• JSTS:Journal of Semiconductor Technology and Science
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• 제16권4호
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• pp.443-450
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• 2016

The linearization technique for low noise amplifier (LNA) has been implemented in standard $0.18-{\mu}m$ BiCMOS process. The MOS-BJT derivative superposition (MBDS) technique exploits a parallel LC tank in the emitter of bipolar transistor to reduce the second-order non-linear coefficient ($g_{m2}$) which limits the enhancement of linearity performance. Two feedback capacitances are used in parallel with the base-collector and gate-drain capacitances to adjust the phase of third-order non-linear coefficients of bipolar and MOS transistors to improve the linearity characteristics. The MBDS technique is also employed cascode configuration to further reduce the second-order nonlinear coefficient. The proposed LNA exhibits gain of 9.3 dB and noise figure (NF) of 2.3 dB at 2 GHz. The excellent IIP3 of 20 dBm and low-power power consumption of 5.14 mW at the power supply of 1 V are achieved. The input return loss ($S_{11}$) and output return loss ($S_{22}$) are kept below - 10 dB and -15 dB, respectively. The reverse isolation ($S_{12}$) is better than -50 dB.

• KIEAE Journal
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• 제3권3호
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• pp.27-34
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• 2003

As a result of supply-oriented housing policy of Korea since the 1960s, the number of apartment housing units has increased up to six million as of the end of 2001 that is 55% of total housing units. Although the needs of placid living environment increases according to the enhancement of residents' living standard, most of construction firms as apartment suppliers plan and design apartment buildings to maximize the profit and give rise the residents' petitions and troubles about floor impact noise. In consequence, the floor impact noise becomes one of principal problems of living environment, and the government placed the obligation of installing the noise isolation materials between upper and lower floors in 2001 and controlling the floor impact noise lower than 60dB from the middle of 2004. In other to provide the fundamental research data to enhance the reduction performance of floor impact sound, in this paper, the factors that influence on the floor impact noise are derived from the survey of many research papers and the performance of various materials used as noise reduction objects are compared and surveyed with the factors in the experiments in field and laboratory.

• Current Optics and Photonics
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• 제7권5호
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• pp.485-495
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• 2023

The pixel size in high-resolution complementary metal-oxide-semiconductor (CMOS) image sensors continues to shrink due to chip size limitations. However, the pixel pitch's miniaturization causes deterioration of optical performance. As one solution, a quad color filter (CF) array with pixel binning has been developed to enhance sensitivity. For high sensitivity, the microlens structure also needs to be optimized as the CF arrays change. In this paper, the covered microlens, which consist of four microlenses covered by one large microlens, are proposed for the quad CF array in the backside illumination pixel structure. To evaluate the optical performance, the suggested microlens structure was simulated from 0.5 ㎛ to 1.0 ㎛ pixels at the center and edge of the sensors. Moreover, all pixel structures were compared with and without in-pixel deep trench isolation (DTI), which works to distribute incident light uniformly into each photodiode. The suggested structure was evaluated with an optical simulation using the finite-difference time-domain method for numerical analysis of the optical characteristics. Compared to the conventional microlens, the suggested microlens show 29.1% and 33.9% maximum enhancement of sensitivity at the center and edge of the sensor, respectively. Therefore, the covered microlens demonstrated the highly sensitive image sensor with a quad CF array.

• 대한전자공학회논문지TC
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• 제47권10호
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• pp.80-85
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• 2010

본 논문에서는 LTE/DCS1800/USPCS1900 단말기용 MIMO 시스템 안테나를 제안하였다. 제안한 안테나는 IFA 형태를 기본으로 하여 광대역 특성을 얻기 위해 스태거 튜닝법을 사용 하였다. 또한 두 안테나 사이의 격리도를 개선하기 위해 두 안테나의 shorting point 사이에 suspended line을 연결하고, 연결된 suspended line에 커패시터와 인덕터를 추가하였다. 2.8cc($40{\times}10{\times}7mm$) 크기의 동일한 두 안테나를 $40{\times}60mm$ 크기의 시스템 그라운드 양 끝에 배치하였다. 제안된 안테나의 최적화 및 안테나 특성은 CST Microwave Studio을 이용하여 연구하였다. 시뮬레이션 결과 대역폭은 LTE 대역 class 13(746-787MHz), class 14(758-798MHz) 및 DCS1800/USPCS1900(1710-1990MHz)를 만족하였고 안테나 사이의 격리도는 각각 -12dB 및 -10dB이었다. 안테나 방사 효율은 LTE 대역에서 33%, DCS1800/USPCS1900 대역에서 45% 이었다.

• The Korean Journal of Physiology
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• 제30권2호
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• pp.197-208
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• 1996

Endosomes lower their internal pH by an ATP-driven proton pump, which is critical to dissociation of many receptor-ligand complexes, the first step in the intracellular sorting of internalized receptors and ligands. Endosomes are known to exhibit n great range of pH values that can vary between 5.0 and 7.0 within a single cell although the factors that regulate endosomal pH remain uncertain. To evaluate the morphological and topological differences of endosomes in the different stages, confocal microscopy was used. The early endosomes labeled with fluorescein isothiocyanate-dextran for 10 min at $37^{\circ}C$ were identifiable at the peripheral and tubule-vesicular endosome compartment. In contrast, the late endosomes formed by 10 min pulse and 20 min trace were located deeper in the cytoplasm and showed more vesicular features than early endosomes. For the purpose of determining whether ATP-dependent acidification was heterogeneous and whether the differences in acidification were attributed to differences in the activity of $Na^{+}-K^{+}$-ATPase and/or $Cl^{-}$ channel, endocytic compartments were fractionated into subpopulation using percoll gradient and measured ATP-dependent acidification. While all fractions exhibited ATP-dependent acidification activity, both the initial rate of acidification and extent of proton translocation were lower in early endosomes and gradually increased in late endosomes. Phosphorylation by PKA and ATP enhanced ATP-dependent acidification in both early and late endosomes, hut there was no difference in the degree of enhancement by phosphorylation between two subpopulations. When ATP-dependent acidification was determined in the presence or absence of vanadate ($Na_{3}VO_{4}$) or ouabain, only early endosomes exhibited the vanadate or ouabain dependent stimulation of acidification activity, suggesting the inhibition of $Na^{+}-K^{+}$-ATPase. Therefore, it seems probable that the inhibition of early endosome acidification by $Na^{+}-K^{+}$-ATPase observed in vitro at least in part plays a physiological role in controlling the acidification of early endosomes in vivo.

• 생약학회지
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• 제31권2호
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• pp.228-234
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• 2000

Effects of Houttuynia cordata on the level of lipid peroxide and the enzyme activities of the liver were investigated in bromobenzene-induced rats. Lipid peroxide content in liver was increased by bromobenzene. It was decreased when the methanol extract from the aerial parts of H. cordata was treated to the rat. The methanol extract reduced the activities of aminopyrine N-demethylase and aniline hydroxylase that increased by bromobenzene, however did not affect glutathione S-transferase activity. The methanol extract recovered the activity of epoxide hydrolase activity that decreased significantly by bromobenzene. We suggest that under our experimental conditions the extract might play an important play in the prevention of hepatotoxicity by reduction of aminopyrine N-demethylase and aniline hydroxylase activities as well as enhancement of epoxide hydrolase activity. Six phenolic compounds have been isolated from H. cordata and identified by means of spectral analysis as protocatechuic acid, quercetin, apigenin, afzelin, hyperoside and quercitrin.

• Structural Engineering and Mechanics
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• 제61권3호
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• pp.419-426
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• 2017

Recently, the transportation of dangerous explosive goods is increasing, which makes vehicle blasting accidents a potential threat for the safety of bridge structures. In addition, blasting accidents happen more easily when earthquake occurs. Excessive dynamic response of bridges under extreme loads may cause local member damage, serviceability issues, or even failure of the whole structure. In this paper, a new explosion-proof and aseismic system is proposed including cable support damping bearing and steel-fiber reinforced concrete based on the existing researches. Then, considering one 40m-span simply supported concrete T-bridge as the prototype, through scale model test and numerical simulation, the dynamic response of the bridge under three conditions including only earthquake, only blast load and the combination of the two extreme loads is obtained and the applicability of this explosion-proof and aseismic system is explored. Results of the study show that this explosion-proof and aseismic system has good adaptability to seism and blast load at different level. The reducing vibration isolation efficiency of cable support damping bearing is pretty high. Increasing cables does not affect the good shock-absorption performance of the original bearing. The new system is good at shock absorption and displacement limitation. It works well in reducing the vertical dynamic response of beam body, and could limit the relative displacement between main girder and capping beam in different orientation so as to solve the problem of beam falling. The study also shows that the enhancement of steel fibers in concrete could significantly improve the blast resistance of main beam. Results of this paper can be used in the process of antiknock design, and provide strong theoretical basis for comprehensive protection and support of girder bridges.

• Journal of Trauma and Injury
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• 제26권3호
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• pp.248-251
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• 2013

Introduction: A post-traumatic mesenteric arteriovenous fistula (AVF) is extremely rare. Case Report: A previously healthy 26-year-old male was injured with an abdominal stab wound. Computed tomography (CT) showed liver injury, pancreas injury and a retropancreatic hematoma. We performed the hemostasis of the bleeding due to the liver injury, a distal pancreatectomy with splenectomy and evacuation of the retropancreatic hematoma. On the 5th postoperative day, an abdominal bruit and thrill was detected. CT and angiography showed an AVF between the superior mesenteric artery (SMA) and the inferior mesenteric vein with early enhancement of the portal vein (PV). The point of the AVF was about 4 cm from the SMA's orifice. After an emergent laparotomy and inframesocolic approach, the isolation of the SMA was performed by dissection and ligation of adjacent mesenteric tissues which was about 6 cm length from the nearby SMA orifice, preserving the major side branches of the SMA, because the exact point of the AVF could not be identified despite the shunt flow in the PV being audible during an intraoperative hand-held Doppler-shift measurement. After that, the shunt flow could not be detected by using an intraoperative hand-held Doppler-shift measuring device. CT two and a half months later showed no AVF. There were no major complications during a 19-month follow-up period. Conclusion: Early management of a post-traumatic mesenteric AVF is essential to avoid complications such as hemorrhage, congestive heart failure and portal hypertension.

• 한국전자파학회논문지
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• 제26권4호
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• pp.349-356
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• 2015

본 논문은 LTE Band 5(824~894 MHz)에서 모노폴 타입과 슬롯 타입을 적용하여 저상관도를 갖는 MIMO(Multiple-Input Multiple-Output) 안테나 설계를 제안한다. 두 안테나 사이의 상관도 성능을 향상시키기 위하여 설치되는 그라운드의 특성 모드 이론에 기초하여 안테나의 형태를 서로 다르게 제작하였다. 논문에서 제안하는 MIMO 안테나는 각각 PIFA와 슬롯 안테나로 구성되어 있고, 두 개 모두 PIFA(Planar Inverted F Antenna)로 제작한 경우와 상관도 성능을 비교하였다. 서로 다른 구조의 두 개의 PIFA 타입으로 제작된 MIMO 안테나의 평균 상관 계수는 0.71로 매우 높았으나, 본 논문에서 제안된 MIMO 안테나는 0.17로 상관도 특성이 매우 낮아짐을 확인할 수 있었다.

• 한국미생물·생명공학회지
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• 제49권2호
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• pp.181-191
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• 2021

The present study addresses isolation, optimization, partial purification, and characterization of a haloalkaline serine protease from a newly isolated haloarchaeal strain isolated from Wadi El Natrun in Egypt. We expected that a two-step sequential statistical approach (one variable at a time, followed by response surface methodology) might maximize the production of the haloalkaline serine protease. The enzyme was partially purified using Hiprep 16/60 sephacryl S-100 HR gel filtration column. Molecular identification revealed the newly isolated haloarchaeon to be Natrialba hulunbeirensis strain WNHS14. Among several tested physicochemical determinants, casamino acids, KCl, and NaCl showed the most significant effects on enzyme production as determined from results of the One-Variable-At-A-time (OVAT) study. The BoxBehnken design localized the optimal levels of the three key determinants; casamino acids, KCl, and NaCl to be 0.5% (w/v), 0.02% (w/v), and 15% (w/v), respectively, obtaining 62.9 U/ml as the maximal amount of protease produced after treatment at 40℃, and pH 9 for 9 days with 6-fold enhancement in yield. The enzyme was partially purified after size exclusion chromatography with specific activity, purification fold, and yield of 1282.63 U/mg, 8.9, and 23%, respectively. The enzyme showed its maximal activity at pH, temperature, and NaCl concentration optima of 10, 75℃, and 2 M, respectively. Phenylmethylsulfonyl fluoride (PMSF, 5 mM) completely inhibited enzyme activity.