region, which is expressed at different stages of fruit development, was isolated from tomato genomic DNA. Following this, it was fused with a β-glucuronidase reporter gene (GUS) and introduced into wild-type tomato using Agrobacterium-mediated transformation to evaluate promoter activity in the various tissues of transgenic tomato. The ProSlAdh2:GUS promoter exhibited strong activity in the fruit and weak activity in the stems, but displayed undetectable activity in the leaves and flowers. Interestingly, the promoter was active from the appearance of the green fruit (1 cm in size) to the well-ripened stage in transgenic tomatoes, indicating its suitability for transgene expression during fruit development and ripening. Thus, our findings suggest that ProSlAdh2 may serve as a potential fruit-specific promoter for genetic-based improvement of tomato fruit quality.

• Journal of Preventive Medicine and Public Health
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• 제50권5호
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• pp.311-319
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• 2017

Objectives: This article aimed to compare alcohol consumption between the populations of Queensland in Australia and Alberta in Canada. Furthermore, the associations between greater alcohol consumption and socio-demographic characteristics were explored in each population. Methods: Data from 2500 participants of the 2013 Alberta Survey and the 2013 Queensland Social Survey were analyzed. Regression analyses were used to explore the associations between alcohol risk and socio-demographic characteristics. Results: A higher rate of hazardous alcohol use was found in Queenslanders than in Albertans. In both Albertans and Queenslanders, hazardous alcohol use was associated with being between 18 and 24 years of age. Higher income, having no religion, living alone, and being born in Canada were also associated with alcohol risk in Albertans; while in Queenslanders, hazardous alcohol use was also associated with common-law marital status. In addition, hazardous alcohol use was lower among respondents with a non-Catholic or Protestant religious affiliation. Conclusions: Younger age was associated with greater hazardous alcohol use in both populations. In addition, different socio-demographic factors were associated with hazardous alcohol use in each of the populations studied. Our results allowed us to identify the socio-demographic profiles associated with hazardous alcohol use in Alberta and Queensland. These profiles constitute valuable sources of information for local health authorities and policymakers when designing suitable preventive strategies targeting hazardous alcohol use. Overall, the present study highlights the importance of analyzing the socio-demographic factors associated with alcohol consumption in population-specific contexts.

• 한국소음진동공학회:학술대회논문집
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• 한국소음진동공학회 1994년도 추계학술대회논문집; 한국종합전시장, 18 Nov. 1994
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• pp.116-120
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• 1994

최근 항공우주 및 생산자동화 분야의 급격한 발달에 따라 정밀도와 효율성을 향상시키기 위해 저중량, 고강도 구조물이 요구된다. 그러나 경량화 추세로 인해 수반되는 구조물의 유연성 증가로 외력에 대한 구조응답의 진폭이 커지고 구조물의 피로 수명이 단축되어 매우 위험한 상황에 이를 수 있다. 이런 바람직하지 않은 진동현상을 제어하기 위해 여러 제어이론을 응용한 진동억제시스템의 연구가 활발하며, 신소재인 압전재료의 개발로 새로운 방향이 제시되고 있다. 압전재료는 유연한 구조물에 부착되어 압전재료의 수축, 팽창 운동에 의해 발생된 에너지를 부착된 구조물에서의 제어력으로 사용되어, 진동 혹은 자세 및 형상 제어에 활용되고 있다. 압전재료에 대한 연구로는 Crawley, de Luis3가 보의 표면 혹은 내부에 압전세라믹을 부착하여 액튜에이터로 사용하는 경우 집중모멘트를 가하는 역할을 함을 밝혔고, Hanagud, obal은 압전재료를 센서와 액튜에이터로 사용해 복합재료 보에 대한 최적 진동제어 알고리즘을 개발, 그 성능에 대한 효과를 조사하였고 임의의 위치에 부착된 센서 및 액튜에이터를 고려한 복합재료 보의 운동방정식을 유한요소법을 이용 유도하였으며 변위율 피드백(rate feedback)과 모달피드백(modal feedback) 제어기를 적용하여 진동제어 효과를 고찰하였다. 그리고 Tomas, James, Hubbard는 압전필름을 액튜에이터로 사용해 복합재료 보에 Liapunov 제어기와 변위율 피드백 제어기를 사용하여 능동감쇠기를 설계하였고, Lee, Chaing, Sullivan은 압전필름을 센서와 액튜에이터로 사용해 평판에 변위율 피드백 제어기를 적용한 능동감쇠기를 설계하고 실험적으로 수행하였다. Base가 백색잡음가진을 지속적으로 받을 때 보끝의 움직임이 최소가 되도록 제어하고자 연구를 수행 중인 바 그 결과로소 본 논문에서는 적용시켰고 F-P-K 방정식을 이용해 확률영역으로 변환하여 LQR 제어기와 pole allocation 제어기를 시스템에 적용시켜 우수한 특성을 갖음을 제어 시뮬레이션의 결과를 통해 입증하였다.

• 한국환경농학회지
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• 제25권4호
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• pp.289-296
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• 2006

Various drying conditions, temperatures (40 to $80^{\circ}C$) and durations (overnight to 72 hrs), for the particulate organic matter (POM) fraction after wet-sieving size fractionation have been applied for determination of POM contents in the weight loss-on-ignition method. In this study, we investigated the optimum drying condition for POM fraction in quantification of POM and/or mineral-associated organic matter (MOM; usually indirectly estimated). The influence of the drying conditions on quantifying POM was dependent upon soil properties, especially the amount of soil organic components. In relatively high organic soils (total carbon > 40 g/kg in this study), the POM values were significantly higher (overestimated) with drying at $55^{\circ}C$ than those values at $105^{\circ}C$, which were, for example, 173.2 and 137.3 mg/kg, respectively, in a soil studied. However, drying at $55^{\circ}C$ for longer than 48 hrs of periods produced consistent POM values even though the values were much higher than those at $105^{\circ}C$. Thus, indirect estimates of MOM (MOM = SOM-POM) also tended to be significantly impacted by the dry conditions. Therefore, we suggest POM fractions should be dried at $105^{\circ}C$ for 24 hrs as determining POM and MOM contents. If the POM traction is needed to be dried at a lower temperature (e.g. $55^{\circ}C$) with a specific reason, at least 48 hrs of drying period is necessary to obtain consistent POM values, and a moisture correction factor should be determined to adjust the values back to a $105^{\circ}C$ weight basis.

• 한국가구학회지
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• 제19권6호
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• pp.411-419
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• 2008

Xylia xylocarpa is fast-growing trees that are currently planted on trial basis in Sabah, Malaysia. The wood quality of trees grown in Sabah may differ from those grown in other places due to the environmental factors. Five 9-year-old trees of each species were extracted from their respective plots at Luasong, Tawau. Wood specimens were prepared from three height levels; bottom, middle and top, at the inner and outer radial positions. The within-tree and between-tree variations of physical properties of these species were analyzed. The basic density, oven-dry density and green moisture content(MC) are 0.72g/$cm^3$, 0.78g/$cm^3$ and 49.8% respectively. The shrinkage from green to oven-dry conditions for the radial and tangential directions were 3.35% and 5.76%, respectively. The trends of within-tree variations for most properties were more consistent in radial rather than vertical direction. This suggests diameter growth to be a more important factor contributing to the variations compared to height. Samples from the outer part of the stem were found to have higher density, shrinkage and mechanical strengths. The between-trees variations of some wood properties were found to be significantly different, probably due to genetic and micro-environmental factors. Significant correlation was recorded among the physical properties of the species. The true potential of X. xylocarpa for end-uses would be enhanced by further research such as the study on properties of wood from different sites and other properties like durability, seasoning, processing and machining characteristics. The characteristics of X. xylocarpa are comparable to a number of local popular hardwood species, indicating its suitability for heavy construction uses.

• The Korean Journal of Physiology and Pharmacology
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• 제3권6호
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• pp.571-578
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• 1999

This study evaluated the effects of PKC activation using phorbol 12-myristate 13-acetate (PMA) and PKC inhibition using the isoquinoline sulfomide derivative H-7 on hemodynamics and glucoregulation in the isolated perfused rat liver. Livers were isolated from fed male Holtzman rats and perfused with Krebs Ringer bicarbonate solution under a constant flow of 50 ml/min at $35^{\circ}C.$ Portal vein pressure, glucose and lactate concentrations in the medium and oxygen consumption rates were continuously monitored by a Grass polygraph, YSI glucose and lactate monitors, and a YSI oxygen monitor, respectively. PMA at concentration of 2 to 200 nM increased the portal vein pressure, glucose and lactate production, but decreased oxygen consumption rate in a dose-dependent fashion. H-7 $(200\;{\mu}M)$ attenuated PMA (50 nM)-induced vasoconstriction $(15.1{\pm}1.36\;vs\;10.56{\pm}1.17\;mmHg),$ glucose production rate $(91.3{\pm}6.15\;vs\;71.8{\pm}2.50\;{\mu}moles/g/hr),$ lactate production rate $(72.4{\pm}6.82\;vs\;53.6{\pm}4.82\;{\mu}moles/g/hr)$ and oxygen consumption rate $(33.7{\pm}1.41\;vs\;27.9{\pm}1.75\;{\mu}l/g/min).$ The effects of PMA were blocked either by addition of verapamil $(9\;{\mu}M)$ or perfusion with $Ca^{2+}-free$ KRB. These results suggest that the hemodynamic and glucoregulatory changes in the perfused rat liver are mediated by protein kinase C activation and require $Ca^{2+}$ influx from the extracellular fluid.

• 패션비즈니스
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• 제22권4호
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• pp.76-92
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• 2018

The purpose of this study is to find the meaning of women's fashion in the city culture of Paris in the nineteenth century by examining paintings by the Impressionists. The research method was based on literature survey and visual examination paintings, 224 paintings(by ${\acute{E}}douard$ Manet, James Tissot, Edgar DeGas, Gustave Cailleboat, Jean $B{\acute{e}}raud$, Pierre-Auguste Renoir) were analyzed in this study. The results are as follows: In the nineteenth century, Paris was a new city with new department stores. Department stores were centers of consumer culture, where the power of capital appeared rather than class. The spatial backgrounds of Impressionist paintings were places where they could see the consumption and leisure culture of urban people, such as outdoor parks, cafes, theaters, ballrooms, bars, streets, and the boats. As for the characteristics of women's fashion in paintings, it was found that various changes of artificial silhouettes were developed. Various frills, ruffles, gatherings, and pleats were thought to have been made by machines. In the urban space, many of the women's costumes stood out because of the black color. Not only the black color came to represent widows and mourning but the black outfits worn by women enhanced their sensual appearances. Women's fashion expressed in Impressionist paintings eventually contained a modern meaning that changed from 'class symbol' to 'expression of taste'. And the symbol of consumer and leisure culture showed, and a Demimonde's fashion became a trendsetter, and painters were used as an important element expressing modernity.

• Wind and Structures
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• 제19권3호
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• pp.339-352
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• 2014

This paper discusses the appropriate duration for basic gust wind speeds in wind loading codes and standards, and in wind engineering generally. Although various proposed definitions are discussed, the 'moving average' gust duration has been widely accepted internationally. The commonly-specified gust duration of 3-seconds, however, is shown to have a significant effect on the high-frequency end of the spectrum of turbulence, and may not be ideally suited for wind engineering purposes. The effective gust durations measured by commonly-used anemometer types are discussed; these are typically considerably shorter than the 'standard' duration of 3 seconds. Using stationary random process theory, the paper gives expected peak factors, $g_u$, as a function of the non-dimensional parameter ($T/{\tau}$), where T is the sample, or reference, time, and ${\tau}$ is the gust duration, and a non-dimensional mean wind speed, $\bar{U}.T/L_u$, where $\bar{U}$ is a mean wind speed, and $L_u$ is the integral length scale of turbulence. The commonly-used Durst relationship, relating gusts of various durations, is shown to correspond to a particular value of turbulence intensity $I_u$, of 16.5%, and is therefore applicable to particular terrain and height situations, and hence should not be applied universally. The effective frontal areas associated with peak gusts of various durations are discussed; this indicates that a gust of 3 seconds has an equivalent frontal area equal to that of a tall building. Finally a generalized gust response factor format, accounting for fluctuating and resonant along-wind loading of structures, applicable to any code is presented.

• Journal of Microbiology and Biotechnology
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• 제23권8호
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• pp.1060-1069
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• 2013

Genome organization near cyclomaltodextrinases (CDases) was analyzed and compared for four different hyperthermophilic archaea: Thermococcus, Pyrococcus, Staphylothermus, and Thermofilum. A gene (CL1_0884) encoding a putative CDase from Thermococcus sp. CL1 (tccd) was cloned and expressed in Escherichia coli. TcCD was confirmed to be highly thermostable, with optimal activity at $85^{\circ}C$. The melting temperature of TcCD was determined to be $93^{\circ}C$ by both differential scanning calorimetry and differential scanning fluorimetry. A size-exclusion chromatography experiment showed that TcCD exists as a monomer. TcCD preferentially hydrolyzed ${\alpha}$-cyclodextrin (${\alpha}$-CD), and at the initial stage catalyzed a ring-opening reaction by cleaving one ${\alpha}$-1,4-glycosidic linkage of the CD ring to produce the corresponding single maltooligosaccharide. Furthermore, TcCD could hydrolyze branched CDs (G1-${\alpha}$-CD, G1-${\beta}$-CD, and G2-${\beta}$-CD) to yield significant amounts (45%, 40%, and 46%) of isomaltooligosaccharides (panose and $6^2$-${\alpha}$-maltosylmaltose) in addition to glucose and maltose. This enzyme is one of the most thermostable maltogenic amylases reported, and might be of potential value in the production of isomaltooligosaccharides in the food industry.