• 미생물학회지
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• 제23권1호
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• pp.1-8
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• 1985

일산화 탄소를 이용한 enrichment 배양 방법을 통하여 흙으로부터 일산화탄소를 이용하여 성장 할 수 있는 세가지 종류 (JC1, JC2, HY1)의 호기성 Acinetobacter 들을 분리했다. 이세균들은 모두Gramdma성 세균들로 운동성이 없었으며, 지수성장기에는 간균의 형태를 나타내었으나 성장이 정지되었을 때에는 구균으로 변하였다. 이들은 페니실린에 대해 내성이 있었고 $42^{\circ}C$에서도 성장을 할 수 있었다. DNA의 G+C함량은 43%-44.5%이였고 모든 세균에서 oxidase의 활성이 나타나지 않았다. 이 세균들의 coloy들은 모두 둥글고 매끄러웠으며 연한 노란색을 띄었다. 이들은 또 여러가지 종류의 당이나 유기산, 아미노산. 알코올 등을 이용하여 생장할 수 있였다. JC1과 J JC2 벚 HY1이 30%의 일산화탄소를 이용하여 $30^{\circ}C$에서 성장할 때의 doubling time은 각각 19시간. 25시간, 그리 고 35시간 이었다. JC1의 자가영양적 성장을 위한 최적조건은 pH가 6.8이였L 온도는 $42^{\circ}C$ 그리고 일산화탄소의 농도는 30%이였다. JC1 의 자가영양적 성장에는 몰리브데늄이 필요치 않았고, 또 이 세균은 100ppm의 CO만으로도 성장할 수 있는 것으로 밝혀졌다.

• 한국초전도ㆍ저온공학회논문지
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• 제4권1호
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• pp.1-3
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• 2002

Single Josephson junctions, which are of cross type, of $50 ${\mu}{\textrm}{m}$ {\times} 50 ${\mu}{\textrm}{m}$$ were fabricated under several oxidation conditions to Investigate controllabilities of critical current density (Jc) with the standard KRISS processes. Considering that the self-field effect suppresses the observed critical current (Ice) at high Jc region, we could reasonably estimate Jc values from I-V observations. The dependence of the obtained Jc as a function of exposure, which is equal to pressure (P) times time (t), was well fitted to a curve of Jc ~ (Pt)-0.34. The maximum Jc value at the controllability margin was found to be 3 kA/cm$^2$with the current equipment set up.

• Korean Journal of Mathematics
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• 제22권1호
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• pp.91-121
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• 2014

Let X and Y be vector spaces. It is shown that a mapping $f:X{\rightarrow}Y$ satisfies the functional equation ${\ddag}$ $$2df(\frac{x_1+{\sum}_{j=2}^{2d}(-1)^jx_j}{2d})-2df(\frac{x_1+{\sum}_{j=2}^{2d}(-1)^{j+1}x_j}{2d})=2\sum_{j=2}^{2d}(-1)^jf(x_j)$$ if and only if the mapping $f:X{\rightarrow}Y$ is additive, and prove the Cauchy-Rassias stability of the functional equation (${\ddag}$) in Banach modules over a unital $C^*$-algebra, and in Poisson Banach modules over a unital Poisson $C^*$-algebra. Let $\mathcal{A}$ and $\mathcal{B}$ be unital $C^*$-algebras, Poisson $C^*$-algebras, Poisson $JC^*$-algebras or Lie $JC^*$-algebras. As an application, we show that every almost homomorphism $h:\mathcal{A}{\rightarrow}\mathcal{B}$ of $\mathcal{A}$ into $\mathcal{B}$ is a homomorphism when $h(d^nuy)=h(d^nu)h(y)$ or $h(d^nu{\circ}y)=h(d^nu){\circ}h(y)$ for all unitaries $u{\in}\mathcal{A}$, all $y{\in}\mathcal{A}$, and n = 0, 1, 2, ${\cdots}$. Moreover, we prove the Cauchy-Rassias stability of homomorphisms in $C^*$-algebras, Poisson $C^*$-algebras, Poisson $JC^*$-algebras or Lie $JC^*$-algebras, and of Lie $JC^*$-algebra derivations in Lie $JC^*$-algebras.

• Journal of Microbiology
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• 제40권3호
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• pp.237-240
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• 2002

A carboxydotrophic bacterium, isolated from a soil sample in Seoul, was classified initially as Acinetobacter sp. strain JC1 DSM 3803. Chemotaxanomic properties, analysis of the 16s rDNA sequence, fatty acid content, and molecular Phylogenetic analysis based on rpoB gene, however, suggested that this bacterium belongs to the genus, Mycobacterium. On the basis of this evidence, it is proposed that Acinetobacter sp. strain JC1 DSM 3803 be reclassified as Mycobacterium sp. strain JC1 DSM 3803.

• Biomolecules & Therapeutics
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• 제25권4호
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• pp.404-410
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• 2017

Benzylideneacetophenone derivative (1E)-1-(4-hydroxy-3-methoxyphenyl) hept-1-en-3-one (JC3) elicited cytotoxic effects on MDA-MB 231 human breast cancer cells-radiation resistant cells (MDA-MB 231-RR), in a dose-dependent manner, with an $IC_{50}$ value of $6{\mu}M$ JC3. JC3-mediated apoptosis was confirmed by increase in sub-G1 cell population. JC3 disrupted the mitochondrial membrane potential, and reduced expression of anti-apoptotic B cell lymphoma-2 protein, whereas it increased expression of pro-apoptotic Bcl-2-associated X protein, leading to the cleavage of caspase-9, caspase-3 and poly (ADP-ribose) polymerase. In addition, JC3 activated mitogen-activated protein kinases, and specific inhibitors of these kinases abrogated the JC3-induced increase in apoptotic bodies. JC3 increased the level of intracellular reactive oxygen species and enhanced oxidative macromolecular damage via lipid peroxidation, protein carbonylation, and DNA strand breakage. Considering these findings, JC3 is an effective therapy against radiation-resistant human breast cancer cells.

• 한국유기농업학회지
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• 제12권1호
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• pp.101-114
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• 2004

This study was carried out to clarify the effects of antagonistic microorganism, Bacillus sp. JC181 isolated from the greenhouse soil grown cucumber plants on the growth inhibition of plant pathogen, fusarium wilt (Fusarium oxysporum) occurred in cucumber plants in greenhouse. Antagonistic bacterial strains were isolated and were investigated into the antifungal activity of the antagonistic microorganism against fusarium wilt. Screened fourteen bacterial strains which strongly inhibited F. oxysporum were isolated from thc greenhouse soil grown cucumber plants, and the best antagonistic bacterial strain designated as JC181, was finally selected. Antagonistic bacterial strain JC181 was identified to be the genus Bacillus sp. based on the morphological and biochemical characterization. Bacillus sp. JC181 showed 58.2% of antifungal activity against the plant pathogen growth of F. oxysporum. By the bacterialization of culture broth and heated filtrates of culture broth, Bacterial strain, Bacillus sp. JC181. showed 91.2% and 260% of antifungal activity against F. oxysporum, respectivrly.

• Restorative Dentistry and Endodontics
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• 제20권2호
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• pp.839-842
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• 1995

In its study, We investigated the effects of Areca catechu L on the growth and acid production of Streptococcus mutans JC-2 in broth system and the activity of glucosyltransferase. The results were summarized as follow; 1. The growth of Streptococcus mutans JC-2 was suppressed by adding Areca catechu L in broth system. Especially, its inhibitory effect was significant at 2,000ppm of concentration. 2. Areca catechu L decreased the acid production of Streptococcus mutans JC-2. Decrease of pH according to acid production was less in presence of Areca catechu L than in absence. 3. Areca catechu L exerted the inhibitory effect against glucosyltransferase activity form Streptococcus mutans JC-2.

• Journal of Microbiology
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• 제44권2호
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• pp.243-247
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• 2006

Mycobacterium sp. strain JC1 was capable of growth on benzylamine as a sole source of carbon and energy. The primary deamination of benzylamine was mediated by an inducible amine oxidase, which can also oxidize tyramine, histamine, and dopamine. Inhibitor study identified this enzyme as a copper-containing amine oxidase sensitive to semicarbazide.

• 대한한의학방제학회지
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• 제32권1호
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• pp.39-49
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• 2024

Objectives : The purpose of this study was to investigate the molecular targets and pathways of anti-inflammatory effects of Jakyakgamchotang with corydalis tuber (JC) using network pharmacology. Methods : The compounds in constituent herbal medicines of JC were searched in TCM systems pharmacology (TCMSP). Target gene informations of the components were collected using chemical-target interactions database provided by Pubchem. Afterwards, network analysis between compounds and inflammation-related target genes was performed using cytoscape. Go enrichment analysis and Kyoto Encyclopedia of Genes and Genomes (KEGG) analysis were performed on inflammation-related targets using DAVID database. Results : 70 active compounds related to inflammation were identified, and 295 target genes related to the anti-inflammatory activity of the compound of JC were identified. In the Go biological process DB and KEGG pathway DB, "inflammatory response", "cellular response to lipopolysaccharide", "positive regulation of interleukin-6 production", and "positive regulation of protein kinase B. signaling", "positive regulation of ERK1 and ERK2 cascade", "positive regulation of I-kappaB kinase/NF-kappaB signaling", "negative regulation of apoptotic process", and "PI3K-Akt signaling pathway" were found to be mechanisms related to the anti-inflammatory effects related to the target genes of JC. The main compounds predicted to be involved in the anti-inflammatory effect of JC were quercetin, licochalcone B, (+)-catechin, kaempferol, and emodin. Conclusions : This study provides the molecular targets and potential pathways of JC on inflammation. It can be used as a basic data for using JC for various inflammatory disease in traditional korean medicine clinic.

• 대한수학회지
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• 제43권2호
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• pp.323-356
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• 2006

Let X and Y be vector spaces. It is shown that a mapping $f\;:\;X{\rightarrow}Y$ satisfies the functional equation $$mn_{mn-2}C_{k-2}f(\frac {x_1+...+x_{mn}} {mn})$$ $(\ddagger)\;+mn_{mn-2}C_{k-1}\;\sum\limits_{i=1}^n\;f(\frac {x_{mi-m+1}+...+x_{mi}} {m}) =k\;{\sum\limits_{1{\leq}i_1<... if and only if the mapping $f : X{\rightarrow}Y$ is additive, and we prove the Cauchy-Rassias stability of the functional equation $(\ddagger)$ in Banach modules over a unital $C^*-algebra$. Let A and B be unital $C^*-algebra$ or Lie $JC^*-algebra$. As an application, we show that every almost homomorphism h : $A{\rightarrow}B$ of A into B is a homomorphism when $h(2^d{\mu}y) = h(2^d{\mu})h(y)\;or\;h(2^d{\mu}\;o\;y)=h(2^d{\mu})\;o\;h(y)$ for all unitaries ${\mu}{\in}A,\;all\;y{\in}A$, and d = 0,1,2,..., and that every almost linear almost multiplicative mapping $h:\;A{\rightarrow}B$ is a homomorphism when h(2x)=2h(x) for all $x{\in}A$. Moreover, we prove the Cauchy-Rassias stability of homomorphisms in $C^*-algebras$ or in Lie $JC^*-algebras$, and of Lie $JC^*-algebra$ derivations in Lie $JC^*-algebras$.