• Title/Summary/Keyword: Ionizing radiation

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Near-IR Polarization of the Northeastern Region of the Large Magellanic Cloud

  • Kim, Jaeyeong
    • The Bulletin of The Korean Astronomical Society
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    • v.42 no.2
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    • pp.42.2-42.2
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    • 2017
  • The Large Magellanic Cloud (LMC) is a unique target to study the detail structures of molecular clouds and star-forming regions, due to its proximity and face-on orientation from us. Most part of the astrophysical subjects for the LMC have been investigated, but the magnetic field is still veiling despite its role in the evolution of the interstellar medium (ISM) and in the main force to influence the star formation process. Measuring polarization of the background stars behind interstellar medium allows us to describe the existence of magnetic fields through the polarization vector map. In this presentation, I introduce the near-infrared polarimetric results for the $39^{\prime}{\times}69^{\prime}$ field of the northeastern region of the LMC and the N159/N160 star-forming complex therein. The polarimetric observations were conducted at IRSF/SIRPOL 1.4 m telescope. These results allow us to examine both the global geometry of the large-scale magnetic field in the northeastern region and the close structure of the magnetic field in the complex. Prominent patterns of polarization vectors mainly follow dust emission features in the mid-infrared bands, which imply that the large-scale magnetic fields are highly involved in the structure of the dust cloud in the LMC. In addition, local magnetic field structures in the N159/N160 star-forming complex are investigated with the comparison between polarization vectors and molecular cloud emissions, suggesting that the magnetic fields are resulted from the sequential formation history of this complex. I propose that ionizing radiation from massive stellar clusters and the expanding bubble of the ionized gas and dust in this complex probably affect the nascent magnetic field structure.

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Trapping and Detrapping of Transport Carriers in Silicon Dioxide Under Optically Assisted Electron Injection

  • Kim, Hong-Seog
    • JSTS:Journal of Semiconductor Technology and Science
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    • v.1 no.3
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    • pp.158-166
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    • 2001
  • Based on uniform hot carrier injection (optically assisted electron injection) across the $Si-SiO_2$ interface into the gate insulator of n-channel IGFETs, the threshold voltage shifts associated with electron injection of $1.25{\times}l0^{16}{\;}e/\textrm{cm}^2 between 0.5 and 7 MV/cm were found to decrease from positive to negative values, indicating both a decrease in trap cross section ($E_{ox}{\geq}1.5 MV/cm$) and the generation of FPC $E_{ox}{\geq}5{\;}MV/cm$). It was also found that FNC and large cross section NETs were generated for $E_{ox}{\geq}5{\;}MV/cm$. Continuous, uniform low-field (1MV/cm) electron injection up to $l0^{19}{\;}e/\textrm{cm}^2 is accompanied by a monatomic increase in threshold voltage. It was found that the data could be modeled more effectively by assuming that most of the threshold voltage shift could be ascribed to generated bulk defects which are generated and filled, or more likely, generated in a charged state. The injection method and conditions used in terms of injection fluence, injection density, and temperature, can have a dramatic impact on what is measured, and may have important implications on accelerated lifetime measurements.

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Effects of Rad51 on Survival of A549 Cells

  • Yu, Sha-Sha;Tu, Yi;Xu, Lin-Lin;Tao, Xue-Qin;Xu, Shan;Wang, Shan-Shan;Xiong, Yi-Feng;Mei, Jin-Hong
    • Asian Pacific Journal of Cancer Prevention
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    • v.16 no.1
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    • pp.175-179
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    • 2015
  • Rad51, a key factor in the homologous recombination pathway for the DNA double-strand break repair, plays a vital role in genesis of non-small-cell lung cancer (NSCLC). In recent years, more and more studies indicate that high expression of Rad51 is of great relevance to resistance of NSCLC to chemotherapeutic agents and ionizing radiation. However, the underlying molecular mechanisms are poorly understood. In this study, we investigated the role of single Rad51 on cell viability in vitro. Our results show that depletion of endogenous Rad51 is sufficient to inhibit the growth of the A549 lung cancer cell line, by accumulating cells in G1 phase and inducing cell death. We conclude that independent Rad51 expression is critical to the survival of A549 cells and can be an independent prognostic factor in NSCLC patients.

Screening Methods for the Identification of Irradiated Foods

  • Shahbaz, Hafiz Muhammad;Ahn, Jae-Jun;Akram, Kashif;Kwon, Joong-Ho
    • Current Research on Agriculture and Life Sciences
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    • v.31 no.1
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    • pp.1-10
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    • 2013
  • The exposure of food to ionizing radiation has been recognized as a safe and effective mode of food preservation in more than 55 countries. The benefits include eradication of insect pests, inactivation of food pathogens, extension of shelf-life, and improvement in food hygiene. Regulatory authorities around the world have emphasized the implementation of various national and international regulations to facilitate trade and development of consumers' confidence in purchasing irradiated foods. Therefore, the need for reliable irradiation detection methods has increased to enforce these regulations. At present, a number of promising analytical approaches have been developed and evaluated. Moreover, about 10 European Standards have been adopted as General CODEX Alimentarius methods for the detection of irradiated foodstuffs. However, most of these methods demand relatively expensive equipment and prolonged sample preparation. Therefore, simple and cost-effective approaches would be advantageous for rapid screening of foodstuffs. The suspected samples need to be analyzed further with more validated techniques to confirm the screening results. In this review, existing screening methods (i.e. physical, chemical, and biological) for the identification of irradiated foods have been outlined along with their principles, scopes and limitations.

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Protective Effect of Fisetin (3,7,3',4'-Tetrahydroxyflavone) against γ-Irradiation-Induced Oxidative Stress and Cell Damage

  • Piao, Mei Jing;Kim, Ki Cheon;Chae, Sungwook;Keum, Young Sam;Kim, Hye Sun;Hyun, Jin Won
    • Biomolecules & Therapeutics
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    • v.21 no.3
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    • pp.210-215
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    • 2013
  • Ionizing radiation can induce cellular oxidative stress through the generation of reactive oxygen species, resulting in cell damage and cell death. The aim of this study was to determine whether the antioxidant effects of the flavonoid fisetin (3,7,3',4'-tetrahydroxyflavone) included the radioprotection of cells exposed to ${\gamma}$-irradiation. Fisetin reduced the levels of intracellular reactive oxygen species generated by ${\gamma}$-irradiation and thereby protected cells against ${\gamma}$-irradiation-induced membrane lipid peroxidation, DNA damage, and protein carbonylation. In addition, fisetin maintained the viability of irradiated cells by partially inhibiting ${\gamma}$-irradiation-induced apoptosis and restoring mitochondrial membrane potential. These effects suggest that the cellular protective effects of fisetin against ${\gamma}$-irradiation are mainly due to its inhibition of reactive oxygen species generation.

Effects of Ionizing Radiation on the Extraction Yield and Viscosity of Alginate (알진산(酸)의 추출수율(抽出收率) 및 점성(粘性)에 미치는 방사선의 영향)

  • Yang, Jae-Seung;Lee, Su-Rae
    • Korean Journal of Food Science and Technology
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    • v.9 no.3
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    • pp.194-198
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    • 1977
  • A seaweed Ecklonia cava from Jeju island was irradiated with $0.1{\sim}6\;Mrad$ of gamma-rays and the yield and viscosity characteristics of alginates from it were examined. Irradiation below 1 Mrad dose brought about a 70% increase in the yield while higher doses caused slight decreases. Viscosity behavior of alginates below 0.5 Mrad dose was not altered while the viscosity decreased markedly above 1 Mrad dose, likely due to the depolymerization.

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DNA Strand Breaks in Mitotic Germ Cells of Caenorhabditis elegans Evaluated by Comet Assay

  • Park, Sojin;Choi, Seoyun;Ahn, Byungchan
    • Molecules and Cells
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    • v.39 no.3
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    • pp.204-210
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    • 2016
  • DNA damage responses are important for the maintenance of genome stability and the survival of organisms. Such responses are activated in the presence of DNA damage and lead to cell cycle arrest, apoptosis, and DNA repair. In Caenorhabditis elegans, double-strand breaks induced by DNA damaging agents have been detected indirectly by antibodies against DSB recognizing proteins. In this study we used a comet assay to detect DNA strand breaks and to measure the elimination of DNA strand breaks in mitotic germline nuclei of C. elegans. We found that C. elegans brc-1 mutants were more sensitive to ionizing radiation and camptothecin than the N2 wild-type strain and repaired DNA strand breaks less efficiently than N2. This study is the first demonstration of direct measurement of DNA strand breaks in mitotic germline nuclei of C. elegans. This newly developed assay can be applied to detect DNA strand breaks in different C. elegans mutants that are sensitive to DNA damaging agents.

CHEMICAL ABUNDANCES OF THE SYMBIOTIC NOVA AG PEGASI

  • Kim, Hyouk;Hyung, Siek
    • Journal of The Korean Astronomical Society
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    • v.41 no.2
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    • pp.23-37
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    • 2008
  • The high-resolution optical region spectroscopic data of the symbiotic nova AG Peg secured with the Hamilton Echelle Spectrograph at the Lick Observatory, have been analyzed along with the International Ultraviolet Explorer UV archive data. We measure about 700 line intensities in the wavelengths of 3859 to $9230{\AA}$ and identify about 300 lines. We construct pure photoionization models that represent the observed lines and the physical condition for this symbiotic nova. The spectral energy distribution of the ionizing radiation is adopted from stellar model atmospheres. Based on photoionization models, we derive the elemental abundances; C & N appear to be similar to be smaller than the Galactic planetary nebular value while O is enhanced. Our result is compared with the Contini (1997, 2003) who analyzed the UV region spectral data with the shock + ionization model. The Fe abundance appears to be enhanced than that of normal planetary nebulae, which suggests that AG Peg may have formed in the Galactic disk. The models indicate that the temperature of the central star which excite the shell gas may have fluctuated to an unexpected extent during the years 1998 - 2002.

The Study on the Design and Implementation of SHF band Upconverter of Digital Satellite Communication (디지털위성중계기용 SHF 대역 상향주파수 변환장치 설계 및 구현에 대한 연구)

  • Kim, Ki-Jung
    • The Journal of the Korea institute of electronic communication sciences
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    • v.12 no.2
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    • pp.261-266
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    • 2017
  • This study describes the design and implementation of SHF band Upconverter Digital Satellite Communication. The SHF band Upconverter unit consists of PLDROand frequency converter. In frequency converter, microstripBPF and LPF designed through the pre EMsimulation are implemented to minimize the unwanted spurious in frequency converter. Through the pre-simulation analysis ofspace environment, the possibility of and minimized about the malfunction of equipment and we designed a reliable SHF band Upconverter through simulation for a TID according to the vibration generated during the launch and space radiation environment, and compared pre-simulation of main performance results to test results about main performances of SHF band Upconverter after production.

Clinical Usefulness of Ultrasonography in Oral and Maxillofacial Regions (구강악안면영역에서 초음파영상 진단)

  • Oh, Song Hee;Choi, Yong-Suk
    • The Journal of the Korean dental association
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    • v.57 no.11
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    • pp.690-699
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    • 2019
  • Ultrasound sonography(US) is used to evaluate various diseases of maxillofacial region including salivary glands, soft tissue and jaw lesions because of easy accessibility and no hazard of ionizing radiation. Also, US can offer dynamic study showing real-time images during diagnostic or surgical procedure. US images provide accurate information about the internal features of lesions on the jaw prior to surgical treatment. Doppler images are used to visualize the vascular distribution of the lesions and to provide additional information to enhance diagnostic value. Nevertheless, the clinical application of US imaging is limited in the dental field. This is due to the lack of knowledge about the US image and the image characteristics of the anatomical structures. It is necessary to evaluate the diagnostic value of US and evaluate its usefulness by looking at clinical cases using US images. Therefore, US imaging may be recommended as an assistant image in evaluating jaw lesions. US images provided accurate information about the internal structure of lesions on the jaw prior to surgical treatment, and diagnostic value was enhanced by visualizing the vascular distribution of the lesion using doppler imaging.

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